Effects of Alismatis rhizome on rat cytochrome P450 enzymes.

abstract：CONTEXT:Propranolol, atenolol, and ICI118,551 are non-selective β-adrenergic receptor (AR), β1-AR, and β2-AR antagonists, respectively. OBJECTIVE:We investigated the efficacy of propranolol, atenolol, and ICI118,551 on proliferation, migration, and invasion of non-stimulated breast (MCF7), colon (HT-29), and hepatocel...

journal_title：Pharmaceutical biology

authors： Işeri OD,Sahin FI,Terzi YK,Yurtcu E,Erdem SR,Sarialioglu F

更新日期：2014-11-01 00:00:00

abstract：CONTEXT:Marine cyanobacteria offer a robust resource for natural products drug discovery due to the secondary metabolites they produce. OBJECTIVE:To identify novel cyanobacterial compounds that exhibit CNS psychoactive effects. MATERIALS AND METHODS:Cyanobacteria were collected from Las Perlas Archipelago, Panama and...

journal_title：Pharmaceutical biology

authors： Lax NC,Ahmed KT,Ignatz CM,Spadafora C,Kolber BJ,Tidgewell KJ

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Millettia barteri (Benth.) Dunn (Fabaceae) is an African medicinal plant used in folk medicine to treat many diseases. This species, as well as other Mellettia species, has been of interest to researchers because of their wide range of traditional uses. OBJECTIVE:Phytochemical, antimicrobial and 2,2-diphenyl-1...

journal_title：Pharmaceutical biology

authors： Havyarimana L,Ndendoung ST,Tamokou Jde D,Atchadé Ade T,Tanyi JM

更新日期：2012-02-01 00:00:00

abstract：CONTEXT:The application of bleomycin is limited due to its side effects including lung toxicity. Silymarin is a flavonoid complex isolated from milk thistle [Silybum marianum L. (Asteraceae)] which has been identified as an antioxidant and anti-inflammatory compound. OBJECTIVE:This study evaluates the effect of silyma...

journal_title：Pharmaceutical biology

authors： Razavi-Azarkhiavi K,Ali-Omrani M,Solgi R,Bagheri P,Haji-Noormohammadi M,Amani N,Sepand MR

更新日期：2014-10-01 00:00:00

abstract：CONTEXT:Lycopene is a phytonutrient under considerable investigation for its antioxidant benefits in treating diseases like cancer, cardiovascular diseases, osteoporosis and diabetes. OBJECTIVE:This study explores the effect of lycopene against oxidative damage during experimental hepatitis, induced by D-galactosamine...

journal_title：Pharmaceutical biology

authors： Sheik Abdulazeez S,Thiruvengadam D

更新日期：2013-12-01 00:00:00

abstract：CONTEXT:Tagetes patula L. is one of the French marigold group of the Asteraceae family. It is recognized in folklore for its medicinal and pesticidal properties. OBJECTIVE:In search of more effective, but non-toxic compounds with antioxidative potential led to the bioassay guided isolation studies on the extracts of T...

journal_title：Pharmaceutical biology

authors： Faizi S,Dar A,Siddiqi H,Naqvi S,Naz A,Bano S,Lubna

更新日期：2011-05-01 00:00:00

abstract：CONTEXT:Glycyrrhiza glabra L. (Febaceae) has been widely used in traditional medicine and scientifically explored for its anticonvulsant and memory improving potential. OBJECTIVE:The objective of this study is to investigate the effect of flavonoid rich fraction of G. glabra root extract against phenytoin-induced cogn...

journal_title：Pharmaceutical biology

authors： Singh P,Singh D,Goel RK

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:Angelica sinensis (Oliv.) Diels (Apiaceae) (syn. Angelica polymorpha Maxim var. sinensis Oliver) processed with yellow rice wine (WAS) has a blood-supplementing effect. OBJECTIVE:To establish an optimal technology for preparing water decoction of WAS (WASD), and screen blood-supplementing fractions. MATERIALS...

journal_title：Pharmaceutical biology

authors： Ji P,Li C,Wei Y,Wu F,Liu S,Hua Y,Yao W,Zhang X,Yuan Z,Wen Y

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Medical therapies for alcohol-induced liver disease are often difficult to handle and limited in efficacy. OBJECTIVE:In an attempt to find natural therapeutics, here, we investigate the preventive effect of persimmon vinegar (PV) and its fractions against alcohol-induced hepatic injury, in addition to the unde...

journal_title：Pharmaceutical biology

authors： Lee HM,Park MY,Kim J,Shin JH,Park KS,Kwon O

更新日期：2016-11-01 00:00:00

abstract：:Context: Puerarin and triptolide are sometimes used together for the treatment of disease in Chinese clinics; however, the drug-drug interaction between puerarin and triptolide is still unknown. Objective: This study investigates the effects of puerarin on the pharmacokinetics of triptolide in rats and clarifies its m...

journal_title：Pharmaceutical biology

authors： Wang Q,Wu Y,Xiang F,Feng Y,Li Z,Ding Y

更新日期：2019-12-01 00:00:00

abstract：CONTEXT:Vernonia amygdalina Del. (VA; Asteraceae or Compositae) is a small tree growing throughout tropical Africa. It is widely used for food and medicinal purposes by local people. It was reported that it had several qualities, including anticancer activity. OBJECTIVE:A sesquiterpene lactone, vernodalinol, was isola...

journal_title：Pharmaceutical biology

authors： Luo X,Jiang Y,Fronczek FR,Lin C,Izevbigie EB,Lee KS

更新日期：2011-05-01 00:00:00

abstract：CONTEXT:Brassicaceae plants are associated with protection against cancers due to their glucosinolate contents. OBJECTIVES:We investigate fresh leaves, roots and ripe seeds of Lobularia libyca (Viv.) C.F.W. Meissn. (Brassicaceae) to identify their glucosinolate constituents, antimicrobial and cytotoxic activities Mate...

journal_title：Pharmaceutical biology

authors： Al-Gendy AA,Nematallah KA,Zaghloul SS,Ayoub NA

更新日期：2016-12-01 00:00:00

abstract：CONTEXT:Glycosmis pentaphylla (Retz.) DC (Rutaceae) is a shrub, traditionally used to treat anemia, rheumatism, as an anthelmintic, febrifuge and vermifuge, for jaundice, and liver complaints. OBJECTIVE:This study evaluated the hepatoprotective activity of G. pentaphylla against paracetamol-induced hepatotoxicity in S...

journal_title：Pharmaceutical biology

authors： Nayak SS,Jain R,Sahoo AK

更新日期：2011-02-01 00:00:00

abstract：CONTEXT:Herbal therapies are used worldwide to treat health conditions. In Mexico, generations have used them to treat gingivitis, periodontitis, mouth infections, and discoloured teeth. However, few studies have collected scientific evidence on their effects. OBJECTIVE:This study aimed at searching and compiling scie...

journal_title：Pharmaceutical biology

authors： Cruz Martínez C,Diaz Gómez M,Oh MS

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:For years, natural products from microbes have been used as drugs. Endophytes are the most important fungi that produce many novel metabolites for potential use in pharmacology and agriculture. OBJECTIVE:The objective of the present study was to explore new endophytes for novel natural products. MATERIALS AND...

journal_title：Pharmaceutical biology

authors： Katoch M,Khajuria A,Sharma PR,Saxena AK

更新日期：2015-01-01 00:00:00

abstract：:2-Formyl-1-hydroxyanthraquinone, along with ten other known anthraquinones (1-hydroxy-2-methylanthraquinone, nordamnacanthal, damnacanthal, lucidin-?-methyl ether, rubiadin, rubiadin-1-methyl ether, soranjidiol, morindone, morindone-5-methyl ether and alizarin-1-methyl ether), isolated from the roots of Morinda ellipt...

journal_title：Pharmaceutical biology

authors： Ali AM,Ismail NH,Mackeen MM,Yazan LS,Mohamed SM,Ho AS,Lajis NH

更新日期：2000-01-01 00:00:00

abstract：CONTEXT:Solenostemon monostachyus P. Beauv (Lamiaceae) is an important herb used traditionally in the treatment of malaria, fever, and other diseases. OBJECTIVES:Antiplasmodial and antipyretic activities of S. monostachyus aerial extract were evaluated to ascertain the folkloric claim of its antimalarial and antipyret...

journal_title：Pharmaceutical biology

authors： Okokon J,Davis KA,Azare BA

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Withania (Solanaceae) species are known to be a rich source of withanolides, which have shown several biological properties. OBJECTIVE:To identify the compounds responsible for Withania adpressa Coss. antioxidant activity and further test them for their NF-κB inhibition and antiproliferative activity in multip...

journal_title：Pharmaceutical biology

authors： Ben Bakrim W,El Bouzidi L,Nuzillard JM,Cretton S,Saraux N,Monteillier A,Christen P,Cuendet M,Bekkouche K

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:Acrostichum aureumL. (Pteridaceae), a mangrove fern, has been used as a Bangladeshi traditional medicine for a variety of diseases including peptic ulcer. OBJECTIVE:Isolation and structural elucidation of cytotoxic secondary metabolites from the methanol extract of the aerial parts of A. aureum. MATERIALS AND...

journal_title：Pharmaceutical biology

authors： Uddin SJ,Grice D,Tiralongo E

更新日期：2012-10-01 00:00:00

abstract：:In the present study, the anxiolytic and sedative-hypnotic activities of polygalasaponins extracted from Polygala tenuifolia Willdenow (Polygalaceae) were determined in mice using hole-board, elevated plus maze, open field, and sodium pentobarbital-induced hypnosis tests. Moreover, the acute toxicity of polygalasaponi...

journal_title：Pharmaceutical biology

authors： Yao Y,Jia M,Wu JG,Zhang H,Sun LN,Chen WS,Rahman K

更新日期：2010-07-01 00:00:00

abstract：CONTEXT:Scrophularia genus (Scrophulariaceae) includes about 350 species commonly known as figwort. Many species of this genus grow wild in nature and have not been cultivated yet. However, some species are in danger of extinction. OBJECTIVE:This paper reviews the chemical compounds, biological activities and the ethn...

journal_title：Pharmaceutical biology

authors： Pasdaran A,Hamedi A

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Hypertrophic scarring, a common proliferative disorder of dermal fibroblasts, results from an overproduction of collagen and excessive deposition of extracellular matrix. Although the treatment with surgical excisions or steroid hormones can modify the symptoms, numerous treatment-related complications have als...

journal_title：Pharmaceutical biology

authors： Wu JG,Wei YJ,Ran X,Zhang H,Nian H,Qin LP

更新日期：2011-07-01 00:00:00

abstract：CONTEXT:Polygonum multiflorum is known as a medicinal plant. It has been used as a folk medicine which showed antioxidative property. OBJECTIVE:Protective effects of the water extracts (w/v:1/10) from fresh P. multiflorum (WEP) on carbon tetrachloride (CCl(4))-induced liver damage in rats were investigated. MATERIALS...

journal_title：Pharmaceutical biology

authors： Lee BH,Huang YY,Duh PD,Wu SC

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the aqueous extract from aerial parts of Artemisia copa Phil. (Asteraceae) administered orallyfor its psychopharmacological activities in several experimental models. METHODS:The extract was administered p.o. in Swiss albino mice and tested on pentobarbital-induced hypnosis, locomotor activity, e...

journal_title：Pharmaceutical biology

authors： Miño JH,Moscatelli V,Acevedo C,Ferraro G

更新日期：2010-12-01 00:00:00

abstract：CONTEXT:Salvia semiatrata Zucc. (Lamiaceae) is a species used as a tranquilizer and to relieve pain in folk medicine in Santiago Huauclilla, Oaxaca, Mexico. OBJECTIVE:To evaluate the antinociceptive and anxiolytic-like effects of S. semiatrata extracts and identify a bioactive metabolite. MATERIALS AND METHODS:The ex...

journal_title：Pharmaceutical biology

authors： Ortiz-Mendoza N,Zavala-Ocampo LM,Martínez-Gordillo MJ,González-Trujano ME,Peña FAB,Rodríguez IJB,Chávez JAR,Dorazco-González A,Aguirre-Hernández E

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Ferulago angulata (Schlecht.) Boiss. (Apiaceae) (FASB) is used to treat liver diseases and has been used both as food and therapeutics by many cultures for thousands of years because of the natural antioxidant compounds. OBJECTIVE:This study determines antioxidant properties of FASB flowers, the levels of mine...

journal_title：Pharmaceutical biology

authors： Kiziltas H,Ekin S,Bayramoglu M,Akbas E,Oto G,Yildirim S,Ozgokce F

更新日期：2017-12-01 00:00:00

abstract：:Context: Fuzheng Huayu recipe (FZHY) combined with entecavir (ETV) is used to treat the cirrhosis caused by chronic hepatitis B (CHB) infection.Objective: To investigate the effect of FZHY on ETV pharmacokinetics under different conditions.Materials and methods: A model of liver fibrosis was created by intraperitoneal...

journal_title：Pharmaceutical biology

authors： Yang T,Zheng TH,Zhao Q,Liu W,Li SP,Tao YY,Wang CH,Liu CH

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Aloe has been used for the prevention and cure of various diseases and symptoms including burns, injuries, oedema and pain. OBJECTIVE:This study determines the specific inhibitory activity of matrix metalloproteinase (MMP)-9 induced by the low molecular-weight gel fraction of Aloe vera (L.) Burm.f. (lgfAv) on ...

journal_title：Pharmaceutical biology

authors： Park CH,Son HU,Yoo CY,Lee SH

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Ferula cupularis (Boiss.) Spalik et S. R. Downie (Apiaceae) is a common plant in Iran that grows in the foothills of Dena Mountain. In traditional folk medicine, this plant has different applications, but there are no studies proving their uses. OBJECTIVE:This study is the first attempt to investigate the chem...

journal_title：Pharmaceutical biology

authors： Alipour Z,Taheri P,Samadi N

更新日期：2015-04-01 00:00:00

abstract：CONTEXT:Rutin, a flavonoid commonly present in onions, apples and tea, has been suggested to have a variety of pharmacological activities, including immunomodulator, anti-inflammatory and antioxidant activities. OBJECTIVES:The present study was to examine the protective effects of rutin on gastric mucosal damage induc...

journal_title：Pharmaceutical biology

authors： Liu Y,Gou L,Fu X,Li S,Lan N,Yin X

更新日期：2013-07-01 00:00:00