Abstract:
:Hamster beta-tubulin (detected as a mutant subunit that confers Colcemid resistance) is either not expressed or is underexpressed in Chinese hamster-mouse somatic cell hybrids. This selectivity of tubulin expression suggests that a uniparental mouse spindle might preferentially engage mouse chromosomes and lead to loss of hamster chromosomes. However, the repression of hamster tubulin was found to have no bearing on the direction of chromosome segregation occurring in eight hybrids studied, some of which segregated predominantly mouse and other hamster chromosomes.
journal_name
Genomejournal_title
Genomeauthors
Zelesco PA,Graves JAdoi
10.1139/g87-090subject
Has Abstractpub_date
1987-08-01 00:00:00pages
528-31issue
4eissn
0831-2796issn
1480-3321journal_volume
29pub_type
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