Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family.

abstract：CONTEXT:One traditional medicines, Hypericum perforatum L. (Hypericaceae), possesses several beneficial effects against depression, ulcers, dyspepsia, abdominal pains, burns, bacterial infections, migraine headaches, and sciatica. OBJECTIVE:The present study investigates the antimicrobial activity of the ethanol extra...

journal_title：Pharmaceutical biology

authors： Süntar I,Oyardı O,Akkol EK,Ozçelik B

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Carissa edulis Vahl (Apocynaceae) is used in Nigerian folk medicine to manage a plethora of diseases including epilepsy, cancer, and inflammation; its efficacy is widely acclaimed among communities of northern Nigeria. OBJECTIVE:This study establishes anticonvulsant activities of aqueous fraction of ethanol ro...

journal_title：Pharmaceutical biology

authors： Ya'u J,Yaro AH,Malami S,Musa MA,Abubakar A,Yahaya SM,Chindo BA,Anuka JA,Hussaini IM

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Stress-induced changes in the dopaminergic system and subsequent enhancement of oxidative load and behavior are associated with a wide range of central and peripheral nervous disorders. Dopamine acts as a key neurotransmitter in the brain plays an important role in the regulation of motor and limbic functions. ...

journal_title：Pharmaceutical biology

authors： Alghasham A,Rasheed N

更新日期：2014-03-01 00:00:00

abstract：CONTEXT:Cancer, being a cause of death for major fraction of population worldwide, is one of the most studied diseases and is being investigated for the development of new technologies and more accurate therapies. Still the currently available therapies for cancer have many lacunae which affect the patient's health sev...

journal_title：Pharmaceutical biology

authors： Rai M,Jogee PS,Agarkar G,dos Santos CA

更新日期：2016-01-01 00:00:00

abstract：:The effect of Celastrus paniculatus Willd. (Celastraceae) seed aqueous extract on learning and memory was studied using elevated plus maze and passive avoidance test (sodium nitrite induced amnesia rodent model). The aqueous seed extract was administered orally in two different doses to rats (350 and 1050 mg/kg) and t...

journal_title：Pharmaceutical biology

authors： Bhanumathy M,Harish MS,Shivaprasad HN,Sushma G

更新日期：2010-03-01 00:00:00

abstract：CONTEXT:Stachys guyoniana Noë ex. Batt. and Mentha aquatica L. are two Algerian Lamiaceae used in folk medicine. OBJECTIVE:To investigate their antioxidant, anticholinesterase and antibacterial activities. MATERIAL AND METHODS:n-Butanol (BESG), ethyl acetate (EESG) and chloroform (CESG) extracts of S. guyoniana and m...

journal_title：Pharmaceutical biology

authors： Ferhat M,Erol E,Beladjila KA,Çetintaş Y,Duru ME,Öztürk M,Kabouche A,Kabouche Z

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Polygonum multiflorum is known as a medicinal plant. It has been used as a folk medicine which showed antioxidative property. OBJECTIVE:Protective effects of the water extracts (w/v:1/10) from fresh P. multiflorum (WEP) on carbon tetrachloride (CCl(4))-induced liver damage in rats were investigated. MATERIALS...

journal_title：Pharmaceutical biology

authors： Lee BH,Huang YY,Duh PD,Wu SC

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the aqueous extract from aerial parts of Artemisia copa Phil. (Asteraceae) administered orallyfor its psychopharmacological activities in several experimental models. METHODS:The extract was administered p.o. in Swiss albino mice and tested on pentobarbital-induced hypnosis, locomotor activity, e...

journal_title：Pharmaceutical biology

authors： Miño JH,Moscatelli V,Acevedo C,Ferraro G

更新日期：2010-12-01 00:00:00

abstract：CONTEXT:The medicinal plants used in the traditional medicine of Rivers State of Nigeria were surveyed. OBJECTIVE:The survey aims to identify and document the plants used amongst the indigenes of Rivers State. MATERIALS AND METHODS:Semi-structured interviews were conducted during a field trip to gather information fr...

journal_title：Pharmaceutical biology

authors： Ajibesin KK,Bala DN,Umoh UF

更新日期：2012-09-01 00:00:00

abstract：CONTEXT:Indian mustard [Brassica juncea (L.) Czern. & Coss. (Brassicaceae)] is reported to possess diverse pharmacological properties. However, limited information is available concerning its hepatoprotective activity and mechanism of action. OBJECTIVE:To study the protective mechanism of mustard seed extract against ...

journal_title：Pharmaceutical biology

authors： Parikh H,Pandita N,Khanna A

更新日期：2015-07-01 00:00:00

abstract：:Context The underground edible tuber of Dioscorea alata L. (Dioscoreaceae) is a functional food with high nutritive value and therapeutic potential. The tuber is known to possess anti-inflammatory properties in traditional medicine. Objective The present study explores the anti-inflammatory activity and standardisatio...

journal_title：Pharmaceutical biology

authors： Dey P,Roy Chowdhuri S,Sarkar MP,Chaudhuri TK

更新日期：2016-08-01 00:00:00

abstract：:In the present study, the anxiolytic and sedative-hypnotic activities of polygalasaponins extracted from Polygala tenuifolia Willdenow (Polygalaceae) were determined in mice using hole-board, elevated plus maze, open field, and sodium pentobarbital-induced hypnosis tests. Moreover, the acute toxicity of polygalasaponi...

journal_title：Pharmaceutical biology

authors： Yao Y,Jia M,Wu JG,Zhang H,Sun LN,Chen WS,Rahman K

更新日期：2010-07-01 00:00:00

abstract：CONTEXT:Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a tropical tree that has many folk uses in various countries. The bark extract is used for the control of the fresh water snails that act as intermediary host of Schistosoma. OBJECTIVE:Study the molluscicidal activity and chemical constituents of seed oil an...

journal_title：Pharmaceutical biology

authors： Dawidar AE,Mortada MM,Raghib HM,Abdel-Mogib M

更新日期：2012-10-01 00:00:00

abstract：CONTEXT:Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities. OBJECTIVE:The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicit...

journal_title：Pharmaceutical biology

authors： Al-Ashaal HA,El-Sheltawy ST

更新日期：2011-03-01 00:00:00

abstract：CONTEXT:The poor prognostic outcome of breast cancer is largely due to its resistance to cancer therapies. Development of therapeutic agents that can inhibit growth and induce apoptosis in breast cancer cells can help solve the problem. Emodin is an active anthraquinone that has been reported to have diverse biological...

journal_title：Pharmaceutical biology

authors： Li WY,Chan RY,Yu PH,Chan SW

更新日期：2013-09-01 00:00:00

abstract：CONTEXT:Light microscopy is in most cases a quick method for the identification and discrimination of medicinally used plant drugs; moreover, this technique is very inexpensive. Reliable descriptions of the anatomy of plants and their adulterations are prerequisites for necessary purity controls. OBJECTIVE:The anatomy...

journal_title：Pharmaceutical biology

authors： Fritz E,Saukel J

更新日期：2011-08-01 00:00:00

abstract：CONTEXT:Polyphenols are naturally occurring compounds found in fruits, vegetables, cereals, and beverages. Polyphenols occupy a unique place in biological science for their pharmacological properties. Gossypol is a polyphenolic compound that has attracted attention because of its biological effects. OBJECTIVE:Gossypol...

journal_title：Pharmaceutical biology

authors： Keshmiri-Neghab H,Goliaei B

更新日期：2014-01-01 00:00:00

abstract：CONTEXT:Viola tianshanica Maxim. (Violaceae) is a perennial herb distributed in Central Asia, especially in the Xinjiang Uygur Autonomous Region (XUAR) of China. Preliminary study showed that the ethanol extract of the herb exhibited the anti-complement activity against the classical pathway, but the active components ...

journal_title：Pharmaceutical biology

authors： Qin Y,Wen Q,Cao J,Yin C,Chen D,Cheng Z

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:Urtica dioica L. (Urticaceae), stinging nettle, has been employed as a folklore remedy for a wide spectrum of ailments, including urinary disorders, prostatic hyperplasia, and liver diseases. It has been also used traditionally for cancer treatment. OBJECT:To evaluate the potential chemopreventive properties o...

journal_title：Pharmaceutical biology

authors： Di Sotto A,Mazzanti G,Savickiene N,Staršelskytė R,Baksenskaite V,Di Giacomo S,Vitalone A

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant. Its roots are used as the famous traditional Chinese medicine Huang-Qin, which is recorded in Chinese Pharmacopoeia, European Pharmacopoeia, and British Pharmacopoeia. OBJECTIVE:This review comprehensively summarizes research progress in ...

journal_title：Pharmaceutical biology

authors： Wang ZL,Wang S,Kuang Y,Hu ZM,Qiao X,Ye M

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Raspberry ketone (RK) is a natural phenolic compound of red raspberry. The dietary intake of RK has been reported to exert anti-obese actions and alter the lipid metabolism in vivo and human studies. OBJECTIVE:To elucidate a possible mechanism for anti-obese actions of RK, the effects of RK on the adipogenic a...

journal_title：Pharmaceutical biology

authors： Park KS

更新日期：2015-06-01 00:00:00

abstract：CONTEXT:Naringin is a bioflavonoid derivative and is predominantly found in Citrus paradisi Macf., Citrus sinensis (Linn.) Osbeck, Citrus unshiu Marc., Citrus reticulata Blanco cv. Nobilis, Citrus tachibana (Makino) Tanaka, Citrus junos Sieb. ex Tanaka (Rutaceae), and related citrus species. It has anti-inflammatory ef...

journal_title：Pharmaceutical biology

authors： Si-Si W,Liao L,Ling Z,Yun-Xia Y

更新日期：2011-08-01 00:00:00

abstract：CONTEXT:Ginger has been used commonly in the traditional system of medicine for the treatment of respiratory disorders. OBJECTIVE:The present study investigates the immunosuppressive activity of ginger by using the mouse model of ovalbumin-induced allergic asthma. MATERIALS AND METHODS:Treatment with ethanol extract ...

journal_title：Pharmaceutical biology

authors： Khan AM,Shahzad M,Raza Asim MB,Imran M,Shabbir A

更新日期：2015-03-01 00:00:00

abstract：:The effects of isosaline extracts of Tetrapleura tetrapetra and Olax subscorpioides were investigated in albino rats. The treatment of rats with these extracts resulted in an increase in the activities of serum alanine aminotransferase, liver aspartate aminotransferase, alanine aminotransferase, acid phosphatase and a...

journal_title：Pharmaceutical biology

authors： Olagunju JA,Oyedapo OO,Onasanya BA,Osoba OO,Adebanjo OO,Eweje O,Shodeinde AB

更新日期：2000-01-01 00:00:00

abstract：:Different extracts from the stem bark of Berberis asiatica L. , a plant traditionally used to hasten the process of wound healing, and the alkaloid fractions derived from the commonly used aqueous extract, were tested for their putative antimicrobial activity against a battery of microorganisms by disk diffusion and a...

journal_title：Pharmaceutical biology

authors： Bhandari DK,Nath G,Ray AB,Tewari PV

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Red ginseng (heat-processed Panax ginseng) is a well-known alternative medicine with pharmacological antidiabetic activity. It exerts pharmacological effects through the transformation of saponin into metabolites by the intestinal microbiota. Given that intestinal conditions and intestinal microflora vary among...

journal_title：Pharmaceutical biology

authors： Jang SH,Park J,Kim SH,Choi KM,Ko ES,Cha JD,Lee YR,Jang H,Jang YS

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Different parts of Punica granatum Linn. (Punicaceae) are traditionally used as renal protective agents in the Indian system of medicine. However, there is paucity of information regarding its role in diabetic nephropathy. OBJECTIVE:The present study investigates the nephroprotective potential of flavonoid-ric...

journal_title：Pharmaceutical biology

authors： Ankita P,Deepti B,Nilam M

更新日期：2015-01-01 00:00:00

abstract：:Several drugs of herbal origin are known to possess anxiolytic and antidepressant effects. In a recent study, we showed that extracts from Euphorbia hirta L. (Euphorbiaceae) (Eh) demonstrated anxiolytic effects in rats subjected to chronic immobilization stress (CIS) but not in rats that underwent forced swim stress (...

journal_title：Pharmaceutical biology

authors： Anuradha H,Srikumar BN,Deepti N,Shankaranarayana Rao BS,Lakshmana M

更新日期：2010-05-01 00:00:00

abstract：CONTEXT:Phytochemical and pharmacological data on Ducrosia anethifolia (DC.) Boiss. (Apiaceae), an Iranian medicinal plant, are scarce; however, furocoumarins are characteristic compounds of D. anethifolia. OBJECTIVE:Our experiments identify the secondary metabolites of D. anethifolia and assess their antitumor and an...

journal_title：Pharmaceutical biology

authors： Mottaghipisheh J,Nové M,Spengler G,Kúsz N,Hohmann J,Csupor D

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines. OBJECTIVE:To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of 1 ...

journal_title：Pharmaceutical biology

authors： Sun J,Jiang T,Xu W,Feng Z,Quan X,Leng P,Sun W,Zhao J,Jing F,Li J

更新日期：2019-12-01 00:00:00