Abstract:
:Peripheral blood T-cell subsets of 70 patients with untreated gastric cancer and 55 age- and sex-matched normal controls were studied by using monoclonal antibodies and flow cytometry. The number of T cells (Leu 4+ cells) was significantly decreased in stage IV patients. Statistically significant decreases in the number of Leu 3a+ cells and in the Leu 3a+/Leu 2a+ ratio were also found in stage IV patients. Stage I-III patients showed no marked imbalance in T-cell subsets. Quantitative changes in T-cell subsets in the advanced stage may be one of the factors responsible for the immunosuppression in advanced gastric cancer.
journal_name
Oncologyjournal_title
Oncologyauthors
Watanabe T,Nakauchi H,Kitaoka H,Matsuki K,Okumura K,Nomura K,Takakura Kdoi
10.1159/000226007subject
Has Abstractpub_date
1985-01-01 00:00:00pages
89-91issue
2eissn
0030-2414issn
1423-0232journal_volume
42pub_type
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