Abstract:
:Two types of plasma membranes isolated from rat brain cortex were used to study the membrane-perturbing properties of ethanol. Rats administered ethanol in the form of a liquid diet showed an increase in levels of phosphatidylserines, phosphatidylinositols and phosphatidic acids as compared to controls. The results present evidence that chronic ethanol treatment results in an increase in the acidic phospholipids in brain membranes. This type of membrane modification may have important implications for the function of membrane transport enzymes such as (Na+, K+)-ATPase, which also increases in activity upon chronic ethanol administration.
journal_name
Life Scijournal_title
Life sciencesauthors
Sun GY,Huang HM,Lee DZ,Sun AYdoi
10.1016/0024-3205(84)90512-5subject
Has Abstractpub_date
1984-11-19 00:00:00pages
2127-33issue
21eissn
0024-3205issn
1879-0631pii
0024-3205(84)90512-5journal_volume
35pub_type
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