Safranal-promoted differentiation and survival of dopaminergic neurons in an animal model of Parkinson's disease.

abstract：CONTEXT:Polygonum species have been used in the treatment of several types of inflammatory disorders and cancer. Nevertheless, there are no reports related to the anti-inflammatory and anti-proliferative activities of Polygonum bellardii All. (Polygonaceae). OBJECTIVE:This study investigated the chemical composition o...

journal_title：Pharmaceutical biology

authors： Abd El-Kader AM,El-Readi MZ,Ahmed AS,Nafady AM,Wink M,Ibraheim ZZ

更新日期：2013-08-01 00:00:00

abstract：CONTENT:Rosa damascena Mill. (Rosaceae) is an important ornamental and medicinal plant and a source of fragrance. Its hydrosol is known in Iran as golab (rose water) and has applications in religious ceremonies, food, and pharmaceuticals. Hydrosol is traditionally and industrially produced by distillation. The increase...

journal_title：Pharmaceutical biology

authors： Moein M,Zarshenas MM,Delnavaz S

更新日期：2014-10-01 00:00:00

abstract：UNLABELLED:CONTEXT. Huperzia saururus (Lam.) Trevis. (Lycopodiaceae), an autochthonous plant species in Argentina, is used as a memory improver in traditional medicine. It was studied for this reason and the purified alkaloid extract did show significant activity on learning and memory. The species is mostly consumed i...

journal_title：Pharmaceutical biology

authors： Vallejo MG,Dimmer JA,Ortega MG,Cabrera JL,Agnese AM

更新日期：2013-10-01 00:00:00

abstract：CONTEXT:The genus Premna (Lamiaceae), distributed throughout tropical and subtropical Asia, Africa, Australia and the Pacific Islands, is used in folk medicine primarily to treat inflammation, immune-related diseases, stomach disorders, wound healing, and skin diseases. OBJECTIVES:This review exhaustively gathers avai...

journal_title：Pharmaceutical biology

authors： Dianita R,Jantan I

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Cotinus coggygria Scop. (Anacardiaceae) leaves that were used as wound healing in traditional Balkan and Anatolian folk medicine, could be potentially effective in treating diabetic wounds. OBJECTIVE:This study investigates biochemical and histological effects of ethanol extract of C. coggygria (CCE) on excisi...

journal_title：Pharmaceutical biology

authors： Aksoy H,Sen A,Sancar M,Sekerler T,Akakin D,Bitis L,Uras F,Kultur S,Izzettin FV

更新日期：2016-11-01 00:00:00

abstract：:Escin, a group of chemically related triterpenic glycosides, is widely used in commercial preparations for the treatment of venous insufficiency. Since the zygotic embryo cotyledons accumulate the highest amount of escin, it is currently extracted from the seeds of horse chestnut, Aesculus hippocastanum L. (Hippocasta...

journal_title：Pharmaceutical biology

authors： Calić-Dragosavac D,Zdravković-Korać S,Savikin-Fodulović K,Radojević L,Vinterhalter B

更新日期：2010-05-01 00:00:00

abstract：CONTEXT:Withania somnifera (Linn.) Dunal (Solanaceae) has long been used as an herb in Ayurvedic and indigenous medicine and has received intense attention in recent years for its chemopreventive properties. OBJECTIVE:The present study focuses on the effect of W. somnifera root powder on the behavioral and radiologica...

journal_title：Pharmaceutical biology

authors： Gupta A,Singh S

更新日期：2014-03-01 00:00:00

abstract：CONTEXT:Polygonum multiflorum is known as a medicinal plant. It has been used as a folk medicine which showed antioxidative property. OBJECTIVE:Protective effects of the water extracts (w/v:1/10) from fresh P. multiflorum (WEP) on carbon tetrachloride (CCl(4))-induced liver damage in rats were investigated. MATERIALS...

journal_title：Pharmaceutical biology

authors： Lee BH,Huang YY,Duh PD,Wu SC

更新日期：2012-03-01 00:00:00

abstract：CONTEXT:The content of withanolides in the roots of Withania somnifera (L.) Dunal (Solanaceae) is important for therapeutic application. Earlier studies have shown that the deficiency of macro- and micronutrients affects the growth of W. somnifera. Therefore, we examined the effect of these deficiencies on the withanol...

journal_title：Pharmaceutical biology

authors： Devkar ST,Suryapujary SM,Jagtap SD,Katyare SS,Hegde MV

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the aqueous extract from aerial parts of Artemisia copa Phil. (Asteraceae) administered orallyfor its psychopharmacological activities in several experimental models. METHODS:The extract was administered p.o. in Swiss albino mice and tested on pentobarbital-induced hypnosis, locomotor activity, e...

journal_title：Pharmaceutical biology

authors： Miño JH,Moscatelli V,Acevedo C,Ferraro G

更新日期：2010-12-01 00:00:00

abstract：CONTEXT:The incidence and mortality of thrombotic disorders are rapidly increasing throughout the world. Therefore, attempts have been made to develop new anticoagulant and antithrombotic drugs. Our previous studies showed that a novel protein, named Fu-P, had fibrinogenolytic activity and much higher fibrinolytic acti...

journal_title：Pharmaceutical biology

authors： Wu B,Xu J

更新日期：2012-07-01 00:00:00

abstract：:Abstract Context: Galbanic acid (GA) is a biologically active sesquiterpene coumarin from Ferula species (Apiaceae). This compound showed various biological properties including anticancer, cancer chemopreventive, anticoagulant, antiviral, and antileishmanial activities. Objectives: This article is a review on the syn...

journal_title：Pharmaceutical biology

authors： Kasaian J,Iranshahy M,Iranshahi M

更新日期：2013-12-13 00:00:00

abstract：CONTEXT:Lycopene is a phytonutrient under considerable investigation for its antioxidant benefits in treating diseases like cancer, cardiovascular diseases, osteoporosis and diabetes. OBJECTIVE:This study explores the effect of lycopene against oxidative damage during experimental hepatitis, induced by D-galactosamine...

journal_title：Pharmaceutical biology

authors： Sheik Abdulazeez S,Thiruvengadam D

更新日期：2013-12-01 00:00:00

abstract：CONTEXT:Baohuoside-I was reported to induce apoptosis in non-small-cell lung cancer and inhibit the growth of multiple myeloma cells. The antitumour potential of baohuoside-I has not been demonstrated in melanoma yet. OBJECTIVE:To investigate the potential antitumour activity of baohuoside-I against melanoma and eluci...

journal_title：Pharmaceutical biology

authors： Peng YG,Zhang L

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Viola tianshanica Maxim. (Violaceae) is a perennial herb distributed in Central Asia, especially in the Xinjiang Uygur Autonomous Region (XUAR) of China. Preliminary study showed that the ethanol extract of the herb exhibited the anti-complement activity against the classical pathway, but the active components ...

journal_title：Pharmaceutical biology

authors： Qin Y,Wen Q,Cao J,Yin C,Chen D,Cheng Z

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:Salvicine is a pharmacologically active derivative from Chinese medicinal plant Salvia prionitis Hance (Labiatae). It has been reported that salvicine inactivates β1 integrin and inhibits integrin-mediated cell adhesion to fibronectin. Given the emerging correlation between integrins and angiogenesis, we propos...

journal_title：Pharmaceutical biology

authors： Zhang Y,Wang L,Chen Y,Qing C

更新日期：2013-08-01 00:00:00

abstract：CONTEXT:Prunella vulgaris L. (Labiatae) is a perennial plant common in China and Europe and is rich in rosmarinic acid (RA), ursolic acid (UA), and oleanolic acid (OA). The dried spica of P. vulgaris has been used as traditional medicine in China for over a hundred years. To our best knowledge, no study has been conduc...

journal_title：Pharmaceutical biology

authors： Chen Y,Guo Q,Zhu Z,Zhang L

更新日期：2012-09-01 00:00:00

abstract：:Context Phillyrea latifolia L. (Oleaceae), commonly found in the Mediterranean region in Turkey, is used as medicinal teas for weight loss and hyperglycaemia in folk medicine. Objective The study investigated the possible effects of P. latifolia leaves aqueous extract's on weight loss and biochemical-histological chan...

journal_title：Pharmaceutical biology

authors： Yazici-Tutunis S,Gurel-Gurevin E,Ustunova S,Demirci-Tansel C,Mericli F

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:A previous study demonstrated that the chloroform extract of Salvia connivens Epling (Lamiaceae) has anti-inflammatory activity. OBJECTIVE:Identification of the active components in the dicholorometane extract (DESC), and, standardization of the extract based in ursolic acid. MATERIAL AND METHODS:DESC was pre...

journal_title：Pharmaceutical biology

authors： González-Chávez MM,Ramos-Velázquez CS,Serrano-Vega R,Pérez-González C,Sánchez-Mendoza E,Pérez-Gutiérrez S

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Hyperthermia causes detrimental effects on the testes leading to fertility problems. Mallotus roxbhurghianus Muell. Arg. (Euphorbiaceae) is used in traditional medicine and possesses antioxidant property. However, the mechanisms remain unknown in the context of alleviative action of M. roxburghianus against hea...

journal_title：Pharmaceutical biology

authors： Kumar Roy V,Marak TR,Gurusubramanian G

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:The application of bleomycin is limited due to its side effects including lung toxicity. Silymarin is a flavonoid complex isolated from milk thistle [Silybum marianum L. (Asteraceae)] which has been identified as an antioxidant and anti-inflammatory compound. OBJECTIVE:This study evaluates the effect of silyma...

journal_title：Pharmaceutical biology

authors： Razavi-Azarkhiavi K,Ali-Omrani M,Solgi R,Bagheri P,Haji-Noormohammadi M,Amani N,Sepand MR

更新日期：2014-10-01 00:00:00

abstract：:Context:Caragana pruinosa Kom. (Fabaceae), a commonly used folk medicine, has been found to possess antitumor effects. However, the antiproliferative effect of 2,4-dihydroxy-3'-methoxy-4'-ethoxychalcone (DMEC) derived from C. pruinosa against multiple myeloma (MM) has never been investigated. Objective: This study sys...

journal_title：Pharmaceutical biology

authors： Zhu F,Jiang D,Zhang M,Zhao B

更新日期：2019-12-01 00:00:00

abstract：CONTEXT:Different parts of Punica granatum Linn. (Punicaceae) are traditionally used as renal protective agents in the Indian system of medicine. However, there is paucity of information regarding its role in diabetic nephropathy. OBJECTIVE:The present study investigates the nephroprotective potential of flavonoid-ric...

journal_title：Pharmaceutical biology

authors： Ankita P,Deepti B,Nilam M

更新日期：2015-01-01 00:00:00

abstract：:Context Shengmai injection (SMI) is a patented Chinese medicine originated from the ancient Chinese herbal compound Shengmai san, which is used extensively for the treatment of cardiovascular and cerebrovascular disease in the clinic. Objective To determine the neuroprotective effect of SMI, we investigated the effect...

journal_title：Pharmaceutical biology

authors： Yang H,Li L,Zhou K,Wang Y,Guan T,Chai C,Kou J,Yu B,Yan Y

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Vicenin-1, a flavonol glycoside, has potent platelet aggregation inhibition, antioxidant, radioprotectants and anti-inflammatory activities. OBJECTIVE:To establish a rapid, simple, precise and sensitive high-performance liquid chromatography (HPLC) method for determination of vicenin-1 in rat plasma, and to in...

journal_title：Pharmaceutical biology

authors： Kandhare AD,Bodhankar SL,Mohan V,Thakurdesai PA

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Ginger has been used commonly in the traditional system of medicine for the treatment of respiratory disorders. OBJECTIVE:The present study investigates the immunosuppressive activity of ginger by using the mouse model of ovalbumin-induced allergic asthma. MATERIALS AND METHODS:Treatment with ethanol extract ...

journal_title：Pharmaceutical biology

authors： Khan AM,Shahzad M,Raza Asim MB,Imran M,Shabbir A

更新日期：2015-03-01 00:00:00

abstract：:Nine species belonging to the genus Lippia - Verbenaceae - are used in Argentine folk medicine. Four of them are known under the trivial name "poleo": L. turbinata Griseb., L. fissicalyx Troncoso, L. integrifolia (Griseb.) Hieron. and L. grisebachiana Mold. Mainly, their leaves are employed as digestive, stomaquique, ...

journal_title：Pharmaceutical biology

authors： Bassols GB,Gurni AA

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Silymarin (SM) is extracted from milk thistle Silybum marianum L. [Asteraceae (Compositae)] and known for antioxidative and anti-inflammatory effects. OBJECTIVE:The potential antidepressant-like effect of acute SM and possible involvement of nitric oxide (NO) were determined in male mice. MATERIAL AND METHODS...

journal_title：Pharmaceutical biology

authors： Khoshnoodi M,Fakhraei N,Dehpour AR

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:Bombacaceae is a small family of the order Malvales and contains about 28 genera and 200 species. Members of this family are not only showy ornamentals but they possess significant economical and commercial reputation as well. In addition, various plant parts of several species are widely used as foods and trad...

journal_title：Pharmaceutical biology

authors： Refaat J,Desoky SY,Ramadan MA,Kamel MS

更新日期：2013-01-01 00:00:00

abstract：CONTEXT:Hypertrophic scarring, a common proliferative disorder of dermal fibroblasts, results from an overproduction of collagen and excessive deposition of extracellular matrix. Although the treatment with surgical excisions or steroid hormones can modify the symptoms, numerous treatment-related complications have als...

journal_title：Pharmaceutical biology

authors： Wu JG,Wei YJ,Ran X,Zhang H,Nian H,Qin LP

更新日期：2011-07-01 00:00:00