Anti-angiogenic activity of salvicine.

abstract：CONTEXT:Indian mustard [Brassica juncea (L.) Czern. & Coss. (Brassicaceae)] is reported to possess diverse pharmacological properties. However, limited information is available concerning its hepatoprotective activity and mechanism of action. OBJECTIVE:To study the protective mechanism of mustard seed extract against ...

journal_title：Pharmaceutical biology

authors： Parikh H,Pandita N,Khanna A

更新日期：2015-07-01 00:00:00

abstract：CONTEXT:Ferulago angulata (Schlecht.) Boiss. (Apiaceae) (FASB) is used to treat liver diseases and has been used both as food and therapeutics by many cultures for thousands of years because of the natural antioxidant compounds. OBJECTIVE:This study determines antioxidant properties of FASB flowers, the levels of mine...

journal_title：Pharmaceutical biology

authors： Kiziltas H,Ekin S,Bayramoglu M,Akbas E,Oto G,Yildirim S,Ozgokce F

更新日期：2017-12-01 00:00:00

abstract：:Different extracts from the stem bark of Berberis asiatica L. , a plant traditionally used to hasten the process of wound healing, and the alkaloid fractions derived from the commonly used aqueous extract, were tested for their putative antimicrobial activity against a battery of microorganisms by disk diffusion and a...

journal_title：Pharmaceutical biology

authors： Bhandari DK,Nath G,Ray AB,Tewari PV

更新日期：2000-01-01 00:00:00

abstract：:Context Phillyrea latifolia L. (Oleaceae), commonly found in the Mediterranean region in Turkey, is used as medicinal teas for weight loss and hyperglycaemia in folk medicine. Objective The study investigated the possible effects of P. latifolia leaves aqueous extract's on weight loss and biochemical-histological chan...

journal_title：Pharmaceutical biology

authors： Yazici-Tutunis S,Gurel-Gurevin E,Ustunova S,Demirci-Tansel C,Mericli F

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Carissa edulis Vahl (Apocynaceae) is used in Nigerian folk medicine to manage a plethora of diseases including epilepsy, cancer, and inflammation; its efficacy is widely acclaimed among communities of northern Nigeria. OBJECTIVE:This study establishes anticonvulsant activities of aqueous fraction of ethanol ro...

journal_title：Pharmaceutical biology

authors： Ya'u J,Yaro AH,Malami S,Musa MA,Abubakar A,Yahaya SM,Chindo BA,Anuka JA,Hussaini IM

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a tropical tree that has many folk uses in various countries. The bark extract is used for the control of the fresh water snails that act as intermediary host of Schistosoma. OBJECTIVE:Study the molluscicidal activity and chemical constituents of seed oil an...

journal_title：Pharmaceutical biology

authors： Dawidar AE,Mortada MM,Raghib HM,Abdel-Mogib M

更新日期：2012-10-01 00:00:00

abstract：CONTEXT:Hypertrophic scarring, a common proliferative disorder of dermal fibroblasts, results from an overproduction of collagen and excessive deposition of extracellular matrix. Although the treatment with surgical excisions or steroid hormones can modify the symptoms, numerous treatment-related complications have als...

journal_title：Pharmaceutical biology

authors： Wu JG,Wei YJ,Ran X,Zhang H,Nian H,Qin LP

更新日期：2011-07-01 00:00:00

abstract：CONTEXT:Curcumol has recently attracted special attention due to its potential activities in many chronic disorders. Moreover, the traditional role of turmeric [Curcuma longa L. (Zingiberaceae)] in suppression of hyperglycemia is of great interest. OBJECTIVES:The present work explores the potential acute and subchroni...

journal_title：Pharmaceutical biology

authors： Raafat KM,Omar AG

更新日期：2016-08-01 00:00:00

abstract：:Context: Cisplatin-based chemotherapy was widely used in treating human malignancies. However, side effects and chemoresistance remains the major obstacle.Objective: To verify whether natural borneol (NB) can enhance cisplatin-induced glioma cell apoptosis and explore the mechanism.Materials and methods: Cytotoxicity ...

journal_title：Pharmaceutical biology

authors： Cao WQ,Zhai XQ,Ma JW,Fu XQ,Zhao BS,Zhang P,Fu XY

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the abnormal accumulation of β-amyloid (Aβ). Multiple Aβ-aggregated species have been identified, and neurotoxicity appears to be correlated with the amount of non-fibrillar oligomers. Potent inhibitors of Aβ oligomer formation or Aβ-indu...

journal_title：Pharmaceutical biology

authors： Song Y,Kim HD,Lee MK,Kim MK,Kang SN,Ko YG,Won CK,Kim GS,Lee SS,Bai HW,Chung BY,Cho JH

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Red ginseng (heat-processed Panax ginseng) is a well-known alternative medicine with pharmacological antidiabetic activity. It exerts pharmacological effects through the transformation of saponin into metabolites by the intestinal microbiota. Given that intestinal conditions and intestinal microflora vary among...

journal_title：Pharmaceutical biology

authors： Jang SH,Park J,Kim SH,Choi KM,Ko ES,Cha JD,Lee YR,Jang H,Jang YS

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Amaranthus spinosus Linn. (Amaranthaceae), commonly known as ''spiny pigweed'', is used in both Indian traditional system and folk medicine for treatment of infectious diseases for a long time in several traditional herbal medicinal preparations. A novel fatty acid [(14E, 18E, 22E, 26E)-methyl nonacosa-14, 18, ...

journal_title：Pharmaceutical biology

authors： Mondal A,Maity TK

更新日期：2016-10-01 00:00:00

abstract：CONTENT:Rosa damascena Mill. (Rosaceae) is an important ornamental and medicinal plant and a source of fragrance. Its hydrosol is known in Iran as golab (rose water) and has applications in religious ceremonies, food, and pharmaceuticals. Hydrosol is traditionally and industrially produced by distillation. The increase...

journal_title：Pharmaceutical biology

authors： Moein M,Zarshenas MM,Delnavaz S

更新日期：2014-10-01 00:00:00

abstract：:Context Diabetes is a global health challenge. Although large prospective clinical trials have shown that intensive control of blood glucose or blood pressure reduces the risk for development and progression of vascular complications in diabetes, a substantial number of diabetic patients still experience renal failure...

journal_title：Pharmaceutical biology

authors： Yamagishi S,Matsui T

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Cancer chemopreventive action of walnut [Juglans regia L. (Juglandaceae)] has been explored. OBJECTIVE:This study evaluated antiproliferative and antioxidant activities of walnut. MATERIALS AND METHODS:Various fractions of walnut extract have been screened for antiproliferative activity against human cancer c...

journal_title：Pharmaceutical biology

authors： Negi AS,Luqman S,Srivastava S,Krishna V,Gupta N,Darokar MP

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the aqueous extract from aerial parts of Artemisia copa Phil. (Asteraceae) administered orallyfor its psychopharmacological activities in several experimental models. METHODS:The extract was administered p.o. in Swiss albino mice and tested on pentobarbital-induced hypnosis, locomotor activity, e...

journal_title：Pharmaceutical biology

authors： Miño JH,Moscatelli V,Acevedo C,Ferraro G

更新日期：2010-12-01 00:00:00

abstract：CONTEXT:α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). OBJECTIVE:TPN was assessed for its antinociceptive activity in rodents. MATERIALS AND METHODS:The antinociceptive effect of TPN was examined using the acetic acid writhing reflex,...

journal_title：Pharmaceutical biology

authors： Quintans-Júnior LJ,Oliveira MG,Santana MF,Santana MT,Guimarães AG,Siqueira JS,De Sousa DP,Almeida RN

更新日期：2011-06-01 00:00:00

abstract：UNLABELLED:Context Murraya paniculata (L.) Jack (Rutaceae), Qianlixiang in Chinese, is distributed in China. As an important traditional Chinese medicine (TCM), it demonstrates many bioactivities, such as febrifuge, astringent, anti-dysenteric, and tonic. OBJECTIVE:The objective of this study is to evaluate the anti-i...

journal_title：Pharmaceutical biology

authors： Wu J,Liu K,Shi X

更新日期：2016-01-01 00:00:00

abstract：:Context: Puerarin and triptolide are sometimes used together for the treatment of disease in Chinese clinics; however, the drug-drug interaction between puerarin and triptolide is still unknown. Objective: This study investigates the effects of puerarin on the pharmacokinetics of triptolide in rats and clarifies its m...

journal_title：Pharmaceutical biology

authors： Wang Q,Wu Y,Xiang F,Feng Y,Li Z,Ding Y

更新日期：2019-12-01 00:00:00

abstract：CONTEXT:Diabetes mellitus is characterized by oxidative stress, which in turn induces endothelial dysfunction. As a potent antioxidant compound, lycopene might rescue diabetic endothelial dysfunction by reducing oxidative stress. OBJECTIVE:The present study investigated whether lycopene could lower oxidative stress an...

journal_title：Pharmaceutical biology

authors： Zhu J,Wang CG,Xu YG

更新日期：2011-11-01 00:00:00

abstract：CONTEXT:Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities. OBJECTIVE:The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicit...

journal_title：Pharmaceutical biology

authors： Al-Ashaal HA,El-Sheltawy ST

更新日期：2011-03-01 00:00:00

abstract：CONTEXT:Cardioprotective effects of various plants are generally attributed to their antioxidant activity. The whole fruit extract of pomegranate (WFEP), Punica granatum L. (Punicaceae), has a potent antioxidant activity. OBJECTIVE:To investigate cardioprotective effect of WFEP against doxorubicin (Dox)-induced cardio...

journal_title：Pharmaceutical biology

authors： Hassanpour Fard M,Ghule AE,Bodhankar SL,Dikshit M

更新日期：2011-04-01 00:00:00

abstract：:Chemical constituents as well as cytotoxic and insecticidal activity of the crude methanol extract from the leaves of Phyllanthus reticulatus Poir. (Euphorbiaceae) were investigated. (5R*,6R*)-4,6-Dimethoxycarbonyl-5-[2',3',4'-trihydroxy-6'-(methoxycarbonyl) phenyl]-5,6-dihydro-2H-pyran-2-one (1) along with 3,4,3'-tri...

journal_title：Pharmaceutical biology

authors： Pojchaijongdee N,Sotanaphun U,Limsirichaikul S,Poobrasert O

更新日期：2010-07-01 00:00:00

abstract：CONTEXT:Light microscopy is in most cases a quick method for the identification and discrimination of medicinally used plant drugs; moreover, this technique is very inexpensive. Reliable descriptions of the anatomy of plants and their adulterations are prerequisites for necessary purity controls. OBJECTIVE:The anatomy...

journal_title：Pharmaceutical biology

authors： Fritz E,Saukel J

更新日期：2011-08-01 00:00:00

abstract：CONTEXT:Psoralen and anastrozole are always used together for breast cancer patients in Chinese clinics. OBJECTIVE:This study investigates the effects of psoralen on the pharmacokinetics of anastrozole in rats and its potential mechanism. MATERIALS AND METHODS:The pharmacokinetics of orally administered anastrozole (...

journal_title：Pharmaceutical biology

authors： Zhang Y,Wu J,Zhou Y,Yin Y,Chen H

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (CVDs). However, there are no studies on the effects of Crataegus monogyna Jacq. (Rosaceae) and C. davisii Browicz on thrombosis, which is an important mechanism in CVDs. OBJECTIVE:The purpose of this study was to inve...

journal_title：Pharmaceutical biology

authors： Arslan R,Bektas N,Bor Z,Sener E

更新日期：2015-02-01 00:00:00

abstract：CONTEXT:Linum usitatissimum L. (Linaceae), commonly known as flaxseed, is a good source of dietary fiber and lignans. Earlier we reported cardioprotective, antihyperlipidemic, and in vitro antioxidant activity of flax lignan concentrate (FLC) obtained from flaxseed. OBJECTIVES:To isolate secoisolariciresinol diglucosi...

journal_title：Pharmaceutical biology

authors： Zanwar AA,Hegde MV,Rojatkar SR,Sonawane KB,Rajamohanan PR,Bodhankar SL

更新日期：2014-09-01 00:00:00

abstract：CONTEXT:Recent studies have shown compound Danshen dripping pills (CDDP) could improve microcirculation in ischemic/reperfusion injury and other microvascular disorders. The mechanism for CDDP's role in microcirculation is not clear. OBJECTIVE:To explore the protective effects of CDDP on microvascular dysfunction. MA...

journal_title：Pharmaceutical biology

authors： Zhang Y,Zhao J,Ding R,Niu W,He Z,Liang C

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:The roots of Phytolacca americana L. (Phytolaccaceae) may be toxic. Despite heated controversy over the toxic compounds of P. americana, especially esculentosides, relevant studies remain scarce. OBJECTIVE:The objective of this study is to screen the toxic fractions and compounds of P. americana, to determine ...

journal_title：Pharmaceutical biology

authors： Yu H,Gong L,Wang X,Wu H,Zhao T,Wang K,Cui X,Chen L

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Ferula cupularis (Boiss.) Spalik et S. R. Downie (Apiaceae) is a common plant in Iran that grows in the foothills of Dena Mountain. In traditional folk medicine, this plant has different applications, but there are no studies proving their uses. OBJECTIVE:This study is the first attempt to investigate the chem...

journal_title：Pharmaceutical biology

authors： Alipour Z,Taheri P,Samadi N

更新日期：2015-04-01 00:00:00