Ethnopharmacological use of plants by Sisala traditional healers in northwest Ghana.

Abstract:

CONTEXT AND OBJECTIVE:The Sisala traditional healers of northwest Ghana have a rich ethnomedical tradition. The purpose of this study was to collect and analyse data on medicinal plants commonly used by Sisala traditional healers. METHODS:A total of 30 traditional healers were interviewed using a mixture of open- and closed-ended questionnaires after obtaining prior-informed consent. Plant materials of each species of medicinal plant mentioned being used were collected and processed as voucher specimens following standard ethnobotanical methods. RESULTS:The majority (65%) of traditional healers were males, age ≥ 38, and their knowledge about medicinal plants was acquired orally largely from their parents (81.3%). A total of 35 species of plants were reported used to treat 24 diseases. Most (55%) of the plant materials were harvested from the bush and about half (54.8%) of the healers collected plant materials in the morning. Leaf (20%) and root (17.5%) plant materials were most commonly used in the preparation of 27 herbal remedies for treatments. The modes of administration of the herbal remedies were both through internal and external routes. CONCLUSION:The results of this study show that Sisala traditional healers possess rich traditional knowledge about medicinal plants and new therapeutic use claims for 34 medicinal plants used in Ghana and widely within Africa are documented for the first time.

journal_name

Pharm Biol

journal_title

Pharmaceutical biology

authors

Wodah D,Asase A

doi

10.3109/13880209.2011.633920

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

807-15

issue

7

eissn

1388-0209

issn

1744-5116

journal_volume

50

pub_type

杂志文章
  • Baohuoside-I suppresses cell proliferation and migration by up-regulating miR-144 in melanoma.

    abstract:CONTEXT:Baohuoside-I was reported to induce apoptosis in non-small-cell lung cancer and inhibit the growth of multiple myeloma cells. The antitumour potential of baohuoside-I has not been demonstrated in melanoma yet. OBJECTIVE:To investigate the potential antitumour activity of baohuoside-I against melanoma and eluci...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2017.1418391

    authors: Peng YG,Zhang L

    更新日期:2018-12-01 00:00:00

  • Effects of hawthorn seed and pulp extracts on the central nervous system.

    abstract:CONTEXT:Investigating potential central nervous system (CNS) activities of Crataegus monogyna Jacq. (Rosaceae), hawthorn, fruit extracts. OBJECTIVE:Evaluating CNS effects and analgesic activities of hawthorn fruit extracts based on the traditional uses of the plant for neurosedative and pain killer actions. MATERIALS...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880200903305500

    authors: Can OD,Ozkay UD,Oztürk N,Oztürk Y

    更新日期:2010-08-01 00:00:00

  • Anemarsaponin BII inhibits the activity of CYP3A4, 2D6, and 2E1 with human liver microsomes.

    abstract:CONTEXT:Anemarsaponin BII is one of the most active saponins isolated from Anemarrhena asphodeloides Bunge (Asparagaceae), a commonly used Chinese traditional paediatric medicine. OBJECTIVE:This study investigates the effects of anemarsaponin BII on the activity of CYP450s to provide more guidance for the clinical use...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2020.1835996

    authors: Wang M,Jiang W,Zhou J,Xue X,Yin C

    更新日期:2020-12-01 00:00:00

  • Microscopical discrimination of the subterranean organs of medicinally used plants of the Cichorieae and their relatives.

    abstract:CONTEXT:Light microscopy is in most cases a quick method for the identification and discrimination of medicinally used plant drugs; moreover, this technique is very inexpensive. Reliable descriptions of the anatomy of plants and their adulterations are prerequisites for necessary purity controls. OBJECTIVE:The anatomy...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2010.548390

    authors: Fritz E,Saukel J

    更新日期:2011-08-01 00:00:00

  • Antimicrobial effect of the extracts from Hypericum perforatum against oral bacteria and biofilm formation.

    abstract:CONTEXT:One traditional medicines, Hypericum perforatum L. (Hypericaceae), possesses several beneficial effects against depression, ulcers, dyspepsia, abdominal pains, burns, bacterial infections, migraine headaches, and sciatica. OBJECTIVE:The present study investigates the antimicrobial activity of the ethanol extra...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2015.1102948

    authors: Süntar I,Oyardı O,Akkol EK,Ozçelik B

    更新日期:2016-01-01 00:00:00

  • Neuroprotective and antioxidant potential of terpenoid fraction from Hygrophila auriculata against transient global cerebral ischemia in rats.

    abstract:CONTEXT:The plant Hygrophila auriculata (K. Schum) Heine. (Acanthaceae) is widely used in the Indian System of Medicine as "Rasayana" for treating brain and liver diseases. OBJECTIVES:The present study evaluated the in vivo antioxidant and neuroprotective effect of aterpenoid rich fraction (TF) from Hygrophila auricul...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2012.716851

    authors: Kanhere R,Anjana A,Anbu J,Sumithra M,K F H NA

    更新日期:2013-02-01 00:00:00

  • Immunomodulatory effect of Aegle marmelos leaf extract on freshwater fish Cyprinus carpio infected by bacterial pathogen Aeromonas hydrophila.

    abstract:CONTEXT:Aquatic organisms (especially fish) require potent defense mechanisms to protect themselves against pathogen invasion and disease formation. The use of immunostimulants in fish culture can prevent the diseases through augmentation of both specific and non-specific immunity. OBJECTIVE:A study was conducted to i...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880201003713598

    authors: Pratheepa V,Ramesh S,Sukumaran N

    更新日期:2010-11-01 00:00:00

  • Effect of macronutrient deficiency on withanolides content in the roots of Withania somnifera and its correlationship with molybdenum content.

    abstract:CONTEXT:The content of withanolides in the roots of Withania somnifera (L.) Dunal (Solanaceae) is important for therapeutic application. Earlier studies have shown that the deficiency of macro- and micronutrients affects the growth of W. somnifera. Therefore, we examined the effect of these deficiencies on the withanol...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.931439

    authors: Devkar ST,Suryapujary SM,Jagtap SD,Katyare SS,Hegde MV

    更新日期:2015-04-01 00:00:00

  • Effects of intragastric administration of five oyster components on endurance exercise performance in mice.

    abstract:CONTEXT:Oysters [Crassostrea plicatula Gmelin (Ostreidae)] are widely used for food in coastal areas. It is reported to have several qualities such as improving sexual and immune function. They has been approved by Chinese Ministry of Health as a functional food. OBJECTIVE:The effects of five types of oyster component...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.866966

    authors: Hao G,Zhang C,Cao W,Hao J

    更新日期:2014-06-01 00:00:00

  • Application of vancomycin in patients with varying renal function, especially those with augmented renal clearance.

    abstract:CONTEXT:Augmented renal clearance (ARC) refers to enhanced renal elimination of circulating solute, and has attracted wide attention in recent years. OBJECTIVE:This study evaluates the effects of ARC on serum vancomycin concentration in patients administered vancomycin. MATERIALS AND METHODS:This was a retrospective ...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2016.1183684

    authors: Chu Y,Luo Y,Qu L,Zhao C,Jiang M

    更新日期:2016-12-01 00:00:00

  • Assessment of in vitro. Antifungal Activities of Various Extracts of Indigenous Bahraini Medicinal Plants.

    abstract::The in vitro. antifungal activity of the aqueous, ethanol, chloroform, petroleum ether, and residue extracts from 10 indigenous Bahraini plants used in folk medicine for the treatment of various diseases is reported. Extract efficacy was evaluated using the agar well diffusion assay against four filamentous fungi and ...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880200590951766

    authors: Mandeel Q,Taha A

    更新日期:2005-01-01 00:00:00

  • Astragaloside IV attenuates inflammatory reaction via activating immune function of regulatory T-cells inhibited by HMGB1 in mice.

    abstract:CONTEXT:High-mobility group box 1 (HMGB1) protein is a highly abundant protein that can promote the pathogenesis of inflammatory. Some experiments have demonstrated a vital role for HMGB1 to modulate the immune function of regulatory T-cells (Tregs). Astragaloside IV (AST IV), an extract from Astragalus membranaceus Mo...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2016.1216133

    authors: Li J,Huang L,Wang S,Yao Y,Zhang Z

    更新日期:2016-12-01 00:00:00

  • Involvement of GABAergic system in regulation of the anxiolytic- and antidepressant-like effects of Scrophularia striata extract in rats.

    abstract:CONTEXT:Neuropsychiatric disorders, like anxiety and depression, are global problems for clinical researchers in neurology. Recently, some authors have shown neuroprotective and anti-inflammatory effects of Scrophularia striata Boiss (Scrophulariaceae) extract in rodents. OBJECTIVE:The purpose of the current study was...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2012.749924

    authors: Kosari-Nasab M,Babri S,Fatehi-Gharehlar L,Doosti MH,Pakzad S

    更新日期:2013-05-01 00:00:00

  • Modulation of cyclophosphamide-induced early lung injury by allicin.

    abstract:CONTEXT:Cyclophosphamide (CP) causes lung injury in rats through its ability to generate free radicals with subsequent epithelial and endothelial cell damage. OBJECTIVE:This study was conducted to assess whether allicin can ameliorate CP-induced early lung injury in rats. MATERIALS AND METHODS:Male Sprague Dawely rat...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.766895

    authors: Ashry NA,Gameil NM,Suddek GM

    更新日期:2013-06-01 00:00:00

  • Vasorelaxant mode of action of dichloromethane-soluble extract from Agastache mexicana and its main bioactive compounds.

    abstract:CONTEXT:Agastache mexicana (Kunth) Lint & Epling (Lamiaceae) is a plant used in Mexican traditional medicine for the treatment of hypertension, anxiety and so on. OBJECTIVE:To determine the vasorelaxant effect and functional mode of action of dichloromethane-soluble extract from A. mexicana (DEAm) and isolate the cons...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2016.1184690

    authors: Flores-Flores A,Hernández-Abreu O,Rios MY,León-Rivera I,Aguilar-Guadarrama B,Castillo-España P,Perea-Arango I,Estrada-Soto S

    更新日期:2016-12-01 00:00:00

  • Beneficial effects of melatonin on serum nitric oxide, homocysteine, and ADMA levels in fructose-fed rats.

    abstract:CONTEXT:Melatonin, a pineal hormone and a potent antioxidant, has important roles in metabolic regulation. OBJECTIVE:This study investigated serum asymmetric dimethylarginine (ADMA), homocysteine (Hcy), nitric oxide (NO) levels, known to be reliable markers of cardiovascular diseases, and determined possible protectiv...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.957782

    authors: Kantar Ş,Türközkan N,Bircan FS,Paşaoğlu ÖT

    更新日期:2015-07-01 00:00:00

  • Changes in bioactive components related to the harvest time from the spicas of Prunella vulgaris.

    abstract:CONTEXT:Prunella vulgaris L. (Labiatae) is a perennial plant common in China and Europe and is rich in rosmarinic acid (RA), ursolic acid (UA), and oleanolic acid (OA). The dried spica of P. vulgaris has been used as traditional medicine in China for over a hundred years. To our best knowledge, no study has been conduc...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2012.658477

    authors: Chen Y,Guo Q,Zhu Z,Zhang L

    更新日期:2012-09-01 00:00:00

  • Cytotoxic effects of Eryngium kotschyi and Eryngium maritimum on Hep2, HepG2, Vero and U138 MG cell lines.

    abstract:CONTEXT:Eryngium maritimum L. and the endemic Eryngium kotschyi Boiss. of the Apiaceae family are used for antiinflammatory, antivenom, antinociceptive and diuretic purposes in folk medicine in Turkey. OBJECTIVE:This study investigated the cytotoxic effects of the plant extracts belonging to Eryngium L. genus on vario...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.803208

    authors: Yurdakök B,Baydan E

    更新日期:2013-12-01 00:00:00

  • Effects of naringenin on the pharmacokinetics of tofacitinib in rats.

    abstract::Context: Naringenin and tofacitinib are often used together for treatment of rheumatoid arthritis in Chinese clinics.Objective: This experiment investigates the effect of naringenin on the pharmacokinetics of tofacitinib in rats.Materials and methods: Twelve Sprague-Dawley rats were randomly divided into two groups (e...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2020.1738504

    authors: Wang B,Shen J,Zhou Q,Meng D,He Y,Chen F,Wang S,Ji W

    更新日期:2020-12-01 00:00:00

  • Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress.

    abstract:CONTEXT:Virgin coconut oil (VCO) has been reported to possess antioxidative, anti-inflammatory and anti-stress properties. OBJECTIVE:Capitalizing on these therapeutic effects, this study investigated for the first time the potential of VCO on memory improvement in vivo. MATERIALS AND METHODS:Thirty male Wistar rats (...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2017.1280688

    authors: Rahim NS,Lim SM,Mani V,Abdul Majeed AB,Ramasamy K

    更新日期:2017-12-01 00:00:00

  • Neuroprotective effect of the marine macroalga Gelidiella acerosa: identification of active compounds through bioactivity-guided fractionation.

    abstract::Context Gelidiella acerosa (Forsskål) Feldmann & G. Hamel (Rhodophyta-Gelidiales) is a marine red macroalga. Our previous work found that a benzene extract of G. acerosa possesses noticeable neuroprotective activity, when evaluated through in vitro and in vivo systems. Objective Bioactive-guided fractionation and iden...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2016.1145700

    authors: Syad AN,Rajamohamed BS,Shunmugaiah KP,Kasi PD

    更新日期:2016-10-01 00:00:00

  • Expression and bioactivity analysis of staphylococcal enterotoxin G and staphylococcal enterotoxin I.

    abstract:CONTEXT:The filtrate of Staphylococcus aureus culture, named staphylococcal enterotoxin C injection, has been used for 10 years in China. SEC2 has been claimed to be the only staphylococcal enterotoxins (SEs) without certifiable evidence. OBJECTIVES:To present an efficient procedure for the expression and purification...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.804845

    authors: Chen B,Akash MS,Rehman K,Sun H,Chen S

    更新日期:2014-01-01 00:00:00

  • Anticoccidial effect of Fructus Meliae toosendan extract against Eimeria tenella.

    abstract:CONTEXT:Fructus Meliae toosendan extracts (FMTE) have a good therapeutic effect on coccidiosis, but there is no relevant research on its prophylactic effect on coccidiosis. OBJECTIVE:This study comprehensively evaluates the anticoccidial effect of FMTE. MATERIALS AND METHODS:In vitro, the unsporulated oocysts were tr...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2020.1784234

    authors: Yong T,Chen M,Li Y,Song X,Huang Y,Chen Y,Jia R,Zou Y,Li L,Yin L,He C,Lv C,Liang X,Ye G,Yin Z

    更新日期:2020-12-01 00:00:00

  • Hepatoprotection of emodin and Polygonum multiflorum against CCl(4)-induced liver injury.

    abstract:CONTEXT:Polygonum multiflorum is known as a medicinal plant. It has been used as a folk medicine which showed antioxidative property. OBJECTIVE:Protective effects of the water extracts (w/v:1/10) from fresh P. multiflorum (WEP) on carbon tetrachloride (CCl(4))-induced liver damage in rats were investigated. MATERIALS...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2011.604335

    authors: Lee BH,Huang YY,Duh PD,Wu SC

    更新日期:2012-03-01 00:00:00

  • Huperzine alkaloids from Australasian and southeast Asian Huperzia.

    abstract:CONTEXT:The pharmaceutical alkaloid huperzine A (HupA), currently used in herbal supplements and medicines worldwide, is predominantly sourced from the Chinese lycopod Huperzia serrata (Thunb. ex Murray) Trev. (Lycopodiaceae), which on average contains only 0.08 mg HupA g(-1) dry weight, and is experiencing a rapid dec...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2010.485619

    authors: Lim WH,Goodger JQ,Field AR,Holtum JA,Woodrow IE

    更新日期:2010-09-01 00:00:00

  • Evaluation of anti-inflammatory effect of Withania somnifera root on collagen-induced arthritis in rats.

    abstract:CONTEXT:Withania somnifera (Linn.) Dunal (Solanaceae) has long been used as an herb in Ayurvedic and indigenous medicine and has received intense attention in recent years for its chemopreventive properties. OBJECTIVE:The present study focuses on the effect of W. somnifera root powder on the behavioral and radiologica...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.835325

    authors: Gupta A,Singh S

    更新日期:2014-03-01 00:00:00

  • Molluscicidal activity of Balanites aegyptiaca against Monacha cartusiana.

    abstract:CONTEXT:Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a tropical tree that has many folk uses in various countries. The bark extract is used for the control of the fresh water snails that act as intermediary host of Schistosoma. OBJECTIVE:Study the molluscicidal activity and chemical constituents of seed oil an...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2012.674950

    authors: Dawidar AE,Mortada MM,Raghib HM,Abdel-Mogib M

    更新日期:2012-10-01 00:00:00

  • Geraniinic acid derivative from the leaves of Phyllanthus reticulatus.

    abstract::Chemical constituents as well as cytotoxic and insecticidal activity of the crude methanol extract from the leaves of Phyllanthus reticulatus Poir. (Euphorbiaceae) were investigated. (5R*,6R*)-4,6-Dimethoxycarbonyl-5-[2',3',4'-trihydroxy-6'-(methoxycarbonyl) phenyl]-5,6-dihydro-2H-pyran-2-one (1) along with 3,4,3'-tri...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880200903273898

    authors: Pojchaijongdee N,Sotanaphun U,Limsirichaikul S,Poobrasert O

    更新日期:2010-07-01 00:00:00

  • Effect of lycopene on oxidative stress induced during D-galactosamine/lipopolysaccharide-sensitized liver injury in rats.

    abstract:CONTEXT:Lycopene is a phytonutrient under considerable investigation for its antioxidant benefits in treating diseases like cancer, cardiovascular diseases, osteoporosis and diabetes. OBJECTIVE:This study explores the effect of lycopene against oxidative damage during experimental hepatitis, induced by D-galactosamine...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.803579

    authors: Sheik Abdulazeez S,Thiruvengadam D

    更新日期:2013-12-01 00:00:00

  • Griflola frondosa (GF) produces significant antidepressant effects involving AMPA receptor activation in mice.

    abstract:CONTEXT:Griflola frondosa (Fr) S.F. Gray (Meripilaceae) (GF) is a medical mushroom, and its regulation of the immune system is of interest for the treatment of mood disorders. α-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors are the central mediator for the treatment of depression. OBJECTIVE:This...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2016.1235590

    authors: Bao H,Ran P,Sun L,Hu W,Li H,Xiao C,Zhu K,Du J

    更新日期:2017-12-01 00:00:00