Abstract:
CONTEXT:Aquatic organisms (especially fish) require potent defense mechanisms to protect themselves against pathogen invasion and disease formation. The use of immunostimulants in fish culture can prevent the diseases through augmentation of both specific and non-specific immunity. OBJECTIVE:A study was conducted to investigate the efficacy of different dietary doses of Aegle marmelos (Linn.) Corr. Serr. (Rutaceae) leaf extract for the immune response and the disease resistance of the freshwater fish, Cyprinus carpio Linn. (Cyprinidae) infected by Aeromonas hydrophila Chester (Aeromonadaceae). MATERIALS AND METHODOLOGY:Hematological, specific immune response, non-specific immune response and enzyme assay studies were performed on fish and were scrutinized after 50 days of feeding trial. RESULTS:Fish were challenged with Aeromonas hydrophila at a dose of 1.5 × 10(4) cells/mL through intraperitoneal injection, and the hematological changes, the immune response, the enzyme activity and the disease resistance of Cyprinus carpio against the pathogen were also studied for 20 days at 5-day intervals. DISCUSSION:The results obtained from the study demonstrated that the fish fed with leaf extract of Aegle marmelos incorporated into feed significantly enhanced the red blood cell count, white blood cell count, hemoglobin, phagocytic activity, nitroblue tetrazolium chloride assay, lysozyme, pathogen clearance and enzyme activity compared with the control group. The survivability was higher in the fish which consumed leaf extract-incorporated feed, and the fish group fed with 5 g diet showed highest percentage survival of the fish. CONCLUSION:These results indicate that Aegle marmelos stimulates the immunity and makes the freshwater fish Cyprinus carpio more resistant to Aeromonas hydrophila.
journal_name
Pharm Bioljournal_title
Pharmaceutical biologyauthors
Pratheepa V,Ramesh S,Sukumaran Ndoi
10.3109/13880201003713598subject
Has Abstractpub_date
2010-11-01 00:00:00pages
1224-39issue
11eissn
1388-0209issn
1744-5116journal_volume
48pub_type
杂志文章abstract::Nine species belonging to the genus Lippia - Verbenaceae - are used in Argentine folk medicine. Four of them are known under the trivial name "poleo": L. turbinata Griseb., L. fissicalyx Troncoso, L. integrifolia (Griseb.) Hieron. and L. grisebachiana Mold. Mainly, their leaves are employed as digestive, stomaquique, ...
journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.1076/1388-0209(200004)3821-1FT120
更新日期:2000-01-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.1080/13880209.2020.1750658
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journal_title:Pharmaceutical biology
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doi:10.3109/13880209.2015.1110600
更新日期:2016-09-01 00:00:00
abstract:CONTEXT:Rutin, a flavonoid commonly present in onions, apples and tea, has been suggested to have a variety of pharmacological activities, including immunomodulator, anti-inflammatory and antioxidant activities. OBJECTIVES:The present study was to examine the protective effects of rutin on gastric mucosal damage induc...
journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2013.771375
更新日期:2013-07-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2015.1055635
更新日期:2016-07-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2012.747547
更新日期:2013-05-01 00:00:00
abstract:CONTEXT:Diabetes mellitus is characterized by oxidative stress, which in turn induces endothelial dysfunction. As a potent antioxidant compound, lycopene might rescue diabetic endothelial dysfunction by reducing oxidative stress. OBJECTIVE:The present study investigated whether lycopene could lower oxidative stress an...
journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2011.574707
更新日期:2011-11-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章,评审
doi:10.1080/13880209.2018.1492620
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2013.821664
更新日期:2014-02-01 00:00:00
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journal_title:Pharmaceutical biology
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2010.501084
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2014.892513
更新日期:2014-11-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.1080/13880209.2016.1184690
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journal_title:Pharmaceutical biology
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.3109/13880209.2011.618501
更新日期:2012-04-01 00:00:00
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更新日期:2017-12-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2015.1077463
更新日期:2016-08-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880200903046195
更新日期:2010-01-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2010.523429
更新日期:2011-05-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880200903204000
更新日期:2010-05-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2013.768273
更新日期:2013-07-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2015.1137600
更新日期:2016-09-01 00:00:00
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pub_type: 杂志文章
doi:10.3109/13880209.2013.864685
更新日期:2014-06-01 00:00:00