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Elevated lipid peroxidation products and depleted transferrin levels in the plasma of kidney transplant recipients.

Abstract：

:Lipid peroxidation products were measured in the plasma of 24 kidney transplant patients and 12 healthy volunteers (controls) by: (1) 2-thiobarbituric acid assay and (2) the intensity of fluorescence products of malonaldehyde cross-linked proteins. Plasma levels of creatinine, ceruloplasmin, transferrin, prealbumin, albumin and total protein were also measured. Elevated lipid peroxidation products and lowered transferrin levels were observed in transplant patients compared to controls. Ceruloplasmin levels were slightly but significantly elevated in recent transplant recipients (less than 6 months, n = 12, Group A) while no difference was observed between older transplant recipients (greater than 6 months, n = 12, Group B) and controls. Serum, creatinine levels were also slightly but significantly elevated in both groups of patients compared to controls. Serum prealbumin, albumin and total protein levels in both groups of transplant recipients were not different from controls or reference range values.

journal_name

Life Sci

journal_title

Life sciences

authors

Dasgupta A,Powell D,Saldana S,Doria L

doi

10.1016/0024-3205(90)90059-z

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

67-72

issue

1

eissn

0024-3205

issn

1879-0631

pii

0024-3205(90)90059-Z

journal_volume

46

pub_type

杂志文章

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