The Neuroprotective Effects of Necrostatin-1 on Subarachnoid Hemorrhage in Rats Are Possibly Mediated by Preventing Blood-Brain Barrier Disruption and RIP3-Mediated Necroptosis.

abstract：:Pigs share many anatomical and physiological features with humans, offering a unique and viable model for biomedical research. Although porcine female germline stem cells (FGSCs) were identified in the juvenile ovary, no reports described the isolation and purification of FGSCs from the pig at sexual maturity. Here, w...

journal_title：Cell transplantation

authors： Hou L,Wang J,Li X,Wang H,Liu G,Xu B,Mei X,Hua X,Wu J

更新日期：2018-08-01 00:00:00

abstract：:Gammopathies, multiple myeloma, and amyloidosis are plasma dyscrasias characterized by clonal proliferation and immunoglobulin overproduction. Renal impairment is the most common and serious complication with an incidence of 20-30% patients at the diagnosis. Kidney transplant has not been considered feasible in the pr...

journal_title：Cell transplantation

authors： Baraldi O,Grandinetti V,Donati G,Comai G,Battaglino G,Cuna V,Capelli I,Sala E,La Manna G

更新日期：2016-01-01 00:00:00

abstract：:Hematopoietic stem and progenitor cells reside within the bone marrow (BM) microenvironment. By a well-balanced interplay between self-renewal and differentiation, they ensure a lifelong supply of mature blood cells. Physiologically, multiple different cell types contribute to the regulation of stem and progenitor cel...

journal_title：Cell transplantation

authors： Mattiucci D,Maurizi G,Leoni P,Poloni A

更新日期：2018-05-01 00:00:00

abstract：:The effect of pretreatments of host muscles with metalloproteinases (MMPs) or with notexin on the migration of transplanted myoblasts was investigated. Transgenic TnILacZ mice in which the beta-galactosidase gene is under the control of a quail fast skeletal troponin I gene promoter were used as donors. A polyethylene...

journal_title：Cell transplantation

authors： Torrente Y,El Fahime E,Caron NJ,Bresolin N,Tremblay JP

更新日期：2000-07-01 00:00:00

abstract：:Magnetic targeting has the potential to enhance the therapeutic effects of stem cells through increasing retention of transplanted cells. To investigate the effects of magnetic targeting intensities on cell transplantation, we performed different magnetic intensities for mesenchymal stem cell (MSC)-targeting therapy i...

journal_title：Cell transplantation

authors： Shen Y,Liu X,Huang Z,Pei N,Xu J,Li Z,Wang Y,Qian J,Ge J

更新日期：2015-01-01 00:00:00

abstract：:Ex vivo embryonic liver explant culture is a novel and attractive approach to obtain abundant hepatic and hematopoietic stem cells. Gene therapy of autologous hepatic and hematopoietic stem cells represents an alternative therapeutic approach to liver transplantation for genetic and metabolic disorders. In this study ...

journal_title：Cell transplantation

authors： Monga SPS,Tang Y,Candotti F,Rashid A,Wildner O,Mishra B,Iqbal S,Mishra L

更新日期：2001-01-01 00:00:00

abstract：:Superparamagnetic iron oxide nanoparticles (MNPs) together with magnetic resonance imaging (MRI) are the preferred tools for monitoring the fate and biodistribution of administered cells in stem cell therapy studies. Commercial MNPs need transfection agents and long incubation times for sufficient cell labeling and fu...

journal_title：Cell transplantation

authors： Argibay B,Trekker J,Himmelreich U,Beiras A,Topete A,Taboada P,Pérez-Mato M,Iglesias-Rey R,Sobrino T,Rivas J,Campos F,Castillo J

更新日期：2016-10-01 00:00:00

abstract：:Despite the high prevalence and devastating outcome, there remain a few options for treatment of ischemic stroke. Currently available treatments are limited by a short time window for treatment and marginal efficacy when used. We have tested a human umbilical cord blood-derived stem cell line that has been shown to re...

journal_title：Cell transplantation

authors： Hocum Stone LL,Xiao F,Rotschafer J,Nan Z,Juliano M,Sanberg CD,Sanberg PR,Kuzmin-Nichols N,Grande A,Cheeran MC,Low WC

更新日期：2016-01-01 00:00:00

abstract：:Antibodies to the ligand for CD40 (CD154) have been shown to exert profound effects on the development of cell-mediated immune responses in mice. The present study shows that an antibody to human CD154 (hCD40L) inhibits in vivo Tetanus toxoid (TT) specific secondary antibody responses in hu-PBL-scid mice, as well as t...

journal_title：Cell transplantation

authors： Foy TM,McIlraith M,Masters SR,Dunn JJ,Rossini AA,Shultz LD,Hesselton RA,Wagar EJ,Lipsky PE,Noelle RJ,Greiner DL

更新日期：1998-01-01 00:00:00

abstract：:In human neonates, immature GABAergic interneurons are markedly affected by an excitotoxic insult. While in adults the interest of cell transplantation has been demonstrated in several neurological disorders, few data are available regarding the immature brain. The low survival rate constitutes a strong limitation in ...

journal_title：Cell transplantation

authors： Roux C,Lesueur C,Aligny C,Brasse-Lagnel C,Genty D,Marret S,Laquerrière A,Bekri S,Gonzalez BJ

更新日期：2014-01-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration in the brain and spinal cord. Progressive paralysis of the diaphragm and other respiratory muscles leading to respiratory dysfunction and failure is the most common cause of death in ALS patients. Respiratory impairment has also been s...

journal_title：Cell transplantation

authors： Garbuzova-Davis S,Shell R,Mustafa H,Hailu S,Willing AE,Sanberg PR,Borlongan CV

更新日期：2020-01-01 00:00:00

abstract：:After a unilateral striatal lesion, animals have generally been seen to have a bilateral impairment in paw reaching, with the contralateral paw being more affected. However, most studies to date have not used a pretraining paradigm to assess maximal capacity for paw reaching, to compare with any lesion-induced loss. T...

journal_title：Cell transplantation

authors： Fricker-Gates RA,Smith R,Muhith J,Dunnett SB

更新日期：2003-01-01 00:00:00

abstract：:Recent advances in tissue engineering technologies have highlighted the ability to create functional liver systems using isolated hepatocytes in vivo. Considering the serious shortage of donor livers that can be used for hepatocyte isolation, it has remained imperative to establish a hepatocyte propagation protocol t...

journal_title：Cell transplantation

authors： Ohashi K,Tatsumi K,Tateno C,Kataoka M,Utoh R,Yoshizato K,Okano T

更新日期：2012-01-01 00:00:00

abstract：:To investigate potential cures for spinal cord injury (SCI), several researchers have transplanted neural stem/progenitor cells (NS/PCs) into the injured spinal cord by different procedures, including intralesional (IL), intrathecal (IT), and intravenous (IV) injection. However, there are no reports quantifying or com...

journal_title：Cell transplantation

authors： Takahashi Y,Tsuji O,Kumagai G,Hara CM,Okano HJ,Miyawaki A,Toyama Y,Okano H,Nakamura M

更新日期：2011-01-01 00:00:00

abstract：:Current good manufacturing practice (cGMP) islet processing facilities provide an ultraclean environment for the safe production of clinical grade islets for transplantation into immunosuppressed diabetic recipients. The objective of this study was to monitor the rate of microbial contamination in islet products after...

journal_title：Cell transplantation

authors： Kin T,Rosichuk S,Shapiro AM,Lakey JR

更新日期：2007-01-01 00:00:00

abstract：:Membrane integrity fluorescent staining is used routinely to evaluate islet viability. Results are used as one of the determining factors in islet product release criteria, and are used to assess the efficacy of different culture conditions. Recently, it has been observed that there is variation in the viability stain...

journal_title：Cell transplantation

authors： Barnett MJ,McGhee-Wilson D,Shapiro AM,Lakey JR

更新日期：2004-01-01 00:00:00

abstract：:Investigations indicate that an extract of green tea, polyphenol, can significantly increase the culture survival rate of rat islets without deteriorating their functionality. In this study, we examined the effect of adding polyphenol to islets isolated from human pancreata and nonhuman primate pancreata. Islets were ...

journal_title：Cell transplantation

authors： Zhang G,Matsumoto S,Hyon SH,Qualley SA,Upshaw L,Strong DM,Reems JA

更新日期：2004-01-01 00:00:00

abstract：:Cell escape occurs after intramyocardial injection for treatment of myocardial infarction (MI) and then the migrated cells might be entrapped by extracardiac organs. We investigated the fate of migrated bone marrow-derived mesenchymal stromal cells (MSCs) and their impact on lung, liver, and spleen. MI model was creat...

journal_title：Cell transplantation

authors： Wang W,Jin P,Wang L,Yang Z,Hu S,Gao B,Zhang H

更新日期：2010-01-01 00:00:00

abstract：:A population of Hoechst 33342-stained cells, termed side population (SP) cells, can reconstitute the hematopoietic system of syngeneic mice. This study examined whether limiting numbers of SP cells can repopulate mice across a xenogeneic MHC class I barrier. SP cells were isolated from HLA.B7 and HLA.A2.1 transgenic m...

journal_title：Cell transplantation

authors： Jackson JD,Zhou G,Kuszynski CA,Cai J,Fox IJ

更新日期：2002-01-01 00:00:00

abstract：:Bone marrow-derived cells have different plastic properties, especially regarding cell fusion, which increases with time and is prompted by tissue injury. Several recessive mutations, including Purkinje Cell Degeneration, affect the number of Purkinje cells in homozygosis; heterozygous young animals have an apparently...

journal_title：Cell transplantation

authors： Díaz D,Recio JS,Weruaga E,Alonso JR

更新日期：2012-01-01 00:00:00

abstract：:Neural progenitor cells (NPCs) overexpressing fibroblast growth factor 2 (FGF-2) have the distinct tendency to associate with the vasculature and establish multiple proliferative clusters in the perivascular environment after transplantation into the cerebral cortex. Strikingly, the vascular clusters of progenitor cel...

journal_title：Cell transplantation

authors： Tsupykov O,Kanemitsu M,Smozhanik E,Skibo G,Dayer AG,Kiss JZ

更新日期：2016-01-01 00:00:00

abstract：:Pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, have generated much excitement about their prospects for use in cell transplantation therapies. This is largely attributable to their virtually unlimited growth potential, their ability to be precisely genetically altered ...

journal_title：Cell transplantation

authors： Robinson AJ,Zhao G,Rathjen J,Rathjen PD,Hutchinson RG,Eyre HJ,Hemsley KM,Hopwood JJ

更新日期：2010-01-01 00:00:00

abstract：:Harvesting, expansion, and directed differentiation of human bone marrow-derived mesenchymal stem cells (BM-MSCs) could provide an autologous source of surrogate β-cells that would alleviate the limitations of availability and/or allogenic rejection following pancreatic or islet transplantation. Bone marrow cells were...

journal_title：Cell transplantation

authors： Gabr MM,Zakaria MM,Refaie AF,Ismail AM,Abou-El-Mahasen MA,Ashamallah SA,Khater SM,El-Halawani SM,Ibrahim RY,Uin GS,Kloc M,Calne RY,Ghoneim MA

更新日期：2013-01-01 00:00:00

abstract：:Cord blood is an attractive cell source in regenerative medicine and represents an alternative to bone marrow. The aim of this study was to investigate whether human umbilical cord blood mononuclear (HUCBM) cells might be valuable in hepatic regenerative medicine. HUCBM cells differentiated in vitro into hepatocytes, ...

journal_title：Cell transplantation

authors： Alvarez-Mercado AI,Sáez-Lara MJ,García-Mediavilla MV,Sánchez-Campos S,Abadía F,Cabello-Donayre M,Gil A,González-Gallego J,Fontana L

更新日期：2008-01-01 00:00:00

abstract：:To examine the effects of autologous sural nerve and adrenal medullary tissue intrastriatal cografts upon voluntary motor performance in parkinsonism, a non-human primate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model was employed to quantitatively assess skilled hand movements. Motor performance was studie...

journal_title：Cell transplantation

authors： Watts RL,Mandir AS,Bakay RA

更新日期：1995-01-01 00:00:00

abstract：:Development of β-cells from human embryonic stem cells (hESCs) could compensate for the shortage of islet donors required for diabetes therapy. Although pancreatic progenitors have been derived from hESCs using various protocols, no fully functional b-cells could be generated in vitro. We evaluated the in vivo growth ...

journal_title：Cell transplantation

authors： Sui L,Mfopou JK,Chen B,Sermon K,Bouwens L

更新日期：2013-01-01 00:00:00

abstract：:There is still a lack of sufficient research on the mechanism behind neurogenic bladder (NB) treatment. The aim of this study was to explore the effect of overexpressed stromal cell-derived factor-1 (SDF-1) secreted by engineered immortalized mesenchymal stem cells (imMSCs) on the NB. In this study, primary bone marro...

journal_title：Cell transplantation

authors： Zhu GQ,Jeon SH,Lee KW,Cho HJ,Ha US,Hong SH,Lee JY,Kwon EB,Kim HJ,Lee SM,Kim HY,Kim SW,Bae WJ

更新日期：2020-01-01 00:00:00

abstract：:Myoblast transplantation is being considered as a potential strategy to improve muscle function in myopathies; hence, it is important to identify the transplanted cells and to have available efficient reagents to track these cells. We first validated a human to mouse xenotransplantation model warranting the complete a...

journal_title：Cell transplantation

authors： Praud C,Vauchez K,Lombes A,Fiszman MY,Vilquin JT

更新日期：2008-01-01 00:00:00

abstract：:Adipose tissue contains a mesenchymal stem cell (MSC) population known as adipose-derived stem cells (ASCs) capable of differentiating into different cell types. Our aim was to induce hepatic transdifferentiation of ASCs by sequential exposure to several combinations of cytokines, growth factors, and hormones. The mos...

journal_title：Cell transplantation

authors： Bonora-Centelles A,Jover R,Mirabet V,Lahoz A,Carbonell F,Castell JV,Gómez-Lechón MJ

更新日期：2009-01-01 00:00:00

abstract：:Recently, we described a diffusion chamber for a bioartificial endocrine pancreas (Bio-AEP). Pancreatic islet cells in the Bio-AEP device were isolated from the immune system of the host by an artificial barrier, while nutrients, electrolytes, oxygen, and bioactive secretory products were exchanged across this barrier...

journal_title：Cell transplantation

authors： Hirotani S,Eda R,Kawabata T,Fuchinoue S,Teraoka S,Agishi T,Ohgawara H

更新日期：1999-07-01 00:00:00