Antiviral, cyototoxic and antimicrobial activities of anthraquinones isolated from the roots of morinda elliptica.

abstract：CONTEXT:Total glucosides of peony (TGP), compounds extracted from the dried roots of Paeonia lactiflora Pall, have been reported to have anti-inflammatory and antioxidative activities. However, the protective effect of TGP on liver injury and the underlying mechanisms remains unknown in diabetic rats. OBJECTIVES:Curre...

journal_title：Pharmaceutical biology

authors： Xia LL,Zhu QJ,Wu YG

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:There have been no reports of the extraction of essential oil (EO) from white cabbage [Brassica oleracea L. var. capitata (L.) Alef. f. alba DC. (Brassicaceae)] (Bocfal) or its chemical composition, antioxidant activity, or hepatoprotective effects. OBJECTIVE:To extract Bocfal EO, to identify and quantify its ...

journal_title：Pharmaceutical biology

authors： Morales-López J,Centeno-Álvarez M,Nieto-Camacho A,López MG,Pérez-Hernández E,Pérez-Hernández N,Fernández-Martínez E

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:The fruit of the Prunus mume Sieb. et Zucc (Rosaceae) is used as a health food or medicinal material in traditional herb medicine for a long time in Eastern Asian countries. OBJECTIVE:Our present study investigated the hypouricemic effect of the methanol extract from P. mume fruit (MPMF) in mice with potassium...

journal_title：Pharmaceutical biology

authors： Yi LT,Li J,Su DX,Dong JF,Li CF

更新日期：2012-11-01 00:00:00

abstract：CONTEXT:Polygonum multiflorum is known as a medicinal plant. It has been used as a folk medicine which showed antioxidative property. OBJECTIVE:Protective effects of the water extracts (w/v:1/10) from fresh P. multiflorum (WEP) on carbon tetrachloride (CCl(4))-induced liver damage in rats were investigated. MATERIALS...

journal_title：Pharmaceutical biology

authors： Lee BH,Huang YY,Duh PD,Wu SC

更新日期：2012-03-01 00:00:00

abstract：CONTEXT:Despite phytochemical studies of Agrimonia pilosa Ledeb. (Rosaceae), the antidiabetic effects of this plant are unknown. OBJECTIVE:This study characterizes the isolated compounds from the aerial parts of A. pilosa and evaluates their PTP1B and α-glucosidase inhibitory properties. MATERIALS AND METHODS:Ethanol...

journal_title：Pharmaceutical biology

authors： Na B,Nguyen PH,Zhao BT,Vo QH,Min BS,Woo MH

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Glycosmis pentaphylla (Retz.) DC (Rutaceae) is a shrub, traditionally used to treat anemia, rheumatism, as an anthelmintic, febrifuge and vermifuge, for jaundice, and liver complaints. OBJECTIVE:This study evaluated the hepatoprotective activity of G. pentaphylla against paracetamol-induced hepatotoxicity in S...

journal_title：Pharmaceutical biology

authors： Nayak SS,Jain R,Sahoo AK

更新日期：2011-02-01 00:00:00

abstract：CONTEXT:The nephron-protective efficacy of Abelmoschus manihot (Linn.) Medicus (Malvaceae) has been proved by randomized controlled clinical trial. OBJECTIVE:Flavonoids are main active components of A. manihot, which can be transformed into glucuronide/sulfate conjugates in vivo. Exploring the pharmacokinetic profile ...

journal_title：Pharmaceutical biology

authors： Guo J,Du L,Shang E,Li T,Liu Y,Qian D,Tang Y,Duan J

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Many plant extracts and compounds are being investigated for their cytotoxicity and hence their medicinal or therapeutic properties. Reports of toxicity studies with limonoid analogs have been sparse and have involved mainly crude extracts. In this study, individual natural limonoids have been isolated and thei...

journal_title：Pharmaceutical biology

authors： Fowles RG,Mootoo BS,Ramsewak RS,Khan A

更新日期：2012-02-01 00:00:00

abstract：:In the present study, the anxiolytic and sedative-hypnotic activities of polygalasaponins extracted from Polygala tenuifolia Willdenow (Polygalaceae) were determined in mice using hole-board, elevated plus maze, open field, and sodium pentobarbital-induced hypnosis tests. Moreover, the acute toxicity of polygalasaponi...

journal_title：Pharmaceutical biology

authors： Yao Y,Jia M,Wu JG,Zhang H,Sun LN,Chen WS,Rahman K

更新日期：2010-07-01 00:00:00

abstract：CONTEXT:The fruits of Aronia melanocarpa Elliot (Rosaceae), (black chokeberry), and Sambucus nigra L. (Caprifoliaceae), elderberries are rich in anthocyanins. Many studies have reported that anthocyanins are beneficial in diabetes due to their capacity to stimulate insulin secretion and reduce oxidative stress. OBJECT...

journal_title：Pharmaceutical biology

authors： Badescu M,Badulescu O,Badescu L,Ciocoiu M

更新日期：2015-04-01 00:00:00

abstract：CONTEXT:Investigating potential central nervous system (CNS) activities of Crataegus monogyna Jacq. (Rosaceae), hawthorn, fruit extracts. OBJECTIVE:Evaluating CNS effects and analgesic activities of hawthorn fruit extracts based on the traditional uses of the plant for neurosedative and pain killer actions. MATERIALS...

journal_title：Pharmaceutical biology

authors： Can OD,Ozkay UD,Oztürk N,Oztürk Y

更新日期：2010-08-01 00:00:00

abstract：:Context Diabetes is a global health challenge. Although large prospective clinical trials have shown that intensive control of blood glucose or blood pressure reduces the risk for development and progression of vascular complications in diabetes, a substantial number of diabetic patients still experience renal failure...

journal_title：Pharmaceutical biology

authors： Yamagishi S,Matsui T

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Recent studies have shown compound Danshen dripping pills (CDDP) could improve microcirculation in ischemic/reperfusion injury and other microvascular disorders. The mechanism for CDDP's role in microcirculation is not clear. OBJECTIVE:To explore the protective effects of CDDP on microvascular dysfunction. MA...

journal_title：Pharmaceutical biology

authors： Zhang Y,Zhao J,Ding R,Niu W,He Z,Liang C

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Cotinus coggygria Scop. (Anacardiaceae) leaves that were used as wound healing in traditional Balkan and Anatolian folk medicine, could be potentially effective in treating diabetic wounds. OBJECTIVE:This study investigates biochemical and histological effects of ethanol extract of C. coggygria (CCE) on excisi...

journal_title：Pharmaceutical biology

authors： Aksoy H,Sen A,Sancar M,Sekerler T,Akakin D,Bitis L,Uras F,Kultur S,Izzettin FV

更新日期：2016-11-01 00:00:00

abstract：:Proteins from Parkia speciosa Hassk. (Fabaceae) seeds were extracted and stepwise precipitated using ammonium sulfate. Proteins precipitated with 25% ammonium sulfate were separated by affinity chromatography on Affi-Gel Blue gel followed by protein liquid chromatography on Superdex 200. The protein Gj, which was iden...

journal_title：Pharmaceutical biology

authors： Chankhamjon K,Petsom A,Sawasdipuksa N,Sangvanich P

更新日期：2010-01-01 00:00:00

abstract：CONTEXT:Amaranthus spinosus Linn. (Amaranthaceae), commonly known as ''spiny pigweed'', is used in both Indian traditional system and folk medicine for treatment of infectious diseases for a long time in several traditional herbal medicinal preparations. A novel fatty acid [(14E, 18E, 22E, 26E)-methyl nonacosa-14, 18, ...

journal_title：Pharmaceutical biology

authors： Mondal A,Maity TK

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Silymarin, a flavonolignan from Silybum marianum (L.) Gaertn. (Asteraceae), has been reported to have antioxidant and anti-inflammatory properties. Therefore, it may be worthwhile to study the effect of silymarin on wound healing. OBJECTIVE:To evaluate the effect of silymarin on human fibroblast cells in an in...

journal_title：Pharmaceutical biology

authors： Sharifi R,Pasalar P,Kamalinejad M,Dehpour AR,Tavangar SM,Paknejad M,Mehrabani Natanzi M,Nourbakhsh M,Ahmadi Ashtiani HR,Akbari M,Rastegar H

更新日期：2013-03-01 00:00:00

abstract：CONTEXT:Withania (Solanaceae) species are known to be a rich source of withanolides, which have shown several biological properties. OBJECTIVE:To identify the compounds responsible for Withania adpressa Coss. antioxidant activity and further test them for their NF-κB inhibition and antiproliferative activity in multip...

journal_title：Pharmaceutical biology

authors： Ben Bakrim W,El Bouzidi L,Nuzillard JM,Cretton S,Saraux N,Monteillier A,Christen P,Cuendet M,Bekkouche K

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Virgin coconut oil (VCO) has been reported to possess antioxidative, anti-inflammatory and anti-stress properties. OBJECTIVE:Capitalizing on these therapeutic effects, this study investigated for the first time the potential of VCO on memory improvement in vivo. MATERIALS AND METHODS:Thirty male Wistar rats (...

journal_title：Pharmaceutical biology

authors： Rahim NS,Lim SM,Mani V,Abdul Majeed AB,Ramasamy K

更新日期：2017-12-01 00:00:00

abstract：:Different extracts from the stem bark of Berberis asiatica L. , a plant traditionally used to hasten the process of wound healing, and the alkaloid fractions derived from the commonly used aqueous extract, were tested for their putative antimicrobial activity against a battery of microorganisms by disk diffusion and a...

journal_title：Pharmaceutical biology

authors： Bhandari DK,Nath G,Ray AB,Tewari PV

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Aquatic organisms (especially fish) require potent defense mechanisms to protect themselves against pathogen invasion and disease formation. The use of immunostimulants in fish culture can prevent the diseases through augmentation of both specific and non-specific immunity. OBJECTIVE:A study was conducted to i...

journal_title：Pharmaceutical biology

authors： Pratheepa V,Ramesh S,Sukumaran N

更新日期：2010-11-01 00:00:00

abstract：CONTEXT:Ageratum conyzoides Linn. (Asteraceae) is an annual herbaceous plant with a long history of traditional medicinal and agricultural uses; it is usually grown in the northeast part of Bangladesh. OBJECTIVE:The ethanol extract of the plant leaves was evaluated for preliminary phytochemical screening with its anti...

journal_title：Pharmaceutical biology

authors： Hossain H,Karmakar UK,Biswas SK,Shahid-Ud-Daula AF,Jahan IA,Adnan T,Chowdhury A

更新日期：2013-07-01 00:00:00

abstract：CONTEXT:Rutin, a flavonoid commonly present in onions, apples and tea, has been suggested to have a variety of pharmacological activities, including immunomodulator, anti-inflammatory and antioxidant activities. OBJECTIVES:The present study was to examine the protective effects of rutin on gastric mucosal damage induc...

journal_title：Pharmaceutical biology

authors： Liu Y,Gou L,Fu X,Li S,Lan N,Yin X

更新日期：2013-07-01 00:00:00

abstract：CONTEXT:Eupatorium triplinerve Vahl (Asteraceae), popularly known as Japana, is widely used in folk medicine, due its analgesic, anticoagulant, antianorexic, antiparasitic, anthelmintic, sedative, antifungal, and antibacterial properties. OBJECTIVE:The present study evaluated the chemical composition and antimicrobial...

journal_title：Pharmaceutical biology

authors： Matos Lopes TR,de Oliveira FR,Malheiros FF,de Andrade MA,Monteiro MC,Baetas Gonçalves AC

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:The extraction method and the crude wound healing effects of sacchachitin from Ganoderma tsugae Murr. (Ganodermataceae) has been cited. However, its purity is still largely limited. OBJECTIVE:An improvement of the fractionation protocol to purify the sacchachitin from Ganoderma lucidum L. (Ganodermataceae) (SG...

journal_title：Pharmaceutical biology

authors： Chuang CM,Wang HE,Chang CH,Peng CC,Ker YB,Lai JE,Chen KC,Peng RY

更新日期：2013-01-01 00:00:00

abstract：CONTEXT:Arecoline is an effective constituent of Areca catechu L. (Arecaceae) with various pharmacological effects. However, investigations also revealed that long use of arecoline could arouse some oral diseases. OBJECTIVE:The present review gathers the fragmented information available in the literature (before 1 Oct...

journal_title：Pharmaceutical biology

authors： Liu YJ,Peng W,Hu MB,Xu M,Wu CJ

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities. OBJECTIVE:The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicit...

journal_title：Pharmaceutical biology

authors： Al-Ashaal HA,El-Sheltawy ST

更新日期：2011-03-01 00:00:00

abstract：CONTEXT:α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). OBJECTIVE:TPN was assessed for its antinociceptive activity in rodents. MATERIALS AND METHODS:The antinociceptive effect of TPN was examined using the acetic acid writhing reflex,...

journal_title：Pharmaceutical biology

authors： Quintans-Júnior LJ,Oliveira MG,Santana MF,Santana MT,Guimarães AG,Siqueira JS,De Sousa DP,Almeida RN

更新日期：2011-06-01 00:00:00

abstract：:Physalis alkekengi L. (Solanaceae) is a popular plant in traditional European and Chinese folk medicine, and it has been reported to have many ethnopharmacological properties including antifungal, anti-cough, anti-inflammatory, analgesic, and febricide activities. Some active components from Physalis species have been...

journal_title：Pharmaceutical biology

authors： Helvaci S,Kökdil G,Kawai M,Duran N,Duran G,Güvenç A

更新日期：2010-02-01 00:00:00

abstract：CONTEXT:Stress-induced changes in the dopaminergic system and subsequent enhancement of oxidative load and behavior are associated with a wide range of central and peripheral nervous disorders. Dopamine acts as a key neurotransmitter in the brain plays an important role in the regulation of motor and limbic functions. ...

journal_title：Pharmaceutical biology

authors： Alghasham A,Rasheed N

更新日期：2014-03-01 00:00:00