Abstract：
:A review of the rapidly accumulating data in the literature continues to support the notion that catecholamines regulate ovarian function, and extends the complexity of catecholaminergic effects on the ovary via interactions with pituitary and adrenal hormones. It is clear that catecholamines affect growth and differentiation of ovarian follicles, but their role in follicular rupture during ovulation and in corpus luteum function remains unclear. The effects of catecholamines (mediated by membrane receptors) on ovarian function probably should be considered paracrine but classic endocrine regulation of ovarian function cannot be ruled out. Myogenic tonus of ovarian vasculature appears to be regulated by catecholamines, and estrogens may enhance adrenergic receptors in ovarian smooth muscle cells.
journal_name
Life Scijournal_title
Life sciencesauthors
Spicer LJdoi
10.1016/0024-3205(86)90088-3subject
Has Abstractpub_date
1986-11-10 00:00:00pages
1701-11issue
19eissn
0024-3205issn
1879-0631pii
0024-3205(86)90088-3journal_volume
39pub_type
杂志文章,评审相关文献
LIFE SCIENCES文献大全abstract：:Acute post-ischemic cardiac failure was studied in isolated rat hearts. Xylitol, glutamine, aspartic acid and glycine were added during reperfusion, resulting in no inotropic effect. Concanavalin A had a moderate inotropic effect. When concanavalin A added with xylitol, glutamine, aspartic acid and glycine, a rapid re...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(93)90705-8
更新日期：1993-01-01 00:00:00
abstract：:The antinociceptive effect of the benzomorphan class of opioid analgesics have been difficult to measure utilizing some of the standard animal pain models. This may be due, in part, to the sedative and/or motor effects associated with these drugs. In addition, it has been proposed that the major site of action for dru...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(86)90270-5
更新日期：1986-01-06 00:00:00
abstract：:Cancer cachexia characterized by a chronic wasting syndrome, involves skeletal muscle loss and adipose tissue loss and resistance to conventional nutritional support. Cachexia is responsible for the reduction in quality and length of life of cancer patients. It also decreases the muscle strength of the patients. The p...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/j.lfs.2016.11.033
更新日期：2017-02-01 00:00:00
abstract：:The complexes of the type [PtCl(L2)(ACRAMTU)](NO3)2 (ACRAMTU = 1-[2-(acridin-9-ylamino)ethyl]-1,3-dimethylthiourea) were synthesized: PT-ACRAMTU (1), L2 = ethane-1,2-diamine (en); PT(dach)-ACRAMTU (2), L2 = (1R,2R)-1,2-diaminocyclohexane (dach); PT(pda-OH)-ACRAMTU (3), L2 = 2-hydroxy-1,3-propanediamine (pda-OH). The c...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2018.11.052
更新日期：2019-01-15 00:00:00
abstract：:Tifluadom, although structurally a 1,4 benzodiazepine, has no affinity for the 3H-flunitrazepam binding site, but is a potent displacer of 3H-bremazocine from its opioid binding site. Tifluadom is characterised as an opiate kappa-receptor agonist in vitro and in vivo with potent analgesic activity in animals and no de...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(82)90346-0
更新日期：1982-09-20 00:00:00
abstract：:The outbreak of COVID-19 in December 2019, has become an urgent and serious public health emergency. At present, there is no effective treatment or vaccine for COVID-19. Therefore, there is a crucial unmet need to develop a safe and effective treatment for COVID-19 patients. Mesenchymal stem cells (MSCs) are widely us...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/j.lfs.2020.118493
更新日期：2020-12-01 00:00:00
abstract：AIMS:The purpose of our investigative work has been to determine whether there can be therapeutic roles in the administration of sildenafil citrate, heparin and several neuropeptides on an animal model where gastric ulcers were induced with acetic acid, and to compare their efficacy. MATERIALS AND METHODS:The animals ...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2017.08.013
更新日期：2017-10-01 00:00:00
abstract：:Chlorin e(6) and its derivatives are promising sensitizers for photodynamic therapy (PDT). In order to compare the photodynamic effects of 8 novel derivatives of chlorin e(6) and to explore some mechanisms of their effects at the cellular level, we studied PDT-induced changes in bioelectric activity of crayfish mechan...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2003.09.053
更新日期：2004-03-12 00:00:00
abstract：AIMS:Fudosteine is a cysteine derivative that is used as an expectorant in chronic bronchial inflammatory disorders. It has been shown to decrease the number of goblet cells in an animal model. This study examined the effects of fudosteine on airway inflammation and remodeling in a murine model of chronic asthma. MAIN...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2013.03.022
更新日期：2013-05-30 00:00:00
abstract：:We studied Na,K-ATPase mRNA expression in cardiomyopathic (Bio 14.6) and normal (F1b) Syrian hamster ventricles. In Northern blot analysis, Na,K-ATPase alpha 1, alpha 2, alpha 3 and beta 1 isoform mRNAs were detected in 3-week-old Bio 14.6 and F1b hamster ventricles. We then investigated the expression of alpha 1 subu...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(94)00776-4
更新日期：1994-01-01 00:00:00
abstract：AIMS:Colorectal cancer (CRC) is one of the most common cancers with poor prognosis worldwide. The advent of immunotherapy has greatly improved survival in refractory patients of CRC. In this study, we aimed to identify reliable immune classification and biomarkers that predict immunotherapeutic responses in CRC patient...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2020.118368
更新日期：2020-11-15 00:00:00
abstract：:High concentrations of cocaethylene (EC), the ethyl ester of benzoylecgonine, were measured in the blood of individuals who had concurrently used cocaine and ethanol. Since the powerful reinforcing effects of cocaine appear to be dependent on inhibition of dopamine reuptake in brain, we compared the effects of EC on t...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(91)90217-y
更新日期：1991-01-01 00:00:00
abstract：:Both in men and rats, most of the ethanol ingested at a low dose is metabolized before it reaches the systemic circulation. Oxidation of ethanol (mainly in the stomach) accounts for the bulk of this effect. This "first pass" metabolism (FPM) may be viewed as a barrier which protects against the systemic toxicity of et...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(85)90470-9
更新日期：1985-08-12 00:00:00
abstract：:Inhaled antimuscarinics, often called anticholinergics in clinical medicine, are established as first line bronchodilators in COPD. Tiotropium has been developed as a new generation antimuscarinic following ipratropium. Tiotropium is a specific, highly potent antimuscarinic, demonstrating very slow dissociation from m...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/s0024-3205(98)00588-8
更新日期：1999-01-01 00:00:00
abstract：:The effect of intravenous administration of human epidermal growth factor on the splanchnic blood flows was examined in anesthetized dogs, using an ultrasonic transit-time volume flow meter. Human epidermal growth factor (0.1, 0.5 and 1 microgram/kg) significantly increased blood flows in the portal vein (36.9 +/- 7.4...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(90)90170-v
更新日期：1990-01-01 00:00:00
abstract：:Early induction of VEGF was studied in liver, kidney and lung of spontaneously diabetic rats. Western blot analysis, northern hybridization were applied to show the expression of VEGF in different organs. Radiolabelled hypoxia responsive element (HRE) and cAMP responsive element (CRE) oligonucleotides were assayed by ...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/s0024-3205(01)01327-3
更新日期：2001-10-12 00:00:00
abstract：:The mechanism of spontaneous coronary contractions was investigated in the rabbit. Arteries with intact endothelium did not spontaneously contract. However, spontaneous coronary contractions were generated after the removal of the endothelium. NG-nitro-L-arginine methyl ester and methylene blue, the inhibitors of the ...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(94)00492-7
更新日期：1994-01-01 00:00:00
abstract：:The content of lactic acid in red blood cells, plasma, and Ehrlich ascites tumor cells were measured by a gas-liquid chromatography using a column with a terephtalic acid support coated with polyethylene glycol-6000. The lactic acid contents were directly determined in aqueous samples, because they were converted to a...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(92)90407-g
更新日期：1992-01-01 00:00:00
abstract：:Persistent neurochemical changes consistent with parkinsonism have been reported in brains of mice treated with repeated high doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). We now report that ethanol or acetaldehyde potentiate MPTP-induced damage to mouse striatum. One hour after the combined treatments...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(87)90030-0
更新日期：1987-03-02 00:00:00
abstract：AIMS:Idiopathic pulmonary fibrosis continues to be a devastating clinical disorder for which there are few therapeutic options, and the pathogenesis of this disease remains largely unknown. Statins are inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in cholesterol biosynthesis, and they have been reported...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2013.10.026
更新日期：2013-12-18 00:00:00
abstract：:U-54494A, a 1,2-diamine anticonvulsant, and U-50488H, a structurally related agonist for opiate kappa receptors, were tested for effects on spontaneous and glutamate-evoked firing rates in cerebral cortex of urethane-anesthetized male Sprague-Dawley rats. Iontophoretic application of 1,2-diamines, glutamate diethyl et...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(92)90322-g
更新日期：1992-01-01 00:00:00
abstract：:The hyperphagia and rapid body weight gain normally observed in young obese (ob/ob) mice were abolished by removal of their adrenal glands, whereas food intake and weight gain of lean mice were not significantly affected by adrenalectomy. Adrenalectomy lowered body energy density (kcal/g carcass) in obese mice more th...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(84)90056-0
更新日期：1984-04-09 00:00:00
abstract：:Pulmonary surfactant release from lamellar bodies in alveolar type II cells in response to exogenous and circulating catecholamines is well documented but sympathetic influences from direct nerve stimulation are not as extensively studied. In order to study sympathetic nerve influence on release, ultrastructure of typ...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(94)00662-8
更新日期：1994-01-01 00:00:00
abstract：AIMS:Long non-coding RNAs (LncRNAs) play central roles in the formation and development of gastric cancer (GC). The aim of this study was to evaluate the expression of PURPL and NONHSAT062994 and the relationship between their expressions with clinical characteristics in GC. MAIN METHODS:PURPL and NONHSAT062994 LncRNA...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2019.116904
更新日期：2019-11-15 00:00:00
abstract：AIM:The purpose of this study was to investigate whether the flavonoid quercetin can prevent alterations in the behavioral tests and of cholinergic neurotransmission in rats submitted to the ethidium bromide (EB) experimental demyelination model during events of demyelination and remyelination. MAIN METHODS:Wistar rat...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2014.03.033
更新日期：2014-05-17 00:00:00
abstract：:PNA+Tempol, albumin containing conjugated (polynitroxyl albumin; PNA) and free (4-hydroxyl-2,2,6,6-tetramethyl-piperidinyl-1-oxyl; Tempol) nitroxide may protect against injury caused by reactive oxygen species. Therefore, the actions of PNA+Tempol on liver injury and inflammation induced by hepatic ischemia and reperf...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/s0024-3205(00)00907-3
更新日期：2000-11-17 00:00:00
abstract：AIMS:The role of estrogen in embryo implantation in golden hamster (Mesocricetus auratus) is still ambiguous. In order to clarify it, we investigated the spatial distribution and expression of estrogen receptors, ER-α and ER-β in the uterus of pregnant hamster during peri-implantation period and identified the effect o...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2016.12.002
更新日期：2017-02-01 00:00:00
abstract：:The infection epidemic event of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was formally declared a pandemic by World Health Organization on March 11th, 2020. Corona Virus Disease 2019 (COVID-19) is caused by SARS-CoV-2, a new type of coronavirus, which has high contagion and mainly causes respira...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/j.lfs.2020.118496
更新日期：2020-12-01 00:00:00
abstract：:Elevated total homocysteine concentrations and obesity are both associated with an increased risk of cardiovascular disease. However, previous studies of weight reduction on serum homocysteine concentrations have obtained inconsistent reports. We investigated the effect of folic acid supplementation on serum homocyste...
journal_title：Life sciences
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.lfs.2004.12.002
更新日期：2005-03-18 00:00:00
abstract：:A phencyclidine (PCP) receptor binding site has been solubilized in an active ligand-binding state from rat cerebral cortical membranes with sodium deoxycholate. Optimal receptor solubilization occurs at a detergent/protein ratio of 0.5 (w/w); for 5 mg protein/ml solubilized with 0.25% sodium deoxycholate, about 60% o...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(89)90567-5
更新日期：1989-01-01 00:00:00
