6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Suppresses Neuronal Apoptosis by Increasing Glycolysis and "cyclin-dependent kinase 1-Mediated Phosphorylation of p27 After Traumatic Spinal Cord Injury in Rats.

abstract：:Gastric cancer (GC) is a leading cause of cancer-related death with poor prognosis. Growing evidence has shown that long noncoding ribonucleic acid (lncRNA) FEZ family zinc finger 1 antisense RNA 1(FEZF1-AS1), an "oncogene," regulates tumor progression and supports cancer stem cell. However, the tumorigenic mechanism ...

journal_title：Cell transplantation

authors： Hui Y,Yang Y,Li D,Wang J,Di M,Zhang S,Wang S

更新日期：2020-01-01 00:00:00

abstract：:Hypoxia is an adverse condition that can jeopardize the function of a bioartificial pancreatic construct. In this study we have investigated the effects of short-term hypoxic exposure (up to 24 h) on the bioenergetic status, metabolism, and insulin secretion of perfused pancreatic constructs composed of alginate/poly-...

journal_title：Cell transplantation

authors： Papas KK,Long RC Jr,Constantinidis I,Sambanis A

更新日期：2000-05-01 00:00:00

abstract：:Early graft loss in islet transplantation means that a large amount of donor islets is required. Endothelial cells and endothelial colony-forming cells (ECFCs) have been reported to improve instant blood-mediated inflammatory reaction (IBMIR) in vitro. In this study, we examined if ECFC-coated porcine islets would pre...

journal_title：Cell transplantation

authors： Jung HS,Kim MJ,Hong SH,Lee YJ,Kang S,Lee H,Chung SS,Park JS,Park KS

更新日期：2014-03-01 00:00:00

abstract：:Alzheimer's disease (AD) is a type of neurodegenerative disorder and the most common form of dementia. MicroRNA (miRNA) has been shown to play a role in various diseases, including AD. It also has been reported to regulate autophagy. We extracted miRNA from blood samples and constructed an miRNA-101a lentivirus vector...

journal_title：Cell transplantation

authors： Li Q,Wang Y,Peng W,Jia Y,Tang J,Li W,Zhang JH,Yang J

更新日期：2019-08-01 00:00:00

abstract：:Cardiovascular disease is a major cause of morbidity, disability, and mortality in kidney transplant patients. Cumulative reports indicate that the excessive risk of cardiovascular events is not entirely explained by the increased prevalence of traditional cardiovascular risk factors. Atherosclerosis is a chronic infl...

journal_title：Cell transplantation

authors： Ducloux D,Bamoulid J,Crepin T,Rebibou JM,Courivaud C,Saas P

更新日期：2017-09-01 00:00:00

abstract：:We investigated the effects of environmental enrichment (EE) on the function of transplanted adipose stem cells (ASCs) and the combined effect of EE and ASC transplantation on neurobehavioral function in an animal model of chronic hypoxic-ischemic (HI) brain injury. HI brain damage was induced in 7-day-old mice by uni...

journal_title：Cell transplantation

authors： Seo JH,Kim H,Park ES,Lee JE,Kim DW,Kim HO,Im SH,Yu JH,Kim JY,Lee MY,Kim CH,Cho SR

更新日期：2013-01-01 00:00:00

abstract：:Cell and tissue culture techniques have improved considerably since the first attempts to maintain explants of animal tissue in vitro. The two major developments that have allowed these improvements are the ability to produce continuous cell lines, thus allowing reproducible results to be obtained, and the definition ...

journal_title：Cell transplantation

authors： Clayton HA,London NJ

更新日期：1996-01-01 00:00:00

abstract：:In this study the time course of homing and the body distribution of systemically delivered bone marrow mesenchymal stem cells (BM-MSCs) after myocardial infarction (MI) were evaluated. BM-MSCs were isolated from Wistar rats, expanded in vitro, and their phenotypical characterization was performed by flow cytometer. R...

journal_title：Cell transplantation

authors： Assis AC,Carvalho JL,Jacoby BA,Ferreira RL,Castanheira P,Diniz SO,Cardoso VN,Goes AM,Ferreira AJ

更新日期：2010-01-01 00:00:00

abstract：:A human embryonic stem cell (HESC) line, H1, was studied after differentiation to a dopaminergic phenotype in vitro in order to carry out in vivo studies in Parkinsonian monkeys. To identify morphological characteristics of transplanted donor cells, HESCs were transfected with a GFP lentiviral vector. Gene expression ...

journal_title：Cell transplantation

authors： Wakeman DR,Weiss S,Sladek JR,Elsworth JD,Bauereis B,Leranth C,Hurley PJ,Roth RH,Redmond DE

更新日期：2014-01-01 00:00:00

abstract：:Despite the substantial efforts to elucidate the role of early brain injury in subarachnoid hemorrhage (SAH), an effective pharmaceutical therapy for patients with SAH continues to be unavailable. This study aims to reveal the role of necroptosis after SAH, and explore whether the disruption of the blood-brain barrier...

journal_title：Cell transplantation

authors： Chen J,Jin H,Xu H,Peng Y,Jie L,Xu D,Chen L,Li T,Fan L,He P,Ying G,Gu C,Wang C,Wang L,Chen G

更新日期：2019-11-01 00:00:00

abstract：:Pancreas procurement for islet isolation and transplantation is limited by concerns for the detrimental effects of postmortem ischemia. Hypothermic machine perfusion (HMP) preservation technology has had a major impact in circumventing ischemic injury in clinical kidney transplantation and is applied here to the prese...

journal_title：Cell transplantation

authors： Taylor MJ,Baicu S,Greene E,Vazquez A,Brassil J

更新日期：2010-01-01 00:00:00

abstract：:During the past 15 years, a variety of peptides, known as protein transduction domains (PTDs), or cell-penetrating peptides (CPPs), have been characterized for their ability to translocate into live cells. There are now numerous examples of biologically active full-length proteins and peptides that have been successfu...

journal_title：Cell transplantation

authors： Noguchi H,Matsushita M,Kobayashi N,Levy MF,Matsumoto S

更新日期：2010-01-01 00:00:00

abstract：:Stem cell-based therapy shows great potential in stroke patients. Intra-artery infusion exhibits greater biological distribution compared to intravenous delivery. In addition, umbilical cord mesenchymal stem cells (UCMSCs) have several advantages compared with other types of stem cells. The aim of this study was to ev...

journal_title：Cell transplantation

authors： Jiang Y,Zhu W,Zhu J,Wu L,Xu G,Liu X

更新日期：2013-01-01 00:00:00

abstract：:The technologies for adipose tissue harvesting, processing, and transplantation have substantially evolved in the past two decades. Clinically driven advancements have paralleled a significant improvement in the understanding of cellular, molecular, and immunobiological events surrounding cell and tissue transplantati...

journal_title：Cell transplantation

authors： Tremolada C,Palmieri G,Ricordi C

更新日期：2010-01-01 00:00:00

abstract：:Spinal cord injury (SCI) is a devastating neurological disease. The pathophysiological mechanisms of SCI have been reported to be relevant to central nervous system injury such as brain injury. In this study, gene expression of the brain after SCI was elucidated using transcriptome analysis to characterize the tempora...

journal_title：Cell transplantation

authors： Baek A,Cho SR,Kim SH

更新日期：2017-07-01 00:00:00

abstract：:Prior studies have suggested the possibility of immune-mediated death of xenogeneic hepatocytes in a bioartificial liver (BAL) during hemoperfusion. This study was designed to elucidate how immunity may cause death of xenogeneic hepatocytes in the BAL. Healthy dogs were treated with a BAL containing hollow fiber membr...

journal_title：Cell transplantation

authors： Nyberg SL,Amiot B,Hardin J,Baskin-Bey E,Platt JL

更新日期：2004-01-01 00:00:00

abstract：:Antibodies to the ligand for CD40 (CD154) have been shown to exert profound effects on the development of cell-mediated immune responses in mice. The present study shows that an antibody to human CD154 (hCD40L) inhibits in vivo Tetanus toxoid (TT) specific secondary antibody responses in hu-PBL-scid mice, as well as t...

journal_title：Cell transplantation

authors： Foy TM,McIlraith M,Masters SR,Dunn JJ,Rossini AA,Shultz LD,Hesselton RA,Wagar EJ,Lipsky PE,Noelle RJ,Greiner DL

更新日期：1998-01-01 00:00:00

abstract：:Pigs share many anatomical and physiological features with humans, offering a unique and viable model for biomedical research. Although porcine female germline stem cells (FGSCs) were identified in the juvenile ovary, no reports described the isolation and purification of FGSCs from the pig at sexual maturity. Here, w...

journal_title：Cell transplantation

authors： Hou L,Wang J,Li X,Wang H,Liu G,Xu B,Mei X,Hua X,Wu J

更新日期：2018-08-01 00:00:00

abstract：:Mononuclear stem cells have been studied for their potential in myocardial ischemia. In our previous published article, ReACT(®) phase I/II clinical trial, our results suggest that a certain cell population, promonocytes, directly correlated with the perceived angiogenesis in refractory angina patients. This study is ...

journal_title：Cell transplantation

authors： Hossne NA,Cruz E,Buffolo E,Coimbra AC,Machado J,Goldenberg RC,Regazzi G,Azevedo S,Invitti AL,Rodrigues Branco JN,Rodrigues de Oliveira JS,Stolf NA,Miller LW,Sanberg PR

更新日期：2015-01-01 00:00:00

abstract：:The diverse requirements for a successful islet encapsulation barrier suggest the benefit of a barrier system that presents differing functionalities to encapsulated cells and host cells. Initially, multifunctional hydrogels were synthesized via the sequential photopolymerization of PEG hydrogel layers, each with diff...

journal_title：Cell transplantation

authors： Weber LM,Cheung CY,Anseth KS

更新日期：2007-11-01 00:00:00

abstract：:Neuronal progenitor cells (NPCs) derived from human embryonic stem cells (hESCs) are an excellent cell source for transplantation therapy due to their availability and ethical acceptability. However, the traditional method of expansion and differentiation of hESCs into NPCs in monolayer cultures requires a long time, ...

journal_title：Cell transplantation

authors： Qiu L,Lim YM,Chen AK,Reuveny S,Oh SK,Tan EK,Zeng L

更新日期：2016-01-01 00:00:00

abstract：:Hepatocyte transplantation has been proposed as a technique for bridging patients to whole-organ transplantation, for providing metabolic support during liver failure, and for replacing whole-organ transplantation in certain metabolic liver diseases. Assessment of hepatocyte engraftment has been difficult to measure, ...

journal_title：Cell transplantation

authors： Mas VR,Maluf DG,Thompson M,Ferreira-Gonzalez A,Fisher RA

更新日期：2004-01-01 00:00:00

abstract：:Cord blood is an attractive cell source in regenerative medicine and represents an alternative to bone marrow. The aim of this study was to investigate whether human umbilical cord blood mononuclear (HUCBM) cells might be valuable in hepatic regenerative medicine. HUCBM cells differentiated in vitro into hepatocytes, ...

journal_title：Cell transplantation

authors： Alvarez-Mercado AI,Sáez-Lara MJ,García-Mediavilla MV,Sánchez-Campos S,Abadía F,Cabello-Donayre M,Gil A,González-Gallego J,Fontana L

更新日期：2008-01-01 00:00:00

abstract：:The need for chronic immune suppression (IS) is one of the hurdles precluding widespread use of islet cell transplantation to restore glycemic control in patients with type 1 diabetes. We report the case of a healthy nonhuman primate (NHP) treated on and off for over 2.5 years with steroid-free IS, consisting of dacli...

journal_title：Cell transplantation

authors： Berman DM,Ruiz P Jr,Blandino-Rosano M,Bernal-Mizrachi E,Kenyon NS

更新日期：2019-03-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is a malignant tumor of the upper aerodigestive tract affecting the oral cavity, lips, paranasal sinuses, larynx, and nasopharynx. Proteogenomics combines proteomics and genomics and employs mass spectrometry and high-throughput sequencing technologies to identify novel pe...

journal_title：Cell transplantation

authors： Wu ZH,Yun-Tang,Cheng Q

更新日期：2020-01-01 00:00:00

abstract：:Maintenance of freshly isolated porcine liver cells in vitro is limited for a short period of time. Therefore, establishment of easy handling cell lines is extremely important for in vitro study for liver cells and their possible utilization for cell differentiation and growth of stem cells. Porcine liver cells were t...

journal_title：Cell transplantation

authors： Shahid JM,Iwamuro M,Sasamoto H,Kubota Y,Seita M,Kawamoto H,Nakaji S,Noguchi H,Yamamoto K,Kobayashi N

更新日期：2010-01-01 00:00:00

abstract：:Although emerging evidence links mesenchymal stem cells (MSCs) with cancer metastasis, the underlying mechanisms are poorly understood. In the present study, we found that human umbilical cord-derived MSCs (UC-MSCs) promoted MCF-7 cell migration in vitro and metastasis in vivo. To explore the mechanisms, the character...

journal_title：Cell transplantation

authors： Ma F,Chen D,Chen F,Chi Y,Han Z,Feng X,Li X,Han Z

更新日期：2015-01-01 00:00:00

abstract：:A newly developed immunosuppressant, FTY720, has a unique mechanism that is quite different from those of conventional immunosuppressants, and is presumed to be mediated through decreases in the number of peripheral lymphocytes, especially helper T cells. This study was performed to ascertain whether this innovative d...

journal_title：Cell transplantation

authors： Yamasaki T,Inoue K,Hayashi H,Gu Y,Setoyama H,Ida J,Cui W,Kawakami Y,Kogire M,Imamura M

更新日期：1998-07-01 00:00:00

abstract：:The requirement for more effective cryopreservation (CP) methodologies in support of the emerging fields of cell bioprocessing and cell therapy is now critical. Current CP strategies appropriately focus on minimizing the damaging actions of physicochemical stressors and membrane disruption associated with extra- and i...

journal_title：Cell transplantation

authors： Baust JM,Vogel MJ,Van Buskirk R,Baust JG

更新日期：2001-01-01 00:00:00

abstract：:Experiments on spinal cord injury (SCI) have largely focused on the transplantation of stem cells into injured spinal cords for motor recovery while neglecting to investigate bladder dysfunction. The present study was performed to investigate the effect of B10 human mesenchymal stem cells (hMSCs) directly transplanted...

journal_title：Cell transplantation

authors： Lee HJ,An J,Doo SW,Kim JH,Choi SS,Lee SR,Park SW,Song YS,Kim SU

更新日期：2015-01-01 00:00:00