Prior stress and susceptibility to stress ulcer.

Abstract:

:Rats were exposed to daily sessions of either restraint plus cold, forced exercise, or grid shock for one month and then subjected to the ulcerogenic effects of either supine restraint plus cold, or activity-stress. Chronic stress generally protected against stress ulcer but the protection depended on the degree of similarity between the pre-treatment stressor and the ulcerogenic procedure. Pre-treatment with restraint plus cold provided protection which applied not only to supine restraint plus cold but also generalized to activity-stress. Foot-shock pre-treatment did not significantly reduce restraint ulcer but it significantly exacerbated activity-stress ulcer.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Paré WP

doi

10.1016/0031-9384(86)90493-2

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

1155-9

issue

6

eissn

0031-9384

issn

1873-507X

pii

0031-9384(86)90493-2

journal_volume

36

pub_type

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