Abstract:
CONTEXT:The biotransformation of lilial results in an acid that is used in the dairy industry, in perfumery, as an intermediate in the manufacture of pharmaceuticals and cosmetics, and as a food additive for enhancing taste. OBJECTIVE:This study investigates the biotransformation of lilial by Staphylococcus aureus and Staphylococcus epidermidis, two bacterial species isolated from human skin. MATERIALS AND METHODS:Both species of Staphylococcus were isolated in samples taken from the skin of individuals living in a rural area of Iran. The pH of the culture medium was optimized, and after culturing the microorganisms, the bacteria were added to a flask containing a nutrient broth and incubated for several hours. The flasks of bacteria were combined with lilial, and various biochemical tests and diagnostics were performed, including Fourier transform infrared spectroscopy (FT-IR), ultraviolet-visible spectrophotometry (UV-Vis), and gas chromatography-mass spectroscopy (GC-MS). RESULTS:The S. aureus produced isobutyric acid (2-methylpropanoic acid) after 72 h (71% of the total products yielded during biotransformation), whereas the S. epidermidis produced terpenoid alcoholic media after 24 h (90% of total products obtained). DISCUSSION AND CONCLUSION:The results obtained indicate that biotransformation of lilial by S. aureus is more desirable than by S. epidermidis due to the highly efficient production of a single product. Bourgeonal and liliol were two toxic compounds produced during biotransformation, which indicates that the use of lilial in cosmetics can be harmful to the skin.
journal_name
Pharm Bioljournal_title
Pharmaceutical biologyauthors
Esmaeili A,Afshari S,Esmaeili Ddoi
10.3109/13880209.2015.1005755subject
Has Abstractpub_date
2015-01-01 00:00:00pages
1768-73issue
12eissn
1388-0209issn
1744-5116journal_volume
53pub_type
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.1080/13880209.2018.1501705
更新日期:2018-12-01 00:00:00
abstract:UNLABELLED:CONTEXT. Huperzia saururus (Lam.) Trevis. (Lycopodiaceae), an autochthonous plant species in Argentina, is used as a memory improver in traditional medicine. It was studied for this reason and the purified alkaloid extract did show significant activity on learning and memory. The species is mostly consumed i...
journal_title:Pharmaceutical biology
pub_type: 杂志文章
doi:10.3109/13880209.2013.784921
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更新日期:2019-12-01 00:00:00
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journal_title:Pharmaceutical biology
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journal_title:Pharmaceutical biology
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更新日期:2014-03-01 00:00:00
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journal_title:Pharmaceutical biology
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更新日期:2010-07-01 00:00:00
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更新日期:2011-11-01 00:00:00
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更新日期:2016-09-01 00:00:00
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doi:10.3109/13880209.2012.749924
更新日期:2013-05-01 00:00:00
abstract:CONTEXT:Brassicaceae plants are associated with protection against cancers due to their glucosinolate contents. OBJECTIVES:We investigate fresh leaves, roots and ripe seeds of Lobularia libyca (Viv.) C.F.W. Meissn. (Brassicaceae) to identify their glucosinolate constituents, antimicrobial and cytotoxic activities Mate...
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更新日期:2016-12-01 00:00:00
abstract::Context The underground edible tuber of Dioscorea alata L. (Dioscoreaceae) is a functional food with high nutritive value and therapeutic potential. The tuber is known to possess anti-inflammatory properties in traditional medicine. Objective The present study explores the anti-inflammatory activity and standardisatio...
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更新日期:2016-08-01 00:00:00
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doi:10.3109/13880209.2013.877492
更新日期:2014-09-01 00:00:00
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更新日期:2012-04-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章,评审
doi:10.3109/13880209.2011.558515
更新日期:2011-09-01 00:00:00
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更新日期:2016-11-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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更新日期:2020-12-01 00:00:00
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更新日期:2020-12-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2016-10-01 00:00:00
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更新日期:2013-02-01 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
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更新日期:2013-11-05 00:00:00
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journal_title:Pharmaceutical biology
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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更新日期:2016-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-12-01 00:00:00