Restoration of acetylcholinesterase activity by Euphorbia hirta in discrete brain regions of chronically stressed rats.

abstract：:Abstract Context: Diabetes mellitus (DM) type 2 is a chronic disease characterized by hyperglycemia and insulin resistance. Oxidative stress participates in development and progression of DM, in which changes of superoxide dismutase (SOD) and catalase (CAT) were noted in DM mice. Berberine has been widely used as an a...

journal_title：Pharmaceutical biology

authors： Chatuphonprasert W,Lao-Ong T,Jarukamjorn K

更新日期：2013-11-05 00:00:00

abstract：CONTEXT:Cataract is the clouding of eye lens which causes impairment in vision and accounts for the leading factor of global blindness. Functional food-based prevention of cataract finds application in vision research because of its availability and easy access to all classes of the society. Cassia tora Linn. (Caesalpi...

journal_title：Pharmaceutical biology

authors： Sreelakshmi V,Abraham A

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Cyclophosphamide (CP) causes lung injury in rats through its ability to generate free radicals with subsequent epithelial and endothelial cell damage. OBJECTIVE:This study was conducted to assess whether allicin can ameliorate CP-induced early lung injury in rats. MATERIALS AND METHODS:Male Sprague Dawely rat...

journal_title：Pharmaceutical biology

authors： Ashry NA,Gameil NM,Suddek GM

更新日期：2013-06-01 00:00:00

abstract：CONTEXT:Millettia barteri (Benth.) Dunn (Fabaceae) is an African medicinal plant used in folk medicine to treat many diseases. This species, as well as other Mellettia species, has been of interest to researchers because of their wide range of traditional uses. OBJECTIVE:Phytochemical, antimicrobial and 2,2-diphenyl-1...

journal_title：Pharmaceutical biology

authors： Havyarimana L,Ndendoung ST,Tamokou Jde D,Atchadé Ade T,Tanyi JM

更新日期：2012-02-01 00:00:00

abstract：:Abstract Context: Galbanic acid (GA) is a biologically active sesquiterpene coumarin from Ferula species (Apiaceae). This compound showed various biological properties including anticancer, cancer chemopreventive, anticoagulant, antiviral, and antileishmanial activities. Objectives: This article is a review on the syn...

journal_title：Pharmaceutical biology

authors： Kasaian J,Iranshahy M,Iranshahi M

更新日期：2013-12-13 00:00:00

abstract：CONTEXT:Carissa edulis Vahl (Apocynaceae) is used in Nigerian folk medicine to manage a plethora of diseases including epilepsy, cancer, and inflammation; its efficacy is widely acclaimed among communities of northern Nigeria. OBJECTIVE:This study establishes anticonvulsant activities of aqueous fraction of ethanol ro...

journal_title：Pharmaceutical biology

authors： Ya'u J,Yaro AH,Malami S,Musa MA,Abubakar A,Yahaya SM,Chindo BA,Anuka JA,Hussaini IM

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Plants and most of the plant-derived compounds have long been known for their potential pharmaceutical effects. They are well known to play an important role in the treatment of several diseases from diabetes to various types of cancers. Today most of the clinically effective pharmaceuticals are developed from ...

journal_title：Pharmaceutical biology

authors： Koc S,Isgor BS,Isgor YG,Shomali Moghaddam N,Yildirim O

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:Agastache mexicana (Kunth) Lint & Epling (Lamiaceae) is a plant used in Mexican traditional medicine for the treatment of hypertension, anxiety and so on. OBJECTIVE:To determine the vasorelaxant effect and functional mode of action of dichloromethane-soluble extract from A. mexicana (DEAm) and isolate the cons...

journal_title：Pharmaceutical biology

authors： Flores-Flores A,Hernández-Abreu O,Rios MY,León-Rivera I,Aguilar-Guadarrama B,Castillo-España P,Perea-Arango I,Estrada-Soto S

更新日期：2016-12-01 00:00:00

abstract：:Breast cancer (BCa) is the most commonly occurring cancer in women, comprising almost one third of all malignancies. Previously we reported that the n-hexane fraction (hSL) of the Siddha herbal medicine, Semecarpus Lehyam, relatively sensitized estrogen receptor-negative (ER(-)) BCa when compared to estrogen receptor-...

journal_title：Pharmaceutical biology

authors： Zhao W,Zhu L,Srinivasan S,Damodaran C,Rohr J

更新日期：2009-09-01 00:00:00

abstract：UNLABELLED:Abstract Context: Solute carrier transporters (SLCs) are membrane proteins responsible for cellular influx of various substances including many pharmaceutical agents; therefore, they largely impact on drug disposition and elimination in body. Punica granatum Linnaeus (Lythraceae), pomegranate, is a fruit wit...

journal_title：Pharmaceutical biology

authors： Li Z,Wang K,Zheng J,Cheung FS,Chan T,Zhu L,Zhou F

更新日期：2014-12-01 00:00:00

abstract：:Essential oil compositions and antioxidant potentials of fourteen ethanol (75%) root extracts prepared from twelve taxa of the genus Paeonia (Paeoniaceae), including P. arietina Anders., P. daurica Andrews, P. xkayae N. Ozhatay, P. kesrouanensis Thiéb., P. mascula (L.) Miller subsp. arasicola G. Kaynak, ö. Yilmaz & R....

journal_title：Pharmaceutical biology

authors： Orhan I,Demirci B,Omar I,Siddiqui H,Kaya E,Choudhary MI,Ecevit-Genç G,Ozhatay N,Sener B,Başer KH

更新日期：2010-01-01 00:00:00

abstract：CONTEXT:Peripheral axon injury and degeneration are often mediated by oxidative stress and inflammation. The hydroalcoholic extract of the red propolis (HERP) has attracted great attention because of its antioxidant and anti-inflammatory activities. OBJECTIVE:The objective of this work is to study the effect of HERP o...

journal_title：Pharmaceutical biology

authors： Barbosa RA,Nunes TL,Nunes TL,da Paixão AO,Belo Neto R,Moura S,Albuquerque Junior RL,Cândido EA,Padilha FF,Quintans-Júnior LJ,Gomes MZ,Cardoso JC

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Panax ginseng C. A. Mey (Araliaceae) has been widely used in clinic for treatment of cardiovascular diseases in China. Ginsenoside Rb3 is the main chemical component of Panax ginseng. OBJECTIVE:The aim of this study was to evaluate the effect of ginsenoside Rb3 on myocardial ischemia-reperfusion injury in rats...

journal_title：Pharmaceutical biology

authors： Shi Y,Han B,Yu X,Qu S,Sui D

更新日期：2011-09-01 00:00:00

abstract：CONTEXT:Cotinus coggygria Scop. (Anacardiaceae) leaves that were used as wound healing in traditional Balkan and Anatolian folk medicine, could be potentially effective in treating diabetic wounds. OBJECTIVE:This study investigates biochemical and histological effects of ethanol extract of C. coggygria (CCE) on excisi...

journal_title：Pharmaceutical biology

authors： Aksoy H,Sen A,Sancar M,Sekerler T,Akakin D,Bitis L,Uras F,Kultur S,Izzettin FV

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Safranal (SAF) is verified to have potential effects in promoting nerve growth. OBJECTIVES:This study verifies the role of SAF in promoting dopaminergic neurons growth in vitro and in vivo. MATERIAL AND METHODS:Rat neural stem cells (NSC) were treated with 1, 20, or 100 ng/mL of SAF, and the expression levels...

journal_title：Pharmaceutical biology

authors： Zhao Y,Xi G

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Cardioprotective effects of various plants are generally attributed to their antioxidant activity. The whole fruit extract of pomegranate (WFEP), Punica granatum L. (Punicaceae), has a potent antioxidant activity. OBJECTIVE:To investigate cardioprotective effect of WFEP against doxorubicin (Dox)-induced cardio...

journal_title：Pharmaceutical biology

authors： Hassanpour Fard M,Ghule AE,Bodhankar SL,Dikshit M

更新日期：2011-04-01 00:00:00

abstract：CONTEXT:The extraction method and the crude wound healing effects of sacchachitin from Ganoderma tsugae Murr. (Ganodermataceae) has been cited. However, its purity is still largely limited. OBJECTIVE:An improvement of the fractionation protocol to purify the sacchachitin from Ganoderma lucidum L. (Ganodermataceae) (SG...

journal_title：Pharmaceutical biology

authors： Chuang CM,Wang HE,Chang CH,Peng CC,Ker YB,Lai JE,Chen KC,Peng RY

更新日期：2013-01-01 00:00:00

abstract：CONTEXT:Naringin is a bioflavonoid derivative and is predominantly found in Citrus paradisi Macf., Citrus sinensis (Linn.) Osbeck, Citrus unshiu Marc., Citrus reticulata Blanco cv. Nobilis, Citrus tachibana (Makino) Tanaka, Citrus junos Sieb. ex Tanaka (Rutaceae), and related citrus species. It has anti-inflammatory ef...

journal_title：Pharmaceutical biology

authors： Si-Si W,Liao L,Ling Z,Yun-Xia Y

更新日期：2011-08-01 00:00:00

abstract：CONTEXT:Phytochemical and pharmacological data on Ducrosia anethifolia (DC.) Boiss. (Apiaceae), an Iranian medicinal plant, are scarce; however, furocoumarins are characteristic compounds of D. anethifolia. OBJECTIVE:Our experiments identify the secondary metabolites of D. anethifolia and assess their antitumor and an...

journal_title：Pharmaceutical biology

authors： Mottaghipisheh J,Nové M,Spengler G,Kúsz N,Hohmann J,Csupor D

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:To date, there are no reports to validate the Indian traditional and folklore claims of Artemisia maderaspatana L. (syn. Grangea maderaspatana L.) (Asteraceae) for the treatment of Alzheimer's disease. OBJECTIVE:The present study characterizes the volatile components (non-polar compounds) of A. maderaspatana a...

journal_title：Pharmaceutical biology

authors： Jyotshna,Srivastava N,Singh B,Chanda D,Shanker K

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Pisonia aculeata leaves (Nyctagenaceae), a Folk medicinal plant used in the treatment of several inflammation, pain, and oxidative stress associated diseases. OBJECTIVE:To evaluate anti-inflammatory, analgesic, and antioxidant potential of crude methanol extract of P. aculeata leaves (MEPA). MATERIALS AND MET...

journal_title：Pharmaceutical biology

authors： Sen S,Chakraborty R,Rekha B,Revathi D,Ayyanna SC,Hemalatha G,Kumar Reddy GA,Hyndavi S,Ikhyatha Babu PJ,Prakash PR,Sridhar C

更新日期：2013-04-01 00:00:00

abstract：:Nine species belonging to the genus Lippia - Verbenaceae - are used in Argentine folk medicine. Four of them are known under the trivial name "poleo": L. turbinata Griseb., L. fissicalyx Troncoso, L. integrifolia (Griseb.) Hieron. and L. grisebachiana Mold. Mainly, their leaves are employed as digestive, stomaquique, ...

journal_title：Pharmaceutical biology

authors： Bassols GB,Gurni AA

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Granulocyte colony stimulating factor (G-CSF) has been commonly used to treat neutropenia caused by chemotherapy, radiotherapy, and organ transplants. Improved in vitro efficacy of G-CSF has already been observed by conjugating it to polyethylene glycol (PEG). OBJECTIVE:The in vivo bioassay using tetrazolium d...

journal_title：Pharmaceutical biology

authors： Tiwari K,Wavdhane M,Haque S,Govender T,Kruger HG,Mishra MK,Chandra R,Tiwari D

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:Oysters [Crassostrea plicatula Gmelin (Ostreidae)] are widely used for food in coastal areas. It is reported to have several qualities such as improving sexual and immune function. They has been approved by Chinese Ministry of Health as a functional food. OBJECTIVE:The effects of five types of oyster component...

journal_title：Pharmaceutical biology

authors： Hao G,Zhang C,Cao W,Hao J

更新日期：2014-06-01 00:00:00

abstract：CONTEXT:The Boraginaceae family comprises plants that have important therapeutic and cosmetic applications. Their pharmacological effect is related to the presence of naphthaquinones, flavonoids, terpenoids, phenols, or purine derivative - allantoin. OBJECTIVE:In the present study, comparison of some secondary metabol...

journal_title：Pharmaceutical biology

authors： Dresler S,Szymczak G,Wójcik M

更新日期：2017-12-01 00:00:00

abstract：:Heliopsis longipes S.F. Blake (Asteraceae: Heliantheae) (chilcuague) is used in Mexican traditional medicine against parasites and to alleviate tooth and muscle pains. Its biocide effect has already been experimentally demonstrated; however, its analgesic action and its action on the nervous system (NS) have not been ...

journal_title：Pharmaceutical biology

authors： Cilia-López VG,Juárez-Flores BI,Aguirre-Rivera JR,Reyes-Agüero JA

更新日期：2010-02-01 00:00:00

abstract：CONTEXT:Brassicaceae plants are associated with protection against cancers due to their glucosinolate contents. OBJECTIVES:We investigate fresh leaves, roots and ripe seeds of Lobularia libyca (Viv.) C.F.W. Meissn. (Brassicaceae) to identify their glucosinolate constituents, antimicrobial and cytotoxic activities Mate...

journal_title：Pharmaceutical biology

authors： Al-Gendy AA,Nematallah KA,Zaghloul SS,Ayoub NA

更新日期：2016-12-01 00:00:00

abstract：:Context Pelargonium sidoides DC (Geraniaceae) is an important medicinal plant indigenous to South Africa and Lesotho. Previous studies have shown that root extracts are rich in polyphenolic compounds with antibacterial, antiviral and immunomodulatory activities. Little is known regarding the anticancer properties of P...

journal_title：Pharmaceutical biology

authors： Pereira A,Bester M,Soundy P,Apostolides Z

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:Polygonum species have been used in the treatment of several types of inflammatory disorders and cancer. Nevertheless, there are no reports related to the anti-inflammatory and anti-proliferative activities of Polygonum bellardii All. (Polygonaceae). OBJECTIVE:This study investigated the chemical composition o...

journal_title：Pharmaceutical biology

authors： Abd El-Kader AM,El-Readi MZ,Ahmed AS,Nafady AM,Wink M,Ibraheim ZZ

更新日期：2013-08-01 00:00:00

abstract：CONTEXT:Cucurbitacins are a group of triterpenoids that have a cucurbitane skeleton with a wide range of biological activities. OBJECTIVES:This study evaluated the anticancer properties of one cucurbitacin isolated from Cayaponia racemosa Cong. (Cucurbitaceae), 2β,3β,16α,20(R),25-pentahydroxy-22-oxocucurbita-5-en (1),...

journal_title：Pharmaceutical biology

authors： Militão GC,Dantas IN,Ferreira PM,Alves AP,Chaves DC,Monte FJ,Pessoa C,Odorico de Moraes M,Costa-Lotufo LV

更新日期：2012-12-01 00:00:00