Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia.

abstract：CONTEXT:Several studies have demonstrated that essential oils and their major components have antioxidant activity. p-Cymene is a monoterpene and a major constituent of essential oils of various species of plants. OBJECTIVE:This paper evaluated the antioxidant potential of p-cymene in the hippocampus of mice by determ...

journal_title：Pharmaceutical biology

authors： de Oliveira TM,de Carvalho RB,da Costa IH,de Oliveira GA,de Souza AA,de Lima SG,de Freitas RM

更新日期：2015-03-01 00:00:00

abstract：:In this study, branchlets, fruit, or bark of Taxus baccata. L. as well as branchlets or fruits of two other species of Iranian conifers, namely, Platycladus orientalis. France and Cupressus sempervirens. L. var. horizentalis. (Mill) Gunde were collected, identified, and the cytotoxic effects of hydroalcoholic extracts...

journal_title：Pharmaceutical biology

authors： Emami SA,Sadeghi-Aliabadi H,Saeidi M,Jafarian A

更新日期：2005-01-01 00:00:00

abstract：CONTEXT:1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines. OBJECTIVE:To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of 1 ...

journal_title：Pharmaceutical biology

authors： Sun J,Jiang T,Xu W,Feng Z,Quan X,Leng P,Sun W,Zhao J,Jing F,Li J

更新日期：2019-12-01 00:00:00

abstract：CONTEXT:Silymarin (SM) is extracted from milk thistle Silybum marianum L. [Asteraceae (Compositae)] and known for antioxidative and anti-inflammatory effects. OBJECTIVE:The potential antidepressant-like effect of acute SM and possible involvement of nitric oxide (NO) were determined in male mice. MATERIAL AND METHODS...

journal_title：Pharmaceutical biology

authors： Khoshnoodi M,Fakhraei N,Dehpour AR

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:Diabetes mellitus is characterized by oxidative stress, which in turn induces endothelial dysfunction. As a potent antioxidant compound, lycopene might rescue diabetic endothelial dysfunction by reducing oxidative stress. OBJECTIVE:The present study investigated whether lycopene could lower oxidative stress an...

journal_title：Pharmaceutical biology

authors： Zhu J,Wang CG,Xu YG

更新日期：2011-11-01 00:00:00

abstract：CONTEXT:Ginger has been used commonly in the traditional system of medicine for the treatment of respiratory disorders. OBJECTIVE:The present study investigates the immunosuppressive activity of ginger by using the mouse model of ovalbumin-induced allergic asthma. MATERIALS AND METHODS:Treatment with ethanol extract ...

journal_title：Pharmaceutical biology

authors： Khan AM,Shahzad M,Raza Asim MB,Imran M,Shabbir A

更新日期：2015-03-01 00:00:00

abstract：CONTEXT:Calotropis procera (Ait.) R. Br. (Asclepiadaceae), Ficus elastica Roxb. (Moraceae) and Zingiber officinale Roscoe (Zingiberaceae) have been traditionally used to treat many diseases. OBJECTIVE:The antischistosomal activity of these plant extracts was evaluated against Schistosoma mansoni. MATERIALS AND METHOD...

journal_title：Pharmaceutical biology

authors： Seif el-Din SH,El-Lakkany NM,Mohamed MA,Hamed MM,Sterner O,Botros SS

更新日期：2014-02-01 00:00:00

abstract：CONTEXT:Tranexamic acid is commonly used for curing abnormal bleeding in a variety of diseases. In a previous study, 12 different tetrahydro-2H-1,3,5-thiadiazine derivatives were synthesized from the amine group of tranexamic acid. Their antifibrinolytic and antimicrobial activities were compared with tranexamic acid. ...

journal_title：Pharmaceutical biology

authors： Avuloğlu-Yılmaz E,Yüzbaşıoğlu D,Özçelik AB,Ersan S,Ünal F

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). OBJECTIVE:TPN was assessed for its antinociceptive activity in rodents. MATERIALS AND METHODS:The antinociceptive effect of TPN was examined using the acetic acid writhing reflex,...

journal_title：Pharmaceutical biology

authors： Quintans-Júnior LJ,Oliveira MG,Santana MF,Santana MT,Guimarães AG,Siqueira JS,De Sousa DP,Almeida RN

更新日期：2011-06-01 00:00:00

abstract：:Context: Cisplatin-based chemotherapy was widely used in treating human malignancies. However, side effects and chemoresistance remains the major obstacle.Objective: To verify whether natural borneol (NB) can enhance cisplatin-induced glioma cell apoptosis and explore the mechanism.Materials and methods: Cytotoxicity ...

journal_title：Pharmaceutical biology

authors： Cao WQ,Zhai XQ,Ma JW,Fu XQ,Zhao BS,Zhang P,Fu XY

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Lycopene is a phytonutrient under considerable investigation for its antioxidant benefits in treating diseases like cancer, cardiovascular diseases, osteoporosis and diabetes. OBJECTIVE:This study explores the effect of lycopene against oxidative damage during experimental hepatitis, induced by D-galactosamine...

journal_title：Pharmaceutical biology

authors： Sheik Abdulazeez S,Thiruvengadam D

更新日期：2013-12-01 00:00:00

abstract：CONTEXT:Salvicine is a pharmacologically active derivative from Chinese medicinal plant Salvia prionitis Hance (Labiatae). It has been reported that salvicine inactivates β1 integrin and inhibits integrin-mediated cell adhesion to fibronectin. Given the emerging correlation between integrins and angiogenesis, we propos...

journal_title：Pharmaceutical biology

authors： Zhang Y,Wang L,Chen Y,Qing C

更新日期：2013-08-01 00:00:00

abstract：CONTEXT:Despite phytochemical studies of Agrimonia pilosa Ledeb. (Rosaceae), the antidiabetic effects of this plant are unknown. OBJECTIVE:This study characterizes the isolated compounds from the aerial parts of A. pilosa and evaluates their PTP1B and α-glucosidase inhibitory properties. MATERIALS AND METHODS:Ethanol...

journal_title：Pharmaceutical biology

authors： Na B,Nguyen PH,Zhao BT,Vo QH,Min BS,Woo MH

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Seaweeds of the genera Turbinaria and Padina have long been used as food and in traditional medicine for treating several diseases. OBJECTIVE:The current study determines the protective efficacy of the brown seaweeds Turbinaria ornata (Turner) J. Agardh (Sargassaceae) and Padina pavonia (Linnaeus) J.V. Lamouro...

journal_title：Pharmaceutical biology

authors： Abdella EM,Mahmoud AM,El-Derby AM

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities. OBJECTIVE:The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicit...

journal_title：Pharmaceutical biology

authors： Al-Ashaal HA,El-Sheltawy ST

更新日期：2011-03-01 00:00:00

abstract：CONTEXT:Carissa edulis Vahl (Apocynaceae) is used in Nigerian folk medicine to manage a plethora of diseases including epilepsy, cancer, and inflammation; its efficacy is widely acclaimed among communities of northern Nigeria. OBJECTIVE:This study establishes anticonvulsant activities of aqueous fraction of ethanol ro...

journal_title：Pharmaceutical biology

authors： Ya'u J,Yaro AH,Malami S,Musa MA,Abubakar A,Yahaya SM,Chindo BA,Anuka JA,Hussaini IM

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Sepsis continues to be a significant problem for critical care patients. OBJECTIVE:To evaluate the protective effects of IgM-enriched immunoglobulin and erythropoietin on pulmonary and small intestine tissues in a rat model of intra-abdominal sepsis induced via the cecal ligation and puncture (CLP) method. MA...

journal_title：Pharmaceutical biology

authors： Ates I,Dogan N,Aksoy M,Halıcı Z,Gündogdu C,Keles MS

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Glycyrrhiza glabra L. (Febaceae) has been widely used in traditional medicine and scientifically explored for its anticonvulsant and memory improving potential. OBJECTIVE:The objective of this study is to investigate the effect of flavonoid rich fraction of G. glabra root extract against phenytoin-induced cogn...

journal_title：Pharmaceutical biology

authors： Singh P,Singh D,Goel RK

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:Safranal (SAF) is verified to have potential effects in promoting nerve growth. OBJECTIVES:This study verifies the role of SAF in promoting dopaminergic neurons growth in vitro and in vivo. MATERIAL AND METHODS:Rat neural stem cells (NSC) were treated with 1, 20, or 100 ng/mL of SAF, and the expression levels...

journal_title：Pharmaceutical biology

authors： Zhao Y,Xi G

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:The biotransformation of lilial results in an acid that is used in the dairy industry, in perfumery, as an intermediate in the manufacture of pharmaceuticals and cosmetics, and as a food additive for enhancing taste. OBJECTIVE:This study investigates the biotransformation of lilial by Staphylococcus aureus and...

journal_title：Pharmaceutical biology

authors： Esmaeili A,Afshari S,Esmaeili D

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Commiphora myrrha (Burseraceae), a shrub resembling a small tree, has been used for several centuries for the treatment of various diseases. OBJECTIVE:This study investigates the hepatoprotective activity of C. myrrha ethanol extract against d-galactosamine/lipopolysaccharide (d-GalN/LPS)-induced acute hepatic...

journal_title：Pharmaceutical biology

authors： Ahmad A,Raish M,Ganaie MA,Ahmad SR,Mohsin K,Al-Jenoobi FI,Al-Mohizea AM,Alkharfy KM

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Vicenin-1, a flavonol glycoside, has potent platelet aggregation inhibition, antioxidant, radioprotectants and anti-inflammatory activities. OBJECTIVE:To establish a rapid, simple, precise and sensitive high-performance liquid chromatography (HPLC) method for determination of vicenin-1 in rat plasma, and to in...

journal_title：Pharmaceutical biology

authors： Kandhare AD,Bodhankar SL,Mohan V,Thakurdesai PA

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:To date, there are no reports to validate the Indian traditional and folklore claims of Artemisia maderaspatana L. (syn. Grangea maderaspatana L.) (Asteraceae) for the treatment of Alzheimer's disease. OBJECTIVE:The present study characterizes the volatile components (non-polar compounds) of A. maderaspatana a...

journal_title：Pharmaceutical biology

authors： Jyotshna,Srivastava N,Singh B,Chanda D,Shanker K

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Tagetes patula L. is one of the French marigold group of the Asteraceae family. It is recognized in folklore for its medicinal and pesticidal properties. OBJECTIVE:In search of more effective, but non-toxic compounds with antioxidative potential led to the bioassay guided isolation studies on the extracts of T...

journal_title：Pharmaceutical biology

authors： Faizi S,Dar A,Siddiqi H,Naqvi S,Naz A,Bano S,Lubna

更新日期：2011-05-01 00:00:00

abstract：CONTEXT:(-)-α-Bisabolol (BISA) is a sesquiterpene alcohol widely used as scent in cosmetic preparations, perfumes, shampoos, toilet soaps and other toiletries with potential for use in the pharmaceutical area. OBJECTIVE:To evaluate the corneal antinociceptive efficacy of BISA and to analyze the best solubilizing agent...

journal_title：Pharmaceutical biology

authors： Teixeira GF,Costa FN,Campos AR

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Fructus Meliae toosendan extracts (FMTE) have a good therapeutic effect on coccidiosis, but there is no relevant research on its prophylactic effect on coccidiosis. OBJECTIVE:This study comprehensively evaluates the anticoccidial effect of FMTE. MATERIALS AND METHODS:In vitro, the unsporulated oocysts were tr...

journal_title：Pharmaceutical biology

authors： Yong T,Chen M,Li Y,Song X,Huang Y,Chen Y,Jia R,Zou Y,Li L,Yin L,He C,Lv C,Liang X,Ye G,Yin Z

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Dexamethasone (DXM) has an anti-immunoinflammatory effect, and is often used in acute kidney injury (AKI). However, the effects of DXM on albumin (ALB) have not been fully studied. OBJECTIVE:To investigate the effects of DXM on ALB production and renal function. MATERIALS AND METHODS:Male Wistar rats were div...

journal_title：Pharmaceutical biology

authors： Gong Q,Yin J,Wang M,He L,Lei F,Luo Y,Yang S,Feng Y,Li J,Du L

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Schizophrenia is a chronic disabling psychiatric disorder affecting 1% of the population worldwide. Due to the adverse effects of available antipsychotic medications, recent investigations have focused on the search for well-tolerated, safe molecules from natural resources to control the severity and progressio...

journal_title：Pharmaceutical biology

authors： Chatterjee M,Verma R,Kumari R,Singh S,Verma AK,Dwivedi AK,Palit G

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Anemarsaponin BII is one of the most active saponins isolated from Anemarrhena asphodeloides Bunge (Asparagaceae), a commonly used Chinese traditional paediatric medicine. OBJECTIVE:This study investigates the effects of anemarsaponin BII on the activity of CYP450s to provide more guidance for the clinical use...

journal_title：Pharmaceutical biology

authors： Wang M,Jiang W,Zhou J,Xue X,Yin C

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant. Its roots are used as the famous traditional Chinese medicine Huang-Qin, which is recorded in Chinese Pharmacopoeia, European Pharmacopoeia, and British Pharmacopoeia. OBJECTIVE:This review comprehensively summarizes research progress in ...

journal_title：Pharmaceutical biology

authors： Wang ZL,Wang S,Kuang Y,Hu ZM,Qiao X,Ye M

更新日期：2018-12-01 00:00:00