Beneficial effects of melatonin on serum nitric oxide, homocysteine, and ADMA levels in fructose-fed rats.

abstract：CONTEXT:In traditional medicine propolis is widely used for the treatment of various ailments including ulcer and wound healing. The phytochemical screening of Indian propolis indicates the presence of biologically active ingredients in appreciable amounts. In the absence of systematic evaluation of wound healing prope...

journal_title：Pharmaceutical biology

authors： Iyyam Pillai S,Palsamy P,Subramanian S,Kandaswamy M

更新日期：2010-11-01 00:00:00

abstract：CONTEXT:1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines. OBJECTIVE:To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of 1 ...

journal_title：Pharmaceutical biology

authors： Sun J,Jiang T,Xu W,Feng Z,Quan X,Leng P,Sun W,Zhao J,Jing F,Li J

更新日期：2019-12-01 00:00:00

abstract：CONTEXT AND OBJECTIVE:The Sisala traditional healers of northwest Ghana have a rich ethnomedical tradition. The purpose of this study was to collect and analyse data on medicinal plants commonly used by Sisala traditional healers. METHODS:A total of 30 traditional healers were interviewed using a mixture of open- and ...

journal_title：Pharmaceutical biology

authors： Wodah D,Asase A

更新日期：2012-07-01 00:00:00

abstract：CONTEXT:Cardioprotective effects of various plants are generally attributed to their antioxidant activity. The whole fruit extract of pomegranate (WFEP), Punica granatum L. (Punicaceae), has a potent antioxidant activity. OBJECTIVE:To investigate cardioprotective effect of WFEP against doxorubicin (Dox)-induced cardio...

journal_title：Pharmaceutical biology

authors： Hassanpour Fard M,Ghule AE,Bodhankar SL,Dikshit M

更新日期：2011-04-01 00:00:00

abstract：:Abstract Context: Diabetes mellitus (DM) type 2 is a chronic disease characterized by hyperglycemia and insulin resistance. Oxidative stress participates in development and progression of DM, in which changes of superoxide dismutase (SOD) and catalase (CAT) were noted in DM mice. Berberine has been widely used as an a...

journal_title：Pharmaceutical biology

authors： Chatuphonprasert W,Lao-Ong T,Jarukamjorn K

更新日期：2013-11-05 00:00:00

abstract：CONTEXT:Oysters [Crassostrea plicatula Gmelin (Ostreidae)] are widely used for food in coastal areas. It is reported to have several qualities such as improving sexual and immune function. They has been approved by Chinese Ministry of Health as a functional food. OBJECTIVE:The effects of five types of oyster component...

journal_title：Pharmaceutical biology

authors： Hao G,Zhang C,Cao W,Hao J

更新日期：2014-06-01 00:00:00

abstract：CONTEXT:The poor prognostic outcome of breast cancer is largely due to its resistance to cancer therapies. Development of therapeutic agents that can inhibit growth and induce apoptosis in breast cancer cells can help solve the problem. Emodin is an active anthraquinone that has been reported to have diverse biological...

journal_title：Pharmaceutical biology

authors： Li WY,Chan RY,Yu PH,Chan SW

更新日期：2013-09-01 00:00:00

abstract：CONTEXT:Previous in vitro studies have demonstrated that emodin (1,3,8-trihydroxy-6-methyl-anthraquinone), an anthraquinone derivative from the rhizome of Rheum palmatum L., can inhibit the activation of P2X₇ receptors (P2X₇R) as a potential antagonist. However, the effects of emodin on P2X₇R-related inflammatory proce...

journal_title：Pharmaceutical biology

authors： Zhu S,Wang Y,Wang X,Li J,Hu F

更新日期：2014-01-01 00:00:00

abstract：:The novel compound 1'''-hydroxy-2''',3'''-epoxylupinifolin ( 1 ), together with three known prenylated flavanones were identified from the stem of Derris reticulata during our reinvestigation of the plant. The structures were determined by spectroscopic methods including detailed study of NMR spectral data (DEPT, 2D-C...

journal_title：Pharmaceutical biology

authors： Prawat H,Mahidol C,Ruchirawat S

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:The extraction method and the crude wound healing effects of sacchachitin from Ganoderma tsugae Murr. (Ganodermataceae) has been cited. However, its purity is still largely limited. OBJECTIVE:An improvement of the fractionation protocol to purify the sacchachitin from Ganoderma lucidum L. (Ganodermataceae) (SG...

journal_title：Pharmaceutical biology

authors： Chuang CM,Wang HE,Chang CH,Peng CC,Ker YB,Lai JE,Chen KC,Peng RY

更新日期：2013-01-01 00:00:00

abstract：:Physalis alkekengi L. (Solanaceae) is a popular plant in traditional European and Chinese folk medicine, and it has been reported to have many ethnopharmacological properties including antifungal, anti-cough, anti-inflammatory, analgesic, and febricide activities. Some active components from Physalis species have been...

journal_title：Pharmaceutical biology

authors： Helvaci S,Kökdil G,Kawai M,Duran N,Duran G,Güvenç A

更新日期：2010-02-01 00:00:00

abstract：CONTEXT:Eupatorium triplinerve Vahl (Asteraceae), popularly known as Japana, is widely used in folk medicine, due its analgesic, anticoagulant, antianorexic, antiparasitic, anthelmintic, sedative, antifungal, and antibacterial properties. OBJECTIVE:The present study evaluated the chemical composition and antimicrobial...

journal_title：Pharmaceutical biology

authors： Matos Lopes TR,de Oliveira FR,Malheiros FF,de Andrade MA,Monteiro MC,Baetas Gonçalves AC

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:Tranexamic acid is commonly used for curing abnormal bleeding in a variety of diseases. In a previous study, 12 different tetrahydro-2H-1,3,5-thiadiazine derivatives were synthesized from the amine group of tranexamic acid. Their antifibrinolytic and antimicrobial activities were compared with tranexamic acid. ...

journal_title：Pharmaceutical biology

authors： Avuloğlu-Yılmaz E,Yüzbaşıoğlu D,Özçelik AB,Ersan S,Ünal F

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Bombacaceae is a small family of the order Malvales and contains about 28 genera and 200 species. Members of this family are not only showy ornamentals but they possess significant economical and commercial reputation as well. In addition, various plant parts of several species are widely used as foods and trad...

journal_title：Pharmaceutical biology

authors： Refaat J,Desoky SY,Ramadan MA,Kamel MS

更新日期：2013-01-01 00:00:00

abstract：:Context Yellow tea containing the same catechins as other types of tea but in different proportions has been suggested to possess potent anticancer activities. Objective This study investigates the chemopreventive effect of yellow tea aqueous extract against N-nitrosodiethylamine (NDEA)-induced liver carcinogenesis in...

journal_title：Pharmaceutical biology

authors： Kujawska M,Ewertowska M,Adamska T,Ignatowicz E,Gramza-Michałowska A,Jodynis-Liebert J

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:Calotropis procera (Ait.) R. Br. (Asclepiadaceae), Ficus elastica Roxb. (Moraceae) and Zingiber officinale Roscoe (Zingiberaceae) have been traditionally used to treat many diseases. OBJECTIVE:The antischistosomal activity of these plant extracts was evaluated against Schistosoma mansoni. MATERIALS AND METHOD...

journal_title：Pharmaceutical biology

authors： Seif el-Din SH,El-Lakkany NM,Mohamed MA,Hamed MM,Sterner O,Botros SS

更新日期：2014-02-01 00:00:00

abstract：:Context: Curcumin, a polyphenolic compound extracted from the rhizome of the tropical plant Curcuma longa L. (Zingiberaceae), has been considered as a cancer chemopreventive drug by American National Cancer Institute.Objective: To examine the effect of curcumin on acute monocytic leukaemia SHI-1 cells in vivo.Material...

journal_title：Pharmaceutical biology

authors： Zhu G,Shen Q,Jiang H,Ji O,Zhu L,Zhang L

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Prunella vulgaris L. (Labiatae) is a perennial plant common in China and Europe and is rich in rosmarinic acid (RA), ursolic acid (UA), and oleanolic acid (OA). The dried spica of P. vulgaris has been used as traditional medicine in China for over a hundred years. To our best knowledge, no study has been conduc...

journal_title：Pharmaceutical biology

authors： Chen Y,Guo Q,Zhu Z,Zhang L

更新日期：2012-09-01 00:00:00

abstract：:Context Syzygium densiflorum Wall. ex Wight & Arn (Myrtaceae) has been traditionally used by local tribes of the Nilgiris, Tamil Nadu, India, for the treatment of diabetes, however, no definitive experimental studies are available. Objective This study investigates the antidiabetic, antihyperlipidaemic and antioxidant...

journal_title：Pharmaceutical biology

authors： Krishnasamy G,Muthusamy K,Chellappan DR,Subbiah N

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:Peripheral axon injury and degeneration are often mediated by oxidative stress and inflammation. The hydroalcoholic extract of the red propolis (HERP) has attracted great attention because of its antioxidant and anti-inflammatory activities. OBJECTIVE:The objective of this work is to study the effect of HERP o...

journal_title：Pharmaceutical biology

authors： Barbosa RA,Nunes TL,Nunes TL,da Paixão AO,Belo Neto R,Moura S,Albuquerque Junior RL,Cândido EA,Padilha FF,Quintans-Júnior LJ,Gomes MZ,Cardoso JC

更新日期：2016-01-01 00:00:00

abstract：:2-Formyl-1-hydroxyanthraquinone, along with ten other known anthraquinones (1-hydroxy-2-methylanthraquinone, nordamnacanthal, damnacanthal, lucidin-?-methyl ether, rubiadin, rubiadin-1-methyl ether, soranjidiol, morindone, morindone-5-methyl ether and alizarin-1-methyl ether), isolated from the roots of Morinda ellipt...

journal_title：Pharmaceutical biology

authors： Ali AM,Ismail NH,Mackeen MM,Yazan LS,Mohamed SM,Ho AS,Lajis NH

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:The nephron-protective efficacy of Abelmoschus manihot (Linn.) Medicus (Malvaceae) has been proved by randomized controlled clinical trial. OBJECTIVE:Flavonoids are main active components of A. manihot, which can be transformed into glucuronide/sulfate conjugates in vivo. Exploring the pharmacokinetic profile ...

journal_title：Pharmaceutical biology

authors： Guo J,Du L,Shang E,Li T,Liu Y,Qian D,Tang Y,Duan J

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Viola tianshanica Maxim. (Violaceae) is a perennial herb distributed in Central Asia, especially in the Xinjiang Uygur Autonomous Region (XUAR) of China. Preliminary study showed that the ethanol extract of the herb exhibited the anti-complement activity against the classical pathway, but the active components ...

journal_title：Pharmaceutical biology

authors： Qin Y,Wen Q,Cao J,Yin C,Chen D,Cheng Z

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:Propranolol, atenolol, and ICI118,551 are non-selective β-adrenergic receptor (AR), β1-AR, and β2-AR antagonists, respectively. OBJECTIVE:We investigated the efficacy of propranolol, atenolol, and ICI118,551 on proliferation, migration, and invasion of non-stimulated breast (MCF7), colon (HT-29), and hepatocel...

journal_title：Pharmaceutical biology

authors： Işeri OD,Sahin FI,Terzi YK,Yurtcu E,Erdem SR,Sarialioglu F

更新日期：2014-11-01 00:00:00

abstract：CONTEXT:Hippocratea africana (Willd.) Loes. ex Engl. (Celastraceae) root is used traditionally as an antipoison or antidote to treat liver diseases. OBJECTIVE:To evaluate antioxidative burst and hepatoprotective potentials of H. africana against paracetamol-induced liver injury in rats. MATERIALS AND METHOD:Antioxida...

journal_title：Pharmaceutical biology

authors： Okokon JE,Nwafor PA,Charles U,Dar A,Choudhary MI

更新日期：2013-07-01 00:00:00

abstract：CONTEXT:Different parts of Punica granatum Linn. (Punicaceae) are traditionally used as renal protective agents in the Indian system of medicine. However, there is paucity of information regarding its role in diabetic nephropathy. OBJECTIVE:The present study investigates the nephroprotective potential of flavonoid-ric...

journal_title：Pharmaceutical biology

authors： Ankita P,Deepti B,Nilam M

更新日期：2015-01-01 00:00:00

abstract：:The approach to new drugs through natural products has proved to be the single most successful strategy for the discovery of new drugs, but in recent years its use has been deemphasized by many pharmaceutical companies in favor of approaches based on combinatorial chemistry and genomics, among others.Drug discovery fr...

journal_title：Pharmaceutical biology

authors： Cao S,Kingston DG

更新日期：2009-08-01 00:00:00

abstract：CONTEXT:Raspberry ketone (RK) is a natural phenolic compound of red raspberry. The dietary intake of RK has been reported to exert anti-obese actions and alter the lipid metabolism in vivo and human studies. OBJECTIVE:To elucidate a possible mechanism for anti-obese actions of RK, the effects of RK on the adipogenic a...

journal_title：Pharmaceutical biology

authors： Park KS

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:Sheng-Mai-San (SMS) has been used for the treatment of cardiovascular disease for many years in China. OBJECTIVES:This study investigated the protective effects and active ingredients of SMS on myocardial injury (MI) in mice. MATERIALS AND METHODS:SMS and n-butanol extraction of SMS (SMS-Bu) were prepared and...

journal_title：Pharmaceutical biology

authors： Wang YQ,Zhang JQ,Liu CH,Zhu DN,Yu BY

更新日期：2013-10-01 00:00:00

abstract：CONTEXT:Several studies have demonstrated that essential oils and their major components have antioxidant activity. p-Cymene is a monoterpene and a major constituent of essential oils of various species of plants. OBJECTIVE:This paper evaluated the antioxidant potential of p-cymene in the hippocampus of mice by determ...

journal_title：Pharmaceutical biology

authors： de Oliveira TM,de Carvalho RB,da Costa IH,de Oliveira GA,de Souza AA,de Lima SG,de Freitas RM

更新日期：2015-03-01 00:00:00