Abstract:
:In this issue of Blood, the findings of Chakraborty et al and Emile et al support a model in which the mitogen-activated protein kinase (MAPK) and PI3K/AKT pathways are critical in the pathogenesis of 2 of the most common histiocytoses—Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD)—whereas their respective mutational profiles demonstrate important similarities and differences.
journal_name
Bloodjournal_title
Bloodauthors
Prince HMdoi
10.1182/blood-2014-09-597765subject
Has Abstractpub_date
2014-11-06 00:00:00pages
2901-3issue
19eissn
0006-4971issn
1528-0020pii
124/19/2901journal_volume
124pub_type
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