Abstract:
:Met-enkephalin, administered microiontophoretically, produced a greater increase in firing in cells in area CA 3-4 in the hippocampus of both young and aged Fisher 344 rats than it did in the CA 1 area. Furthermore, the effect of met-enkephalin on neuronal firing rates was not as great in old rats as it was in young rats. Finally, 20-40 nA of met-enkephalin produced an increase in firing in old rats that was equivalent to the difference (2.5 spikes/sec) in baseline firing between old (2.6 spikes/sec) and young rats (5.1 spikes/sec).
journal_name
Life Scijournal_title
Life sciencesauthors
Haigler HJ,Cahill LF,Crager MR,Charles Edoi
10.1016/0024-3205(87)90360-2subject
Has Abstractpub_date
1987-01-12 00:00:00pages
203-13issue
2eissn
0024-3205issn
1879-0631pii
0024-3205(87)90360-2journal_volume
40pub_type
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