Nucleotide and deduced amino acid sequence of the influenza neuraminidase genes of two equine serotypes.

abstract：:Purified glycophorin (predominantly type A) from human erythrocytes was found to effectively inhibit reovirus hemagglutination (HA) in contrast to other glycoproteins such as fetuin or ovalbumin. Glycophorin was also a potent inhibitor of reovirus and protein sigma 1 binding to mouse L fibroblasts. Glycophorin pretrea...

journal_title：Virology

authors： Paul RW,Lee PW

更新日期：1987-07-01 00:00:00

abstract：:Marburg virus (MBGV), for which no vaccines or treatments currently exist, causes an acute hemorrhagic fever with a high mortality rate in humans. We previously showed that immunization with either killed MBGV or a glycoprotein (GP) subunit prevented lethal infection in guinea pigs. In the studies reported here, an RN...

journal_title：Virology

authors： Hevey M,Negley D,Pushko P,Smith J,Schmaljohn A

更新日期：1998-11-10 00:00:00

abstract：:Zika virus (ZIKV) nonstructural protein 5 (NS5) is a multifunctional protein possessing methyltransferase and RNA-dependent RNA polymerase activities. In the present study, we have carried out an extensive mutagenesis analysis to determine the importance of nuclear localization sequences (NLS) of NS5 in its nuclear ac...

journal_title：Virology

authors： Ji W,Luo G

更新日期：2020-02-01 00:00:00

abstract：:Nucleotide sequence determination of the coat protein cistron of the alfalfa mosaic virus (AIMV) temperature-sensitive mutant, Tbts 7 (uv) revealed a small number of point mutations of which only one results in the replacement of an amino acid: the asparagine residue at position 126 is replaced by an aspartate residue...

journal_title：Virology

authors： Huisman MJ,Cornelissen BJ,Groenendijk CF,Bol JF,van Vloten-Doting L

更新日期：1989-08-01 00:00:00

abstract：:Like human adenovirus type 5 (HAV5), bovine adenovirus type 3 (BAV3) early region 1 (E1) consists of E1A and E1B transcriptional units. In order to characterize BAV3 E1 proteins and to isolate a cell line of bovine origin that expresses BAV3 E1, polyclonal antibodies specific to E1A, E1B-157R, and E1B-420R were raised...

journal_title：Virology

authors： van Olphen AL,Tikoo SK,Mittal SK

更新日期：2002-03-30 00:00:00

abstract：:The phosphoprotein (P) of bovine respiratory syncytial virus (BRSV) is a multifunctional protein that plays a central role in transcription and replication of the viral genomic RNA. To investigate the domains and specific residues involved in different activities of the P protein, we generated a total of 22 deletion a...

journal_title：Virology

authors： Khattar SK,Yunus AS,Collins PL,Samal SK

更新日期：2001-07-05 00:00:00

abstract：:A clinical feature of Ross River virus disease (RRVD) is the periodic relapse of symptoms months after the initial onset of disease. The underlying mechanisms responsible for this relapse have not been determined. In a long-term (148 days) in vitro study of persistently infected murine macrophages we established that ...

journal_title：Virology

authors： Way SJ,Lidbury BA,Banyer JL

更新日期：2002-09-30 00:00:00

abstract：:Although H5N1 influenza viruses have been responsible for hundreds of human infections, these avian influenza viruses have not fully adapted to the human host. The lack of sustained transmission in humans may be due, in part, to their avian-like receptor preference. Here, we have introduced receptor binding domain mut...

journal_title：Virology

authors： Maines TR,Chen LM,Van Hoeven N,Tumpey TM,Blixt O,Belser JA,Gustin KM,Pearce MB,Pappas C,Stevens J,Cox NJ,Paulson JC,Raman R,Sasisekharan R,Katz JM,Donis RO

更新日期：2011-04-25 00:00:00

abstract：:The close association between human papillomavirus type 16 and cervical cancer implies some role for the virus in the development of this cancer. It has been demonstrated that HPV-16 DNA sequences in the presence of activated ras are capable of transforming primary baby rat kidney cells. This communication describes t...

journal_title：Virology

authors： Banks L,Crawford L

更新日期：1988-07-01 00:00:00

abstract：:The emergence and re-emergence of Zika virus (ZIKV), is a cause for international concern. These highly pathogenic arboviruses represent a serious health burden in tropical and subtropical areas worldwide. Despite these burdens, antiviral therapies do not exist, and inhibitors of ZIKV are therefore urgently needed. To...

journal_title：Virology

authors： Chen H,Lao Z,Xu J,Li Z,Long H,Li D,Lin L,Liu X,Yu L,Liu W,Li G,Wu J

更新日期：2020-07-01 00:00:00

abstract：:Superinfection exclusion (SIE), a phenomenon in which a preexisting viral infection prevents a secondary infection with the same or closely related virus, has been described for different viruses, including important pathogens of humans, animals, and plants. Several mechanisms acting at various stages of the viral lif...

journal_title：Virology

authors： Folimonova SY,Harper SJ,Leonard MT,Triplett EW,Shilts T

更新日期：2014-11-01 00:00:00

abstract：:Human nectin-1 (HveC, Prr1), a member of the immunoglobulin superfamily and a receptor for the entry of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), pseudorabies virus (PRV), and bovine herpesvirus 1 (BHV-1), binds to viral gD. For HSV-1, HSV-2, and PRV, the gD-binding region of nectin-1 has been localized to the N-...

journal_title：Virology

authors： Geraghty RJ,Fridberg A,Krummenacher C,Cohen GH,Eisenberg RJ,Spear PG

更新日期：2001-07-05 00:00:00

abstract：:Human parainfluenza virus type 1 (hPIV1) and type 3 (hPIV3) initiate infection by sialic acid binding. Here, we investigated sialic acid linkage specificities for binding and infection of hPIV1 and hPIV3 by using sialic acid linkage-modified cells treated with sialidases or sialyltransferases. The hPIV1 is bound to on...

journal_title：Virology

authors： Fukushima K,Takahashi T,Ito S,Takaguchi M,Takano M,Kurebayashi Y,Oishi K,Minami A,Kato T,Park EY,Nishimura H,Takimoto T,Suzuki T

更新日期：2014-09-01 00:00:00

abstract：:Viruses of the family Luteoviridae are ssRNA plant viruses that have particles that exhibit icosahedral symmetry. To identify the residues that might be exposed on the surface of the Potato leafroll virus (PLRV; genus Polerovirus, family Luteoviridae) capsid, and therefore involved in biological interactions, we perfo...

journal_title：Virology

authors： Terradot L,Souchet M,Tran V,Giblot Ducray-Bourdin D

更新日期：2001-07-20 00:00:00

abstract：:The HPV16 E7 oncoprotein and 17β-estradiol are important factors for the induction of premalignant lesions and cervical cancer. The study of these factors is crucial for a better understanding of cervical tumorigenesis. Here, we assessed the global gene expression profiles induced by the HPV16 E7 oncoprotein and/or 17...

journal_title：Virology

authors： Cortés-Malagón EM,Bonilla-Delgado J,Díaz-Chávez J,Hidalgo-Miranda A,Romero-Cordoba S,Uren A,Celik H,McCormick M,Munguía-Moreno JA,Ibarra-Sierra E,Escobar-Herrera J,Lambert PF,Mendoza-Villanueva D,Bermudez-Cruz RM,Gariglio P

更新日期：2013-12-01 00:00:00

abstract：:Unlike cell lines transformed with Polyomaviruses, transformants derived by focus formation or colony formation in agarose medium after transfer into rat fibroblast cells (FR3T3 line) of Bovine Papilloma Type 1 (BPV1) DNA were consistently observed to grow poorly in suspension and to remain highly serum dependent for ...

journal_title：Virology

authors： Grisoni M,Meneguzzi G,de Lapeyrière O,Binétruy B,Rassoulzadegan M,Cuzin F

更新日期：1984-06-01 00:00:00

abstract：:The complete nucleotide sequence of the nucleocapsid (N) gene of lettuce necrotic yellows virus (LNYV), the type member of the genus Cytorhabdovirus of plant rhabdoviruses, has been determined from cDNA clones of both the viral genomic and messenger RNAs. The previously identified N gene was adjacent to the 3' leader ...

journal_title：Virology

authors： Wetzel T,Dietzgen RG,Geering AD,Dale JL

更新日期：1994-08-01 00:00:00

abstract：:Hepatitis C virus (HCV) causes chronic hepatitis, which often results in the development of liver cirrhosis and hepatocellular carcinoma (HCC) worldwide. In this study, we demonstrated that the non-structural protein NS3 of HCV enhances cyclooxygenase-2 (COX-2) gene promoter activity, COX-2 mRNA expression, COX-2 prot...

journal_title：Virology

authors： Lu L,Wei L,Peng G,Mu Y,Wu K,Kang L,Yan X,Zhu Y,Wu J

更新日期：2008-02-05 00:00:00

abstract：:A human B-lymphoid cell line, designated TG8, which does not express detectable levels of the EBV (Epstein-Barr virus)-associated nuclear antigen (EBNA), yet carries an average of one to two plasmid copies of the P3HR-1 EBV genome has been identified. TG8 can be superinfected by B95-8 EBV, resulting in up to 60-70% of...

journal_title：Virology

authors： Reisman D,Sugden B

更新日期：1984-08-01 00:00:00

abstract：:Envelope viruses maturate by macromolecule assembly and budding. To investigate these steps, we generated virus-like particles (VLPs) by co-expression of structural proteins of Sendai virus (SeV), a prototype of the family Paramyxoviridae. Simultaneous expression of matrix (M), nucleo- (N), fusion (F), and hemagglutin...

journal_title：Virology

authors： Sugahara F,Uchiyama T,Watanabe H,Shimazu Y,Kuwayama M,Fujii Y,Kiyotani K,Adachi A,Kohno N,Yoshida T,Sakaguchi T

更新日期：2004-07-20 00:00:00

abstract：:We have studied the assembly of human immunodeficiency virus (HIV-1) Gag-B-galactosidase (Gag-B-gal; GBG) fusion proteins into HIV particles in the presence of HIV Gag proteins. Release of fusion proteins from cells was measured by assay of media versus cellular B-gal activities and was dependent on co-expression of u...

journal_title：Virology

authors： Wang CT,Stegeman-Olsen J,Zhang Y,Barklis E

更新日期：1994-05-01 00:00:00

abstract：:Urine and breast milk represent the main routes of human cytomegalovirus (HCMV) transmission but the contribution of renal and mammary epithelial cells to viral excretion remains unclear. We observed that kidney and mammary epithelial cells were permissive to HCMV infection and expressed immediate early, early and lat...

journal_title：Virology

authors： Twite N,Andrei G,Kummert C,Donner C,Perez-Morga D,De Vos R,Snoeck R,Marchant A

更新日期：2014-07-01 00:00:00

abstract：:The genetic diversity of group M HIV-1 is highest in west central Africa. Blood samples from four locations in Cameroon were collected to determine the molecular epidemiology of HIV-1. The C2-V5 region of envelope was sequenced from 39 of the 40 samples collected, and 7 samples were sequenced across the genome. All st...

journal_title：Virology

authors： Carr JK,Torimiro JN,Wolfe ND,Eitel MN,Kim B,Sanders-Buell E,Jagodzinski LL,Gotte D,Burke DS,Birx DL,McCutchan FE

更新日期：2001-07-20 00:00:00

abstract：:It was previously reported that integrins alpha2beta1, alpha4beta1, and alphaXbeta2 are involved in rotavirus cell infection. In this work we studied the role of integrin subunits alpha2, alpha4, and beta2 on the attachment of rotaviruses RRV and nar3 to MA104 cells. Integrin alpha2beta1 was found to serve as the bind...

journal_title：Virology

authors： Zárate S,Espinosa R,Romero P,Guerrero CA,Arias CF,López S

更新日期：2000-12-05 00:00:00

abstract：:Prior studies with recombinant viruses constructed in vitro showed that the V2 domain of envelope gp120, in addition to the required V3 domain, enhances the efficiency of infection of primary macrophages by HIV-1. Present structural studies on the gp120s of these recombinant viruses using three human monoclonal antibo...

journal_title：Virology

authors： Koito A,Stamatatos L,Cheng-Mayer C

更新日期：1995-02-01 00:00:00

abstract：:The mechanism of vaccinia virus-induced selective inhibition of host cell protein synthesis was studied in a nonpermissive (Chinese hamster ovary, CHO) and in a permissive mouse cell line ( L cells). Small polyadenylated RNAs obtained from uninfected and infected cells were fractionated into six size classes by polyac...

journal_title：Virology

authors： Su MJ,Bablanian R

更新日期：1990-12-01 00:00:00

abstract：:Previously, VLPs bearing JR-FL strain HIV-1 Envelope trimers elicited potent neutralizing antibodies (nAbs) in 2/8 rabbits (PLoS Pathog 11(5): e1004932) by taking advantage of a naturally absent glycan at position 197 that borders the CD4 binding site (CD4bs). In new immunizations, we attempted to improve nAb response...

journal_title：Virology

authors： Crooks ET,Osawa K,Tong T,Grimley SL,Dai YD,Whalen RG,Kulp DW,Menis S,Schief WR,Binley JM

更新日期：2017-05-01 00:00:00

abstract：:We have shown that the binding of simian immunodeficiency virus (SIV) to Jurkat T cells expressing CD4 receptor strongly induces mitogen-activated protein (MAP) kinase kinase (MEK) and extracellular signal-regulated kinases 1 and 2 (ERK1/2) and only weakly induces p38 MAP kinase and c-Jun N-terminal kinase (JNK). Simi...

journal_title：Virology

authors： Popik W,Pitha PM

更新日期：1998-12-05 00:00:00

abstract：:In this study, we show how the red spotted grouper nervous necrosis virus (RGNNV) causes loss of mitochondrial membrane potential and promotes host secondary apoptotic necrosis. RGNNV viral proteins such as protein alpha (42 kDa) and protein A (110 kDa) were quickly expressed between 12 h and 24 h postinfection (p.i.)...

journal_title：Virology

authors： Chen SP,Yang HL,Her GM,Lin HY,Jeng MF,Wu JL,Hong JR

更新日期：2006-04-10 00:00:00

abstract：:An in-frame gag gene mutant of human immunodeficiency virus type 1, which carries two amino acid substitutions in the center of the p24 coding region, was constructed in vitro, and its replication properties in several cell lines were examined. In CD4-negative SW480 cells transfected with the mutant clone, synthesis a...

journal_title：Virology

authors： Sakuragi J,Sakai H,Kawamura M,Tokunaga K,Ueda S,Adachi A

更新日期：1995-09-10 00:00:00