Evaluation of anti-inflammatory activity and standardisation of hydro-methanol extract of underground tuber of Dioscorea alata.

abstract：CONTEXT:Polygonum multiflorum is known as a medicinal plant. It has been used as a folk medicine which showed antioxidative property. OBJECTIVE:Protective effects of the water extracts (w/v:1/10) from fresh P. multiflorum (WEP) on carbon tetrachloride (CCl(4))-induced liver damage in rats were investigated. MATERIALS...

journal_title：Pharmaceutical biology

authors： Lee BH,Huang YY,Duh PD,Wu SC

更新日期：2012-03-01 00:00:00

abstract：CONTEXT:α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). OBJECTIVE:TPN was assessed for its antinociceptive activity in rodents. MATERIALS AND METHODS:The antinociceptive effect of TPN was examined using the acetic acid writhing reflex,...

journal_title：Pharmaceutical biology

authors： Quintans-Júnior LJ,Oliveira MG,Santana MF,Santana MT,Guimarães AG,Siqueira JS,De Sousa DP,Almeida RN

更新日期：2011-06-01 00:00:00

abstract：CONTEXT:Buchenavia tetraphylla (Aubl.) RA Howard (Combretaceae: Combretoideae) is an ethnomedicinal plant with reported antifungal action. OBJECTIVE:This study evaluates the antimicrobial activity of B. tetraphylla leaf extracts against clinical isolates of Candida albicans. The morphological alterations, combinatory ...

journal_title：Pharmaceutical biology

authors： Cavalcanti Filho JR,Silva TF,Nobre WQ,Oliveira de Souza LI,Silva E Silva Figueiredo CS,Figueiredo RC,de Gusmão NB,Silva MV,Nascimento da Silva LC,Correia MT

更新日期：2017-12-01 00:00:00

abstract：UNLABELLED:CONTEXT. Huperzia saururus (Lam.) Trevis. (Lycopodiaceae), an autochthonous plant species in Argentina, is used as a memory improver in traditional medicine. It was studied for this reason and the purified alkaloid extract did show significant activity on learning and memory. The species is mostly consumed i...

journal_title：Pharmaceutical biology

authors： Vallejo MG,Dimmer JA,Ortega MG,Cabrera JL,Agnese AM

更新日期：2013-10-01 00:00:00

abstract：CONTEXT:Linum usitatissimum L. (Linaceae), commonly known as flaxseed, is a good source of dietary fiber and lignans. Earlier we reported cardioprotective, antihyperlipidemic, and in vitro antioxidant activity of flax lignan concentrate (FLC) obtained from flaxseed. OBJECTIVES:To isolate secoisolariciresinol diglucosi...

journal_title：Pharmaceutical biology

authors： Zanwar AA,Hegde MV,Rojatkar SR,Sonawane KB,Rajamohanan PR,Bodhankar SL

更新日期：2014-09-01 00:00:00

abstract：:Context Syzygium densiflorum Wall. ex Wight & Arn (Myrtaceae) has been traditionally used by local tribes of the Nilgiris, Tamil Nadu, India, for the treatment of diabetes, however, no definitive experimental studies are available. Objective This study investigates the antidiabetic, antihyperlipidaemic and antioxidant...

journal_title：Pharmaceutical biology

authors： Krishnasamy G,Muthusamy K,Chellappan DR,Subbiah N

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:Silymarin, a flavonolignan from Silybum marianum (L.) Gaertn. (Asteraceae), has been reported to have antioxidant and anti-inflammatory properties. Therefore, it may be worthwhile to study the effect of silymarin on wound healing. OBJECTIVE:To evaluate the effect of silymarin on human fibroblast cells in an in...

journal_title：Pharmaceutical biology

authors： Sharifi R,Pasalar P,Kamalinejad M,Dehpour AR,Tavangar SM,Paknejad M,Mehrabani Natanzi M,Nourbakhsh M,Ahmadi Ashtiani HR,Akbari M,Rastegar H

更新日期：2013-03-01 00:00:00

abstract：CONTEXT:Curcumol has recently attracted special attention due to its potential activities in many chronic disorders. Moreover, the traditional role of turmeric [Curcuma longa L. (Zingiberaceae)] in suppression of hyperglycemia is of great interest. OBJECTIVES:The present work explores the potential acute and subchroni...

journal_title：Pharmaceutical biology

authors： Raafat KM,Omar AG

更新日期：2016-08-01 00:00:00

abstract：CONTEXT:Cancer, being a cause of death for major fraction of population worldwide, is one of the most studied diseases and is being investigated for the development of new technologies and more accurate therapies. Still the currently available therapies for cancer have many lacunae which affect the patient's health sev...

journal_title：Pharmaceutical biology

authors： Rai M,Jogee PS,Agarkar G,dos Santos CA

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Clerodendrum viscosum Vent. (Verbenaceae) is a shrub, widely used amongst the natives of India against various diseases. OBJECTIVE:Crude extract of the plant was tested in vitro on a tapeworm Raillietina tetragona Molin (Davaineidae) to evaluate its potential anthelmintic efficacy and ultrastructural changes i...

journal_title：Pharmaceutical biology

authors： Nandi S,Ukil B,Roy S,Kundu S,Lyndem LM

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Peripheral axon injury and degeneration are often mediated by oxidative stress and inflammation. The hydroalcoholic extract of the red propolis (HERP) has attracted great attention because of its antioxidant and anti-inflammatory activities. OBJECTIVE:The objective of this work is to study the effect of HERP o...

journal_title：Pharmaceutical biology

authors： Barbosa RA,Nunes TL,Nunes TL,da Paixão AO,Belo Neto R,Moura S,Albuquerque Junior RL,Cândido EA,Padilha FF,Quintans-Júnior LJ,Gomes MZ,Cardoso JC

更新日期：2016-01-01 00:00:00

abstract：:Context: Emodin is a compound in Rheum undulatum Linne (Polygonaceae) that has been reported to exert anti-inflammatory, antibacterial, and antiallergic effects.Objective: Oxidative stress is a causative agent of liver inflammation that may lead to fibrosis and hepato-carcinoma. In this study, we investigated the anti...

journal_title：Pharmaceutical biology

authors： Lee EH,Baek SY,Park JY,Kim YW

更新日期：2020-12-01 00:00:00

abstract：:Context Ginseng is a widely used herbal medicine in China but its mechanism of action remains unclear. Objective The objectives of this work were to study the protective effect of ginsenoside Rg1 on subacute murine renal damage induced by d-galactose and its mechanism. Materials and methods C57BL/6J mice were injected...

journal_title：Pharmaceutical biology

authors： Fan Y,Xia J,Jia D,Zhang M,Zhang Y,Huang G,Wang Y

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:The Boraginaceae family comprises plants that have important therapeutic and cosmetic applications. Their pharmacological effect is related to the presence of naphthaquinones, flavonoids, terpenoids, phenols, or purine derivative - allantoin. OBJECTIVE:In the present study, comparison of some secondary metabol...

journal_title：Pharmaceutical biology

authors： Dresler S,Szymczak G,Wójcik M

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Stress-induced changes in the dopaminergic system and subsequent enhancement of oxidative load and behavior are associated with a wide range of central and peripheral nervous disorders. Dopamine acts as a key neurotransmitter in the brain plays an important role in the regulation of motor and limbic functions. ...

journal_title：Pharmaceutical biology

authors： Alghasham A,Rasheed N

更新日期：2014-03-01 00:00:00

abstract：CONTEXT:The fruit of the Prunus mume Sieb. et Zucc (Rosaceae) is used as a health food or medicinal material in traditional herb medicine for a long time in Eastern Asian countries. OBJECTIVE:Our present study investigated the hypouricemic effect of the methanol extract from P. mume fruit (MPMF) in mice with potassium...

journal_title：Pharmaceutical biology

authors： Yi LT,Li J,Su DX,Dong JF,Li CF

更新日期：2012-11-01 00:00:00

abstract：CONTEXT:Recent studies have shown compound Danshen dripping pills (CDDP) could improve microcirculation in ischemic/reperfusion injury and other microvascular disorders. The mechanism for CDDP's role in microcirculation is not clear. OBJECTIVE:To explore the protective effects of CDDP on microvascular dysfunction. MA...

journal_title：Pharmaceutical biology

authors： Zhang Y,Zhao J,Ding R,Niu W,He Z,Liang C

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Aquatic organisms (especially fish) require potent defense mechanisms to protect themselves against pathogen invasion and disease formation. The use of immunostimulants in fish culture can prevent the diseases through augmentation of both specific and non-specific immunity. OBJECTIVE:A study was conducted to i...

journal_title：Pharmaceutical biology

authors： Pratheepa V,Ramesh S,Sukumaran N

更新日期：2010-11-01 00:00:00

abstract：CONTEXT:Urtica dioica L. (Urticaceae), stinging nettle, has been employed as a folklore remedy for a wide spectrum of ailments, including urinary disorders, prostatic hyperplasia, and liver diseases. It has been also used traditionally for cancer treatment. OBJECT:To evaluate the potential chemopreventive properties o...

journal_title：Pharmaceutical biology

authors： Di Sotto A,Mazzanti G,Savickiene N,Staršelskytė R,Baksenskaite V,Di Giacomo S,Vitalone A

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:Sepsis continues to be a significant problem for critical care patients. OBJECTIVE:To evaluate the protective effects of IgM-enriched immunoglobulin and erythropoietin on pulmonary and small intestine tissues in a rat model of intra-abdominal sepsis induced via the cecal ligation and puncture (CLP) method. MA...

journal_title：Pharmaceutical biology

authors： Ates I,Dogan N,Aksoy M,Halıcı Z,Gündogdu C,Keles MS

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Granulocyte colony stimulating factor (G-CSF) has been commonly used to treat neutropenia caused by chemotherapy, radiotherapy, and organ transplants. Improved in vitro efficacy of G-CSF has already been observed by conjugating it to polyethylene glycol (PEG). OBJECTIVE:The in vivo bioassay using tetrazolium d...

journal_title：Pharmaceutical biology

authors： Tiwari K,Wavdhane M,Haque S,Govender T,Kruger HG,Mishra MK,Chandra R,Tiwari D

更新日期：2015-06-01 00:00:00

abstract：:Context Acetaminophen (APAP), also known as paracetamol and N-acetyl p-aminophenol, is one of the most frequently used drugs for analgesic and antipyretic purposes on a worldwide basis. It is safe and effective at recommended doses but has the potential for causing hepatotoxicity and acute liver failure (ALF) with ove...

journal_title：Pharmaceutical biology

authors： Eugenio-Pérez D,Montes de Oca-Solano HA,Pedraza-Chaverri J

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Alpinia oxyphylla Miquel (Zingiberaceae) is a traditional Chinese herbal medicine widely used for the treatment of intestinal disorders, urosis and diuresis. However, information about antioxidant and cytotoxic properties of its fruits remains to be elucidated. OBJECTIVE:The ethanol crude extract (CE) and its ...

journal_title：Pharmaceutical biology

authors： Wang CZ,Yuan HH,Bao XL,Lan MB

更新日期：2013-11-01 00:00:00

abstract：CONTEXT:Termitomyces clypeatus (Lyophyllaceae) is a filamentous edible mushroom, having ethnomedicinal uses. However, information about the antioxidant, anticancer and antitumour properties of this mushroom remains to be elucidated. OBJECTIVE:The study examines the in vitro antioxidant, anticancer and in vivo antitumo...

journal_title：Pharmaceutical biology

authors： Mondal A,Banerjee D,Majumder R,Maity TK,Khowala S

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Herbal therapies are used worldwide to treat health conditions. In Mexico, generations have used them to treat gingivitis, periodontitis, mouth infections, and discoloured teeth. However, few studies have collected scientific evidence on their effects. OBJECTIVE:This study aimed at searching and compiling scie...

journal_title：Pharmaceutical biology

authors： Cruz Martínez C,Diaz Gómez M,Oh MS

更新日期：2017-12-01 00:00:00

abstract：:Context: Cisplatin-based chemotherapy was widely used in treating human malignancies. However, side effects and chemoresistance remains the major obstacle.Objective: To verify whether natural borneol (NB) can enhance cisplatin-induced glioma cell apoptosis and explore the mechanism.Materials and methods: Cytotoxicity ...

journal_title：Pharmaceutical biology

authors： Cao WQ,Zhai XQ,Ma JW,Fu XQ,Zhao BS,Zhang P,Fu XY

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Zhi-Zi-Hou-Pu decoction (ZZHPD) is a traditional prescription which has been used to treat "Yu-syndrome" (depression and melancholia) in Chinese herbal medication. OBJECTIVE:To evaluate antidepressant activities of ZZHPD, its fractions and possible mechanism(s) of action. MATERIALS AND METHODS:ZZHPD (1241, 24...

journal_title：Pharmaceutical biology

authors： Yao AM,Ma FF,Zhang LL,Feng F

更新日期：2013-02-01 00:00:00

abstract：CONTEXT:One traditional medicines, Hypericum perforatum L. (Hypericaceae), possesses several beneficial effects against depression, ulcers, dyspepsia, abdominal pains, burns, bacterial infections, migraine headaches, and sciatica. OBJECTIVE:The present study investigates the antimicrobial activity of the ethanol extra...

journal_title：Pharmaceutical biology

authors： Süntar I,Oyardı O,Akkol EK,Ozçelik B

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:The resistance of bacteria to antibiotics is raising serious concern globally. Asian medicinal plants could improve the current treatment strategies for bacterial infections. The antibacterial properties of medicinal plants used by the Khyang tribe in Bangladesh have not been investigated. OBJECTIVE:The presen...

journal_title：Pharmaceutical biology

authors： Hossan MS,Jindal H,Maisha S,Samudi Raju C,Devi Sekaran S,Nissapatorn V,Kaharudin F,Su Yi L,Khoo TJ,Rahmatullah M,Wiart C

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Anemarsaponin BII is one of the most active saponins isolated from Anemarrhena asphodeloides Bunge (Asparagaceae), a commonly used Chinese traditional paediatric medicine. OBJECTIVE:This study investigates the effects of anemarsaponin BII on the activity of CYP450s to provide more guidance for the clinical use...

journal_title：Pharmaceutical biology

authors： Wang M,Jiang W,Zhou J,Xue X,Yin C

更新日期：2020-12-01 00:00:00