Microscopical discrimination of the subterranean organs of medicinally used plants of the Cichorieae and their relatives.

abstract：CONTEXT:Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant. Its roots are used as the famous traditional Chinese medicine Huang-Qin, which is recorded in Chinese Pharmacopoeia, European Pharmacopoeia, and British Pharmacopoeia. OBJECTIVE:This review comprehensively summarizes research progress in ...

journal_title：Pharmaceutical biology

authors： Wang ZL,Wang S,Kuang Y,Hu ZM,Qiao X,Ye M

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Cucurbitacins are a group of triterpenoids that have a cucurbitane skeleton with a wide range of biological activities. OBJECTIVES:This study evaluated the anticancer properties of one cucurbitacin isolated from Cayaponia racemosa Cong. (Cucurbitaceae), 2β,3β,16α,20(R),25-pentahydroxy-22-oxocucurbita-5-en (1),...

journal_title：Pharmaceutical biology

authors： Militão GC,Dantas IN,Ferreira PM,Alves AP,Chaves DC,Monte FJ,Pessoa C,Odorico de Moraes M,Costa-Lotufo LV

更新日期：2012-12-01 00:00:00

abstract：CONTEXT:Termitomyces clypeatus (Lyophyllaceae) is a filamentous edible mushroom, having ethnomedicinal uses. However, information about the antioxidant, anticancer and antitumour properties of this mushroom remains to be elucidated. OBJECTIVE:The study examines the in vitro antioxidant, anticancer and in vivo antitumo...

journal_title：Pharmaceutical biology

authors： Mondal A,Banerjee D,Majumder R,Maity TK,Khowala S

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Plants and most of the plant-derived compounds have long been known for their potential pharmaceutical effects. They are well known to play an important role in the treatment of several diseases from diabetes to various types of cancers. Today most of the clinically effective pharmaceuticals are developed from ...

journal_title：Pharmaceutical biology

authors： Koc S,Isgor BS,Isgor YG,Shomali Moghaddam N,Yildirim O

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). OBJECTIVE:TPN was assessed for its antinociceptive activity in rodents. MATERIALS AND METHODS:The antinociceptive effect of TPN was examined using the acetic acid writhing reflex,...

journal_title：Pharmaceutical biology

authors： Quintans-Júnior LJ,Oliveira MG,Santana MF,Santana MT,Guimarães AG,Siqueira JS,De Sousa DP,Almeida RN

更新日期：2011-06-01 00:00:00

abstract：CONTEXT:Vernonia amygdalina Del. (VA; Asteraceae or Compositae) is a small tree growing throughout tropical Africa. It is widely used for food and medicinal purposes by local people. It was reported that it had several qualities, including anticancer activity. OBJECTIVE:A sesquiterpene lactone, vernodalinol, was isola...

journal_title：Pharmaceutical biology

authors： Luo X,Jiang Y,Fronczek FR,Lin C,Izevbigie EB,Lee KS

更新日期：2011-05-01 00:00:00

abstract：CONTEXT:Diabetic nephropathy is one of the important microvascular complications of diabetes; however, the main problem remains is the control of progression of nephropathy in diabetes. Chebulic acid was selected, as tannins from Terminalia chebula are used as antidiabetic, renoprotective, antioxidant, hypotensive and ...

journal_title：Pharmaceutical biology

authors： Silawat N,Gupta VB

更新日期：2013-01-01 00:00:00

abstract：CONTEXT:Neuropsychiatric disorders, like anxiety and depression, are global problems for clinical researchers in neurology. Recently, some authors have shown neuroprotective and anti-inflammatory effects of Scrophularia striata Boiss (Scrophulariaceae) extract in rodents. OBJECTIVE:The purpose of the current study was...

journal_title：Pharmaceutical biology

authors： Kosari-Nasab M,Babri S,Fatehi-Gharehlar L,Doosti MH,Pakzad S

更新日期：2013-05-01 00:00:00

abstract：CONTEXT:Ginger has been used commonly in the traditional system of medicine for the treatment of respiratory disorders. OBJECTIVE:The present study investigates the immunosuppressive activity of ginger by using the mouse model of ovalbumin-induced allergic asthma. MATERIALS AND METHODS:Treatment with ethanol extract ...

journal_title：Pharmaceutical biology

authors： Khan AM,Shahzad M,Raza Asim MB,Imran M,Shabbir A

更新日期：2015-03-01 00:00:00

abstract：CONTEXT:Amla [Emblica officinalis Gaertn. (Euphorbiaceae)], a major constituent of several herbal formulations, is a well-known hepatoprotectant. Despite its extensive use, mechanistic understanding of its antioxidant action is rather limited. OBJECTIVE:In the current study, we investigated the effects of E. officinal...

journal_title：Pharmaceutical biology

authors： Shivananjappa MM,Joshi MK

更新日期：2012-04-01 00:00:00

abstract：CONTEXT:1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines. OBJECTIVE:To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of 1 ...

journal_title：Pharmaceutical biology

authors： Sun J,Jiang T,Xu W,Feng Z,Quan X,Leng P,Sun W,Zhao J,Jing F,Li J

更新日期：2019-12-01 00:00:00

abstract：CONTEXT:Salvicine is a pharmacologically active derivative from Chinese medicinal plant Salvia prionitis Hance (Labiatae). It has been reported that salvicine inactivates β1 integrin and inhibits integrin-mediated cell adhesion to fibronectin. Given the emerging correlation between integrins and angiogenesis, we propos...

journal_title：Pharmaceutical biology

authors： Zhang Y,Wang L,Chen Y,Qing C

更新日期：2013-08-01 00:00:00

abstract：:Abstract Context: Galbanic acid (GA) is a biologically active sesquiterpene coumarin from Ferula species (Apiaceae). This compound showed various biological properties including anticancer, cancer chemopreventive, anticoagulant, antiviral, and antileishmanial activities. Objectives: This article is a review on the syn...

journal_title：Pharmaceutical biology

authors： Kasaian J,Iranshahy M,Iranshahi M

更新日期：2013-12-13 00:00:00

abstract：:Several drugs of herbal origin are known to possess anxiolytic and antidepressant effects. In a recent study, we showed that extracts from Euphorbia hirta L. (Euphorbiaceae) (Eh) demonstrated anxiolytic effects in rats subjected to chronic immobilization stress (CIS) but not in rats that underwent forced swim stress (...

journal_title：Pharmaceutical biology

authors： Anuradha H,Srikumar BN,Deepti N,Shankaranarayana Rao BS,Lakshmana M

更新日期：2010-05-01 00:00:00

abstract：CONTEXT:A previous study demonstrated that the chloroform extract of Salvia connivens Epling (Lamiaceae) has anti-inflammatory activity. OBJECTIVE:Identification of the active components in the dicholorometane extract (DESC), and, standardization of the extract based in ursolic acid. MATERIAL AND METHODS:DESC was pre...

journal_title：Pharmaceutical biology

authors： González-Chávez MM,Ramos-Velázquez CS,Serrano-Vega R,Pérez-González C,Sánchez-Mendoza E,Pérez-Gutiérrez S

更新日期：2017-12-01 00:00:00

abstract：:Nine species belonging to the genus Lippia - Verbenaceae - are used in Argentine folk medicine. Four of them are known under the trivial name "poleo": L. turbinata Griseb., L. fissicalyx Troncoso, L. integrifolia (Griseb.) Hieron. and L. grisebachiana Mold. Mainly, their leaves are employed as digestive, stomaquique, ...

journal_title：Pharmaceutical biology

authors： Bassols GB,Gurni AA

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Vicenin-1, a flavonol glycoside, has potent platelet aggregation inhibition, antioxidant, radioprotectants and anti-inflammatory activities. OBJECTIVE:To establish a rapid, simple, precise and sensitive high-performance liquid chromatography (HPLC) method for determination of vicenin-1 in rat plasma, and to in...

journal_title：Pharmaceutical biology

authors： Kandhare AD,Bodhankar SL,Mohan V,Thakurdesai PA

更新日期：2016-11-01 00:00:00

abstract：:Context 3,4-Oxo-isopropylidene-shikimic acid (ISA) is an analog of shikimic acid (SA). SA is extracted from the dry fruit of Illicium verum Hook. f. (Magnoliaceae), which has been used for treating stomachaches, skin inflammation and rheumatic pain. Objective To investigate the anti-inflammatory, analgesic and antioxi...

journal_title：Pharmaceutical biology

authors： Sun JY,You CY,Dong K,You HS,Xing JF

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Several plant-derived natural products have been used in clinical phase for applications in neurological, cardiovascular, and inflammatory diseases. Arbutus andrachne L. (Ericacea) is an evergreen shrub native to the Mediterranean region. Traditionally, the fruits and leaves of Arbutus tree are well known and u...

journal_title：Pharmaceutical biology

authors： Abidi E,Habib J,Yassine A,Chahine N,Mahjoub T,Elkak A

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Naringin is a bioflavonoid derivative and is predominantly found in Citrus paradisi Macf., Citrus sinensis (Linn.) Osbeck, Citrus unshiu Marc., Citrus reticulata Blanco cv. Nobilis, Citrus tachibana (Makino) Tanaka, Citrus junos Sieb. ex Tanaka (Rutaceae), and related citrus species. It has anti-inflammatory ef...

journal_title：Pharmaceutical biology

authors： Si-Si W,Liao L,Ling Z,Yun-Xia Y

更新日期：2011-08-01 00:00:00

abstract：CONTEXT:Bombacaceae is a small family of the order Malvales and contains about 28 genera and 200 species. Members of this family are not only showy ornamentals but they possess significant economical and commercial reputation as well. In addition, various plant parts of several species are widely used as foods and trad...

journal_title：Pharmaceutical biology

authors： Refaat J,Desoky SY,Ramadan MA,Kamel MS

更新日期：2013-01-01 00:00:00

abstract：:Abstract Context: Diabetes mellitus (DM) type 2 is a chronic disease characterized by hyperglycemia and insulin resistance. Oxidative stress participates in development and progression of DM, in which changes of superoxide dismutase (SOD) and catalase (CAT) were noted in DM mice. Berberine has been widely used as an a...

journal_title：Pharmaceutical biology

authors： Chatuphonprasert W,Lao-Ong T,Jarukamjorn K

更新日期：2013-11-05 00:00:00

abstract：CONTEXT:Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a tropical tree that has many folk uses in various countries. The bark extract is used for the control of the fresh water snails that act as intermediary host of Schistosoma. OBJECTIVE:Study the molluscicidal activity and chemical constituents of seed oil an...

journal_title：Pharmaceutical biology

authors： Dawidar AE,Mortada MM,Raghib HM,Abdel-Mogib M

更新日期：2012-10-01 00:00:00

abstract：CONTEXT:Schizophrenia is a chronic disabling psychiatric disorder affecting 1% of the population worldwide. Due to the adverse effects of available antipsychotic medications, recent investigations have focused on the search for well-tolerated, safe molecules from natural resources to control the severity and progressio...

journal_title：Pharmaceutical biology

authors： Chatterjee M,Verma R,Kumari R,Singh S,Verma AK,Dwivedi AK,Palit G

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:In traditional medicine propolis is widely used for the treatment of various ailments including ulcer and wound healing. The phytochemical screening of Indian propolis indicates the presence of biologically active ingredients in appreciable amounts. In the absence of systematic evaluation of wound healing prope...

journal_title：Pharmaceutical biology

authors： Iyyam Pillai S,Palsamy P,Subramanian S,Kandaswamy M

更新日期：2010-11-01 00:00:00

abstract：CONTEXT:Salsola imbricata Forssk. (Chenopodiaceae) has folkloric repute for the treatment of various gastrointestinal and respiratory ailments. OBJECTIVE:The present study investigates spasmolytic and bronchorelaxant effects of S. imbricata. MATERIALS AND METHODS:The crude aqueous-ethanol extract of the aerial parts ...

journal_title：Pharmaceutical biology

authors： Aslam N,Janbaz KH

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Medical therapies for alcohol-induced liver disease are often difficult to handle and limited in efficacy. OBJECTIVE:In an attempt to find natural therapeutics, here, we investigate the preventive effect of persimmon vinegar (PV) and its fractions against alcohol-induced hepatic injury, in addition to the unde...

journal_title：Pharmaceutical biology

authors： Lee HM,Park MY,Kim J,Shin JH,Park KS,Kwon O

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Propranolol, atenolol, and ICI118,551 are non-selective β-adrenergic receptor (AR), β1-AR, and β2-AR antagonists, respectively. OBJECTIVE:We investigated the efficacy of propranolol, atenolol, and ICI118,551 on proliferation, migration, and invasion of non-stimulated breast (MCF7), colon (HT-29), and hepatocel...

journal_title：Pharmaceutical biology

authors： Işeri OD,Sahin FI,Terzi YK,Yurtcu E,Erdem SR,Sarialioglu F

更新日期：2014-11-01 00:00:00

abstract：CONTEXT:Alpinia oxyphylla Miquel (Zingiberaceae) is a traditional Chinese herbal medicine widely used for the treatment of intestinal disorders, urosis and diuresis. However, information about antioxidant and cytotoxic properties of its fruits remains to be elucidated. OBJECTIVE:The ethanol crude extract (CE) and its ...

journal_title：Pharmaceutical biology

authors： Wang CZ,Yuan HH,Bao XL,Lan MB

更新日期：2013-11-01 00:00:00

abstract：:Context Shengmai injection (SMI) is a patented Chinese medicine originated from the ancient Chinese herbal compound Shengmai san, which is used extensively for the treatment of cardiovascular and cerebrovascular disease in the clinic. Objective To determine the neuroprotective effect of SMI, we investigated the effect...

journal_title：Pharmaceutical biology

authors： Yang H,Li L,Zhou K,Wang Y,Guan T,Chai C,Kou J,Yu B,Yan Y

更新日期：2016-10-01 00:00:00