Abstract：
:Striatal D-2 dopamine (DA) antagonist and agonist binding sites were measured during the rat estrous cycle and compared to ovariectomized (OVX) rats. Dopaminergic D-2 antagonist binding sites were constant during the estrous cycle while agonist binding sites show a rapid and significant decrease of the ratio of high to low D-2 agonist binding sites from proestrus AM (PAM) to diestrus 1 (D1) and return to OVX value in diestrus 2 (DII). Thus, physiological fluctuations of hormones as occur during the estrous cycle can modulate extrahypothalamic biogenic amine activity, namely striatal DA systems which are not involved in the control of hormone secretion.
journal_name
Life Scijournal_title
Life sciencesauthors
Di Paolo T,Falardeau P,Morissette Mdoi
10.1016/0024-3205(88)90137-3subject
Has Abstractpub_date
1988-01-01 00:00:00pages
665-72issue
8eissn
0024-3205issn
1879-0631pii
0024-3205(88)90137-3journal_volume
43pub_type
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