Antioxidant, anti-collagenase and anti-elastase activities of Phyllanthus emblica, Manilkara zapota and silymarin: an in vitro comparative study for anti-aging applications.

abstract：UNLABELLED:Context Murraya paniculata (L.) Jack (Rutaceae), Qianlixiang in Chinese, is distributed in China. As an important traditional Chinese medicine (TCM), it demonstrates many bioactivities, such as febrifuge, astringent, anti-dysenteric, and tonic. OBJECTIVE:The objective of this study is to evaluate the anti-i...

journal_title：Pharmaceutical biology

authors： Wu J,Liu K,Shi X

更新日期：2016-01-01 00:00:00

abstract：:Context Previous studies have shown that Scutellariae Radix, the dried root of Scutellaria baicalensis Georgi (Labiatae), has a certain inhibitory effect on P-glycoprotein (P-gp), but the effects of its main active constituents on P-gp are still ambiguous. Objectives In vitro studies were performed to investigate the ...

journal_title：Pharmaceutical biology

authors： Miao Q,Wang Z,Zhang Y,Miao P,Zhao Y,Zhang Y,Ma S

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:Glutathione reductase (GR, NADPH:oxidized glutathione oxidoreductase, E.C 1.6.4.2) is a flavoprotein that catalyzes the NADPH-dependent reduction of oxidized glutathione (GSSG). GR is a crucial enzyme in the antioxidant system by maintaining reduced glutathione (GSH). Glucose 6-phosphate dehydrogenase (G6PD, gl...

journal_title：Pharmaceutical biology

authors： Tandogan B,Kuruüzüm-Uz A,Sengezer C,Güvenalp Z,Demirezer LÖ,Ulusu NN

更新日期：2011-06-01 00:00:00

abstract：:Context Syzygium densiflorum Wall. ex Wight & Arn (Myrtaceae) has been traditionally used by local tribes of the Nilgiris, Tamil Nadu, India, for the treatment of diabetes, however, no definitive experimental studies are available. Objective This study investigates the antidiabetic, antihyperlipidaemic and antioxidant...

journal_title：Pharmaceutical biology

authors： Krishnasamy G,Muthusamy K,Chellappan DR,Subbiah N

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:Chrysanthemum boreale Makino (Compositae) (CBM) is a traditional medicine that has been used for the prevention or treatment of various disorders; it has various properties including antioxidation, anti-inflammation, and antitumor. OBJECTIVE:The present study was designed to explore the in vitro effect of CBM ...

journal_title：Pharmaceutical biology

authors： Kim DY,Won KJ,Yoon MS,Yu HJ,Park JH,Kim B,Lee HM

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:The roots of Phytolacca americana L. (Phytolaccaceae) may be toxic. Despite heated controversy over the toxic compounds of P. americana, especially esculentosides, relevant studies remain scarce. OBJECTIVE:The objective of this study is to screen the toxic fractions and compounds of P. americana, to determine ...

journal_title：Pharmaceutical biology

authors： Yu H,Gong L,Wang X,Wu H,Zhao T,Wang K,Cui X,Chen L

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Urtica dioica L. (Urticaceae), stinging nettle, has been employed as a folklore remedy for a wide spectrum of ailments, including urinary disorders, prostatic hyperplasia, and liver diseases. It has been also used traditionally for cancer treatment. OBJECT:To evaluate the potential chemopreventive properties o...

journal_title：Pharmaceutical biology

authors： Di Sotto A,Mazzanti G,Savickiene N,Staršelskytė R,Baksenskaite V,Di Giacomo S,Vitalone A

更新日期：2015-06-01 00:00:00

abstract：:Different extracts from the stem bark of Berberis asiatica L. , a plant traditionally used to hasten the process of wound healing, and the alkaloid fractions derived from the commonly used aqueous extract, were tested for their putative antimicrobial activity against a battery of microorganisms by disk diffusion and a...

journal_title：Pharmaceutical biology

authors： Bhandari DK,Nath G,Ray AB,Tewari PV

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Prunella vulgaris L. (Labiatae) is a perennial plant common in China and Europe and is rich in rosmarinic acid (RA), ursolic acid (UA), and oleanolic acid (OA). The dried spica of P. vulgaris has been used as traditional medicine in China for over a hundred years. To our best knowledge, no study has been conduc...

journal_title：Pharmaceutical biology

authors： Chen Y,Guo Q,Zhu Z,Zhang L

更新日期：2012-09-01 00:00:00

abstract：CONTEXT:Silymarin (SM) is extracted from milk thistle Silybum marianum L. [Asteraceae (Compositae)] and known for antioxidative and anti-inflammatory effects. OBJECTIVE:The potential antidepressant-like effect of acute SM and possible involvement of nitric oxide (NO) were determined in male mice. MATERIAL AND METHODS...

journal_title：Pharmaceutical biology

authors： Khoshnoodi M,Fakhraei N,Dehpour AR

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:Alismatis rhizome (RA) (Water Plantain Family, also called "Zexie" in Chinese), one of the commonly used components of traditional Chinese medicines, is derived from the dried rhizomes of Alisma orientalis (Sam.) Juzep. (Alismataceae). OBJECTIVE:This study explores the RA influences on rat cytochrome P450 (CYP...

journal_title：Pharmaceutical biology

authors： Huang Y,Zheng SL,Xu ZS,Hou Y

更新日期：2014-06-01 00:00:00

abstract：:The effect of Celastrus paniculatus Willd. (Celastraceae) seed aqueous extract on learning and memory was studied using elevated plus maze and passive avoidance test (sodium nitrite induced amnesia rodent model). The aqueous seed extract was administered orally in two different doses to rats (350 and 1050 mg/kg) and t...

journal_title：Pharmaceutical biology

authors： Bhanumathy M,Harish MS,Shivaprasad HN,Sushma G

更新日期：2010-03-01 00:00:00

abstract：CONTEXT:The pharmaceutical alkaloid huperzine A (HupA), currently used in herbal supplements and medicines worldwide, is predominantly sourced from the Chinese lycopod Huperzia serrata (Thunb. ex Murray) Trev. (Lycopodiaceae), which on average contains only 0.08 mg HupA g(-1) dry weight, and is experiencing a rapid dec...

journal_title：Pharmaceutical biology

authors： Lim WH,Goodger JQ,Field AR,Holtum JA,Woodrow IE

更新日期：2010-09-01 00:00:00

abstract：CONTEXT:Angelica sinensis (Oliv.) Diels (Apiaceae) (syn. Angelica polymorpha Maxim var. sinensis Oliver) processed with yellow rice wine (WAS) has a blood-supplementing effect. OBJECTIVE:To establish an optimal technology for preparing water decoction of WAS (WASD), and screen blood-supplementing fractions. MATERIALS...

journal_title：Pharmaceutical biology

authors： Ji P,Li C,Wei Y,Wu F,Liu S,Hua Y,Yao W,Zhang X,Yuan Z,Wen Y

更新日期：2020-12-01 00:00:00

abstract：:Rhinacanthus nasutus (L.) Kurz (Acanthaceae) has long been used in Thai traditional medicine for treatment of tinea versicolor, ringworm, pruritic rash, and abscess. The active constituents are known as a group of naphthoquinone esters, rhinacanthins. This work focused on establishment of R. nasutus root cultures and ...

journal_title：Pharmaceutical biology

authors： Panichayupakaranant P,Meerungrueang W

更新日期：2010-11-01 00:00:00

abstract：CONTEXT:Red ginseng (heat-processed Panax ginseng) is a well-known alternative medicine with pharmacological antidiabetic activity. It exerts pharmacological effects through the transformation of saponin into metabolites by the intestinal microbiota. Given that intestinal conditions and intestinal microflora vary among...

journal_title：Pharmaceutical biology

authors： Jang SH,Park J,Kim SH,Choi KM,Ko ES,Cha JD,Lee YR,Jang H,Jang YS

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Clerodendrum viscosum Vent. (Verbenaceae) is a shrub, widely used amongst the natives of India against various diseases. OBJECTIVE:Crude extract of the plant was tested in vitro on a tapeworm Raillietina tetragona Molin (Davaineidae) to evaluate its potential anthelmintic efficacy and ultrastructural changes i...

journal_title：Pharmaceutical biology

authors： Nandi S,Ukil B,Roy S,Kundu S,Lyndem LM

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Ginger [Zingiber officinale Roscoe. (Zingiberaceae)] has been universally used as a spice as well as for its health benefits. OBJECTIVE:The present study evaluates the protective effect of the standardized extract of ginger against isoproterenol (ISO)-induced myocardial infarction (MI) in rats. MATERIALS AND ...

journal_title：Pharmaceutical biology

authors： Amran AZ,Jantan I,Dianita R,Buang F

更新日期：2015-01-01 00:00:00

abstract：:Context: Curcumin, a polyphenolic compound extracted from the rhizome of the tropical plant Curcuma longa L. (Zingiberaceae), has been considered as a cancer chemopreventive drug by American National Cancer Institute.Objective: To examine the effect of curcumin on acute monocytic leukaemia SHI-1 cells in vivo.Material...

journal_title：Pharmaceutical biology

authors： Zhu G,Shen Q,Jiang H,Ji O,Zhu L,Zhang L

更新日期：2020-12-01 00:00:00

abstract：:The effects of isosaline extracts of Tetrapleura tetrapetra and Olax subscorpioides were investigated in albino rats. The treatment of rats with these extracts resulted in an increase in the activities of serum alanine aminotransferase, liver aspartate aminotransferase, alanine aminotransferase, acid phosphatase and a...

journal_title：Pharmaceutical biology

authors： Olagunju JA,Oyedapo OO,Onasanya BA,Osoba OO,Adebanjo OO,Eweje O,Shodeinde AB

更新日期：2000-01-01 00:00:00

abstract：:Heliopsis longipes S.F. Blake (Asteraceae: Heliantheae) (chilcuague) is used in Mexican traditional medicine against parasites and to alleviate tooth and muscle pains. Its biocide effect has already been experimentally demonstrated; however, its analgesic action and its action on the nervous system (NS) have not been ...

journal_title：Pharmaceutical biology

authors： Cilia-López VG,Juárez-Flores BI,Aguirre-Rivera JR,Reyes-Agüero JA

更新日期：2010-02-01 00:00:00

abstract：CONTEXT:Phytochemical and pharmacological data on Ducrosia anethifolia (DC.) Boiss. (Apiaceae), an Iranian medicinal plant, are scarce; however, furocoumarins are characteristic compounds of D. anethifolia. OBJECTIVE:Our experiments identify the secondary metabolites of D. anethifolia and assess their antitumor and an...

journal_title：Pharmaceutical biology

authors： Mottaghipisheh J,Nové M,Spengler G,Kúsz N,Hohmann J,Csupor D

更新日期：2018-12-01 00:00:00

abstract：:Essential oil compositions and antioxidant potentials of fourteen ethanol (75%) root extracts prepared from twelve taxa of the genus Paeonia (Paeoniaceae), including P. arietina Anders., P. daurica Andrews, P. xkayae N. Ozhatay, P. kesrouanensis Thiéb., P. mascula (L.) Miller subsp. arasicola G. Kaynak, ö. Yilmaz & R....

journal_title：Pharmaceutical biology

authors： Orhan I,Demirci B,Omar I,Siddiqui H,Kaya E,Choudhary MI,Ecevit-Genç G,Ozhatay N,Sener B,Başer KH

更新日期：2010-01-01 00:00:00

abstract：CONTEXT:Seaweeds of the genera Turbinaria and Padina have long been used as food and in traditional medicine for treating several diseases. OBJECTIVE:The current study determines the protective efficacy of the brown seaweeds Turbinaria ornata (Turner) J. Agardh (Sargassaceae) and Padina pavonia (Linnaeus) J.V. Lamouro...

journal_title：Pharmaceutical biology

authors： Abdella EM,Mahmoud AM,El-Derby AM

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Calotropis procera (Ait.) R. Br. (Asclepiadaceae), Ficus elastica Roxb. (Moraceae) and Zingiber officinale Roscoe (Zingiberaceae) have been traditionally used to treat many diseases. OBJECTIVE:The antischistosomal activity of these plant extracts was evaluated against Schistosoma mansoni. MATERIALS AND METHOD...

journal_title：Pharmaceutical biology

authors： Seif el-Din SH,El-Lakkany NM,Mohamed MA,Hamed MM,Sterner O,Botros SS

更新日期：2014-02-01 00:00:00

abstract：CONTEXT:Buchenavia tetraphylla (Aubl.) RA Howard (Combretaceae: Combretoideae) is an ethnomedicinal plant with reported antifungal action. OBJECTIVE:This study evaluates the antimicrobial activity of B. tetraphylla leaf extracts against clinical isolates of Candida albicans. The morphological alterations, combinatory ...

journal_title：Pharmaceutical biology

authors： Cavalcanti Filho JR,Silva TF,Nobre WQ,Oliveira de Souza LI,Silva E Silva Figueiredo CS,Figueiredo RC,de Gusmão NB,Silva MV,Nascimento da Silva LC,Correia MT

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:α-Terpineol (TPN) is a monoterpenoid alcohol present in the essential oils of several species of the Eucalyptus genus (Myrtaceae). OBJECTIVE:TPN was assessed for its antinociceptive activity in rodents. MATERIALS AND METHODS:The antinociceptive effect of TPN was examined using the acetic acid writhing reflex,...

journal_title：Pharmaceutical biology

authors： Quintans-Júnior LJ,Oliveira MG,Santana MF,Santana MT,Guimarães AG,Siqueira JS,De Sousa DP,Almeida RN

更新日期：2011-06-01 00:00:00

abstract：CONTEXT:Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities. OBJECTIVE:The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicit...

journal_title：Pharmaceutical biology

authors： Al-Ashaal HA,El-Sheltawy ST

更新日期：2011-03-01 00:00:00

abstract：CONTEXT:The poor prognostic outcome of breast cancer is largely due to its resistance to cancer therapies. Development of therapeutic agents that can inhibit growth and induce apoptosis in breast cancer cells can help solve the problem. Emodin is an active anthraquinone that has been reported to have diverse biological...

journal_title：Pharmaceutical biology

authors： Li WY,Chan RY,Yu PH,Chan SW

更新日期：2013-09-01 00:00:00

abstract：CONTEXT:Hyperthermia causes detrimental effects on the testes leading to fertility problems. Mallotus roxbhurghianus Muell. Arg. (Euphorbiaceae) is used in traditional medicine and possesses antioxidant property. However, the mechanisms remain unknown in the context of alleviative action of M. roxburghianus against hea...

journal_title：Pharmaceutical biology

authors： Kumar Roy V,Marak TR,Gurusubramanian G

更新日期：2016-01-01 00:00:00