Effects of isosaline extracts of tetrapleura tetrapetra and olax subscorpioides on certain biochemical parameters of albino rats.

Abstract:

:The effects of isosaline extracts of Tetrapleura tetrapetra and Olax subscorpioides were investigated in albino rats. The treatment of rats with these extracts resulted in an increase in the activities of serum alanine aminotransferase, liver aspartate aminotransferase, alanine aminotransferase, acid phosphatase and alkaline phosphatase. The extract of Tetrapleura tetrapetra caused a significant increase in blood glucose and liver glycogen levels while the extract of Olax subscorpioides caused a slight reduction but not statistically significant in the levels of blood glucose and liver glycogen. Both extracts exhibited a significant reduction of protein in the livers of treated rats.

journal_name

Pharm Biol

journal_title

Pharmaceutical biology

authors

Olagunju JA,Oyedapo OO,Onasanya BA,Osoba OO,Adebanjo OO,Eweje O,Shodeinde AB

doi

10.1076/1388-0209(200007)3831-SFT187

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

187-91

issue

3

eissn

1388-0209

issn

1744-5116

journal_volume

38

pub_type

杂志文章
  • Effect of medium composition and light on root and rhinacanthin formation in Rhinacanthus nasutus cultures.

    abstract::Rhinacanthus nasutus (L.) Kurz (Acanthaceae) has long been used in Thai traditional medicine for treatment of tinea versicolor, ringworm, pruritic rash, and abscess. The active constituents are known as a group of naphthoquinone esters, rhinacanthins. This work focused on establishment of R. nasutus root cultures and ...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880200903578747

    authors: Panichayupakaranant P,Meerungrueang W

    更新日期:2010-11-01 00:00:00

  • Safranal-promoted differentiation and survival of dopaminergic neurons in an animal model of Parkinson's disease.

    abstract:CONTEXT:Safranal (SAF) is verified to have potential effects in promoting nerve growth. OBJECTIVES:This study verifies the role of SAF in promoting dopaminergic neurons growth in vitro and in vivo. MATERIAL AND METHODS:Rat neural stem cells (NSC) were treated with 1, 20, or 100 ng/mL of SAF, and the expression levels...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2018.1501705

    authors: Zhao Y,Xi G

    更新日期:2018-12-01 00:00:00

  • Chrysanthemum boreale flower floral water inhibits platelet-derived growth factor-stimulated migration and proliferation in vascular smooth muscle cells.

    abstract:CONTEXT:Chrysanthemum boreale Makino (Compositae) (CBM) is a traditional medicine that has been used for the prevention or treatment of various disorders; it has various properties including antioxidation, anti-inflammation, and antitumor. OBJECTIVE:The present study was designed to explore the in vitro effect of CBM ...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.941882

    authors: Kim DY,Won KJ,Yoon MS,Yu HJ,Park JH,Kim B,Lee HM

    更新日期:2015-05-01 00:00:00

  • Screening and identifying the myocardial-injury protective ingredients from Sheng-Mai-San.

    abstract:CONTEXT:Sheng-Mai-San (SMS) has been used for the treatment of cardiovascular disease for many years in China. OBJECTIVES:This study investigated the protective effects and active ingredients of SMS on myocardial injury (MI) in mice. MATERIALS AND METHODS:SMS and n-butanol extraction of SMS (SMS-Bu) were prepared and...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.784920

    authors: Wang YQ,Zhang JQ,Liu CH,Zhu DN,Yu BY

    更新日期:2013-10-01 00:00:00

  • The protective effects of IgM-enriched immunoglobulin and erythropoietin on the lung and small intestine tissues of rats with induced sepsis: biochemical and histopathological evaluation.

    abstract:CONTEXT:Sepsis continues to be a significant problem for critical care patients. OBJECTIVE:To evaluate the protective effects of IgM-enriched immunoglobulin and erythropoietin on pulmonary and small intestine tissues in a rat model of intra-abdominal sepsis induced via the cecal ligation and puncture (CLP) method. MA...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.910535

    authors: Ates I,Dogan N,Aksoy M,Halıcı Z,Gündogdu C,Keles MS

    更新日期:2015-01-01 00:00:00

  • Anticancer effect of 2,7-dihydroxy-3-methylanthraquinone on human gastric cancer SGC-7901 cells in vitro and in vivo.

    abstract:CONTEXT:2,7-Dihydroxy-3-methylanthraquinone (DDMN) is reported to have a remarkable anticancer activity against gastric cancer SGC-7901 cells. OBJECTIVE:The objective of this study is to study the anticancer effect and mechanism of DDMN on SGC-7901 cells. MATERIALS AND METHODS:The MTT assay was used to determine the ...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2015.1033563

    authors: Zhu H,Zheng Z,Zhang J,Liu X,Liu Y,Yang W,Liu Y,Zhang T,Zhao Y,Liu Y,Su X,Gu X

    更新日期:2016-01-01 00:00:00

  • Anemarsaponin BII inhibits the activity of CYP3A4, 2D6, and 2E1 with human liver microsomes.

    abstract:CONTEXT:Anemarsaponin BII is one of the most active saponins isolated from Anemarrhena asphodeloides Bunge (Asparagaceae), a commonly used Chinese traditional paediatric medicine. OBJECTIVE:This study investigates the effects of anemarsaponin BII on the activity of CYP450s to provide more guidance for the clinical use...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2020.1835996

    authors: Wang M,Jiang W,Zhou J,Xue X,Yin C

    更新日期:2020-12-01 00:00:00

  • Effects of Alismatis rhizome on rat cytochrome P450 enzymes.

    abstract:CONTEXT:Alismatis rhizome (RA) (Water Plantain Family, also called "Zexie" in Chinese), one of the commonly used components of traditional Chinese medicines, is derived from the dried rhizomes of Alisma orientalis (Sam.) Juzep. (Alismataceae). OBJECTIVE:This study explores the RA influences on rat cytochrome P450 (CYP...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.864685

    authors: Huang Y,Zheng SL,Xu ZS,Hou Y

    更新日期:2014-06-01 00:00:00

  • Molluscicidal activity of Balanites aegyptiaca against Monacha cartusiana.

    abstract:CONTEXT:Balanites aegyptiaca (L.) Delile (Zygophyllaceae) is a tropical tree that has many folk uses in various countries. The bark extract is used for the control of the fresh water snails that act as intermediary host of Schistosoma. OBJECTIVE:Study the molluscicidal activity and chemical constituents of seed oil an...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2012.674950

    authors: Dawidar AE,Mortada MM,Raghib HM,Abdel-Mogib M

    更新日期:2012-10-01 00:00:00

  • Formation of harmful compounds in biotransformation of lilial by microorganisms isolated from human skin.

    abstract:CONTEXT:The biotransformation of lilial results in an acid that is used in the dairy industry, in perfumery, as an intermediate in the manufacture of pharmaceuticals and cosmetics, and as a food additive for enhancing taste. OBJECTIVE:This study investigates the biotransformation of lilial by Staphylococcus aureus and...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2015.1005755

    authors: Esmaeili A,Afshari S,Esmaeili D

    更新日期:2015-01-01 00:00:00

  • Molluscicidal activity of Solanum elaeagnifolium seeds against Galba truncatula intermediate host of Fasciola hepatica: Identification of β-solamarine.

    abstract:CONTEXT:The persistence of fascioliasis in many developing countries urges the search for simple, cheap, and effective substances. In this view, plants provide interesting molluscicidal activities thanks to the secondary metabolites they produce. The genus Solanum is known for its potent effect on vector snails. OBJEC...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2015.1073332

    authors: Njeh F,Feki H,Koubaa I,Hamed N,Damak M,Ayadi A,Hammami H,Mezghani-Jarraya R

    更新日期:2016-01-01 00:00:00

  • Screening study of blood-supplementing active components in water decoction of Angelica sinensis processed with yellow rice wine based on response surface methodology.

    abstract:CONTEXT:Angelica sinensis (Oliv.) Diels (Apiaceae) (syn. Angelica polymorpha Maxim var. sinensis Oliver) processed with yellow rice wine (WAS) has a blood-supplementing effect. OBJECTIVE:To establish an optimal technology for preparing water decoction of WAS (WASD), and screen blood-supplementing fractions. MATERIALS...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2020.1844760

    authors: Ji P,Li C,Wei Y,Wu F,Liu S,Hua Y,Yao W,Zhang X,Yuan Z,Wen Y

    更新日期:2020-12-01 00:00:00

  • Antimicrobial bioassay-guided fractionation of a methanol extract of Eupatorium triplinerve.

    abstract:CONTEXT:Eupatorium triplinerve Vahl (Asteraceae), popularly known as Japana, is widely used in folk medicine, due its analgesic, anticoagulant, antianorexic, antiparasitic, anthelmintic, sedative, antifungal, and antibacterial properties. OBJECTIVE:The present study evaluated the chemical composition and antimicrobial...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.948634

    authors: Matos Lopes TR,de Oliveira FR,Malheiros FF,de Andrade MA,Monteiro MC,Baetas Gonçalves AC

    更新日期:2015-06-01 00:00:00

  • Involvement of GABAergic system in regulation of the anxiolytic- and antidepressant-like effects of Scrophularia striata extract in rats.

    abstract:CONTEXT:Neuropsychiatric disorders, like anxiety and depression, are global problems for clinical researchers in neurology. Recently, some authors have shown neuroprotective and anti-inflammatory effects of Scrophularia striata Boiss (Scrophulariaceae) extract in rodents. OBJECTIVE:The purpose of the current study was...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2012.749924

    authors: Kosari-Nasab M,Babri S,Fatehi-Gharehlar L,Doosti MH,Pakzad S

    更新日期:2013-05-01 00:00:00

  • Anticoccidial effect of Fructus Meliae toosendan extract against Eimeria tenella.

    abstract:CONTEXT:Fructus Meliae toosendan extracts (FMTE) have a good therapeutic effect on coccidiosis, but there is no relevant research on its prophylactic effect on coccidiosis. OBJECTIVE:This study comprehensively evaluates the anticoccidial effect of FMTE. MATERIALS AND METHODS:In vitro, the unsporulated oocysts were tr...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2020.1784234

    authors: Yong T,Chen M,Li Y,Song X,Huang Y,Chen Y,Jia R,Zou Y,Li L,Yin L,He C,Lv C,Liang X,Ye G,Yin Z

    更新日期:2020-12-01 00:00:00

  • Inhibition of invasion and metastasis of human liver cancer HCCLM3 cells by portulacerebroside A.

    abstract:CONTEXT:Portulacerebroside A (PCA) is a novel cerebroside compound isolated from Portulaca oleracea L. (Portulacaceae), an edible and medicinal plant distributed in the temperate and tropical zones worldwide. OBJECTIVE:This study investigates the effects of PCA in human liver cancer HCCLM3 cells on metastasis and inva...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.941505

    authors: Ji Q,Zheng GY,Xia W,Chen JY,Meng XY,Zhang H,Rahman K,Xin HL

    更新日期:2015-05-01 00:00:00

  • Effect of macronutrient deficiency on withanolides content in the roots of Withania somnifera and its correlationship with molybdenum content.

    abstract:CONTEXT:The content of withanolides in the roots of Withania somnifera (L.) Dunal (Solanaceae) is important for therapeutic application. Earlier studies have shown that the deficiency of macro- and micronutrients affects the growth of W. somnifera. Therefore, we examined the effect of these deficiencies on the withanol...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.931439

    authors: Devkar ST,Suryapujary SM,Jagtap SD,Katyare SS,Hegde MV

    更新日期:2015-04-01 00:00:00

  • Shengmai injection attenuates the cerebral ischemia/reperfusion induced autophagy via modulation of the AMPK, mTOR and JNK pathways.

    abstract::Context Shengmai injection (SMI) is a patented Chinese medicine originated from the ancient Chinese herbal compound Shengmai san, which is used extensively for the treatment of cardiovascular and cerebrovascular disease in the clinic. Objective To determine the neuroprotective effect of SMI, we investigated the effect...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2016.1155625

    authors: Yang H,Li L,Zhou K,Wang Y,Guan T,Chai C,Kou J,Yu B,Yan Y

    更新日期:2016-10-01 00:00:00

  • Evaluation of the antithrombotic effects of Crataegus monogyna and Crataegus davisii in the carrageenan-induced tail thrombosis model.

    abstract:CONTEXT:Crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (CVDs). However, there are no studies on the effects of Crataegus monogyna Jacq. (Rosaceae) and C. davisii Browicz on thrombosis, which is an important mechanism in CVDs. OBJECTIVE:The purpose of this study was to inve...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.914957

    authors: Arslan R,Bektas N,Bor Z,Sener E

    更新日期:2015-02-01 00:00:00

  • Influence of Emblica officinalis aqueous extract on growth and antioxidant defense system of human hepatoma cell line (HepG2).

    abstract:CONTEXT:Amla [Emblica officinalis Gaertn. (Euphorbiaceae)], a major constituent of several herbal formulations, is a well-known hepatoprotectant. Despite its extensive use, mechanistic understanding of its antioxidant action is rather limited. OBJECTIVE:In the current study, we investigated the effects of E. officinal...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2011.618501

    authors: Shivananjappa MM,Joshi MK

    更新日期:2012-04-01 00:00:00

  • Analgesic and anti-inflammatory effects of the methanol root extracts of some selected Nigerian medicinal plants.

    abstract:CONTEXT:The roots of Alafia barteri Oliver (Apocynaceae), Combretum mucronatum Schumach (Combretaceae) and Capparis thonningii Schum (Capparaceae) are used in Traditional African Medicine to alleviate painful and inflammatory conditions. OBJECTIVE:This study investigated the analgesic and anti-inflammatory effects of ...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.880487

    authors: Ishola IO,Agbaje EO,Adeyemi OO,Shukla R

    更新日期:2014-09-01 00:00:00

  • Reversal effects of Rabdosia rubescens extract on multidrug resistance of MCF-7/Adr cells in vitro.

    abstract:CONTEXT:Rabdosia rubescens (Hemsl.) Hara (Lamiaceae) is widely used in traditional Chinese medicines for the treatment of antitumor, antimicrobial, anti-inflammatory and antioxidation. It is also used as a supplement in the treatment of many cancers, such as esophagus, mammary gland, liver and prostate cancers. OBJECT...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.784342

    authors: Li F,Fan J,Wu Z,Liu RY,Guo L,Dong Z,Wang Z

    更新日期:2013-09-01 00:00:00

  • Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma.

    abstract:CONTEXT:The bacterium Pseudomonas syringae pv. syringae (Pss) is a pathogen of many plant species and causes, for example, brown spot disease in bean plants (Phaseolus vulgaris). Pss excretes the syringolins, natural product molecules that act as a virulence factors and inhibit the proteasome of the host plants. OBJEC...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2011.626784

    authors: Opoku-Ansah J,Ibarra-Rivera TR,Pirrung MC,Bachmann AS

    更新日期:2012-01-01 00:00:00

  • Chemical composition and antibacterial activity of the essential oils from flower, leaf and stem of Ferula cupularis growing wild in Iran.

    abstract:CONTEXT:Ferula cupularis (Boiss.) Spalik et S. R. Downie (Apiaceae) is a common plant in Iran that grows in the foothills of Dena Mountain. In traditional folk medicine, this plant has different applications, but there are no studies proving their uses. OBJECTIVE:This study is the first attempt to investigate the chem...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.924149

    authors: Alipour Z,Taheri P,Samadi N

    更新日期:2015-04-01 00:00:00

  • A sensitive WST-8-based bioassay for PEGylated granulocyte colony stimulating factor using the NFS-60 cell line.

    abstract:CONTEXT:Granulocyte colony stimulating factor (G-CSF) has been commonly used to treat neutropenia caused by chemotherapy, radiotherapy, and organ transplants. Improved in vitro efficacy of G-CSF has already been observed by conjugating it to polyethylene glycol (PEG). OBJECTIVE:The in vivo bioassay using tetrazolium d...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2014.943248

    authors: Tiwari K,Wavdhane M,Haque S,Govender T,Kruger HG,Mishra MK,Chandra R,Tiwari D

    更新日期:2015-06-01 00:00:00

  • Antioxidant, anti-collagenase and anti-elastase activities of Phyllanthus emblica, Manilkara zapota and silymarin: an in vitro comparative study for anti-aging applications.

    abstract::Context Phyllanthus emblica L. (Euphorbiaceae) (amla), Manilkara zapota L.P. Royen (Sapotaceae) (sapota) and silymarin are reported to contain antioxidant effects. However, information on other biological activities relating to the anti-aging properties is limited. Objective To compare in vitro antioxidants, anti-coll...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2015.1133658

    authors: Pientaweeratch S,Panapisal V,Tansirikongkol A

    更新日期:2016-09-01 00:00:00

  • Ethanol extract of Cotinus coggygria leaves accelerates wound healing process in diabetic rats.

    abstract:CONTEXT:Cotinus coggygria Scop. (Anacardiaceae) leaves that were used as wound healing in traditional Balkan and Anatolian folk medicine, could be potentially effective in treating diabetic wounds. OBJECTIVE:This study investigates biochemical and histological effects of ethanol extract of C. coggygria (CCE) on excisi...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2016.1181660

    authors: Aksoy H,Sen A,Sancar M,Sekerler T,Akakin D,Bitis L,Uras F,Kultur S,Izzettin FV

    更新日期:2016-11-01 00:00:00

  • Sacchachitin, a novel chitin-polysaccharide conjugate macromolecule present in Ganoderma lucidum: purification, composition, and properties.

    abstract:CONTEXT:The extraction method and the crude wound healing effects of sacchachitin from Ganoderma tsugae Murr. (Ganodermataceae) has been cited. However, its purity is still largely limited. OBJECTIVE:An improvement of the fractionation protocol to purify the sacchachitin from Ganoderma lucidum L. (Ganodermataceae) (SG...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2012.711840

    authors: Chuang CM,Wang HE,Chang CH,Peng CC,Ker YB,Lai JE,Chen KC,Peng RY

    更新日期:2013-01-01 00:00:00

  • Isolation, characterization and antihyperlipidemic activity of secoisolariciresinol diglucoside in poloxamer-407-induced experimental hyperlipidemia.

    abstract:CONTEXT:Linum usitatissimum L. (Linaceae), commonly known as flaxseed, is a good source of dietary fiber and lignans. Earlier we reported cardioprotective, antihyperlipidemic, and in vitro antioxidant activity of flax lignan concentrate (FLC) obtained from flaxseed. OBJECTIVES:To isolate secoisolariciresinol diglucosi...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.3109/13880209.2013.877492

    authors: Zanwar AA,Hegde MV,Rojatkar SR,Sonawane KB,Rajamohanan PR,Bodhankar SL

    更新日期:2014-09-01 00:00:00

  • Antibacterial effects of 18 medicinal plants used by the Khyang tribe in Bangladesh.

    abstract:CONTEXT:The resistance of bacteria to antibiotics is raising serious concern globally. Asian medicinal plants could improve the current treatment strategies for bacterial infections. The antibacterial properties of medicinal plants used by the Khyang tribe in Bangladesh have not been investigated. OBJECTIVE:The presen...

    journal_title:Pharmaceutical biology

    pub_type: 杂志文章

    doi:10.1080/13880209.2018.1446030

    authors: Hossan MS,Jindal H,Maisha S,Samudi Raju C,Devi Sekaran S,Nissapatorn V,Kaharudin F,Su Yi L,Khoo TJ,Rahmatullah M,Wiart C

    更新日期:2018-12-01 00:00:00