Hepatoprotective activity of Glycosmis pentaphylla against paracetamol-induced hepatotoxicity in Swiss albino mice.

abstract：CONTEXT:Aloe has been used for the prevention and cure of various diseases and symptoms including burns, injuries, oedema and pain. OBJECTIVE:This study determines the specific inhibitory activity of matrix metalloproteinase (MMP)-9 induced by the low molecular-weight gel fraction of Aloe vera (L.) Burm.f. (lgfAv) on ...

journal_title：Pharmaceutical biology

authors： Park CH,Son HU,Yoo CY,Lee SH

更新日期：2017-12-01 00:00:00

abstract：:Heliopsis longipes S.F. Blake (Asteraceae: Heliantheae) (chilcuague) is used in Mexican traditional medicine against parasites and to alleviate tooth and muscle pains. Its biocide effect has already been experimentally demonstrated; however, its analgesic action and its action on the nervous system (NS) have not been ...

journal_title：Pharmaceutical biology

authors： Cilia-López VG,Juárez-Flores BI,Aguirre-Rivera JR,Reyes-Agüero JA

更新日期：2010-02-01 00:00:00

abstract：:Breast cancer (BCa) is the most commonly occurring cancer in women, comprising almost one third of all malignancies. Previously we reported that the n-hexane fraction (hSL) of the Siddha herbal medicine, Semecarpus Lehyam, relatively sensitized estrogen receptor-negative (ER(-)) BCa when compared to estrogen receptor-...

journal_title：Pharmaceutical biology

authors： Zhao W,Zhu L,Srinivasan S,Damodaran C,Rohr J

更新日期：2009-09-01 00:00:00

abstract：CONTEXT:Cardioprotective effects of various plants are generally attributed to their antioxidant activity. The whole fruit extract of pomegranate (WFEP), Punica granatum L. (Punicaceae), has a potent antioxidant activity. OBJECTIVE:To investigate cardioprotective effect of WFEP against doxorubicin (Dox)-induced cardio...

journal_title：Pharmaceutical biology

authors： Hassanpour Fard M,Ghule AE,Bodhankar SL,Dikshit M

更新日期：2011-04-01 00:00:00

abstract：CONTEXT:The roots of Phytolacca americana L. (Phytolaccaceae) may be toxic. Despite heated controversy over the toxic compounds of P. americana, especially esculentosides, relevant studies remain scarce. OBJECTIVE:The objective of this study is to screen the toxic fractions and compounds of P. americana, to determine ...

journal_title：Pharmaceutical biology

authors： Yu H,Gong L,Wang X,Wu H,Zhao T,Wang K,Cui X,Chen L

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Bombacaceae is a small family of the order Malvales and contains about 28 genera and 200 species. Members of this family are not only showy ornamentals but they possess significant economical and commercial reputation as well. In addition, various plant parts of several species are widely used as foods and trad...

journal_title：Pharmaceutical biology

authors： Refaat J,Desoky SY,Ramadan MA,Kamel MS

更新日期：2013-01-01 00:00:00

abstract：CONTEXT:Liposomes are increasingly employed to deliver chemotherapeutic agents, antisense oligonucleotides, and genes to various therapeutic targets. OBJECTIVE:The present investigation evaluates the ability of fusogenic pH-sensitive liposomes of rapamycin in increasing its antiproliferative effect on human breast ade...

journal_title：Pharmaceutical biology

authors： Ghanbarzadeh S,Khorrami A,Mohamed Khosroshahi L,Arami S

更新日期：2014-07-01 00:00:00

abstract：CONTEXT:The roots of Alafia barteri Oliver (Apocynaceae), Combretum mucronatum Schumach (Combretaceae) and Capparis thonningii Schum (Capparaceae) are used in Traditional African Medicine to alleviate painful and inflammatory conditions. OBJECTIVE:This study investigated the analgesic and anti-inflammatory effects of ...

journal_title：Pharmaceutical biology

authors： Ishola IO,Agbaje EO,Adeyemi OO,Shukla R

更新日期：2014-09-01 00:00:00

abstract：:Abstract Context: Galbanic acid (GA) is a biologically active sesquiterpene coumarin from Ferula species (Apiaceae). This compound showed various biological properties including anticancer, cancer chemopreventive, anticoagulant, antiviral, and antileishmanial activities. Objectives: This article is a review on the syn...

journal_title：Pharmaceutical biology

authors： Kasaian J,Iranshahy M,Iranshahi M

更新日期：2013-12-13 00:00:00

abstract：CONTEXT:Red ginseng (heat-processed Panax ginseng) is a well-known alternative medicine with pharmacological antidiabetic activity. It exerts pharmacological effects through the transformation of saponin into metabolites by the intestinal microbiota. Given that intestinal conditions and intestinal microflora vary among...

journal_title：Pharmaceutical biology

authors： Jang SH,Park J,Kim SH,Choi KM,Ko ES,Cha JD,Lee YR,Jang H,Jang YS

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Raspberry ketone (RK) is a natural phenolic compound of red raspberry. The dietary intake of RK has been reported to exert anti-obese actions and alter the lipid metabolism in vivo and human studies. OBJECTIVE:To elucidate a possible mechanism for anti-obese actions of RK, the effects of RK on the adipogenic a...

journal_title：Pharmaceutical biology

authors： Park KS

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:Arecoline is an effective constituent of Areca catechu L. (Arecaceae) with various pharmacological effects. However, investigations also revealed that long use of arecoline could arouse some oral diseases. OBJECTIVE:The present review gathers the fragmented information available in the literature (before 1 Oct...

journal_title：Pharmaceutical biology

authors： Liu YJ,Peng W,Hu MB,Xu M,Wu CJ

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Cancer, being a cause of death for major fraction of population worldwide, is one of the most studied diseases and is being investigated for the development of new technologies and more accurate therapies. Still the currently available therapies for cancer have many lacunae which affect the patient's health sev...

journal_title：Pharmaceutical biology

authors： Rai M,Jogee PS,Agarkar G,dos Santos CA

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Investigating potential central nervous system (CNS) activities of Crataegus monogyna Jacq. (Rosaceae), hawthorn, fruit extracts. OBJECTIVE:Evaluating CNS effects and analgesic activities of hawthorn fruit extracts based on the traditional uses of the plant for neurosedative and pain killer actions. MATERIALS...

journal_title：Pharmaceutical biology

authors： Can OD,Ozkay UD,Oztürk N,Oztürk Y

更新日期：2010-08-01 00:00:00

abstract：CONTEXT:The bacterium Pseudomonas syringae pv. syringae (Pss) is a pathogen of many plant species and causes, for example, brown spot disease in bean plants (Phaseolus vulgaris). Pss excretes the syringolins, natural product molecules that act as a virulence factors and inhibit the proteasome of the host plants. OBJEC...

journal_title：Pharmaceutical biology

authors： Opoku-Ansah J,Ibarra-Rivera TR,Pirrung MC,Bachmann AS

更新日期：2012-01-01 00:00:00

abstract：CONTEXT:Herbal therapies are used worldwide to treat health conditions. In Mexico, generations have used them to treat gingivitis, periodontitis, mouth infections, and discoloured teeth. However, few studies have collected scientific evidence on their effects. OBJECTIVE:This study aimed at searching and compiling scie...

journal_title：Pharmaceutical biology

authors： Cruz Martínez C,Diaz Gómez M,Oh MS

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Recent studies have shown compound Danshen dripping pills (CDDP) could improve microcirculation in ischemic/reperfusion injury and other microvascular disorders. The mechanism for CDDP's role in microcirculation is not clear. OBJECTIVE:To explore the protective effects of CDDP on microvascular dysfunction. MA...

journal_title：Pharmaceutical biology

authors： Zhang Y,Zhao J,Ding R,Niu W,He Z,Liang C

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a tropical tree that has many folk uses in various countries. The bark extract is used for the control of the fresh water snails that act as intermediary host of Schistosoma. OBJECTIVE:Study the molluscicidal activity and chemical constituents of seed oil an...

journal_title：Pharmaceutical biology

authors： Dawidar AE,Mortada MM,Raghib HM,Abdel-Mogib M

更新日期：2012-10-01 00:00:00

abstract：CONTEXT:Diabetes mellitus is characterized by oxidative stress, which in turn induces endothelial dysfunction. As a potent antioxidant compound, lycopene might rescue diabetic endothelial dysfunction by reducing oxidative stress. OBJECTIVE:The present study investigated whether lycopene could lower oxidative stress an...

journal_title：Pharmaceutical biology

authors： Zhu J,Wang CG,Xu YG

更新日期：2011-11-01 00:00:00

abstract：CONTEXT: Despite the myriad uses of Annona senegalensis Pers. (Annonaceae) leaves in folklore medicine of Nigeria, the basis is yet to be substantiated by scientific investigations. OBJECTIVES: To investigate the antioxidant (in vitro and in vivo) and drug detoxification potential of aqueous extract of A. senegalensis...

journal_title：Pharmaceutical biology

authors： Ajboye TO,Yakubu MT,Salau AK,Oladiji AT,Akanji MA,Okogun JI

更新日期：2010-12-01 00:00:00

abstract：CONTEXT:Cucurbitacins are a group of triterpenoids that have a cucurbitane skeleton with a wide range of biological activities. OBJECTIVES:This study evaluated the anticancer properties of one cucurbitacin isolated from Cayaponia racemosa Cong. (Cucurbitaceae), 2β,3β,16α,20(R),25-pentahydroxy-22-oxocucurbita-5-en (1),...

journal_title：Pharmaceutical biology

authors： Militão GC,Dantas IN,Ferreira PM,Alves AP,Chaves DC,Monte FJ,Pessoa C,Odorico de Moraes M,Costa-Lotufo LV

更新日期：2012-12-01 00:00:00

abstract：CONTEXT:Stress-induced changes in the dopaminergic system and subsequent enhancement of oxidative load and behavior are associated with a wide range of central and peripheral nervous disorders. Dopamine acts as a key neurotransmitter in the brain plays an important role in the regulation of motor and limbic functions. ...

journal_title：Pharmaceutical biology

authors： Alghasham A,Rasheed N

更新日期：2014-03-01 00:00:00

abstract：CONTEXT:Growing adipose tissue is thought to require adipogenesis, angiogenesis, and extracellular matrix (ECM) remodeling. Close examination of developing adipose tissue microvasculature reveals that angiogenesis often precedes adipogenesis. Since our previous study demonstrated that Ob-X, the anti-angiogenic herbal c...

journal_title：Pharmaceutical biology

authors： Hong Y,Kim MY,Yoon M

更新日期：2011-08-01 00:00:00

abstract：CONTEXT:The incidence and mortality of thrombotic disorders are rapidly increasing throughout the world. Therefore, attempts have been made to develop new anticoagulant and antithrombotic drugs. Our previous studies showed that a novel protein, named Fu-P, had fibrinogenolytic activity and much higher fibrinolytic acti...

journal_title：Pharmaceutical biology

authors： Wu B,Xu J

更新日期：2012-07-01 00:00:00

abstract：CONTEXT:Many plant extracts and compounds are being investigated for their cytotoxicity and hence their medicinal or therapeutic properties. Reports of toxicity studies with limonoid analogs have been sparse and have involved mainly crude extracts. In this study, individual natural limonoids have been isolated and thei...

journal_title：Pharmaceutical biology

authors： Fowles RG,Mootoo BS,Ramsewak RS,Khan A

更新日期：2012-02-01 00:00:00

abstract：CONTEXT:Dicranopteris linearis (Burm.f.) Underw. (Gleicheniaceae) has been scientifically proven to exert various pharmacological activities. Nevertheless, its anti-proliferative potential has not been extensively investigated. OBJECTIVE:To investigate the anti-proliferative potential of D. linearis leaves and determi...

journal_title：Pharmaceutical biology

authors： Baharuddin AA,Roosli RAJ,Zakaria ZA,Md Tohid SF

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Andrographis paniculata (Burm.f.) Nees (Acanthaceae) is widely used in tribal medicine in India and some other countries for multiple clinical applications. It contains andrographolide (AG) (diterpenoid lactone), a major phytomarker which probably accounts for its medicinal properties. OBJECTIVE:This study inv...

journal_title：Pharmaceutical biology

authors： Bera R,Ahmed SK,Sarkar L,Sen T,Karmakar S

更新日期：2014-03-01 00:00:00

abstract：:Context 3,4-Oxo-isopropylidene-shikimic acid (ISA) is an analog of shikimic acid (SA). SA is extracted from the dry fruit of Illicium verum Hook. f. (Magnoliaceae), which has been used for treating stomachaches, skin inflammation and rheumatic pain. Objective To investigate the anti-inflammatory, analgesic and antioxi...

journal_title：Pharmaceutical biology

authors： Sun JY,You CY,Dong K,You HS,Xing JF

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Polygonum multiflorum is known as a medicinal plant. It has been used as a folk medicine which showed antioxidative property. OBJECTIVE:Protective effects of the water extracts (w/v:1/10) from fresh P. multiflorum (WEP) on carbon tetrachloride (CCl(4))-induced liver damage in rats were investigated. MATERIALS...

journal_title：Pharmaceutical biology

authors： Lee BH,Huang YY,Duh PD,Wu SC

更新日期：2012-03-01 00:00:00

abstract：:2-Formyl-1-hydroxyanthraquinone, along with ten other known anthraquinones (1-hydroxy-2-methylanthraquinone, nordamnacanthal, damnacanthal, lucidin-?-methyl ether, rubiadin, rubiadin-1-methyl ether, soranjidiol, morindone, morindone-5-methyl ether and alizarin-1-methyl ether), isolated from the roots of Morinda ellipt...

journal_title：Pharmaceutical biology

authors： Ali AM,Ismail NH,Mackeen MM,Yazan LS,Mohamed SM,Ho AS,Lajis NH

更新日期：2000-01-01 00:00:00