Effects of psoralen on the pharmacokinetics of anastrozole in rats.

abstract：CONTEXT:Ferulago angulata (Schlecht.) Boiss. (Apiaceae) (FASB) is used to treat liver diseases and has been used both as food and therapeutics by many cultures for thousands of years because of the natural antioxidant compounds. OBJECTIVE:This study determines antioxidant properties of FASB flowers, the levels of mine...

journal_title：Pharmaceutical biology

authors： Kiziltas H,Ekin S,Bayramoglu M,Akbas E,Oto G,Yildirim S,Ozgokce F

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (CVDs). However, there are no studies on the effects of Crataegus monogyna Jacq. (Rosaceae) and C. davisii Browicz on thrombosis, which is an important mechanism in CVDs. OBJECTIVE:The purpose of this study was to inve...

journal_title：Pharmaceutical biology

authors： Arslan R,Bektas N,Bor Z,Sener E

更新日期：2015-02-01 00:00:00

abstract：CONTEXT:Indian mustard [Brassica juncea (L.) Czern. & Coss. (Brassicaceae)] is reported to possess diverse pharmacological properties. However, limited information is available concerning its hepatoprotective activity and mechanism of action. OBJECTIVE:To study the protective mechanism of mustard seed extract against ...

journal_title：Pharmaceutical biology

authors： Parikh H,Pandita N,Khanna A

更新日期：2015-07-01 00:00:00

abstract：CONTEXT:Glycyrrhiza glabra L. (Febaceae) has been widely used in traditional medicine and scientifically explored for its anticonvulsant and memory improving potential. OBJECTIVE:The objective of this study is to investigate the effect of flavonoid rich fraction of G. glabra root extract against phenytoin-induced cogn...

journal_title：Pharmaceutical biology

authors： Singh P,Singh D,Goel RK

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:The fruits of Aronia melanocarpa Elliot (Rosaceae), (black chokeberry), and Sambucus nigra L. (Caprifoliaceae), elderberries are rich in anthocyanins. Many studies have reported that anthocyanins are beneficial in diabetes due to their capacity to stimulate insulin secretion and reduce oxidative stress. OBJECT...

journal_title：Pharmaceutical biology

authors： Badescu M,Badulescu O,Badescu L,Ciocoiu M

更新日期：2015-04-01 00:00:00

abstract：CONTEXT:Neuropsychiatric disorders, like anxiety and depression, are global problems for clinical researchers in neurology. Recently, some authors have shown neuroprotective and anti-inflammatory effects of Scrophularia striata Boiss (Scrophulariaceae) extract in rodents. OBJECTIVE:The purpose of the current study was...

journal_title：Pharmaceutical biology

authors： Kosari-Nasab M,Babri S,Fatehi-Gharehlar L,Doosti MH,Pakzad S

更新日期：2013-05-01 00:00:00

abstract：CONTEXT:Tournefortia sarmentosa Lam. (Boraginaceae), a Chinese herbal medicine, is commonly used as a detoxicant or anti-inflammatory agent. OBJECTIVE:As acetaminophen (APAP) is a well-known hepatotoxin, we investigated the effect of the aqueous extract of the T. sarmentosa on APAP-induced hepatotoxicity in vivo and i...

journal_title：Pharmaceutical biology

authors： Teng CY,Lai YL,Huang HI,Hsu WH,Yang CC,Kuo WH

更新日期：2012-03-01 00:00:00

abstract：CONTEXT:Calotropis procera (Ait.) R. Br. (Asclepiadaceae), Ficus elastica Roxb. (Moraceae) and Zingiber officinale Roscoe (Zingiberaceae) have been traditionally used to treat many diseases. OBJECTIVE:The antischistosomal activity of these plant extracts was evaluated against Schistosoma mansoni. MATERIALS AND METHOD...

journal_title：Pharmaceutical biology

authors： Seif el-Din SH,El-Lakkany NM,Mohamed MA,Hamed MM,Sterner O,Botros SS

更新日期：2014-02-01 00:00:00

abstract：CONTEXT:Safranal (SAF) is verified to have potential effects in promoting nerve growth. OBJECTIVES:This study verifies the role of SAF in promoting dopaminergic neurons growth in vitro and in vivo. MATERIAL AND METHODS:Rat neural stem cells (NSC) were treated with 1, 20, or 100 ng/mL of SAF, and the expression levels...

journal_title：Pharmaceutical biology

authors： Zhao Y,Xi G

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Cancer, being a cause of death for major fraction of population worldwide, is one of the most studied diseases and is being investigated for the development of new technologies and more accurate therapies. Still the currently available therapies for cancer have many lacunae which affect the patient's health sev...

journal_title：Pharmaceutical biology

authors： Rai M,Jogee PS,Agarkar G,dos Santos CA

更新日期：2016-01-01 00:00:00

abstract：:Context The underground edible tuber of Dioscorea alata L. (Dioscoreaceae) is a functional food with high nutritive value and therapeutic potential. The tuber is known to possess anti-inflammatory properties in traditional medicine. Objective The present study explores the anti-inflammatory activity and standardisatio...

journal_title：Pharmaceutical biology

authors： Dey P,Roy Chowdhuri S,Sarkar MP,Chaudhuri TK

更新日期：2016-08-01 00:00:00

abstract：CONTEXT:Griflola frondosa (Fr) S.F. Gray (Meripilaceae) (GF) is a medical mushroom, and its regulation of the immune system is of interest for the treatment of mood disorders. α-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors are the central mediator for the treatment of depression. OBJECTIVE:This...

journal_title：Pharmaceutical biology

authors： Bao H,Ran P,Sun L,Hu W,Li H,Xiao C,Zhu K,Du J

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Hydroxysafflor yellow A (HSYA) has been shown to have neuroprotective effects in cerebral infarction. However, its underlying roles in apoptosis and inflammation in Parkinson's disease (PD) are unknown. OBJECTIVE:The present study investigates the effects and underlying mechanisms of HSYA on dopaminergic (DA) ...

journal_title：Pharmaceutical biology

authors： Yang X,Li Y,Chen L,Xu M,Wu J,Zhang P,Nel D,Sun B

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Depression is one of the most common psychiatric diseases. Acorus tatarinowii Schott (Araceae) has shown many bioactivities in treatment of senile dementia and epilepsy. However, there is no report on antidepressant-like effects of the essential oil (EO) and its major components on animals under standardized ex...

journal_title：Pharmaceutical biology

authors： Han P,Han T,Peng W,Wang XR

更新日期：2013-05-01 00:00:00

abstract：CONTEXT:Eryngium maritimum L. and the endemic Eryngium kotschyi Boiss. of the Apiaceae family are used for antiinflammatory, antivenom, antinociceptive and diuretic purposes in folk medicine in Turkey. OBJECTIVE:This study investigated the cytotoxic effects of the plant extracts belonging to Eryngium L. genus on vario...

journal_title：Pharmaceutical biology

authors： Yurdakök B,Baydan E

更新日期：2013-12-01 00:00:00

abstract：CONTEXT:Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a tropical tree that has many folk uses in various countries. The bark extract is used for the control of the fresh water snails that act as intermediary host of Schistosoma. OBJECTIVE:Study the molluscicidal activity and chemical constituents of seed oil an...

journal_title：Pharmaceutical biology

authors： Dawidar AE,Mortada MM,Raghib HM,Abdel-Mogib M

更新日期：2012-10-01 00:00:00

abstract：CONTEXT:Silymarin (SM) is extracted from milk thistle Silybum marianum L. [Asteraceae (Compositae)] and known for antioxidative and anti-inflammatory effects. OBJECTIVE:The potential antidepressant-like effect of acute SM and possible involvement of nitric oxide (NO) were determined in male mice. MATERIAL AND METHODS...

journal_title：Pharmaceutical biology

authors： Khoshnoodi M,Fakhraei N,Dehpour AR

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:The application of bleomycin is limited due to its side effects including lung toxicity. Silymarin is a flavonoid complex isolated from milk thistle [Silybum marianum L. (Asteraceae)] which has been identified as an antioxidant and anti-inflammatory compound. OBJECTIVE:This study evaluates the effect of silyma...

journal_title：Pharmaceutical biology

authors： Razavi-Azarkhiavi K,Ali-Omrani M,Solgi R,Bagheri P,Haji-Noormohammadi M,Amani N,Sepand MR

更新日期：2014-10-01 00:00:00

abstract：CONTEXT:Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the abnormal accumulation of β-amyloid (Aβ). Multiple Aβ-aggregated species have been identified, and neurotoxicity appears to be correlated with the amount of non-fibrillar oligomers. Potent inhibitors of Aβ oligomer formation or Aβ-indu...

journal_title：Pharmaceutical biology

authors： Song Y,Kim HD,Lee MK,Kim MK,Kang SN,Ko YG,Won CK,Kim GS,Lee SS,Bai HW,Chung BY,Cho JH

更新日期：2015-01-01 00:00:00

abstract：:Context Phyllanthus emblica L. (Euphorbiaceae) (amla), Manilkara zapota L.P. Royen (Sapotaceae) (sapota) and silymarin are reported to contain antioxidant effects. However, information on other biological activities relating to the anti-aging properties is limited. Objective To compare in vitro antioxidants, anti-coll...

journal_title：Pharmaceutical biology

authors： Pientaweeratch S,Panapisal V,Tansirikongkol A

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:Polygonum species have been used in the treatment of several types of inflammatory disorders and cancer. Nevertheless, there are no reports related to the anti-inflammatory and anti-proliferative activities of Polygonum bellardii All. (Polygonaceae). OBJECTIVE:This study investigated the chemical composition o...

journal_title：Pharmaceutical biology

authors： Abd El-Kader AM,El-Readi MZ,Ahmed AS,Nafady AM,Wink M,Ibraheim ZZ

更新日期：2013-08-01 00:00:00

abstract：CONTEXT:Light microscopy is in most cases a quick method for the identification and discrimination of medicinally used plant drugs; moreover, this technique is very inexpensive. Reliable descriptions of the anatomy of plants and their adulterations are prerequisites for necessary purity controls. OBJECTIVE:The anatomy...

journal_title：Pharmaceutical biology

authors： Fritz E,Saukel J

更新日期：2011-08-01 00:00:00

abstract：CONTEXT:Solenostemon monostachyus P. Beauv (Lamiaceae) is an important herb used traditionally in the treatment of malaria, fever, and other diseases. OBJECTIVES:Antiplasmodial and antipyretic activities of S. monostachyus aerial extract were evaluated to ascertain the folkloric claim of its antimalarial and antipyret...

journal_title：Pharmaceutical biology

authors： Okokon J,Davis KA,Azare BA

更新日期：2016-01-01 00:00:00

abstract：CONTEXT: Despite the myriad uses of Annona senegalensis Pers. (Annonaceae) leaves in folklore medicine of Nigeria, the basis is yet to be substantiated by scientific investigations. OBJECTIVES: To investigate the antioxidant (in vitro and in vivo) and drug detoxification potential of aqueous extract of A. senegalensis...

journal_title：Pharmaceutical biology

authors： Ajboye TO,Yakubu MT,Salau AK,Oladiji AT,Akanji MA,Okogun JI

更新日期：2010-12-01 00:00:00

abstract：:The novel compound 1'''-hydroxy-2''',3'''-epoxylupinifolin ( 1 ), together with three known prenylated flavanones were identified from the stem of Derris reticulata during our reinvestigation of the plant. The structures were determined by spectroscopic methods including detailed study of NMR spectral data (DEPT, 2D-C...

journal_title：Pharmaceutical biology

authors： Prawat H,Mahidol C,Ruchirawat S

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Rutin, a flavonoid commonly present in onions, apples and tea, has been suggested to have a variety of pharmacological activities, including immunomodulator, anti-inflammatory and antioxidant activities. OBJECTIVES:The present study was to examine the protective effects of rutin on gastric mucosal damage induc...

journal_title：Pharmaceutical biology

authors： Liu Y,Gou L,Fu X,Li S,Lan N,Yin X

更新日期：2013-07-01 00:00:00

abstract：:Context Acetaminophen (APAP), also known as paracetamol and N-acetyl p-aminophenol, is one of the most frequently used drugs for analgesic and antipyretic purposes on a worldwide basis. It is safe and effective at recommended doses but has the potential for causing hepatotoxicity and acute liver failure (ALF) with ove...

journal_title：Pharmaceutical biology

authors： Eugenio-Pérez D,Montes de Oca-Solano HA,Pedraza-Chaverri J

更新日期：2016-10-01 00:00:00

abstract：:Clitoria ternatea , commonly known as Shankpushpi, is widely used in the traditional Indian system of medicine as a brain tonic and is believed to promote memory and intelligence. We examined the effectiveness of alcoholic extracts of aerial and root parts of C. ternatea at 300 and 500 mg/kg doses orally in rats in at...

journal_title：Pharmaceutical biology

authors： Taranalli AD,Cheeramkuzhy TC

更新日期：2000-01-01 00:00:00

abstract：:In the present study, the anxiolytic and sedative-hypnotic activities of polygalasaponins extracted from Polygala tenuifolia Willdenow (Polygalaceae) were determined in mice using hole-board, elevated plus maze, open field, and sodium pentobarbital-induced hypnosis tests. Moreover, the acute toxicity of polygalasaponi...

journal_title：Pharmaceutical biology

authors： Yao Y,Jia M,Wu JG,Zhang H,Sun LN,Chen WS,Rahman K

更新日期：2010-07-01 00:00:00

abstract：CONTEXT:Scrophularia genus (Scrophulariaceae) includes about 350 species commonly known as figwort. Many species of this genus grow wild in nature and have not been cultivated yet. However, some species are in danger of extinction. OBJECTIVE:This paper reviews the chemical compounds, biological activities and the ethn...

journal_title：Pharmaceutical biology

authors： Pasdaran A,Hamedi A

更新日期：2017-12-01 00:00:00