Abstract:
:Repeated, low-intensity electrical stimulation of the heart gradually leads to the development of electrocardiographic abnormalities that culminate in cardiac arrhythmias, mainly A-V block in the isolated heart frog and ventricular and supraventricular tachyarrhythmias in the canine heart in situ. The pattern of development of these alterations shows some characteristics similar to the kindling phenomenon. Blockade of adrenergic influences on the heart offered complete protection against the development of cardiac arrhythmias. These results support the idea that a kindling-like effect can be induced by the periodic electrical stimulation of structures other than the CNS.
journal_name
Life Scijournal_title
Life sciencesauthors
García-Márquez F,Moreno JA,Luján M,Rodríguez Rdoi
10.1016/0024-3205(88)90437-7subject
Has Abstractpub_date
1988-01-01 00:00:00pages
1591-5issue
17eissn
0024-3205issn
1879-0631pii
0024-3205(88)90437-7journal_volume
42pub_type
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