Engineered Stem Cells Improve Neurogenic Bladder by Overexpressing SDF-1 in a Pelvic Nerve Injury Rat Model.

abstract：:Near infrared fluorescence (NIRF) optical imaging is a technique particularly powerful when studying in vivo processes at the molecular level in preclinical animal models. We recently demonstrated liver irradiation under the additional stimulus of partial hepatectomy as being an effective primer in the rat liver repop...

journal_title：Cell transplantation

authors： Koenig S,Krause P,Hosseini AS,Dullin C,Rave-Fraenk M,Kimmina S,Entwistle AL,Hermann RM,Hess CF,Becker H,Christiansen H

更新日期：2009-01-01 00:00:00

abstract：:The biohybrid artificial pancreas is designed to enclose pancreatic tissues with a selectively permeable membrane that immunoisolates the graft from the host immune system, allowing those endocrine tissues to survive and control glucose metabolism for an extended period of time. The pancreatic B cell line MIN6 is esta...

journal_title：Cell transplantation

authors： Kawakami Y,Inoue K,Hayashi H,Wang WJ,Setoyama H,Gu YJ,Imamura M,Iwata H,Ikada Y,Nozawa M,Miyazaki J

更新日期：1997-09-01 00:00:00

abstract：:The development of new cell replacement strategies using neural stem cells (NSC) may provide an alternative and unlimited cell source for clinical neural transplantation in neurodegenerative diseases such as Parkinson's and Huntington's disease. The clinical application of neural transplantation using NSC will therefo...

journal_title：Cell transplantation

authors： McLeod M,Hong M,Sen A,Sadi D,Ulalia R,Behie LA,Mendez I

更新日期：2006-01-01 00:00:00

abstract：:Epithelial wound repair assures the recovery of the epithelial barrier after wounding. During wound healing epithelial cells migrate to cover the wound surface. The presented experiments were carried out to compare the migration of human keratinocytes from primary and secondary culture on polystyrene, collagen, and fi...

journal_title：Cell transplantation

authors： Drukała J,Bandura L,Cieślik K,Korohoda W

更新日期：2001-01-01 00:00:00

abstract：:Despite the substantial efforts to elucidate the role of early brain injury in subarachnoid hemorrhage (SAH), an effective pharmaceutical therapy for patients with SAH continues to be unavailable. This study aims to reveal the role of necroptosis after SAH, and explore whether the disruption of the blood-brain barrier...

journal_title：Cell transplantation

authors： Chen J,Jin H,Xu H,Peng Y,Jie L,Xu D,Chen L,Li T,Fan L,He P,Ying G,Gu C,Wang C,Wang L,Chen G

更新日期：2019-11-01 00:00:00

abstract：:Cord blood is an attractive cell source in regenerative medicine and represents an alternative to bone marrow. The aim of this study was to investigate whether human umbilical cord blood mononuclear (HUCBM) cells might be valuable in hepatic regenerative medicine. HUCBM cells differentiated in vitro into hepatocytes, ...

journal_title：Cell transplantation

authors： Alvarez-Mercado AI,Sáez-Lara MJ,García-Mediavilla MV,Sánchez-Campos S,Abadía F,Cabello-Donayre M,Gil A,González-Gallego J,Fontana L

更新日期：2008-01-01 00:00:00

abstract：:Isolation of islets from market-sized pigs is costly, with considerable islet losses from fragmentation occurring during isolation and tissue culture. Fetal and neonatal pigs yield insulin unresponsive islet-like cell clusters that become glucose-responsive after extended periods of time. Both issues impact clinical a...

journal_title：Cell transplantation

authors： Lamb M,Laugenour K,Liang O,Alexander M,Foster CE,Lakey JR

更新日期：2014-03-01 00:00:00

abstract：:In a companion article, we describe the engineering and characterization of pituitary GH3 cell clones stably transfected with a furin-cleavable human insulin cDNA (InsGH3 cells). This article describes the performance of InsGH3 (clones 1 and 7) cell grafts into streptozotocin (STZ)-induced diabetic nude mice. Subcutan...

journal_title：Cell transplantation

authors： Davalli AM,Galbiati F,Bertuzzi F,Polastri L,Pontiroli AE,Perego L,Freschi M,Pozza G,Folli F,Meoni C

更新日期：2000-11-01 00:00:00

abstract：:Insufficient oxygenation can limit the long-term survival of encapsulated islets in subcutaneous tissue. Transplantation of coencapsulated pig islets with adipose or bone marrow mesenchymal stem cells (AMSCs or BM-MSCs, respectively) was investigated with regard to implant vascularization, oxygenation, and diabetes co...

journal_title：Cell transplantation

authors： Vériter S,Gianello P,Igarashi Y,Beaurin G,Ghyselinck A,Aouassar N,Jordan B,Gallez B,Dufrane D

更新日期：2014-01-01 00:00:00

abstract：:During in vivo intracerebral infusions, the ability to perform accurate targeting towards a 3D-specific point allows control of the anatomical variable and identification of the effects of variations in other factors. Intraoperative MRI navigation systems are currently being used in the clinic, yet their use in nonhum...

journal_title：Cell transplantation

authors： Emborg ME,Joers V,Fisher R,Brunner K,Carter V,Ross C,Raghavan R,Brady M,Raschke J,Kubota K,Alexander A

更新日期：2010-01-01 00:00:00

abstract：:During the isolation of human islets of Langerhans the digest has repeated direct contact with the ambient atmosphere. In order to fulfill GMP requirements in clinical applications, the entire cell preparation must be performed in clean room facilities. We hypothesized that the use of a closed system, which avoids the...

journal_title：Cell transplantation

authors： Klaffschenkel RA,Biesemeier A,Waidmann M,Northoff H,Steurer W,Königsrainer A,Lembert N

更新日期：2007-01-01 00:00:00

abstract：:One of the serious obstacles of the aortopathies research is a considerable shortage of human aortic smooth muscle cells (SMCs), which can be used to model the disease. SMC in most cases come from the whole aorta of transplant donors, which are rather difficult to access. In the course of coronary artery bypass graft ...

journal_title：Cell transplantation

authors： Kostina D,Zverev D,Grebennik V,Gordeev M,Ignatieva E,Voronkina I,Kostareva A,Malashicheva A

更新日期：2017-10-01 00:00:00

abstract：:Parkinson's disease (PD), while primarily associated with degeneration of nigrostriatal dopamine neurons, is now increasingly recognized to have more widespread cell loss and so the most effective cell replacement therapy should target all these neuronal losses. Neural precursor cells might be ideal in this regard as ...

journal_title：Cell transplantation

authors： Jain M,Armstrong RJ,Elneil S,Barker RA

更新日期：2006-01-01 00:00:00

abstract：:Testicular germ cell tumors (TGCTs) are highly prevalent in young men aged 20-40 years and are one of the most common lethal solid tumors in men of this age. Due to the current unclear mechanism of tumor development, there is a lack of effective treatment, and therefore in-depth research of the molecular mechanism of ...

journal_title：Cell transplantation

authors： Luo Y,Sun Y,Li L,Mao Y

更新日期：2020-01-01 00:00:00

abstract：:Nonhuman primate models of Parkinson's disease (PD) have been invaluable to our understanding of the human disease and in the advancement of novel therapies for its treatment. In this review, we attempt to give a brief overview of the animal models of PD currently used, with a more comprehensive focus on the advantage...

journal_title：Cell transplantation

authors： Soderstrom K,O'Malley J,Steece-Collier K,Kordower JH

更新日期：2006-01-01 00:00:00

abstract：:Wharton's jelly-derived mesenchymal stromal cells (WJ-MSCs) have distinct immunomodulatory and protective effects against kidney, liver, or heart injury. Limited studies have shown that WJ-MSCs attenuates oxygen-glucose deprivation-mediated inflammation in hippocampal slices. The neuroprotective effect of intracerebra...

journal_title：Cell transplantation

authors： Wu KJ,Yu SJ,Chiang CW,Lee YW,Yen BL,Tseng PC,Hsu CS,Kuo LW,Wang Y

更新日期：2018-11-01 00:00:00

abstract：:Sepsis is a life-threatening disease that results in excessive stimulation of the host's immune cells. In the animal study, the purpose was to investigate the roles of fresh frozen plasma (FFP) transfusion in shaping the CD4+ T lymphocytes immune response through modulating the secreted exosome protein Galectin-9 in m...

journal_title：Cell transplantation

authors： Zhang L,Zhang JP,Liu Y,Wang H,Cheng Y,Wang JH,Zhang WJ,Li ZZ,Guo JR

更新日期：2020-01-01 00:00:00

abstract：:Persistent corneal wounds result from numerous eye disorders, and to date, available treatments often fail to accelerate reepithelialization, the key initial step in wound healing. To speed reepithelialization, we explored a cell-transfer transplant method utilizing polydimethylsiloxane (PDMS) contact lenses to delive...

journal_title：Cell transplantation

authors： Pino CJ,Haselton FR,Chang MS

更新日期：2005-01-01 00:00:00

abstract：:The aim of this work was to determine the effect of nicotine desensitization on dopamine (DA) release in the dorsal striatum and shell of the nucleus accumbens (NAc) from brain slices. In vitro fast-scan cyclic voltammetry analysis was used to evaluate dopamine release in the dorsal striatum and the NAc shell of Sprag...

journal_title：Cell transplantation

authors： Chen YH,Lin BJ,Hsieh TH,Kuo TT,Miller J,Chou YC,Huang EY,Hoffer BJ

更新日期：2019-03-01 00:00:00

abstract：:Possible strategies for treating stroke include: 1) thrombolytic therapy with tissue plasminogen activator (tPA): restoring cerebral blood flow in the acute phase of ischemic stroke but sometimes causing hemorrhagic transformation (HT); 2) stem cell therapy: the repair of disrupted neuronal networks with newly born ne...

journal_title：Cell transplantation

authors： Yamashita T,Deguchi K,Nagotani S,Abe K

更新日期：2011-01-01 00:00:00

abstract：:The periodontal ligament displays a reservoir of mesenchymal stem cells which can account for periodontal regeneration. Despite the numerous studies directed at the definition of optimal culture conditions for long-term expansion of periodontal ligament stem cells (PDLSCs), no consensus has been reached as to what is ...

journal_title：Cell transplantation

authors： Di Vito A,Giudice A,Chiarella E,Malara N,Bennardo F,Fortunato L

更新日期：2019-01-01 00:00:00

abstract：:The revascularization of islets of Langerhans transplanted in heterotopic sites like the liver by portal vein embolization or the renal subcapsular space is a major process necessary for the viability of grafted cells. This process has been extensively studied by different techniques and the results have shown that is...

journal_title：Cell transplantation

authors： Mendola JF,Conget I,Manzanares JM,Corominola H,Viñas O,Barcelo J,Gomis R

更新日期：1997-11-01 00:00:00

abstract：:Expression of a fluorescent reporter gene has been studied using two alternate promoters to transcribe the green fluorescent protein (gfp) from Aequorea victoria. The human cytomegalovirus (CMV) enhancer/ promoter or the human muscle-specific creatine kinase promoter (CKM) were inserted along with the gfp cDNA into a ...

journal_title：Cell transplantation

authors： Bartlett RJ,Secore SL,Singer JT,Bodo M,Sharma K,Ricordi C

更新日期：1996-05-01 00:00:00

abstract：:Cellular transplantation strategies utilizing intraspinal or intrathecal olfactory ensheathing cells (OECs) have been reported as beneficial for spinal cord injury (SCI). However, there are many disadvantages of these methods, including additional trauma to the spinal cord parenchyma and technical challenges. Therefor...

journal_title：Cell transplantation

authors： Zhang L,Zhuang X,Chen Y,Xia H

更新日期：2019-12-01 00:00:00

abstract：:Astrocytes protection and functional regulation are important strategies to protect against neuronal damage caused by ischemia. Activation of the delta opioid receptor (DOR) could reduce astrocytes damage, although the mechanism remains unclear. The present study aimed to test the effect of DOR activation on autophagy...

journal_title：Cell transplantation

authors： Wang S,Cao X,Duan Y,Zhang G

更新日期：2019-06-01 00:00:00

abstract：:The integrity of the blood-brain barrier (BBB) plays a vital role in affecting the prognosis of subarachnoid hemorrhage (SAH). This study aimed to investigate activation of the Tropomyosin-related kinase receptor B (TrkB) and its downstream signaling pathway on preserving BBB breakdown after experimental SAH. An endov...

journal_title：Cell transplantation

authors： Qi X,Liu J,Wu J,Bi Y,Han C,Zhang G,Lou M,Lu J,Tang J

更新日期：2019-08-01 00:00:00

abstract：:Hematopoietic stem and progenitor cells reside within the bone marrow (BM) microenvironment. By a well-balanced interplay between self-renewal and differentiation, they ensure a lifelong supply of mature blood cells. Physiologically, multiple different cell types contribute to the regulation of stem and progenitor cel...

journal_title：Cell transplantation

authors： Mattiucci D,Maurizi G,Leoni P,Poloni A

更新日期：2018-05-01 00:00:00

abstract：:The limited availability of human embryonic tissue for dopamine cell transplants in Parkinson's patients has led to an increased interest in using xenogeneic donor tissue. Unfortunately, without aggressive immunosuppression, such brain xenografts are rejected by the host immune system. Chronic brain xenograft rejectio...

journal_title：Cell transplantation

authors： Veng LM,Bjugstad KB,Freed CR,Marrack P,Clarkson ED,Bell KP,Hutt C,Zawada WM

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to evaluate the qualitative change in reparative cartilage after autologous chondrocyte implantation (ACI). Ten knees of 10 patients were studied. The signal intensities of reparative and normal cartilage were evaluated by fat-suppressed three-dimensional spoiled-gradient recalled (FS 3D-SPGR...

journal_title：Cell transplantation

authors： Watanabe A,Wada Y,Obata T,Sasho T,Ueda T,Tamura M,Ikehira H,Moriya H

更新日期：2005-01-01 00:00:00

abstract：:Peripheral blood samples from HIV-seropositive individuals enrolled in a pilot clinical trial investigating the use of allogeneic dendritic cell therapy were evaluated for mixed chimerism. In this study, dendritic cells from HLA-identical, HIV-seronegative siblings were used. Patients received an infusion of dendritic...

journal_title：Cell transplantation

authors： Shapero MH,Kundu SK,Engleman E,Laus R,van Schooten WC,Merigan TC

更新日期：2000-05-01 00:00:00