Locomotion of human skin keratinocytes on polystyrene, fibrin, and collagen substrata and its modification by cell-to-cell contacts.

abstract：:The neurorestorative effects of exogenous neurturin (NTN) delivered directly into the putamen via multiport catheters were studied in 10 MPTP-lesioned rhesus monkeys expressing stable parkinsonism. The parkinsonian animals were blindly assigned to receive coded solutions containing either vehicle (n = 5) or NTN (n = 5...

journal_title：Cell transplantation

authors： Grondin R,Zhang Z,Ai Y,Ding F,Walton AA,Surgener SP,Gerhardt GA,Gash DM

更新日期：2008-01-01 00:00:00

abstract：:In this study, we assessed the ability of miR-26b-5p to regulate T cell factor 4 (TCF-4) expression and thereby control human adipose-derived mesenchymal stem cell (hADMSC) adipogenic differentiation. Adipogenic medium was used to induce hADMSC differentiation over a 6-d period. The ability of miR-26b-5p to interact w...

journal_title：Cell transplantation

authors： Luo Y,Ji H,Cao Y,Ding X,Li M,Song H,Li S,WaTableng C,Wu H,Meng J,Du H

更新日期：2020-01-01 00:00:00

abstract：:Stem cells from dental tissues have been isolated and established for tooth regenerative applications. However, basic characterization on their biological properties still needs to be investigated before employing them for effective clinical trials. In this study, we compared the telomere length, relative telomerase ...

journal_title：Cell transplantation

authors： Jeon BG,Kang EJ,Kumar BM,Maeng GH,Ock SA,Kwack DO,Park BW,Rho GJ

更新日期：2011-01-01 00:00:00

abstract：:Hepatocyte transplantation (HT) has become an effective therapy for patients with metabolic inborn errors. We report the clinical outcome of four children with metabolic inborn errors that underwent HT, describing the cell infusion protocol and the metabolic outcome of transplanted patients. Cryopreserved hepatocytes...

journal_title：Cell transplantation

authors： Ribes-Koninckx C,Ibars EP,Calzado Agrasot MÁ,Bonora-Centelles A,Miquel BP,Vila Carbó JJ,Aliaga ED,Pallardó JM,Gómez-Lechón MJ,Castell JV

更新日期：2012-01-01 00:00:00

abstract：:In adults, hematopoiesis takes places in the bone marrow, where specialized niches containing mesenchymal nonhematopoietic cells (stroma) harbor the hematopoietic stem cell (HSC). These niches are responsible and essential for the maintenance of HSCs. Attempts to expand HSCs fail to keep the general properties of ste...

journal_title：Cell transplantation

authors： Paraguassú-Braga FH,Alves AP,Santos IM,Bonamino M,Bonomo A

更新日期：2012-01-01 00:00:00

abstract：:Functional demands on a bioartificial liver support (BAL) device are not limited to biosynthetic activities, but must also encompass metabolic removal of potentially toxic substances. For most BALs, however, the concept and design are exclusively directed to biosynthetic support. To add the ability to metabolize and r...

journal_title：Cell transplantation

authors： Takahashi M,Sakurai M,Enosawa S,Omasa T,Tsuruoka S,Matsumura T

更新日期：2006-01-01 00:00:00

abstract：:The use of biomaterials has been demonstrated as a viable strategy to promote cell survival and cardiac repair. However, limitations on combinational cell-biomaterial therapies exist, as cellular behavior is influenced by the microenvironment and physical characteristics of the material. Among the different scaffolds ...

journal_title：Cell transplantation

authors： Gaetani R,Yin C,Srikumar N,Braden R,Doevendans PA,Sluijter JP,Christman KL

更新日期：2016-01-01 00:00:00

abstract：:The aim of this work was to determine the effect of nicotine desensitization on dopamine (DA) release in the dorsal striatum and shell of the nucleus accumbens (NAc) from brain slices. In vitro fast-scan cyclic voltammetry analysis was used to evaluate dopamine release in the dorsal striatum and the NAc shell of Sprag...

journal_title：Cell transplantation

authors： Chen YH,Lin BJ,Hsieh TH,Kuo TT,Miller J,Chou YC,Huang EY,Hoffer BJ

更新日期：2019-03-01 00:00:00

abstract：:There has been no gold standard for intraoperative monitoring in carotid endarterectomy (CEA) till now. The purpose of the current study was to investigate the value of near-infrared spectroscopy (NIRS) monitoring in CEA and explore the thresholds for intraoperative cerebral hypoperfusion. Eighty-four consecutive pati...

journal_title：Cell transplantation

authors： Wang Y,Li L,Wang T,Zhao L,Feng H,Wang Q,Fan L,Feng X,Xiao W,Feng K

更新日期：2019-02-01 00:00:00

abstract：:Hepatocyte-based biological therapies are increasingly envisioned for temporary support in acute liver failure and provision of specific-liver functions in liver-based metabolic deficiency. One of the hurdles to develop such therapies is severe shortage of human livers for hepatocyte isolation. To address the issue, w...

journal_title：Cell transplantation

authors： Kobayashi N,Tanaka N

更新日期：2002-07-01 00:00:00

abstract：:We examined a possible protective effect of the nonpeptidyl low molecular weight radical scavenger IAC [bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decanedioate di-hydrochloride] on isolated human islet cells against isolation and culture oxidative stress. Islets isolated from pancreases of nondiabetic multiorgan ...

journal_title：Cell transplantation

authors： Mancarella R,Del Guerra S,Masini M,Bugliani M,Valgimigli L,Pedulli GF,Paolini M,Canistro D,Armando A,Soleti A,Filipponi F,Mosca F,Boggi U,Del Prato S,Marchetti P,Lupi R

更新日期：2008-01-01 00:00:00

abstract：:Prairie voles show strong pair bonding with their mating partners, and they demonstrate parental behavior toward their infants, indicating that the prairie vole is a unique animal model for analysis of molecular mechanisms of social behavior. Until a recent study, the signaling pathway of oxytocin was thought to be cr...

journal_title：Cell transplantation

authors： Katayama M,Hirayama T,Horie K,Kiyono T,Donai K,Takeda S,Nishimori K,Fukuda T

更新日期：2016-01-01 00:00:00

abstract：:Porcine neonatal islet-like cell clusters (NICCs) may be an attractive source of insulin-producing tissue for xenotransplantation in type I diabetic patients. We examined the functional and immunohistochemical outcome of the islet grafts in vitro during long-term culture and in vivo after transplantation to athymic nu...

journal_title：Cell transplantation

authors： Nielsen TB,Yderstraede KB,Schrøder HD,Holst JJ,Brusgaard K,Beck-Nielsen H

更新日期：2003-01-01 00:00:00

abstract：:This study was designed to investigate functional recovery after the transplantation of mesenchymal stem cells (MSCs) or neurally differentiated MSCs (NMSCs) derived from bone marrow in a rat model of spinal cord injury (SCI). Sprague-Dawley rats were subjected to incomplete SCI using an NYU impactor to create a free ...

journal_title：Cell transplantation

authors： Cho SR,Kim YR,Kang HS,Yim SH,Park CI,Min YH,Lee BH,Shin JC,Lim JB

更新日期：2016-07-01 00:00:00

abstract：:This invited concise review was written for the special issue of Cell Transplantation to celebrate the 25th anniversary of the American Society for Neural Therapy and Repair (ASNTR). I aimed to present a succinct summary of two interweaved lines of research work carried out by my team members and collaborators over th...

journal_title：Cell transplantation

authors： Teng YD

更新日期：2019-04-01 00:00:00

abstract：:Harvesting, expansion, and directed differentiation of human bone marrow-derived mesenchymal stem cells (BM-MSCs) could provide an autologous source of surrogate β-cells that would alleviate the limitations of availability and/or allogenic rejection following pancreatic or islet transplantation. Bone marrow cells were...

journal_title：Cell transplantation

authors： Gabr MM,Zakaria MM,Refaie AF,Ismail AM,Abou-El-Mahasen MA,Ashamallah SA,Khater SM,El-Halawani SM,Ibrahim RY,Uin GS,Kloc M,Calne RY,Ghoneim MA

更新日期：2013-01-01 00:00:00

abstract：:The clinical consequences of acute liver failure are associated with high mortality. Intensive medical intervention is required to treat the symptoms of liver failure, including coagulopathy, metabolic instability, and encephalopathy. Providing temporary liver support with an extracorporeal liver assist device could s...

journal_title：Cell transplantation

authors： Gregory PG,Connolly CK,Toner M,Sullivan SJ

更新日期：2000-01-01 00:00:00

abstract：:Procurement of multipotential neuroglial stem cells is possible with the addition of epidermal growth factor (EGF). Stem cells will differentiate into neurons and glia upon the removal of EGF from the culture medium. We have previously characterized the neuronal differentiation of stem cells derived from long-term cul...

journal_title：Cell transplantation

authors： Chiang YH,Silani V,Zhou FC

更新日期：1996-03-01 00:00:00

abstract：:We attempted to regenerate bone in a significant osseous defect with various stem cells from deciduous teeth, extracted from puppies, and grafted them into a parent canine mandible as an allograft, parent dental pulp, and bone marrow by tissue engineering and regenerative medicine technology using platelet-rich plasm...

journal_title：Cell transplantation

authors： Yamada Y,Ito K,Nakamura S,Ueda M,Nagasaka T

更新日期：2011-01-01 00:00:00

abstract：:The revascularization of islets of Langerhans transplanted in heterotopic sites like the liver by portal vein embolization or the renal subcapsular space is a major process necessary for the viability of grafted cells. This process has been extensively studied by different techniques and the results have shown that is...

journal_title：Cell transplantation

authors： Mendola JF,Conget I,Manzanares JM,Corominola H,Viñas O,Barcelo J,Gomis R

更新日期：1997-11-01 00:00:00

abstract：:Autologous cardiosphere-derived cells (CDCs) were the first therapeutic modality to demonstrate myocardial regeneration with a decrease in scar size and an increase in viable, functional tissue. Widespread applicability of autologous CDC therapy is limited by the need for patient-specific myocardial biopsy, cell proce...

journal_title：Cell transplantation

authors： Chakravarty T,Makkar RR,Ascheim DD,Traverse JH,Schatz R,DeMaria A,Francis GS,Povsic TJ,Smith RR,Lima JA,Pogoda JM,Marbán L,Henry TD

更新日期：2017-02-16 00:00:00

abstract：:Nerve growth factor (NGF) exerts both trophic (cell survival) and tropic (axonal growth-promoting) effects on several neuronal populations. In particular, its robust ability to prevent lesion-induced and spontaneous age-related basal forebrain cholinergic neuronal degeneration, and to promote mnemonic recovery, has su...

journal_title：Cell transplantation

authors： Tuszynski MH

更新日期：2000-09-01 00:00:00

abstract：:It is widely believed that human embryonic stem (huES) cells may represent a valid alternative to donor pancreata as a source of islets for transplantation. Much is known about the transcription factors whose sequential activation results in the generation of islets during pancreatic development. This knowledge has be...

journal_title：Cell transplantation

authors： Dominguez-Bendala J,Pastori RL,Ricordi C,Inverardi L

更新日期：2006-01-01 00:00:00

abstract：:Grafting autologous cultured satellite cells in irreversibly injured rat extensor digitorum longus EDL muscle leads to myofiber regeneration at the grafting site. In this study, we investigated whether cell grafts induced functional improvement and correlated mechanophysiological findings with histological observation...

journal_title：Cell transplantation

authors： Alameddine HS,Louboutin JP,Dehaupas M,Sébille A,Fardeau M

更新日期：1994-01-01 00:00:00

abstract：:An important challenge in pancreatic islet transplantation in association with type 1 diabetes is to define automatic high-throughput assays for evaluation of human islet function. The physiological techniques presently used are amenable to small-scale experimental samples and produce descriptive results. The postgeno...

journal_title：Cell transplantation

authors： Cabrera O,Jacques-Silva MC,Berman DM,Fachado A,Echeverri F,Poo R,Khan A,Kenyon NS,Ricordi C,Berggren PO,Caicedo A

更新日期：2008-01-01 00:00:00

abstract：:Human amniotic membrane (hAM) is the innermost layer of fetal membranes, which surrounds the developing fetus and forms the amniotic cavity. hAM and hAM-derived cells possess many properties that make them suitable for use in regenerative medicine, such as low immunogenicity, promotion of epithelization, anti-inflamma...

journal_title：Cell transplantation

authors： Ramuta TŽ,Kreft ME

更新日期：2018-01-01 00:00:00

abstract：:Apoptosis is a vital pathological factor that accounts for the poor prognosis of traumatic spinal cord injury (t-SCI). The 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is a critical regulator for energy metabolism and proven to have antiapoptotic effects. This study aimed to investigate the neuroprote...

journal_title：Cell transplantation

authors： Gao L,Wang C,Qin B,Li T,Xu W,Lenahan C,Ying G,Li J,Zhao T,Zhu Y,Chen G

更新日期：2020-01-01 00:00:00

abstract：:The present study aimed to elucidate the mechanisms by which hydrogen sulfide (H2S) attenuates left ventricular remodeling after myocardial infarction (MI). MI was created in mice by left coronary artery ligation. One group of mice received injections of the H2S donor sodium hydrosulfide (NaHS) immediately before and ...

journal_title：Cell transplantation

authors： Wu T,Li H,Wu B,Zhang L,Wu SW,Wang JN,Zhang YE

更新日期：2017-05-09 00:00:00

abstract：:Mouse embryonal carcinoma cell line P19 could be differentiated to neurons or glial cells by appropriate induction. We introduced the lacZ gene driven by a calmodulin promoter into P19 cells, and cloned the transfectant CaM-Z that showed the strong expression of lacZ gene after the induction of differentiation. CaM-Z ...

journal_title：Cell transplantation

authors： Watanabe R,Takase-Yoden S,Ikeda T,Atsumi T

更新日期：1996-09-01 00:00:00

abstract：:As a featured ocular inflammatory disease, autoimmune uveitis is the major cause of blindness in the clinic. Although current immunosuppressive regimens can alleviate the progression of autoimmune uveitis, they have serious side effects. Therefore, an alternative therapeutic strategy is urgently required. The present ...

journal_title：Cell transplantation

authors： Li J,Qiu C,Zhang Z,Yuan W,Ge Z,Tan B,Yang P,Liu J,Zhu X,Qiu C,Lai D,Guo L,Yu L

更新日期：2018-10-01 00:00:00