First study of intra-arterial delivery of myogenic mononuclear cells to skeletal muscles in primates.

abstract：:We examined whether hypoxic exposure prior to the event of transplantation would have a positive or negative effect upon later islet graft function. Mouse islets exposed to hypoxic culture were transplanted into syngeneic recipients. Islet graft function, β-cell physiology, as well as molecular changes were examined. ...

journal_title：Cell transplantation

authors： Cantley J,Walters SN,Jung MH,Weinberg A,Cowley MJ,Whitworth TP,Kaplan W,Hawthorne WJ,O'Connell PJ,Weir G,Grey ST

更新日期：2013-01-01 00:00:00

abstract：:Cell therapy has been shown to be a promising alternative therapy for neurorestoration, and more than 30 different types of cells have been shown to possess some capability to restore lost or damaged neurological functions. Chinese physicians have successfully applied cell therapy to many neurological diseases and dam...

journal_title：Cell transplantation

authors： Chinese Branch of International Association of Neurorestoratology (IANR).,Preparatory Committee of Chinese Association of Neurorestoratology.

更新日期：2013-01-01 00:00:00

abstract：:Wharton's jelly-derived mesenchymal stromal cells (WJ-MSCs) have distinct immunomodulatory and protective effects against kidney, liver, or heart injury. Limited studies have shown that WJ-MSCs attenuates oxygen-glucose deprivation-mediated inflammation in hippocampal slices. The neuroprotective effect of intracerebra...

journal_title：Cell transplantation

authors： Wu KJ,Yu SJ,Chiang CW,Lee YW,Yen BL,Tseng PC,Hsu CS,Kuo LW,Wang Y

更新日期：2018-11-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is a malignant tumor of the upper aerodigestive tract affecting the oral cavity, lips, paranasal sinuses, larynx, and nasopharynx. Proteogenomics combines proteomics and genomics and employs mass spectrometry and high-throughput sequencing technologies to identify novel pe...

journal_title：Cell transplantation

authors： Wu ZH,Yun-Tang,Cheng Q

更新日期：2020-01-01 00:00:00

abstract：:Acute myocardial infarction (AMI) results in ischemic damage and death of cardiomyocytes and loss of vasculature. Stem cell therapy has emerged as a potentially promising strategy for maximizing cardiac function following ischemic injury. Issues of cell source, delivery, and quantification of response have challenged...

journal_title：Cell transplantation

authors： Medicetty S,Wiktor D,Lehman N,Raber A,Popovic ZB,Deans R,Ting AE,Penn MS

更新日期：2012-01-01 00:00:00

abstract：:Circular RNAs (circRNAs) could sponge micro-RNAs (miRNAs) to regulate tumor progression of hepatocellular carcinoma (HCC). Hsa_circ_104566 contributes to papillary thyroid carcinoma progression. However, the tumorigenic mechanism of hsa_circ_104566 on HCC remains enigmatic. The role of hsa_circ_104566 on HCC was there...

journal_title：Cell transplantation

authors： Liu G,Guo W,Rao M,Qin J,Hu F,Li K

更新日期：2020-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) hold great promise for bone regeneration. However, the power of mesenchymal stem cells has not been applied to structural bone allografts in clinical practice. This study designed a new strategy to enhance the efficiency of allografts for segmental bone regeneration. Isolated MSCs were cu...

journal_title：Cell transplantation

authors： Zou XH,Cai HX,Yin Z,Chen X,Jiang YZ,Hu H,Ouyang HW

更新日期：2009-01-01 00:00:00

abstract：:The cytology of peritoneal washing fluids for gastric cancer is the most basic method for judging peritoneal micrometastasis. However, the clinical value of this method is not clear at present. A retrospective analysis was performed on 277 patients with pathologically proven and surgically treated gastric cancer. The ...

journal_title：Cell transplantation

authors： Jiang RP,Xiong XJ,Qiu XS,Wang EH,Wu GP

更新日期：2019-11-01 00:00:00

abstract：:Cerebral palsy (CP) is a common disability which results in permanent chronic motor disability appearing in early childhood. Recently human umbilical cord blood mesenchymal stem cell (hUCB-MSC) infusion has emerged as a promising therapeutic strategy for CP, and the treatment efficacy remains to be confirmed by clinic...

journal_title：Cell transplantation

authors： Huang L,Zhang C,Gu J,Wu W,Shen Z,Zhou X,Lu H

更新日期：2018-02-01 00:00:00

abstract：:Peripheral blood samples from HIV-seropositive individuals enrolled in a pilot clinical trial investigating the use of allogeneic dendritic cell therapy were evaluated for mixed chimerism. In this study, dendritic cells from HLA-identical, HIV-seronegative siblings were used. Patients received an infusion of dendritic...

journal_title：Cell transplantation

authors： Shapero MH,Kundu SK,Engleman E,Laus R,van Schooten WC,Merigan TC

更新日期：2000-05-01 00:00:00

abstract：:We have recently reported that small-sized bone marrow cells (BMCs) isolated by counterflow centrifugal elutriation and depleted of lineage markers (Fr25lin(-)) have the capacity to differentiate and contribute to regeneration of injured islets. In this study, we assess some of the characteristics of these cells compa...

journal_title：Cell transplantation

authors： Iskovich S,Goldenberg-Cohen N,Sadikov T,Yaniv I,Stein J,Askenasy N

更新日期：2015-01-01 00:00:00

abstract：:To investigate potential cures for spinal cord injury (SCI), several researchers have transplanted neural stem/progenitor cells (NS/PCs) into the injured spinal cord by different procedures, including intralesional (IL), intrathecal (IT), and intravenous (IV) injection. However, there are no reports quantifying or com...

journal_title：Cell transplantation

authors： Takahashi Y,Tsuji O,Kumagai G,Hara CM,Okano HJ,Miyawaki A,Toyama Y,Okano H,Nakamura M

更新日期：2011-01-01 00:00:00

abstract：:We transplanted adult whole bone marrow prelabeled with bromodeoxyuridine (BrdU) into the ischemic boundary zone of the adult rat brain at 1 day after 2 h of middle cerebral artery occlusion (MCAo). Approximately 3.3% of 10(6) transplanted bone marrow cells were BrdU reactive at 14 days after MCAo. BrdU-reactive cells...

journal_title：Cell transplantation

authors： Li Y,Chen J,Chopp M

更新日期：2001-01-01 00:00:00

abstract：:This study aimed to identify the beneficial effects of adipose tissue-derived mesenchymal stem cells (ASCs) and ASCs that overexpress the CTLA4Ig gene (CTLA4Ig-ASCs) on established autoimmune thyroiditis and to examine changes in clinical chemistry parameters and the presence of humoral responses upon repeated long-te...

journal_title：Cell transplantation

authors： Choi EW,Lee JM,Lee HW,Yang J,Youn HY

更新日期：2015-01-01 00:00:00

abstract：:Islet isolation involves enzymatic digestion of the interstitial matrix and mechanical disruption of the tissue. It is possible that a fundamental change of islet biology resulting from the loss of critical factors required for islet function or survival will occur. Extracellular matrix (ECM) is one of the most import...

journal_title：Cell transplantation

authors： Nagata N,Gu Y,Hori H,Balamurugan AN,Touma M,Kawakami Y,Wang W,Baba TT,Satake A,Nozawa M,Tabata Y,Inoue K

更新日期：2001-01-01 00:00:00

abstract：:In this study the time course of homing and the body distribution of systemically delivered bone marrow mesenchymal stem cells (BM-MSCs) after myocardial infarction (MI) were evaluated. BM-MSCs were isolated from Wistar rats, expanded in vitro, and their phenotypical characterization was performed by flow cytometer. R...

journal_title：Cell transplantation

authors： Assis AC,Carvalho JL,Jacoby BA,Ferreira RL,Castanheira P,Diniz SO,Cardoso VN,Goes AM,Ferreira AJ

更新日期：2010-01-01 00:00:00

abstract：:Experiments are described using rats with two kinds of brain damage and consequent cognitive deficit (in the Morris water maze, three-door runway, and radial maze): 1) ischemic damage to the CA1 hippocampal cell field after four-vessel occlusion (4VO), and 2) damage to the forebrain cholinergic projection system by lo...

journal_title：Cell transplantation

authors： Gray JA,Grigoryan G,Virley D,Patel S,Sinden JD,Hodges H

更新日期：2000-03-01 00:00:00

abstract：:Epithelial wound repair assures the recovery of the epithelial barrier after wounding. During wound healing epithelial cells migrate to cover the wound surface. The presented experiments were carried out to compare the migration of human keratinocytes from primary and secondary culture on polystyrene, collagen, and fi...

journal_title：Cell transplantation

authors： Drukała J,Bandura L,Cieślik K,Korohoda W

更新日期：2001-01-01 00:00:00

abstract：:In human neonates, immature GABAergic interneurons are markedly affected by an excitotoxic insult. While in adults the interest of cell transplantation has been demonstrated in several neurological disorders, few data are available regarding the immature brain. The low survival rate constitutes a strong limitation in ...

journal_title：Cell transplantation

authors： Roux C,Lesueur C,Aligny C,Brasse-Lagnel C,Genty D,Marret S,Laquerrière A,Bekri S,Gonzalez BJ

更新日期：2014-01-01 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is an inherited disease and a main target of myogenic cell transplantation (MT). After the failure of the first clinical trials with DMD patients, the poor migration of transplanted cells has been suspected to be a major problem for a more effective clinical application of MT. Previou...

journal_title：Cell transplantation

authors： Lafreniere JF,Caron MC,Skuk D,Goulet M,Cheikh AR,Tremblay JP

更新日期：2009-01-01 00:00:00

abstract：:The development of new cell replacement strategies using neural stem cells (NSC) may provide an alternative and unlimited cell source for clinical neural transplantation in neurodegenerative diseases such as Parkinson's and Huntington's disease. The clinical application of neural transplantation using NSC will therefo...

journal_title：Cell transplantation

authors： McLeod M,Hong M,Sen A,Sadi D,Ulalia R,Behie LA,Mendez I

更新日期：2006-01-01 00:00:00

abstract：:The human neuronal cell-1 (HCN-1) line has recently been established. Under favorable conditions, these cells differentiate into mature neuronal phenotypes. Here we report on further characterization of these cells. Cultured HCN-1 cells express fibronectin immunoreactivity and grow well on fibronectin substrate but do...

journal_title：Cell transplantation

authors： Poltorak M,Isono M,Freed WJ,Ronnett GV,Snyder SH

更新日期：1992-01-01 00:00:00

abstract：:Cell and tissue culture techniques have improved considerably since the first attempts to maintain explants of animal tissue in vitro. The two major developments that have allowed these improvements are the ability to produce continuous cell lines, thus allowing reproducible results to be obtained, and the definition ...

journal_title：Cell transplantation

authors： Clayton HA,London NJ

更新日期：1996-01-01 00:00:00

abstract：:To learn more about nonimmune-mediated islet graft failure, we transplanted different preparations (preps) of isolated human islets under the kidney capsule of streptozotocin (STZ)-diabetic nude mice. One month after the implantation of 1,000 or 2,000 islets, grafts were harvested for morphological, immunohistochemica...

journal_title：Cell transplantation

authors： Davalli AM,Perego L,Bertuzzi F,Finzi G,La Rosa S,Blau A,Placidi C,Nano R,Gregorini L,Perego C,Capella C,Folli F

更新日期：2008-01-01 00:00:00

abstract：:Grafting autologous cultured satellite cells in irreversibly injured rat extensor digitorum longus EDL muscle leads to myofiber regeneration at the grafting site. In this study, we investigated whether cell grafts induced functional improvement and correlated mechanophysiological findings with histological observation...

journal_title：Cell transplantation

authors： Alameddine HS,Louboutin JP,Dehaupas M,Sébille A,Fardeau M

更新日期：1994-01-01 00:00:00

abstract：:As a putative marker of cerebral small vessel disease, cerebral microbleeds (CMBs) have been associated with vascular cognitive impairment. Both iron accumulation and amyloid protein precursor (APP) dysregulation are recognized as pathological hallmarks underlying the progression of CMBs, but their cross-talk is not y...

journal_title：Cell transplantation

authors： Gong L,Tian X,Zhou J,Dong Q,Tan Y,Lu Y,Wu J,Zhao Y,Liu X

更新日期：2019-08-01 00:00:00

abstract：:Apoptosis is a vital pathological factor that accounts for the poor prognosis of traumatic spinal cord injury (t-SCI). The 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is a critical regulator for energy metabolism and proven to have antiapoptotic effects. This study aimed to investigate the neuroprote...

journal_title：Cell transplantation

authors： Gao L,Wang C,Qin B,Li T,Xu W,Lenahan C,Ying G,Li J,Zhao T,Zhu Y,Chen G

更新日期：2020-01-01 00:00:00

abstract：:It is currently said that CO has anti-inflammatory and antiapoptosis effects and it has attracted attention as a medical gas. We used CO for rat hearts and conducted a preservation experiment. We isolated rat hearts, placed them into a specially made chamber, filled the chamber with a gas mixture of PCO (4,000 hPa) a...

journal_title：Cell transplantation

authors： Hatayama N,Naito M,Hirai S,Yoshida Y,Kojima T,Seki K,Li XK,Itoh M

更新日期：2012-01-01 00:00:00

abstract：:Clinically, many candidates for islet transplantation are already immunized, which increases their risk of graft rejection. Encapsulation of pancreatic islets using the TheraCyte™ device has been shown to protect against allograft rejection in nonimmunized recipients. However, the capacity of the TheraCyte™ device to ...

journal_title：Cell transplantation

authors： Kumagai-Braesch M,Jacobson S,Mori H,Jia X,Takahashi T,Wernerson A,Flodström-Tullberg M,Tibell A

更新日期：2013-01-01 00:00:00

abstract：:The estimated frequency of MSCs in BM is about 0.001-0.01% of total nucleated cells. Most commonly, one applied therapeutic cell dose is about 1-5 million MSCs/kg body weight, necessitating a reliable, fast, and safe expansion system. The limited availability of MSCs demands for an extensive ex vivo amplification step...

journal_title：Cell transplantation

authors： Rojewski MT,Fekete N,Baila S,Nguyen K,Fürst D,Antwiler D,Dausend J,Kreja L,Ignatius A,Sensebé L,Schrezenmeier H

更新日期：2013-01-01 00:00:00