Abstract:
:Superoxide dismutase (SOD), neuron specific enolase (NSE) and lactic dehydrogenase (LDH) were measured in the serum and cerebrospinal fluid (CSF) of ischemic cerebrovascular patients, other neurological patients and in age-matched healthy controls (serum only). The levels of SOD in the CSF or serum of the ischemic patients in the first 24 hrs after stroke were similar to the control groups. However, SOD levels in the ischemic patients increased after two days, reaching their peak values after one week (2-3 fold of the initial values). NSE showed a similar kinetics while LDH showed no change. These results suggest that oxygen radicals are formed in the ischemic patients and the increased synthesis of SOD may protect the patients from the potential damage of such radicals.
journal_name
Life Scijournal_title
Life sciencesauthors
Gruener N,Gross B,Gozlan O,Barak Mdoi
10.1016/0024-3205(94)90159-7subject
Has Abstractpub_date
1994-01-01 00:00:00pages
711-3issue
11eissn
0024-3205issn
1879-0631pii
0024-3205(94)90159-7journal_volume
54pub_type
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