Polyphenol, an extract of green tea, increases culture recovery rates of isolated islets from nonhuman primate pancreata and marginal grade human pancreata.

abstract：:It is currently said that CO has anti-inflammatory and antiapoptosis effects and it has attracted attention as a medical gas. We used CO for rat hearts and conducted a preservation experiment. We isolated rat hearts, placed them into a specially made chamber, filled the chamber with a gas mixture of PCO (4,000 hPa) a...

journal_title：Cell transplantation

authors： Hatayama N,Naito M,Hirai S,Yoshida Y,Kojima T,Seki K,Li XK,Itoh M

更新日期：2012-01-01 00:00:00

abstract：:Stem cell-based therapy shows great potential in stroke patients. Intra-artery infusion exhibits greater biological distribution compared to intravenous delivery. In addition, umbilical cord mesenchymal stem cells (UCMSCs) have several advantages compared with other types of stem cells. The aim of this study was to ev...

journal_title：Cell transplantation

authors： Jiang Y,Zhu W,Zhu J,Wu L,Xu G,Liu X

更新日期：2013-01-01 00:00:00

abstract：:Endostatin (ES) is a potent inhibitor of angiogenesis and tumor growth. Continuous ES delivery of ES improves the efficacy and potency of the antitumoral therapy. The TheraCyte system is a polytetrafluoroethylene (PTFE) semipermeable membrane macroencapsulation system for implantation of genetically engineered cells s...

journal_title：Cell transplantation

authors： Malavasi NV,Rodrigues DB,Chammas R,Chura-Chambi RM,Barbuto JA,Balduino K,Nonogaki S,Morganti L

更新日期：2010-01-01 00:00:00

abstract：:Stroke is the third leading cause of death worldwide and a huge perpetrator in adult disability. This pilot clinical study investigates the possible benefits of transplanting multiple cells in chronic stroke. A total of 10 consecutive stroke patients were treated by combination cell transplantation on the basis of an ...

journal_title：Cell transplantation

authors： Chen L,Xi H,Huang H,Zhang F,Liu Y,Chen D,Xiao J

更新日期：2013-01-01 00:00:00

abstract：:Neuronal progenitor cells (NPCs) derived from human embryonic stem cells (hESCs) are an excellent cell source for transplantation therapy due to their availability and ethical acceptability. However, the traditional method of expansion and differentiation of hESCs into NPCs in monolayer cultures requires a long time, ...

journal_title：Cell transplantation

authors： Qiu L,Lim YM,Chen AK,Reuveny S,Oh SK,Tan EK,Zeng L

更新日期：2016-01-01 00:00:00

abstract：:Testis-derived Sertoli cells have been used to create an immune "privileged" site outside of the testis to facilitate cell transplantation protocols for diabetes and neurodegenerative diseases. In addition to secreting immunoprotective factors, Sertoli cells also secrete growth and trophic factors that appear to enhan...

journal_title：Cell transplantation

authors： Cameron DF,Othberg AI,Borlongan CV,Rashed S,Anton A,Saporta S,Sanberg PR

更新日期：1997-03-01 00:00:00

abstract：:Multiple system atrophy (MSA) is a neurodegenerative disorder that occurs sporadically and causes parkinsonism, cerebellar, autonomic, urinary, and pyramidal dysfunction in many combinations. Progressive L-dopa-unresponsive parkinsonism due to underlying striatonigral degeneration dominates the clinical syndrome in th...

journal_title：Cell transplantation

authors： Wenning GK,Tison F,Scherfler C,Puschban Z,Waldner R,Granata R,Ghorayeb I,Poewe W

更新日期：2000-03-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) may be of value in regeneration of renal tissue after damage; however, lack of biological knowledge and variability of results in animal models limit their utilization. We studied the effects of MSCs on podocytes in vitro and in vivo utilizing adriamycin (ADR) as a model of renal toxicity...

journal_title：Cell transplantation

authors： Magnasco A,Corselli M,Bertelli R,Ibatici A,Peresi M,Gaggero G,Cappiello V,Chiavarina B,Mattioli G,Gusmano R,Ravetti JL,Frassoni F,Ghiggeri GM

更新日期：2008-01-01 00:00:00

abstract：:Pancreas procurement for islet isolation and transplantation is limited by concerns for the detrimental effects of postmortem ischemia. Hypothermic machine perfusion (HMP) preservation technology has had a major impact in circumventing ischemic injury in clinical kidney transplantation and is applied here to the prese...

journal_title：Cell transplantation

authors： Taylor MJ,Baicu S,Greene E,Vazquez A,Brassil J

更新日期：2010-01-01 00:00:00

abstract：:Techniques for medical tissue regeneration require an abundant source of human adult stem cells. There is increasing evidence that adipose stem cells contribute to restoration of tissue vascularization and organ function. The object of our study was to isolate and characterize adult adipose-derived stem cells from pat...

journal_title：Cell transplantation

authors： Folgiero V,Migliano E,Tedesco M,Iacovelli S,Bon G,Torre ML,Sacchi A,Marazzi M,Bucher S,Falcioni R

更新日期：2010-01-01 00:00:00

abstract：:The development of cell- and gene-based strategies for regenerative medicine offers a therapeutic option for the repair and potential regeneration of damaged cardiac tissue post-myocardial infarction (MI). Human umbilical cord subepithelial cell-derived stem cells (hUC-SECs), human bone marrow-derived mesenchymal stem...

journal_title：Cell transplantation

authors： Winters AA,Bou-Ghannam S,Thorp H,Hawayek JA,Atkinson DL,Bartlett CE,Silva FJ,Hsu EW,Moreno AP,Grainger DA,Patel AN

更新日期：2016-01-01 00:00:00

abstract：:Despite the substantial efforts to elucidate the role of early brain injury in subarachnoid hemorrhage (SAH), an effective pharmaceutical therapy for patients with SAH continues to be unavailable. This study aims to reveal the role of necroptosis after SAH, and explore whether the disruption of the blood-brain barrier...

journal_title：Cell transplantation

authors： Chen J,Jin H,Xu H,Peng Y,Jie L,Xu D,Chen L,Li T,Fan L,He P,Ying G,Gu C,Wang C,Wang L,Chen G

更新日期：2019-11-01 00:00:00

abstract：:The aim of this work was to determine the effect of nicotine desensitization on dopamine (DA) release in the dorsal striatum and shell of the nucleus accumbens (NAc) from brain slices. In vitro fast-scan cyclic voltammetry analysis was used to evaluate dopamine release in the dorsal striatum and the NAc shell of Sprag...

journal_title：Cell transplantation

authors： Chen YH,Lin BJ,Hsieh TH,Kuo TT,Miller J,Chou YC,Huang EY,Hoffer BJ

更新日期：2019-03-01 00:00:00

abstract：:Maintenance of freshly isolated porcine liver cells in vitro is limited for a short period of time. Therefore, establishment of easy handling cell lines is extremely important for in vitro study for liver cells and their possible utilization for cell differentiation and growth of stem cells. Porcine liver cells were t...

journal_title：Cell transplantation

authors： Shahid JM,Iwamuro M,Sasamoto H,Kubota Y,Seita M,Kawamoto H,Nakaji S,Noguchi H,Yamamoto K,Kobayashi N

更新日期：2010-01-01 00:00:00

abstract：:During the isolation of human islets of Langerhans the digest has repeated direct contact with the ambient atmosphere. In order to fulfill GMP requirements in clinical applications, the entire cell preparation must be performed in clean room facilities. We hypothesized that the use of a closed system, which avoids the...

journal_title：Cell transplantation

authors： Klaffschenkel RA,Biesemeier A,Waidmann M,Northoff H,Steurer W,Königsrainer A,Lembert N

更新日期：2007-01-01 00:00:00

abstract：:Human skin contains keratinocytes in the epidermis. Such cells share their ectodermal origin with the central nervous system (CNS). Recent studies have demonstrated that terminally differentiated somatic cells can adopt a pluripotent state, or can directly convert its phenotype to neurons, after ectopic expression of ...

journal_title：Cell transplantation

authors： Tenorio-Mina A,Cortés D,Esquivel-Estudillo J,López-Ornelas A,Cabrera-Wrooman A,Lara-Rodarte R,Escobedo-Avila I,Vargas-Romero F,Toledo-Hernández D,Estudillo E,Acevedo-Fernández JJ,Tapia JS,Velasco I

更新日期：2021-01-01 00:00:00

abstract：:Islet isolation involves enzymatic digestion of the interstitial matrix and mechanical disruption of the tissue. It is possible that a fundamental change of islet biology resulting from the loss of critical factors required for islet function or survival will occur. Extracellular matrix (ECM) is one of the most import...

journal_title：Cell transplantation

authors： Nagata N,Gu Y,Hori H,Balamurugan AN,Touma M,Kawakami Y,Wang W,Baba TT,Satake A,Nozawa M,Tabata Y,Inoue K

更新日期：2001-01-01 00:00:00

abstract：:Stem cells from dental tissues have been isolated and established for tooth regenerative applications. However, basic characterization on their biological properties still needs to be investigated before employing them for effective clinical trials. In this study, we compared the telomere length, relative telomerase ...

journal_title：Cell transplantation

authors： Jeon BG,Kang EJ,Kumar BM,Maeng GH,Ock SA,Kwack DO,Park BW,Rho GJ

更新日期：2011-01-01 00:00:00

abstract：:The formation of a new microvasculature is essential for the long-term survival and function of the islet graft. In this study we examined endothelium of isolated pancreatic islets by stimulation with growth factors, different culture conditions, and genetic modification. We also inspected the effect of immunosuppress...

journal_title：Cell transplantation

authors： Kidszun A,Schneider D,Erb D,Hertl G,Schmidt V,Eckhard M,Preissner KT,Breier G,Bretzel RG,Linn T

更新日期：2006-01-01 00:00:00

abstract：:For isolated pancreatic islet cell preparations, it is important to be able to reliably assess their mass and quality, and for clinical applications, it is part of the regulatory requirement. Accurate assessment, however, is difficult because islets are spheroid-like cell aggregates of different sizes (<50 to 500 μm) ...

journal_title：Cell transplantation

authors： Buchwald P,Bernal A,Echeverri F,Tamayo-Garcia A,Linetsky E,Ricordi C

更新日期：2016-10-01 00:00:00

abstract：:The present study was designed to evaluate the use of collagen gel loaded with human retinal pigment epithelium (ARPE19) in cellular transfer and to assess its viability within the gel. Collagen solution was prepared by dissolving calfskin in hydrochloric acid to make a final concentration of 2.0 mg/ml and this was mi...

journal_title：Cell transplantation

authors： Yeung CK,Chiang SW,Chan KP,Lam DS,Pang CP

更新日期：2004-01-01 00:00:00

abstract：:Critical length nerve defects in the rat sciatic nerve model were reconstructed with chitosan nerve guides filled with Schwann cells (SCs) containing hydrogel. The transplanted SCs were naive or had been genetically modified to overexpress neurotrophic factors, thus providing a cellular neurotrophic factor delivery sy...

journal_title：Cell transplantation

authors： Meyer C,Wrobel S,Raimondo S,Rochkind S,Heimann C,Shahar A,Ziv-Polat O,Geuna S,Grothe C,Haastert-Talini K

更新日期：2016-01-01 00:00:00

abstract：:In cartilage tissue engineering using stem cells, it is important to stimulate proliferation and control the differentiation of stem cells to specific lineages. Here we reported a combined technique for articular cartilage repair, consisting of bone marrow mesenchymal stem cells (BMMSCs) transfected with connective ti...

journal_title：Cell transplantation

authors： Zhu S,Zhang B,Man C,Ma Y,Liu X,Hu J

更新日期：2014-04-01 00:00:00

abstract：:Human embryonic stem (hES) cells have the ability to differentiate into a variety of different cell lineages and potentially provide a source of differentiated cells for many therapeutic uses. Here we investigated an efficient method of hepatic differentiation from hES cells. A human ES cell line, KhES-1, was used and...

journal_title：Cell transplantation

authors： Chen Y,Soto-Gutierrez A,Navarro-Alvarez N,Rivas-Carrillo JD,Yamatsuji T,Shirakawa Y,Tanaka N,Basma H,Fox IJ,Kobayashi N

更新日期：2006-01-01 00:00:00

abstract：:At present, there are still significant barriers that impede the clinical use of hESCs and iPS cells, including ethics, immunorejection, tumorigenesis from hESCs, and teratoma formation from iPS cells. It is therefore necessary to search for alternative sources of stem cells. WJ-MSCs originate from embryonic epiblasts...

journal_title：Cell transplantation

authors： Gao LR,Zhang NK,Ding QA,Chen HY,Hu X,Jiang S,Li TC,Chen Y,Wang ZG,Ye Y,Zhu ZM

更新日期：2013-01-01 00:00:00

abstract：:Liver cell transplantation into host organs like the spleen may possibly provide a temporary relief after extensive liver resection or severe liver disease or may enable treatment of an enzyme deficiency. With time, however, dedifferentiation or malignant transformation of the ectopically transplanted cells may be pos...

journal_title：Cell transplantation

authors： Lupp A,Danz M,Müller D

更新日期：2003-01-01 00:00:00

abstract：:It is difficult to normalize plasma glucose for a prolonged period of time by s.c. injection in experimental animals. The goal of this study was to determine the feasibility and the dosage of insulin needed to maintain 24-h normoglycemia in streptozotocin-diabetic Syrian hamsters with a s.c.-implanted osmotic minipump...

journal_title：Cell transplantation

authors： Fisher WE

更新日期：1999-09-01 00:00:00

abstract：:Traumatic brain injury (TBI), a major contributor to deaths and permanent disability worldwide, has been recently described as a progressive cell death process rather than an acute event. TBI pathophysiology is complicated and can be distinguished by the initial primary injury and the subsequent secondary injury that ...

journal_title：Cell transplantation

authors： De La Peña I,Sanberg PR,Acosta S,Lin SZ,Borlongan CV

更新日期：2015-01-01 00:00:00

abstract：:The anatomical specificity of axon growth from fetal pig septal xenografts was studied by transplanting septal cells from E30-35 pig fetuses into cholinergic deafferented (192-IgG-saporin-infused) rats or into aged rats (> 18 months). Cell suspensions (100,000 cells/microl) were injected bilaterally into the dorsal an...

journal_title：Cell transplantation

authors： Deacon T,Whatley B,LeBlanc C,Lin L,Isacson O

更新日期：1999-01-01 00:00:00

abstract：:The neurorestorative effects of exogenous neurturin (NTN) delivered directly into the putamen via multiport catheters were studied in 10 MPTP-lesioned rhesus monkeys expressing stable parkinsonism. The parkinsonian animals were blindly assigned to receive coded solutions containing either vehicle (n = 5) or NTN (n = 5...

journal_title：Cell transplantation

authors： Grondin R,Zhang Z,Ai Y,Ding F,Walton AA,Surgener SP,Gerhardt GA,Gash DM

更新日期：2008-01-01 00:00:00