Developmentally different onset of alpha 1- and alpha 2-adrenergic responses in the neonatal rat dorsal motor nucleus of the vagus in vitro.

abstract：:Porcine calcitonin (pCT) encapsulated in sulfatide-containing reverse-phase evaporation vesicles (REVs) was shown to induce long-lasting and dose-dependent antinociceptive effect by systemic injection in mice. Its antinociceptive activity is found to be dependent on the route of administration. In contrast, neither un...

journal_title：Brain research

authors： Chen D,Li QT,Lee KH

更新日期：1993-02-12 00:00:00

abstract：:Experiments were conducted to (1) provide further evidence of the selectivity of [D-Ala2,Leu5,Cys6]enkephalin (DALCE) as an antagonist of delta (delta) receptor ligands and (2) use DALCE as a tool to explore the possible role of delta receptors in restraint stress. Dose- and time-response curves were generated for the...

journal_title：Brain research

authors： Calcagnetti DJ,Bowen WD,Holtzman SG

更新日期：1990-02-19 00:00:00

abstract：:Electrical synaptic transmission via gap junctions has become an accepted feature of neuronal communication in the mammalian brain, and occurs often between dendrites of interneurons in major brain structures, including the hippocampus. Electrical and dye-coupling has also been reported to occur between pyramidal cell...

journal_title：Brain research

authors： Nagy JI

更新日期：2012-12-03 00:00:00

abstract：:It is known that the execution of the motor response in a simple reaction time (RT) task can be delayed by transcranial magnetic stimulation (TMS). This paper is aimed at determining the site of action where the delay in RT occurs. A delay in RT was obtained only at those TMS sites over the motor cortex contralateral ...

journal_title：Brain research

authors： Ziemann U,Tergau F,Netz J,Hömberg V

更新日期：1997-01-02 00:00:00

abstract：:We assessed the effects of simulated weightlessness, hindlimb unloading (HU) by 7 days of tail suspension, on noxious mechanically and heat evoked spinal withdrawal reflexes and spinal Fos expression during muscle nociception elicited by intramuscular (i.m.) injection of hypertonic (HT; 5.8%) saline into gastrocnemius...

journal_title：Brain research

authors： Lei J,Pertovaara A,You HJ

更新日期：2015-01-12 00:00:00

abstract：:It has been suggested that individual predisposition to develop amphetamine self-administration is associated with impairment in corticosteroid negative feedback mechanisms. Since corticosteroid receptors, particularly those in the hippocampus, are involved in corticosterone feedback sensitivity, we examined the relat...

journal_title：Brain research

authors： Maccari S,Piazza PV,Deminière JM,Angelucci L,Simon H,Le Moal M

更新日期：1991-05-10 00:00:00

abstract：:To understand the functional organization of the piriform cortex (PC), the axon collaterals of three pyramidal cells in layer IIb of the anterior PC and one pyramidal cell in layer IIb of the posterior PC were labeled and quantitatively analyzed by intracellular biocytin injection in the guinea pig. Single pyramidal c...

journal_title：Brain research

authors： ul Quraish A,Yang J,Murakami K,Oda S,Takayanagi M,Kimura A,Kakuta S,Kishi K

更新日期：2004-11-05 00:00:00

abstract：:Recent studies, which have shown an increase of plasma vasopressin (VP) in experimental motion sickness and the efficacy of VP antagonists for motion sickness, suggest an important role of VP in the development of vestibulo-autonomic responses. We have recently found evidence of the co-existence of vasopressinergic ne...

journal_title：Brain research

authors： Horii A,Koike K,Uno A,Uno Y,Kubo T

更新日期：2001-09-28 00:00:00

abstract：:Amyloid β-protein (Aβ) is the major component of extracellular plaques in the brains of patients with Alzheimer's disease. It has been suggested that the interaction of Aβ with membrane cholesterol is essential for Aβ to exert neurotoxicity; however, the effect of phospholipids, another major membrane lipid component,...

journal_title：Brain research

authors： Ko M,Hattori T,Abdullah M,Gong JS,Yamane T,Michikawa M

更新日期：2016-07-01 00:00:00

abstract：:Infusion of 15 micrograms/microliters (approximately 120 micrograms/kg/h) of indomethacin within the ventral septal area of the rat brain significantly reduced a centrally induced prostaglandin E1 (PGE1) hyperthermia when compared with infusions of artificial cerebrospinal fluid. A bolus injection of a V1 receptor ant...

journal_title：Brain research

authors： Fyda DM,Cooper KE,Veale WL

更新日期：1989-08-14 00:00:00

abstract：:The anesthetic-sedative barbiturate pentobarbital (PB) and the anticonvulsant barbiturate phenobarbital (PhB) were applied to mammalian spinal cord neurons in primary dissociated cell culture to assess their effects on: (1) postsynaptic GABA-responses; (2) paroxysmal activity produced by the convulsant bicuculline; (3...

journal_title：Brain research

authors： Schulz DW,Macdonald RL

更新日期：1981-03-23 00:00:00

abstract：:The location of stapedius motoneurons in the rat was determined with horseradish peroxidase (HRP) retrograde tracing techniques. After injection of free HRP or wheat germ agglutinin-horseradish peroxidase (WGA-HRP) in the stapedius muscle on one side, labeled neurons were seen ipsilaterally in a region ventromedial to...

journal_title：Brain research

authors： Rouiller EM,Capt M,Dolivo M,De Ribaupierre F

更新日期：1989-01-02 00:00:00

abstract：:The D stereoisomer of dihydroxyphenylalanine (D-DOPA) and its alpha-keto acid metabolite 3,4-dihydroxyphenylpyruvic acid (DHPPA) when infused into the striatum, significantly increased in vivo extracellular dopamine levels. Following D-DOPA administration, the cumulative increase in dopamine levels was 30% of the incr...

journal_title：Brain research

authors： Brannan T,Prikhojan A,Yahr MD

更新日期：1996-04-29 00:00:00

abstract：:In the present study, temporal changes of voltage-gated Ca(2+) channel (VGCC) immunoreactivities were evaluated in the gerbil hippocampus following ischemia. P/Q-type VGCC immunoreactivity was elevated in the hippocampus in the 3 h post-ischemic group. In the 30 min post-ischemic group, N-type VGCC immunoreactivity be...

journal_title：Brain research

authors： Park SK,An SJ,Hwang IK,Suh JG,Oh YS,Won MH,Kang TC

更新日期：2003-04-25 00:00:00

abstract：:This study was performed to understand the anatomical substrates of hypothalamic modulation of jaw movements. After cholera toxin B subunit (CTb) injection into the parvicellular reticular formation (RFp) of the rat medulla oblongata, where many trigeminal premotor neurons have been known to exist, numerous CTb-labele...

journal_title：Brain research

authors： Notsu K,Tsumori T,Yokota S,Sekine J,Yasui Y

更新日期：2008-12-09 00:00:00

abstract：:To determine whether the cytokine, interleukin-1 beta, is present in the rat brain as has been reported in human brain, immunocytochemical studies were performed using an antiserum that recognizes recombinant, rat IL-1 beta. Immunoreaction product was present in the periventricular and medial hypothalamus, mossy fiber...

journal_title：Brain research

authors： Lechan RM,Toni R,Clark BD,Cannon JG,Shaw AR,Dinarello CA,Reichlin S

更新日期：1990-04-23 00:00:00

abstract：:Experiments were carried out in rats to (1) elaborate upon the sepcificity of drug action in the periaqueductal gray matter (PAG), and (2) to evaluate the posible congruence of PAG sites of morphine-induced and stimulation-produced analgesis (SPA) applied at virtually identical PAG loci. It was demonstrated that the e...

journal_title：Brain research

authors： Lewis VA,Gebhart GF

更新日期：1977-03-25 00:00:00

abstract：:The distribution of immunoreactive (IR) axons and neurons in the rat central nervous system (CNS) has been studied with an antiserum directed against the C-terminal sequence of rat a-calcitonin gene-related peptide (CGRP) and a durable peroxidase reaction product for detailed analysis in relation to normal cytoarchite...

journal_title：Brain research

authors： Kruger L,Mantyh PW,Sternini C,Brecha NC,Mantyh CR

更新日期：1988-11-01 00:00:00

abstract：:Placental Opioid-Enhancing Factor (POEF) is a substance found in amniotic fluid (AF) that, when ingested, potentiates opioid-mediated, but not non-opioid-mediated, hypoalgesia. Vaginal-cervical stimulation (VCS) produces a stimulus-bound, partially opioid-mediated hypoalgesia that previous research has shown to be pot...

journal_title：Brain research

authors： Hoey RF,Hurley SW,Daniels D,Kristal MB

更新日期：2011-02-28 00:00:00

abstract：:The effects of dopamine on glutamate-induced cytotoxicity were examined using the primary cultures of rat striatal neurons. Cell viability was significantly reduced by exposure of cultures to glutamate or kainate for 24 h. In contrast, similar application of N-methyl-D-aspartate (NMDA) or alpha-amino-3-hydroxy-5-methy...

journal_title：Brain research

authors： Amano T,Ujihara H,Matsubayashi H,Sasa M,Yokota T,Tamura Y,Akaike A

更新日期：1994-08-29 00:00:00

abstract：:Gastrin-releasing peptide (GRP) mediated signals in the central nervous system (CNS) influence many functions associated with energy metabolism. The purpose of the present study was to investigate the central effect of GRP on glucose metabolism in the male rat. Intracerebroventricular (icv) administration of GRP cause...

journal_title：Brain research

authors： Jha PK,Foppen E,Challet E,Kalsbeek A

更新日期：2015-11-02 00:00:00

abstract：:Embryonic cortex from 19-day fetuses was transplanted in a medial frontal cortex wound cavity of 105-day-old male rats. Nissl-stained tissue revealed little internal laminar organization. Graft sections impregnated by the Loyez method exhibited bands of myelinated fibers surrounding implants as well as long-interconne...

journal_title：Brain research

authors： Mufson EJ,Labbe R,Stein DG

更新日期：1987-01-13 00:00:00

abstract：:3,4-Dihydroxyphenylglycolaldehyde (DOPEGAL) is the monoamine oxidase A metabolite of norepinephrine and epinephrine. DOPEGAL, but not other metabolites, kills differentiated PC-12 cells. However, the type of DOPEGAL induced cell death, whether necrosis or apoptosis, is not known. To determine the type of cell death tr...

journal_title：Brain research

authors： Burke WJ,Schmitt CA,Miller C,Li SW

更新日期：1997-06-20 00:00:00

abstract：:The present study investigated the effect of dextromethorphan and 6,7-dinitroquinoxaline-2,3-dione (DNQX) pre-treatment on the development of cocaine- and lidocaine-induced seizures. The dopaminergic action of cocaine was also studied. The NMDA antagonist dextromethorphan and the non-NMDA (AMPA/kainate) antagonist DNQ...

journal_title：Brain research

authors： Barat SA,Abdel-Rahman MS

更新日期：1997-05-09 00:00:00

abstract：:Central catecholaminergic nerves have been shown to participate in the integration of cardio-cardiac reflexes induced by coronary artery ligation in the rat. In this study we measured the turnover of dopamine, norepinephrine and epinephrine in microdissected brain regions to identify some of the specific neural loci i...

journal_title：Brain research

authors： Sole MJ,Hussain MN,Versteeg DH,de Kloet ER,Adams D,Lixfeld W

更新日期：1982-03-11 00:00:00

abstract：:We examined the effects of chronic social stress and social rank on monamine concentrations in the prefrontal cortex (PFC) in adult male cynomolgus macaques (Macaca fascicularis). Seventy-five animals were housed in five-member social groups for 28 months and were exposed to three experimental conditions. A 'no-stress...

journal_title：Brain research

authors： Fontenot MB,Kaplan JR,Manuck SB,Arango V,Mann JJ

更新日期：1995-12-24 00:00:00

abstract：:Environmental stressors can substantially affect the adaptive response of rats to novelty in a sexually dimorphic manner. Gender-related differences are also observed in neurochemical and behavioural patterns of adult rats following prenatal exposure to diazepam (DZ). In the present study the behavioural reactivity to...

journal_title：Brain research

authors： Cannizzaro C,Martire M,Cannizzaro E,Provenzano G,Gagliano M,Carollo A,Mineo A,Steardo L

更新日期：2001-06-22 00:00:00

abstract：:Transependymal absorption of cerebrospinal fluid (CSF) in hydrocephalus is suggested by periventricular edema, but the necessary bulk flow of interstitial fluid (ISF) has not been found. We performed ventriculocisternal perfusions in adult cats using CSF with the extracellular marker [3H]sucrose. CSF pressure was main...

journal_title：Brain research

authors： Rosenberg GA,Kyner WT,Estrada E

更新日期：1982-01-28 00:00:00

abstract：:Detailed quantitative information on catecholamines and 5-hydroxytryptamine (serotonin) in the human thalamus is much needed because of increasing interest in norepinephrine and serotonin as modulators of thalamic behavioral state control and overall information processing. This study provides three-dimensional distri...

journal_title：Brain research

authors： Oke AF,Carver LA,Gouvion CM,Adams RN

更新日期：1997-07-18 00:00:00

abstract：:The effect of intracerebroventricular (i.c.v.) infusion of various iso- and hypertonic saccharide solutions on water intake stimulated by intracarotid (i.c.) infusion of hypertonic NaCl was studied in sheep. Without an i.c.v. infusion, water intake during a 10-min period following an i.c. infusion of 4 M NaCl (1.4 ml/...

journal_title：Brain research

authors： Park R,Denton DA,McKinley MJ,Pennington G,Weisinger RS

更新日期：1989-07-24 00:00:00