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Rapid and simple gas chromatographic measurement of lactic acid in red blood cells, plasma, and tumor cells after hyperthermia.

Abstract：

:The content of lactic acid in red blood cells, plasma, and Ehrlich ascites tumor cells were measured by a gas-liquid chromatography using a column with a terephtalic acid support coated with polyethylene glycol-6000. The lactic acid contents were directly determined in aqueous samples, because they were converted to a volatile derivative in the column. The method was rapid and simple, compared with previous methods which need time-consuming conversion of lactic acid to volatile derivatives. Our measurements showed the increase in the contents of intra- and extracellular lactic acid after hyperthermia.

journal_name

Life Sci

journal_title

Life sciences

authors

Kageyama K,Onoyama Y,Nakajima T,Tumura M,Nishida T,Kogawa H,Tanabe K

doi

10.1016/0024-3205(92)90407-g

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

407-10

issue

6

eissn

0024-3205

issn

1879-0631

pii

0024-3205(92)90407-G

journal_volume

51

pub_type

杂志文章

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