Arterial Intimal Fibrosis in Reperfusion Biopsy Correlates with Graft Function after Kidney Transplant.

abstract：:Platelet activation is commonly monitored with a battery of monoclonal antibodies against different platelet epitopes with controversial results. The transient expression of platelet markers and their role mediating interactions with other cells could easily explain these discrepancies. The present study has evaluated...

journal_title：Nephron

authors： Hernández MR,Galán AM,Lozano M,Bozzo J,Cases A,Escolar G,Calls J,Ordinas A

更新日期：1998-10-01 00:00:00

abstract：INTRODUCTION:In an attempt to decrease mortality in patients with end-stage renal disease, an increase in the lifetime of these patients without much focus on health-related quality of life (HRQOL) was pursued for a long period of time. However, lately, an improvement in the quality of this extended lifetime has focuse...

journal_title：Nephron

authors： Grincenkov FR,Fernandes N,Pereira Bdos S,Bastos K,Lopes AA,Finkelstein FO,Pecoits-Filho R,Qureshi AR,Divino-Filho JC,Bastos MG

更新日期：2015-01-01 00:00:00

abstract：:The effect of uremia upon the hepatic clearance rate of prednisone was studied in isolated perfused livers of normal and uremic female rats. The perfusion rate was kept at a constant flow rate of 25 ml/min. In order to induce uremia, one group of rats was 5/6 nephrectomized 3 weeks prior to the perfusions. The concent...

journal_title：Nephron

authors： Egfjord W,Langhoff E,Daugaard H,Olgaard K

更新日期：1987-01-01 00:00:00

abstract：:To understand the regulation of vasopressin receptors in an animal model of hypertension, localization and age-related changes in renal arginine vasopressin (AVP) receptors in spontaneously hypertensive rats (SHR) were investigated using in vitro (macro) autoradiography and a radiolabeled receptor assay. Autoradiograp...

journal_title：Nephron

authors： Hosoya M,Ogura T,Watanabe H,Ota Z,Kageyama Z

更新日期：1996-01-01 00:00:00

abstract：:In 25 patients with nephrotic syndromes of different origin, indomethacin caused an immediate decrease in glomerular filtration rate (GFR) and urinary protein excretion. This effect of indomethacin on GFR and proteinuria was more pronounced when the renin-angiotensin system was stimulated by a low-sodium diet and 50 m...

journal_title：Nephron

authors： Donker AJ,Brentjens JR,van der Hem GK,Arisz L

更新日期：1978-01-01 00:00:00

abstract：:The effects of intravenous iron, with and without androgens, was studied in a group of 39 patients treated by regular haemodialysis, almost all of whom had normal serum iron concentrations. Intravenous iron 1-2 g every 4 months produced a significant rise in haemoglobin from 6.3 to 7.9 g/dl in 17 female patients with ...

journal_title：Nephron

authors： von Hartitzsch B,Kerr DN

更新日期：1976-01-01 00:00:00

abstract：:Serum prolactin levels were elevated in male Sprague-Dawley rats with acute renal failure induced by glycerol administration. Specific prolactin binding to kidney membrane preparations was reduced in glycerol and antirat glomerular basement membrane serum-treated rats, after morphological and biochemical acute renal f...

journal_title：Nephron

authors： Dobbie JW,Mountjoy K,Cowden EA,Allison ME,Ratcliffe JG

更新日期：1981-01-01 00:00:00

abstract：:A 55-year-old woman was admitted to our hospital, complaining of general malaise, muscular weakness, anorexia and weight loss. She had a history of ingesting of a certain germanium (Ge) compound over the preceding 19 months, with a total dose of 47 g as Ge element. She was found to have renal failure (blood urea nitro...

journal_title：Nephron

authors： Takeuchi A,Yoshizawa N,Oshima S,Kubota T,Oshikawa Y,Akashi Y,Oda T,Niwa H,Imazeki N,Seno A

更新日期：1992-01-01 00:00:00

abstract：:Efficacy and safety of a low-molecular-weight heparin (LMWH) were studied in 33 stable maintenance hemodialysis patients who had a bleeding tendency on unfractionated heparin. The optimal dose of LMWH for each patient was titrated before the study; the mean total LMWH dosage was 1,152 +/- 574 IU. No major bleeding or ...

journal_title：Nephron

authors： Leu JG,Chiang SS,Lin SM,Pai JK,Jiang WW

更新日期：2000-12-01 00:00:00

abstract：:A 65-year-old man with sclerosing mesenteritis developed the nephrotic syndrome. Percutaneous renal biopsy revealed classical histologic findings of minimal change nephropathy with a mild interstitial nephritis. Immunomodulation with prednisone led to a rapid and complete remission of the proteinuria but did not alter...

journal_title：Nephron

authors： Vernace MA,Bellucci AG,Mossey RT,Susin M,Mailloux LU,Wilkes BM,Katz S,Eskreis D

更新日期：1996-01-01 00:00:00

abstract：:Mitochondria contain electron-dense particles, partly composed of an amorphous form of calcium phosphate. We have used electron microscopy from percutaneous renal biopsy material to analyze mitochondrial granulation in the proximal renal tubule of nonuremic and uremic children. Based on a technique of cutting mitochon...

journal_title：Nephron

authors： Whitney JO,Goodman JR,Piel CF

更新日期：1979-01-01 00:00:00

abstract：:Like other biguanide agents, metformin is an anti-hyperglycemic agent with lower tendency towards hypoglycemia compared to other anti-diabetic drugs. Given its favorable effects on serum lipids, obese body habitus, cardiovascular disease, and mortality, metformin is recommended as the first-line pharmacologic agent fo...

journal_title：Nephron

authors： Rhee CM,Kovesdy CP,Kalantar-Zadeh K

更新日期：2017-01-01 00:00:00

abstract：:A 37-year-old female presented with acute onset of glomerulonephritis 10 days following an upper respiratory infection. Serum complement components were depressed and proteinuria exceeded 3.0 g daily. Renal biopsy revealed granular staining of IgG and C3 along the basement membrane as well as small amounts of IgA in a...

journal_title：Nephron

authors： Yoshizawa N,McClung JA,Ohshima S,Takahashi K,Treser G

更新日期：1986-01-01 00:00:00

abstract：:The effect of ischemia on renal blood flow (RBF) in the rat has been an unsettled question. This study used a totally extractable indicator, radioactive microspheres, with a reference arterial sample, to study RBF quantitatively 10 and 60 min after 1 h of unilateral renal artery clamping in anesthetized, heparinized r...

journal_title：Nephron

authors： Riley AL

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND/AIMS:De novo expression of CD44 is considered as a marker of parietal epithelial cell (PEC) activation. The aim of our study was to explore CD74 expression, which can form a complex with CD44, in PECs during the progression of focal segmental glomerulosclerosis (FSGS). To clarify the role of CD74 expression ...

journal_title：Nephron

authors： Yamazaki T,Sasaki S,Okamoto T,Sato Y,Hayashi A,Ariga T

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIM:Interleukin-6 (IL-6) promotes the growth of renal mesangial cells. IL-6 may play a major role in such mesangial proliferation, but there has been little research on IL-6 in relation to diabetic nephropathy because of the difficulty in measuring urinary and serum IL-6 levels. Using a newly developed, high...

journal_title：Nephron

authors： Shikano M,Sobajima H,Yoshikawa H,Toba T,Kushimoto H,Katsumata H,Tomita M,Kawashima S

更新日期：2000-05-01 00:00:00

abstract：:Clearance and in vitro microperfusion studies were performed in rabbits to determine the effect of cisplatin on proximal straight tubule transport of calcium and magnesium. Rabbits were injected with cisplatin (2.5 mg/kg i.p. once weekly) for 3 weeks, whereas control rabbits received normal saline solution which serve...

journal_title：Nephron

authors： Wong NL,Sutton RA,Dirks JH

更新日期：1988-01-01 00:00:00

abstract：:We studied the effects of oral furosemide, 80 mg/day for 7 days, on the response of urinary excretion of phosphate and cyclic AMP to exogenous parathyroid extract (PTE) in 6 normal subjects. All 6 subjects had marked increases in urinary calcium and a significant increase in urinary cyclic AMP from the control to the ...

journal_title：Nephron

authors： Fujita T,Delea CS,Bartter FC

更新日期：1985-01-01 00:00:00

abstract：CONTEXT:The widespread use of diuretics, potassium supplements, and medications that block renin angiotensin system puts the chronic kidney disease (CKD) population at high risk for dyskalemia, both hyperkalemia and hypokalemia. The optimal potassium level in a CKD patient is unknown. Subject of review: Two recent stud...

journal_title：Nephron

authors： Tandukar S,Fried LF

更新日期：2018-01-01 00:00:00

abstract：:The decarboxylation and transamination reactions of glyoxylate, which divert this precursor from oxalate formation, have been investigated. Decarboxylation of glyoxylate is synergistic with 2-oxoglutarate and catalysed by 2-oxoglutarate:glyoxylate carboligase which co-chromatographs with the 2-oxoglutarate dehydrogena...

journal_title：Nephron

authors： Bais R,Rofe AM,Conyers RA

更新日期：1991-01-01 00:00:00

abstract：:The cytokines tumor necrosis factor-alpha (TNF-alpha) and its soluble TNF receptors 55 and 75 (sTNFR55, sTNFR75), interleukin-1 beta (IL-1BETA) and interleukin-6 (IL-6) were measured in plasma from 13 patients with the hemolytic uremic syndrome (HUS) on admission. No significant changes in the plasma levels of TNF-alp...

journal_title：Nephron

authors： van de Kar NC,Sauerwein RW,Demacker PN,Grau GE,van Hinsbergh VW,Monnens LA

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND/AIMS:Anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) is a cause of biopsy-proven acute kidney injury, more common in the elderly. Treatment requires immunosuppression, which can have significant toxic effects. The aim of this study was to assess whether morbidity and mortality that are a...

journal_title：Nephron

authors： Judge PK,Reschen ME,Haynes R,Sharples EJ

更新日期：2016-01-01 00:00:00

abstract：:In 2014 57.5% of HD patients and 62.7% of PD patients achieved the audit measure for phosphate. 29.0% of HD and 30.3% of PD patients had a serum phosphate above the audit standard range. 79.1% of HD and 79.7% of PD patients had adjusted calcium between 2.2–2.5 mmol/L. 57.4% of HD and 65.0% of PD patients had a serum P...

journal_title：Nephron

authors： Nicholas J,Evans R,Shaw C,Dawnay A

更新日期：2016-01-01 00:00:00

abstract：:The course of left ventricular hypertrophy was investigated in anemic hemodialysis patients treated with recombinant human erythropoietin (r-huEPO). 12 patients, aged 60.8 +/- 9.9 years (mean +/- SD) were treated for 18.8 +/- 2.7 months. Left ventricular size was estimated by echocardiography performed before treatmen...

journal_title：Nephron

authors： Zehnder C,Zuber M,Sulzer M,Meyer B,Straumann E,Jenzer HR,Blumberg A

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The epithelial-mesenchymal transition (EMT) is a crucial event in the development of renal interstitial fibrosis (RIF). A growing body of evidence indicates that β-catenin plays an important role in various types of fibrosis. Although members of the microRNA (miRNA)-200 family have been suggested to suppress...

journal_title：Nephron

authors： Gong Y,Qin Z,Zhou B,Chen H,Shi Z,Zhang J

更新日期：2017-01-01 00:00:00

abstract：:Cardiovascular disease is the major complication and cause of mortality in the dialysis population, accounting for about 40% of deaths. Oxidative stress has been strongly implicated in the pathogenesis of these events. As patients in end-stage renal disease (ESRD) are in a state of elevated free radical activity, the ...

journal_title：Nephron

authors： Wang NP,Lim PS,Chen TT,Thien LM,Wang TH,Hsu WM

更新日期：2002-12-01 00:00:00

abstract：:Urinary excretion of oxalate, calcium and urate has been investigated in 88 patients affected by idiopathic calcium oxalate stone disease and in 20 normal subjects. Of these ions, only oxalate was found significantly higher in stone formers. Defining hyperoxaluria as urinary oxalate excretion greater than 2 SD above n...

journal_title：Nephron

authors： Baggio B,Gambaro G,Favaro S,Borsatti A

更新日期：1983-01-01 00:00:00

abstract：:A 4-year-old girl, who had been in perfect health, presented with the acute onset of renal failure and abdominal mass. Investigations revealed a solitary left kidney which on histology had the typical features of xanthogranulomatous pyelonephritis. The child had no previous history suggestive of chronic renal disease ...

journal_title：Nephron

authors： Noah M,Schoeneman MJ,Haycock G,Levitt SB,Bennett B,Greifer I

更新日期：1978-01-01 00:00:00

abstract：:The expression of the adhesion molecules LFA-1 (CD11a-CD18), Mac-1 (CD11b-CD18), and LAM-1 on predialysis and intradialysis neutrophils (PMN) was analyzed by flow cytometry in 10 chronic hemodialysis patients (CHD) and compared with age-matched normal controls. All patients were dialyzed either with a polyacrylonitril...

journal_title：Nephron

authors： Zachée P,Daelemans R,Pollaris P,Boogaerts MA,Lins RL

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:Genetic cell ablation using the human diphtheria toxin receptor (hDTR) is a new strategy used for analysing cellular function. Diphtheria toxin (DT) is a cytotoxic protein that leaves mouse cells relatively unaffected, but upon binding to hDTR it ultimately leads to cell death. We used a podocyte-specif...

journal_title：Nephron

authors： Stevens M,Neal CR,Salmon AHJ,Bates DO,Harper SJ,Oltean S

更新日期：2018-01-01 00:00:00