Percutaneous adventitial delivery of allogeneic bone marrow-derived stem cells via infarct-related artery improves long-term ventricular function in acute myocardial infarction.

abstract：:Sepsis is a life-threatening disease that results in excessive stimulation of the host's immune cells. In the animal study, the purpose was to investigate the roles of fresh frozen plasma (FFP) transfusion in shaping the CD4+ T lymphocytes immune response through modulating the secreted exosome protein Galectin-9 in m...

journal_title：Cell transplantation

authors： Zhang L,Zhang JP,Liu Y,Wang H,Cheng Y,Wang JH,Zhang WJ,Li ZZ,Guo JR

更新日期：2020-01-01 00:00:00

abstract：:At present, there are still significant barriers that impede the clinical use of hESCs and iPS cells, including ethics, immunorejection, tumorigenesis from hESCs, and teratoma formation from iPS cells. It is therefore necessary to search for alternative sources of stem cells. WJ-MSCs originate from embryonic epiblasts...

journal_title：Cell transplantation

authors： Gao LR,Zhang NK,Ding QA,Chen HY,Hu X,Jiang S,Li TC,Chen Y,Wang ZG,Ye Y,Zhu ZM

更新日期：2013-01-01 00:00:00

abstract：:The main purpose of this work has been to establish a new culturing technique to improve the chondrogenic commitment of isolated adult human chondrocytes, with the aim of being used during cell-based therapies or tissue engineering strategies. By using a rather novel technique to generate scaffold-free three-dimension...

journal_title：Cell transplantation

authors： Martinez I,Elvenes J,Olsen R,Bertheussen K,Johansen O

更新日期：2008-01-01 00:00:00

abstract：:There has been no gold standard for intraoperative monitoring in carotid endarterectomy (CEA) till now. The purpose of the current study was to investigate the value of near-infrared spectroscopy (NIRS) monitoring in CEA and explore the thresholds for intraoperative cerebral hypoperfusion. Eighty-four consecutive pati...

journal_title：Cell transplantation

authors： Wang Y,Li L,Wang T,Zhao L,Feng H,Wang Q,Fan L,Feng X,Xiao W,Feng K

更新日期：2019-02-01 00:00:00

abstract：:Although hepatic stem cells are believed to exist and play a critical role in developing and regenerating liver, little is known about their cell surface specificity or differentiation capabilities. To make prospective studies of hepatic stem cells possible, we established an in vitro culture system for identification...

journal_title：Cell transplantation

authors： Suzuki A,Zheng YW,Fukao K,Nakauchi H,Taniguchi H

更新日期：2001-01-01 00:00:00

abstract：:The major limitation of nonhuman primate (NHP) embryonic stem (ES) cell research is inefficient genetic modification and limited knowledge of differentiation mechanisms. A genetically modified NHP-ES cell with biomarkers, such as green fluorescent protein (GFP), that allow noninvasive monitoring of transgenic cells, i...

journal_title：Cell transplantation

authors： Takada T,Suzuki Y,Kondo Y,Kadota N,Kobayashi K,Nito S,Kimura H,Torii R

更新日期：2002-01-01 00:00:00

abstract：:A new extracorporeal bioartificial liver using alginate-entrapped hepatocytes was developed and evaluated for its ability to correct the lack of bilirubin conjugation in the Gunn rat. Hepatocytes were harvested from Sprague-Dawley rats by the two-step collagenase perfusion method and then immobilized in Ca(++)-alginat...

journal_title：Cell transplantation

authors： Fremond B,Malandain C,Guyomard C,Chesne C,Guillouzo A,Campion JP

更新日期：1993-11-01 00:00:00

abstract：:In Alzheimer's disease cholinergic neurons degenerate, resulting in loss of hippocampal acetylcholine. The fimbria-fornix aspiration is a well-known animal model mimicking hippocampal cholinergic deficiency. The aim of the present study was to use in vivo lipid-mediated gene transfer to introduce an expression vector ...

journal_title：Cell transplantation

authors： Weis C,Kaufmann WA,Humpel C

更新日期：2001-01-01 00:00:00

abstract：:Direct reprogramming of an adult cell into another differentiated lineage-such as fibroblasts into neurons, cardiomyocytes, or blood cells-without passage through an undifferentiated pluripotent stage is a new area of research that has recently emerged alongside stem cell technology and induced pluripotent stem cell r...

journal_title：Cell transplantation

authors： Nizzardo M,Simone C,Falcone M,Riboldi G,Comi GP,Bresolin N,Corti S

更新日期：2013-01-01 00:00:00

abstract：:Current good manufacturing practice (cGMP) islet processing facilities provide an ultraclean environment for the safe production of clinical grade islets for transplantation into immunosuppressed diabetic recipients. The objective of this study was to monitor the rate of microbial contamination in islet products after...

journal_title：Cell transplantation

authors： Kin T,Rosichuk S,Shapiro AM,Lakey JR

更新日期：2007-01-01 00:00:00

abstract：:One of the serious obstacles of the aortopathies research is a considerable shortage of human aortic smooth muscle cells (SMCs), which can be used to model the disease. SMC in most cases come from the whole aorta of transplant donors, which are rather difficult to access. In the course of coronary artery bypass graft ...

journal_title：Cell transplantation

authors： Kostina D,Zverev D,Grebennik V,Gordeev M,Ignatieva E,Voronkina I,Kostareva A,Malashicheva A

更新日期：2017-10-01 00:00:00

abstract：:Recently, animal studies have demonstrated the efficacy of endothelial progenitor cell (EPC) therapy for diabetic wound healing. Based on these preclinical studies, we performed a prospective clinical trial phase I/IIa study of autologous G-CSF-mobilized peripheral blood (PB) CD34(+) cell transplantation for nonhealin...

journal_title：Cell transplantation

authors： Tanaka R,Masuda H,Kato S,Imagawa K,Kanabuchi K,Nakashioya C,Yoshiba F,Fukui T,Ito R,Kobori M,Wada M,Asahara T,Miyasaka M

更新日期：2014-02-01 00:00:00

abstract：:Possible strategies for treating stroke include: 1) thrombolytic therapy with tissue plasminogen activator (tPA): restoring cerebral blood flow in the acute phase of ischemic stroke but sometimes causing hemorrhagic transformation (HT); 2) stem cell therapy: the repair of disrupted neuronal networks with newly born ne...

journal_title：Cell transplantation

authors： Yamashita T,Deguchi K,Nagotani S,Abe K

更新日期：2011-01-01 00:00:00

abstract：:For clinical islet transplantation, isolated islets deteriorate rapidly in culture, although culturing islets prior to transplantation provides flexibility for evaluation of isolated islets and pretreatment of patients. In the present study, we compared human fresh islets to cultured islets with in vitro and in vivo ...

journal_title：Cell transplantation

authors： Noguchi H,Naziruddin B,Jackson A,Shimoda M,Ikemoto T,Fujita Y,Chujo D,Takita M,Peng H,Sugimoto K,Itoh T,Kobayashi N,Onaca N,Levy MF,Matsumoto S

更新日期：2012-01-01 00:00:00

abstract：:Facioscapulohumeral muscular dystrophy (FSHD) is the third most frequent inherited myopathy. We previously demonstrated that mesoangioblasts can be efficiently isolated from FSHD muscles, although their differentiation ability into skeletal muscle was variably impaired. This correlates with overall disease severity a...

journal_title：Cell transplantation

authors： Morosetti R,Gidaro T,Broccolini A,Gliubizzi C,Sancricca C,Tonali PA,Ricci E,Mirabella M

更新日期：2011-01-01 00:00:00

abstract：:Hepatocyte transplantation is an alternative therapy to orthotopic liver transplantation for the treatment of liver diseases. However, the supply of hepatocytes is limited given the shortage of organs available to isolate good-functioning quality cells. Neonatal livers may be a potential source alternative to adult li...

journal_title：Cell transplantation

authors： Tolosa L,Pareja-Ibars E,Donato MT,Cortés M,López S,Jiménez N,Mir J,Castell JV,Gómez-Lechón MJ

更新日期：2014-01-01 00:00:00

abstract：:Neurodegenerative disorders, chronic diseases that can severely affect the patient's daily life, include amyotrophic lateral sclerosis, Parkinson's, Alzheimer's, and Huntington's diseases. However, these diseases all have the common characteristic that they are due to degenerative irreversibility, and thus no efficien...

journal_title：Cell transplantation

authors： Chan TM,Chen JY,Ho LI,Lin HP,Hsueh KW,Liu DD,Chen YH,Hsieh AC,Tsai NM,Hueng DY,Tsai ST,Chou PW,Lin SZ,Harn HJ

更新日期：2014-01-01 00:00:00

abstract：:Huntington's disease (HD) produces severe neurodegeneration in the striatum leading to disabling motor impairments, including the loss of control of skilled reaching movements. Fetal GABAergic transplants can physically replace the lost striatal cells but with only partial success in functional recovery. Here, we aime...

journal_title：Cell transplantation

authors： Klein A,Lane EL,Dunnett SB

更新日期：2013-01-01 00:00:00

abstract：:Addition of embryonic striatal tissue, usually as a combination of the lateral and medial ganglionic eminences, to intrastriatal mesencephalic grafts has previously been reported to enhance recovery of drug-induced rotational behavior in the host and to modify axonal fiber outgrowth from the grafted dopaminergic neuro...

journal_title：Cell transplantation

authors： Emgård-Mattson M,Karlsson J,Nakao N,Brundin P

更新日期：1997-05-01 00:00:00

abstract：:In multiple sclerosis (MS), a chronic inflammatory relapsing demyelinating disease, failure to control or repair damage leads to progressive neurological dysfunction and neurodegeneration. Implantation of neural stem cells (NSCs) has been shown to promote repair and functional recovery in the acute experimental autoi...

journal_title：Cell transplantation

authors： Sher F,Amor S,Gerritsen W,Baker D,Jackson SL,Boddeke E,Copray S

更新日期：2012-01-01 00:00:00

abstract：:The biohybrid artificial pancreas is designed to enclose pancreatic tissues with a selectively permeable membrane that immunoisolates the graft from the host immune system, allowing those endocrine tissues to survive and control glucose metabolism for an extended period of time. The pancreatic B cell line MIN6 is esta...

journal_title：Cell transplantation

authors： Kawakami Y,Inoue K,Hayashi H,Wang WJ,Setoyama H,Gu YJ,Imamura M,Iwata H,Ikada Y,Nozawa M,Miyazaki J

更新日期：1997-09-01 00:00:00

abstract：:The periodontal ligament displays a reservoir of mesenchymal stem cells which can account for periodontal regeneration. Despite the numerous studies directed at the definition of optimal culture conditions for long-term expansion of periodontal ligament stem cells (PDLSCs), no consensus has been reached as to what is ...

journal_title：Cell transplantation

authors： Di Vito A,Giudice A,Chiarella E,Malara N,Bennardo F,Fortunato L

更新日期：2019-01-01 00:00:00

abstract：:Cellular transplantation strategies utilizing intraspinal or intrathecal olfactory ensheathing cells (OECs) have been reported as beneficial for spinal cord injury (SCI). However, there are many disadvantages of these methods, including additional trauma to the spinal cord parenchyma and technical challenges. Therefor...

journal_title：Cell transplantation

authors： Zhang L,Zhuang X,Chen Y,Xia H

更新日期：2019-12-01 00:00:00

abstract：:Heart failure continues to be a major health care concern with relatively few options for severely advanced heart failure patients. The hallmark of heart failure is the progressive dilatation of the left ventricle, thinning of the left ventricular wall leading to increased wall stress and increased myocardial oxygen c...

journal_title：Cell transplantation

authors： Lee RJ,Hinson A,Helgerson S,Bauernschmitt R,Sabbah HN

更新日期：2013-01-01 00:00:00

abstract：:Periosteal autografts have the potential to regenerate articular cartilage defects, but this potential is limited by the patient's age. Allograft transplantation from a young donor to an older recipient might bypass this limitation. The effect of the time delay, between death and harvesting of a periosteal graft, on t...

journal_title：Cell transplantation

authors： O'Driscoll SW,Meisami B,Miura Y,Fitzsimmons JS

更新日期：1999-11-01 00:00:00

abstract：:The recent advent of endoscopy has enabled the endoscopic submucosal dissection (ESD) of superficial nonampullary duodenal epithelial tumors. However, the substantially thin wall and presence of bile and pancreatic juice make it technically difficult to perform duodenal ESD without perforation, which leads to lethal c...

journal_title：Cell transplantation

authors： Matsumoto R,Kanetaka K,Maruya Y,Yamaguchi S,Kobayashi S,Miyamoto D,Ohnita K,Sakai Y,Hashiguchi K,Nakao K,Eguchi S

更新日期：2020-01-01 00:00:00

abstract：:Cardiovascular disease is a major cause of morbidity, disability, and mortality in kidney transplant patients. Cumulative reports indicate that the excessive risk of cardiovascular events is not entirely explained by the increased prevalence of traditional cardiovascular risk factors. Atherosclerosis is a chronic infl...

journal_title：Cell transplantation

authors： Ducloux D,Bamoulid J,Crepin T,Rebibou JM,Courivaud C,Saas P

更新日期：2017-09-01 00:00:00

abstract：:Schwann cells naturally support axonal regeneration after injury in the peripheral nervous system, and have also shown a significant, albeit limited, ability to support axonal growth and remyelination after grafting to the central nervous system (CNS). It is possible that Schwann cell-induced axonal growth in the CNS ...

journal_title：Cell transplantation

authors： Tuszynski MH,Weidner N,McCormack M,Miller I,Powell H,Conner J

更新日期：1998-03-01 00:00:00

abstract：:Airway epithelial cell injury is a key triggering event to activate allergic airway inflammation, such as asthma. We previously reported that administration of mesenchymal stem cells (MSCs) significantly alleviated allergic inflammation in a mouse model of asthma, and the mmu-miR-21/ACVR2A axis may be involved. Howeve...

journal_title：Cell transplantation

authors： Li CL,Xu ZB,Fan XL,Chen HX,Yu QN,Fang SB,Wang SY,Lin YD,Fu QL

更新日期：2018-03-01 00:00:00

abstract：:The anatomical specificity of axon growth from fetal pig septal xenografts was studied by transplanting septal cells from E30-35 pig fetuses into cholinergic deafferented (192-IgG-saporin-infused) rats or into aged rats (> 18 months). Cell suspensions (100,000 cells/microl) were injected bilaterally into the dorsal an...

journal_title：Cell transplantation

authors： Deacon T,Whatley B,LeBlanc C,Lin L,Isacson O

更新日期：1999-01-01 00:00:00