Aortic Graft at Coronary Artery Bypass Surgery as a Source of Human Aortic Smooth Muscle Cells.

abstract：:Neuroblastoma, a malignant tumor of the sympathetic nervous system, is an aggressive extracranial tumor in childhood. Long noncoding RNAs (lncRNAs) have been discovered to play a key role in the eukaryotic regulatory gene network and be involved in a wide variety of biological processes. We observed that the expressio...

journal_title：Cell transplantation

authors： Pan W,Wu A,Yu H,Yu Q,Zheng B,Yang W,Tian D,Gao Y,Li P

更新日期：2020-01-01 00:00:00

abstract：:There is conflicting evidence favoring both the use of human serum (HS) and of human serum albumin (HSA) in human islet culture. We evaluated the effects of HS versus HSA supplementation on 1) in vitro β-cell viability and function and 2) in vivo islet graft revascularization, islet viability, β-cell death, and metabo...

journal_title：Cell transplantation

authors： Nacher M,Estil Les E,Garcia A,Nadal B,Pairó M,Garcia C,Secanella L,Novials A,Montanya E

更新日期：2016-01-01 00:00:00

abstract：:Regenerative medicine aims to repair and regenerate damaged cells, tissues, and organs in order to restore function. Regeneration can be obtained either by cell replacement or by stimulating the body's own repair mechanisms. Importantly, a favorable environment is required before any regenerative signal can stimulate ...

journal_title：Cell transplantation

authors： Silini AR,Magatti M,Cargnoni A,Parolini O

更新日期：2017-04-13 00:00:00

abstract：:Current good manufacturing practice (cGMP) islet processing facilities provide an ultraclean environment for the safe production of clinical grade islets for transplantation into immunosuppressed diabetic recipients. The objective of this study was to monitor the rate of microbial contamination in islet products after...

journal_title：Cell transplantation

authors： Kin T,Rosichuk S,Shapiro AM,Lakey JR

更新日期：2007-01-01 00:00:00

abstract：:Multiple sclerosis is a disease characterized by inflammation and demyelination located in the central nervous system. Experimental autoimmune encephalomyelitis (EAE) is the most common animal model for multiple sclerosis (MS). Although the roles of T cells in MS/EAE have been well investigated, little is known about ...

journal_title：Cell transplantation

authors： Xu J,Wang Y,Jiang H,Sun M,Gao J,Xie A

更新日期：2019-09-01 00:00:00

abstract：:Acute kidney injury (AKI) is a major clinical problem that still has no established treatment. We investigated the efficacy of cultured human peripheral blood mononuclear cells (PBMNCs) for AKI. Ischemia/reperfusion injury (IRI) was used to induce AKI in male nonobese diabetic (NOD/severe combined immunodeficiency) mi...

journal_title：Cell transplantation

authors： Ohtake T,Kobayashi S,Slavin S,Mochida Y,Ishioka K,Moriya H,Hidaka S,Matsuura R,Sumida M,Katagiri D,Noiri E,Okada K,Mizuno H,Tanaka R

更新日期：2018-03-01 00:00:00

abstract：:Exenatide is an analog of the incretin hormone glucagon-like peptide (GLP-1) that is used for the treatment of T2D for their metabolic effects. In addition to its insulinotropic effects, exenatide increases functional islet mass and improves their survival. Improved outcomes have been reported in recent clinical isle...

journal_title：Cell transplantation

authors： Cechin SR,Pérez-Álvarez I,Fenjves E,Molano RD,Pileggi A,Berggren PO,Ricordi C,Pastori RL

更新日期：2012-01-01 00:00:00

abstract：:Prognosis of patients with heart failure remains poor despite improved conventional and interventional treatment regimens. The improvement of neovascularization and repair processes by administration of bone marrow-derived cells modestly improved the recovery after acute myocardial infarction. However, circulating pat...

journal_title：Cell transplantation

authors： Honold J,Fischer-Rasokat U,Lehmann R,Leistner DM,Seeger FH,Schachinger V,Martin H,Dimmeler S,Zeiher AM,Assmus B

更新日期：2012-01-01 00:00:00

abstract：:Stem cells from dental tissues have been isolated and established for tooth regenerative applications. However, basic characterization on their biological properties still needs to be investigated before employing them for effective clinical trials. In this study, we compared the telomere length, relative telomerase ...

journal_title：Cell transplantation

authors： Jeon BG,Kang EJ,Kumar BM,Maeng GH,Ock SA,Kwack DO,Park BW,Rho GJ

更新日期：2011-01-01 00:00:00

abstract：:In multiple sclerosis (MS), a chronic inflammatory relapsing demyelinating disease, failure to control or repair damage leads to progressive neurological dysfunction and neurodegeneration. Implantation of neural stem cells (NSCs) has been shown to promote repair and functional recovery in the acute experimental autoi...

journal_title：Cell transplantation

authors： Sher F,Amor S,Gerritsen W,Baker D,Jackson SL,Boddeke E,Copray S

更新日期：2012-01-01 00:00:00

abstract：:Clinically, many candidates for islet transplantation are already immunized, which increases their risk of graft rejection. Encapsulation of pancreatic islets using the TheraCyte™ device has been shown to protect against allograft rejection in nonimmunized recipients. However, the capacity of the TheraCyte™ device to ...

journal_title：Cell transplantation

authors： Kumagai-Braesch M,Jacobson S,Mori H,Jia X,Takahashi T,Wernerson A,Flodström-Tullberg M,Tibell A

更新日期：2013-01-01 00:00:00

abstract：:An in vivo tracer technique that uses radiolabeled insulin as the tracer molecule has been developed to assess the rate of chemical transport between the cell transplantation chamber of an implantable bioartificial device and the host's circulatory system. The device considered here employs site-directed neovasculariz...

journal_title：Cell transplantation

authors： Sarver JG,Fournier RL,Goldblatt PJ,Phares TL,Mertz SE,Baker AR,Mellon RJ,Horner JM,Selman SH

更新日期：1995-03-01 00:00:00

abstract：:ET-Kyoto solution (ET-K) is an extracellular-type organ preservation solution containing the cytoprotective disaccharide, trehalose. A previous study reported the supplement of dibutyryl cyclic adenosine monophosphate (db-cAMP) in conventional ET-K to attenuate lung ischemia-reperfusion injury. In this study, the effi...

journal_title：Cell transplantation

authors： Zhao X,Koshiba T,Nakamura T,Tsuruyama T,Li Y,Bando T,Wada H,Tanaka K

更新日期：2008-01-01 00:00:00

abstract：:Autism spectrum disorders (ASDs) are heterogeneous complex neurodevelopmental pathologies defined by behavioral symptoms, but which have well-characterized genetic, immunological, and physiological comorbidities. Despite extensive research efforts, there are presently no agreed upon therapeutic approaches for either t...

journal_title：Cell transplantation

authors： Bradstreet JJ,Sych N,Antonucci N,Klunnik M,Ivankova O,Matyashchuk I,Demchuk M,Siniscalco D

更新日期：2014-01-01 00:00:00

abstract：:Cloned murine endothelial cells (cEC) were used as a carrier system for introducing a foreign gene into the microvascular bed of the hind limb of inbred mice. cEC were transfected with a beta-galactosidase-neo fusion construct, which enables both selection for DNA uptake in the presence of G 418 and the staining of ce...

journal_title：Cell transplantation

authors： Schwärzler C,Webersinke G,Fässler R,Lametschwandtner A,Bauer H,Bauer HC

更新日期：1997-01-01 00:00:00

abstract：:The biohybrid artificial pancreas is designed to enclose pancreatic tissues with a selectively permeable membrane that immunoisolates the graft from the host immune system, allowing those endocrine tissues to survive and control glucose metabolism for an extended period of time. The pancreatic B cell line MIN6 is esta...

journal_title：Cell transplantation

authors： Kawakami Y,Inoue K,Hayashi H,Wang WJ,Setoyama H,Gu YJ,Imamura M,Iwata H,Ikada Y,Nozawa M,Miyazaki J

更新日期：1997-09-01 00:00:00

abstract：:Since donor T-cells' allorecognition of host antigens is a prerequisite for the onset of graft-versus-host disease (GVHD), blocking their cellular signaling pathways can decrease the severity of GVHD. We hypothesized that epigallocatechin-3-gallate (EGCG), due to its strong affinity to macromolecules, would adhere to...

journal_title：Cell transplantation

authors： Kanamune J,Iwanaga Y,Kina T,Noguchi H,Matsumura K,Uemoto S,Hyon SH

更新日期：2012-01-01 00:00:00

abstract：:Bisphosphonates (BPs) are widely used to treat several metabolic and oncological diseases affecting the skeletal system. Despite BPs' well-known therapeutic potential, they also displayed important side effects, among which is BPs-related osteonecrosis of the jaw, by targeting osteoclast activities, osteoblast, and os...

journal_title：Cell transplantation

authors： Di Vito A,Chiarella E,Baudi F,Scardamaglia P,Antonelli A,Giudice D,Barni T,Fortunato L,Giudice A

更新日期：2020-01-01 00:00:00

abstract：:Techniques for medical tissue regeneration require an abundant source of human adult stem cells. There is increasing evidence that adipose stem cells contribute to restoration of tissue vascularization and organ function. The object of our study was to isolate and characterize adult adipose-derived stem cells from pat...

journal_title：Cell transplantation

authors： Folgiero V,Migliano E,Tedesco M,Iacovelli S,Bon G,Torre ML,Sacchi A,Marazzi M,Bucher S,Falcioni R

更新日期：2010-01-01 00:00:00

abstract：:The major limitation of nonhuman primate (NHP) embryonic stem (ES) cell research is inefficient genetic modification and limited knowledge of differentiation mechanisms. A genetically modified NHP-ES cell with biomarkers, such as green fluorescent protein (GFP), that allow noninvasive monitoring of transgenic cells, i...

journal_title：Cell transplantation

authors： Takada T,Suzuki Y,Kondo Y,Kadota N,Kobayashi K,Nito S,Kimura H,Torii R

更新日期：2002-01-01 00:00:00

abstract：:Transplanted embryonic stem (ES) cells, following myocardial infarction (MI), contribute to limited cardiac repair and regeneration with improved function. Therefore, novel strategies are still needed to understand the effects of genetically modified transplanted stem cells on cardiac remodeling. The present study ev...

journal_title：Cell transplantation

authors： Glass C,Singla DK

更新日期：2012-01-01 00:00:00

abstract：:Several molecular therapies require the implantation of cells that secrete biotherapeutic molecules and imaging the location and microenvironment of the cellular implant to ascertain its function. We demonstrate noninvasive in vivo magnetic resonance imaging (MRI) of self-assembled microcontainers that are capable of ...

journal_title：Cell transplantation

authors： Gimi B,Artemov D,Leong T,Gracias DH,Gilson W,Stuber M,Bhujwalla ZM

更新日期：2007-01-01 00:00:00

abstract：:This invited concise review was written for the special issue of Cell Transplantation to celebrate the 25th anniversary of the American Society for Neural Therapy and Repair (ASNTR). I aimed to present a succinct summary of two interweaved lines of research work carried out by my team members and collaborators over th...

journal_title：Cell transplantation

authors： Teng YD

更新日期：2019-04-01 00:00:00

abstract：:Previous observations in heat-shocked pig islets revealed the ambivalent character of the stress response simultaneously inducing processes of protection and apoptosis. To clarify whether the proapoptotic character of the stress response is reduced in heat-exposed islets still embedded in their native environment, hyp...

journal_title：Cell transplantation

authors： Brandhorst H,Olbrich M,Neumann A,Jahr H,Brandhorst D

更新日期：2007-01-01 00:00:00

abstract：REGISTRATION NUMBER OF CLINICAL TRIALS:ChiCTR1900021317. ...

journal_title：Cell transplantation

authors： He M,Guo X,Li T,Jiang X,Chen Y,Yuan Y,Chen B,Yang G,Fan Y,Liang Z,Armstrong DG,Deng W

更新日期：2020-01-01 00:00:00

abstract：:Cardiovascular disease is a major cause of morbidity, disability, and mortality in kidney transplant patients. Cumulative reports indicate that the excessive risk of cardiovascular events is not entirely explained by the increased prevalence of traditional cardiovascular risk factors. Atherosclerosis is a chronic infl...

journal_title：Cell transplantation

authors： Ducloux D,Bamoulid J,Crepin T,Rebibou JM,Courivaud C,Saas P

更新日期：2017-09-01 00:00:00

abstract：:Cell escape occurs after intramyocardial injection for treatment of myocardial infarction (MI) and then the migrated cells might be entrapped by extracardiac organs. We investigated the fate of migrated bone marrow-derived mesenchymal stromal cells (MSCs) and their impact on lung, liver, and spleen. MI model was creat...

journal_title：Cell transplantation

authors： Wang W,Jin P,Wang L,Yang Z,Hu S,Gao B,Zhang H

更新日期：2010-01-01 00:00:00

abstract：:The human neuronal cell-1 (HCN-1) line has recently been established. Under favorable conditions, these cells differentiate into mature neuronal phenotypes. Here we report on further characterization of these cells. Cultured HCN-1 cells express fibronectin immunoreactivity and grow well on fibronectin substrate but do...

journal_title：Cell transplantation

authors： Poltorak M,Isono M,Freed WJ,Ronnett GV,Snyder SH

更新日期：1992-01-01 00:00:00

abstract：:Airway epithelial cell injury is a key triggering event to activate allergic airway inflammation, such as asthma. We previously reported that administration of mesenchymal stem cells (MSCs) significantly alleviated allergic inflammation in a mouse model of asthma, and the mmu-miR-21/ACVR2A axis may be involved. Howeve...

journal_title：Cell transplantation

authors： Li CL,Xu ZB,Fan XL,Chen HX,Yu QN,Fang SB,Wang SY,Lin YD,Fu QL

更新日期：2018-03-01 00:00:00

abstract：:Experiments on spinal cord injury (SCI) have largely focused on the transplantation of stem cells into injured spinal cords for motor recovery while neglecting to investigate bladder dysfunction. The present study was performed to investigate the effect of B10 human mesenchymal stem cells (hMSCs) directly transplanted...

journal_title：Cell transplantation

authors： Lee HJ,An J,Doo SW,Kim JH,Choi SS,Lee SR,Park SW,Song YS,Kim SU

更新日期：2015-01-01 00:00:00