The potential medicinal value of plants from Asteraceae family with antioxidant defense enzymes as biological targets.

abstract：CONTEXT:Arecoline is an effective constituent of Areca catechu L. (Arecaceae) with various pharmacological effects. However, investigations also revealed that long use of arecoline could arouse some oral diseases. OBJECTIVE:The present review gathers the fragmented information available in the literature (before 1 Oct...

journal_title：Pharmaceutical biology

authors： Liu YJ,Peng W,Hu MB,Xu M,Wu CJ

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Hydroxysafflor yellow A (HSYA) has been shown to have neuroprotective effects in cerebral infarction. However, its underlying roles in apoptosis and inflammation in Parkinson's disease (PD) are unknown. OBJECTIVE:The present study investigates the effects and underlying mechanisms of HSYA on dopaminergic (DA) ...

journal_title：Pharmaceutical biology

authors： Yang X,Li Y,Chen L,Xu M,Wu J,Zhang P,Nel D,Sun B

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Cucurbitacins are a group of triterpenoids that have a cucurbitane skeleton with a wide range of biological activities. OBJECTIVES:This study evaluated the anticancer properties of one cucurbitacin isolated from Cayaponia racemosa Cong. (Cucurbitaceae), 2β,3β,16α,20(R),25-pentahydroxy-22-oxocucurbita-5-en (1),...

journal_title：Pharmaceutical biology

authors： Militão GC,Dantas IN,Ferreira PM,Alves AP,Chaves DC,Monte FJ,Pessoa C,Odorico de Moraes M,Costa-Lotufo LV

更新日期：2012-12-01 00:00:00

abstract：CONTEXT:During the last few decades, the prevalence of obesity in the western world has dramatically increased with epidemic proportions. Hand in hand with this statistic, the incidences of obesity-linked diseases such as diabetes are increasing with pandemic rate. The search for novel drugs and nutritional interventio...

journal_title：Pharmaceutical biology

authors： Habtemariam S

更新日期：2012-12-01 00:00:00

abstract：CONTEXT: Despite the myriad uses of Annona senegalensis Pers. (Annonaceae) leaves in folklore medicine of Nigeria, the basis is yet to be substantiated by scientific investigations. OBJECTIVES: To investigate the antioxidant (in vitro and in vivo) and drug detoxification potential of aqueous extract of A. senegalensis...

journal_title：Pharmaceutical biology

authors： Ajboye TO,Yakubu MT,Salau AK,Oladiji AT,Akanji MA,Okogun JI

更新日期：2010-12-01 00:00:00

abstract：CONTEXT:Cranberry has numerous biological activities, including antioxidation, anticancer, cardioprotection, as well as treatment of urinary tract infection (UTI), attributed to abundant phenolic contents. OBJECTIVE:The current study focused on the effect of cranberry juice (CJ) on blue light exposed human retinal pig...

journal_title：Pharmaceutical biology

authors： Chang CH,Chiu HF,Han YC,Chen IH,Shen YC,Venkatakrishnan K,Wang CK

更新日期：2017-12-01 00:00:00

abstract：:Clitoria ternatea , commonly known as Shankpushpi, is widely used in the traditional Indian system of medicine as a brain tonic and is believed to promote memory and intelligence. We examined the effectiveness of alcoholic extracts of aerial and root parts of C. ternatea at 300 and 500 mg/kg doses orally in rats in at...

journal_title：Pharmaceutical biology

authors： Taranalli AD,Cheeramkuzhy TC

更新日期：2000-01-01 00:00:00

abstract：:The effects of isosaline extracts of Tetrapleura tetrapetra and Olax subscorpioides were investigated in albino rats. The treatment of rats with these extracts resulted in an increase in the activities of serum alanine aminotransferase, liver aspartate aminotransferase, alanine aminotransferase, acid phosphatase and a...

journal_title：Pharmaceutical biology

authors： Olagunju JA,Oyedapo OO,Onasanya BA,Osoba OO,Adebanjo OO,Eweje O,Shodeinde AB

更新日期：2000-01-01 00:00:00

abstract：:Proteins from Parkia speciosa Hassk. (Fabaceae) seeds were extracted and stepwise precipitated using ammonium sulfate. Proteins precipitated with 25% ammonium sulfate were separated by affinity chromatography on Affi-Gel Blue gel followed by protein liquid chromatography on Superdex 200. The protein Gj, which was iden...

journal_title：Pharmaceutical biology

authors： Chankhamjon K,Petsom A,Sawasdipuksa N,Sangvanich P

更新日期：2010-01-01 00:00:00

abstract：:Context Acetaminophen (APAP), also known as paracetamol and N-acetyl p-aminophenol, is one of the most frequently used drugs for analgesic and antipyretic purposes on a worldwide basis. It is safe and effective at recommended doses but has the potential for causing hepatotoxicity and acute liver failure (ALF) with ove...

journal_title：Pharmaceutical biology

authors： Eugenio-Pérez D,Montes de Oca-Solano HA,Pedraza-Chaverri J

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:The application of bleomycin is limited due to its side effects including lung toxicity. Silymarin is a flavonoid complex isolated from milk thistle [Silybum marianum L. (Asteraceae)] which has been identified as an antioxidant and anti-inflammatory compound. OBJECTIVE:This study evaluates the effect of silyma...

journal_title：Pharmaceutical biology

authors： Razavi-Azarkhiavi K,Ali-Omrani M,Solgi R,Bagheri P,Haji-Noormohammadi M,Amani N,Sepand MR

更新日期：2014-10-01 00:00:00

abstract：CONTEXT:Medical therapies for alcohol-induced liver disease are often difficult to handle and limited in efficacy. OBJECTIVE:In an attempt to find natural therapeutics, here, we investigate the preventive effect of persimmon vinegar (PV) and its fractions against alcohol-induced hepatic injury, in addition to the unde...

journal_title：Pharmaceutical biology

authors： Lee HM,Park MY,Kim J,Shin JH,Park KS,Kwon O

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:The roots of Alafia barteri Oliver (Apocynaceae), Combretum mucronatum Schumach (Combretaceae) and Capparis thonningii Schum (Capparaceae) are used in Traditional African Medicine to alleviate painful and inflammatory conditions. OBJECTIVE:This study investigated the analgesic and anti-inflammatory effects of ...

journal_title：Pharmaceutical biology

authors： Ishola IO,Agbaje EO,Adeyemi OO,Shukla R

更新日期：2014-09-01 00:00:00

abstract：:The effect of Celastrus paniculatus Willd. (Celastraceae) seed aqueous extract on learning and memory was studied using elevated plus maze and passive avoidance test (sodium nitrite induced amnesia rodent model). The aqueous seed extract was administered orally in two different doses to rats (350 and 1050 mg/kg) and t...

journal_title：Pharmaceutical biology

authors： Bhanumathy M,Harish MS,Shivaprasad HN,Sushma G

更新日期：2010-03-01 00:00:00

abstract：CONTEXT:2,7-Dihydroxy-3-methylanthraquinone (DDMN) is reported to have a remarkable anticancer activity against gastric cancer SGC-7901 cells. OBJECTIVE:The objective of this study is to study the anticancer effect and mechanism of DDMN on SGC-7901 cells. MATERIALS AND METHODS:The MTT assay was used to determine the ...

journal_title：Pharmaceutical biology

authors： Zhu H,Zheng Z,Zhang J,Liu X,Liu Y,Yang W,Liu Y,Zhang T,Zhao Y,Liu Y,Su X,Gu X

更新日期：2016-01-01 00:00:00

abstract：:Context:Mitrephora sirikitiae Weeras., Chalermglin & R.M.K. Saunders (Annonaceae) is a plant endemic to Thailand. Its constituents and their biological activities are unknown.Objective: Isolation and identification of the compounds in the leaves and stems of M. sirikitiae and determination of their cytotoxicity.Materi...

journal_title：Pharmaceutical biology

authors： Anantachoke N,Lovacharaporn D,Reutrakul V,Michel S,Gaslonde T,Piyachaturawat P,Suksen K,Prabpai S,Nuntasaen N

更新日期：2020-12-01 00:00:00

abstract：CONTEXT:Vernonia amygdalina Del. (VA; Asteraceae or Compositae) is a small tree growing throughout tropical Africa. It is widely used for food and medicinal purposes by local people. It was reported that it had several qualities, including anticancer activity. OBJECTIVE:A sesquiterpene lactone, vernodalinol, was isola...

journal_title：Pharmaceutical biology

authors： Luo X,Jiang Y,Fronczek FR,Lin C,Izevbigie EB,Lee KS

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the aqueous extract from aerial parts of Artemisia copa Phil. (Asteraceae) administered orallyfor its psychopharmacological activities in several experimental models. METHODS:The extract was administered p.o. in Swiss albino mice and tested on pentobarbital-induced hypnosis, locomotor activity, e...

journal_title：Pharmaceutical biology

authors： Miño JH,Moscatelli V,Acevedo C,Ferraro G

更新日期：2010-12-01 00:00:00

abstract：CONTEXT:Uncaria tomentosa D.C. (Rubiaceae) has several biological activities, including activity against resistant Candida strains. The synergistic interaction with terbinafine or fluconazole can be an important alternative to overcome this resistance. OBJECTIVES:The potential synergy between a water insoluble fractio...

journal_title：Pharmaceutical biology

authors： Moraes RC,Carvalho AR,Lana AJ,Kaiser S,Pippi B,Fuentefria AM,Ortega GG

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:The persistence of fascioliasis in many developing countries urges the search for simple, cheap, and effective substances. In this view, plants provide interesting molluscicidal activities thanks to the secondary metabolites they produce. The genus Solanum is known for its potent effect on vector snails. OBJEC...

journal_title：Pharmaceutical biology

authors： Njeh F,Feki H,Koubaa I,Hamed N,Damak M,Ayadi A,Hammami H,Mezghani-Jarraya R

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:Ethnobotanical claims of medicinal plants used in northern Maputaland are limited. Objectives To establish scientific validity for a selection of the plants used in Maputaland to treat skin diseases. MATERIALS AND METHODS:Aqueous and dichloromethane-methanol extracts were prepared from 37 plant species which w...

journal_title：Pharmaceutical biology

authors： Nciki S,Vuuren S,van Eyk A,de Wet H

更新日期：2016-11-01 00:00:00

abstract：CONTEXT:Neuropsychiatric disorders, like anxiety and depression, are global problems for clinical researchers in neurology. Recently, some authors have shown neuroprotective and anti-inflammatory effects of Scrophularia striata Boiss (Scrophulariaceae) extract in rodents. OBJECTIVE:The purpose of the current study was...

journal_title：Pharmaceutical biology

authors： Kosari-Nasab M,Babri S,Fatehi-Gharehlar L,Doosti MH,Pakzad S

更新日期：2013-05-01 00:00:00

abstract：CONTEXT:Safranal (SAF) is verified to have potential effects in promoting nerve growth. OBJECTIVES:This study verifies the role of SAF in promoting dopaminergic neurons growth in vitro and in vivo. MATERIAL AND METHODS:Rat neural stem cells (NSC) were treated with 1, 20, or 100 ng/mL of SAF, and the expression levels...

journal_title：Pharmaceutical biology

authors： Zhao Y,Xi G

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:The fruit of the Prunus mume Sieb. et Zucc (Rosaceae) is used as a health food or medicinal material in traditional herb medicine for a long time in Eastern Asian countries. OBJECTIVE:Our present study investigated the hypouricemic effect of the methanol extract from P. mume fruit (MPMF) in mice with potassium...

journal_title：Pharmaceutical biology

authors： Yi LT,Li J,Su DX,Dong JF,Li CF

更新日期：2012-11-01 00:00:00

abstract：CONTEXT:Salsola imbricata Forssk. (Chenopodiaceae) has folkloric repute for the treatment of various gastrointestinal and respiratory ailments. OBJECTIVE:The present study investigates spasmolytic and bronchorelaxant effects of S. imbricata. MATERIALS AND METHODS:The crude aqueous-ethanol extract of the aerial parts ...

journal_title：Pharmaceutical biology

authors： Aslam N,Janbaz KH

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Stachys guyoniana Noë ex. Batt. and Mentha aquatica L. are two Algerian Lamiaceae used in folk medicine. OBJECTIVE:To investigate their antioxidant, anticholinesterase and antibacterial activities. MATERIAL AND METHODS:n-Butanol (BESG), ethyl acetate (EESG) and chloroform (CESG) extracts of S. guyoniana and m...

journal_title：Pharmaceutical biology

authors： Ferhat M,Erol E,Beladjila KA,Çetintaş Y,Duru ME,Öztürk M,Kabouche A,Kabouche Z

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Psoralen and anastrozole are always used together for breast cancer patients in Chinese clinics. OBJECTIVE:This study investigates the effects of psoralen on the pharmacokinetics of anastrozole in rats and its potential mechanism. MATERIALS AND METHODS:The pharmacokinetics of orally administered anastrozole (...

journal_title：Pharmaceutical biology

authors： Zhang Y,Wu J,Zhou Y,Yin Y,Chen H

更新日期：2018-12-01 00:00:00

abstract：:Context The underground edible tuber of Dioscorea alata L. (Dioscoreaceae) is a functional food with high nutritive value and therapeutic potential. The tuber is known to possess anti-inflammatory properties in traditional medicine. Objective The present study explores the anti-inflammatory activity and standardisatio...

journal_title：Pharmaceutical biology

authors： Dey P,Roy Chowdhuri S,Sarkar MP,Chaudhuri TK

更新日期：2016-08-01 00:00:00

abstract：:Context Phyllanthus emblica L. (Euphorbiaceae) (amla), Manilkara zapota L.P. Royen (Sapotaceae) (sapota) and silymarin are reported to contain antioxidant effects. However, information on other biological activities relating to the anti-aging properties is limited. Objective To compare in vitro antioxidants, anti-coll...

journal_title：Pharmaceutical biology

authors： Pientaweeratch S,Panapisal V,Tansirikongkol A

更新日期：2016-09-01 00:00:00

abstract：CONTEXT:Withania (Solanaceae) species are known to be a rich source of withanolides, which have shown several biological properties. OBJECTIVE:To identify the compounds responsible for Withania adpressa Coss. antioxidant activity and further test them for their NF-κB inhibition and antiproliferative activity in multip...

journal_title：Pharmaceutical biology

authors： Ben Bakrim W,El Bouzidi L,Nuzillard JM,Cretton S,Saraux N,Monteillier A,Christen P,Cuendet M,Bekkouche K

更新日期：2018-12-01 00:00:00