Incorporation of beta-galactosidase-expressing endothelial cells into the skeletal muscle microvascular bed of mice.

abstract：:The integrity of the blood-brain barrier (BBB) plays a vital role in affecting the prognosis of subarachnoid hemorrhage (SAH). This study aimed to investigate activation of the Tropomyosin-related kinase receptor B (TrkB) and its downstream signaling pathway on preserving BBB breakdown after experimental SAH. An endov...

journal_title：Cell transplantation

authors： Qi X,Liu J,Wu J,Bi Y,Han C,Zhang G,Lou M,Lu J,Tang J

更新日期：2019-08-01 00:00:00

abstract：:The biohybrid artificial pancreas is designed to enclose pancreatic tissues with a selectively permeable membrane that immunoisolates the graft from the host immune system, allowing those endocrine tissues to survive and control glucose metabolism for an extended period of time. The pancreatic B cell line MIN6 is esta...

journal_title：Cell transplantation

authors： Kawakami Y,Inoue K,Hayashi H,Wang WJ,Setoyama H,Gu YJ,Imamura M,Iwata H,Ikada Y,Nozawa M,Miyazaki J

更新日期：1997-09-01 00:00:00

abstract：:Simple and efficient freezing methods with maximal postthawing recovery form the basis of ideal cryopreservation. Taurine (2-amino ethanesulfonic acid), an end-product of sulphur amino acid metabolism, is one of the most abundant free amino acids in the body. The membrane stabilizing, free radical scavenging, and osmo...

journal_title：Cell transplantation

authors： Hardikar AA,Risbud MV,Remacle C,Reusens B,Hoet JJ,Bhonde RR

更新日期：2001-01-01 00:00:00

abstract：:Cerebral palsy (CP) is a common disability which results in permanent chronic motor disability appearing in early childhood. Recently human umbilical cord blood mesenchymal stem cell (hUCB-MSC) infusion has emerged as a promising therapeutic strategy for CP, and the treatment efficacy remains to be confirmed by clinic...

journal_title：Cell transplantation

authors： Huang L,Zhang C,Gu J,Wu W,Shen Z,Zhou X,Lu H

更新日期：2018-02-01 00:00:00

abstract：:"Proof-of-principle" that cell replacement therapy works for neurodegeneration has been reported, but only using donor cells collected from fetal brain tissue obtained from surgical terminations of pregnancy. Surgical terminations of pregnancy represent an increasingly limited supply of donor cells due to the tendenc...

journal_title：Cell transplantation

authors： Kelly CM,Precious SV,Torres EM,Harrison AW,Williams D,Scherf C,Weyrauch UM,Lane EL,Allen ND,Penketh R,Amso NN,Kemp PJ,Dunnett SB,Rosser AE

更新日期：2011-01-01 00:00:00

abstract：:Hematopoietic stem and progenitor cells reside within the bone marrow (BM) microenvironment. By a well-balanced interplay between self-renewal and differentiation, they ensure a lifelong supply of mature blood cells. Physiologically, multiple different cell types contribute to the regulation of stem and progenitor cel...

journal_title：Cell transplantation

authors： Mattiucci D,Maurizi G,Leoni P,Poloni A

更新日期：2018-05-01 00:00:00

abstract：:Direct reprogramming of an adult cell into another differentiated lineage-such as fibroblasts into neurons, cardiomyocytes, or blood cells-without passage through an undifferentiated pluripotent stage is a new area of research that has recently emerged alongside stem cell technology and induced pluripotent stem cell r...

journal_title：Cell transplantation

authors： Nizzardo M,Simone C,Falcone M,Riboldi G,Comi GP,Bresolin N,Corti S

更新日期：2013-01-01 00:00:00

abstract：:Achieving good islet isolation is one of the most important factors for successful islet transplantation. Porcine pancreas is suitable for islet isolation research due to its anatomical and physiological similarities to human pancreas. In this study, we evaluated a new porcine islet isolation method designed to maximi...

journal_title：Cell transplantation

authors： Yonekawa Y,Matsumoto S,Okitsu T,Arata T,Iwanaga Y,Noguchi H,Nagata H,O'Neil JJ,Tanaka K

更新日期：2005-01-01 00:00:00

abstract：:The transplantation of encapsulated dopamine-secreting cells into the striatum represents one potential means of treating Parkinson's disease. The present study investigated the ability of encapsulated PC12 cells, which are derived from rat pheochromocytoma, to supply L-dopa and dopamine into the primate brain in the ...

journal_title：Cell transplantation

authors： Date I,Shingo T,Yoshida H,Fujiwara K,Kobayashi K,Ohmoto T

更新日期：2000-09-01 00:00:00

abstract：:Transplantation of human cells after isolation and culture has become an important alternative for treatment of acute or chronic skin wounds. To increase the efficacy and reduce cost for transplantation of skin cells, more efficient and accurate techniques for evaluation of cell proliferation are needed. Hemocytometer...

journal_title：Cell transplantation

authors： Boyce ST,Anderson BA,Rodriguez-Rilo HL

更新日期：2006-01-01 00:00:00

abstract：:Major skin burns are difficult to treat. Patients often require special care and long-term hospitalization. Besides specific complications associated with the wounds themselves, there may be impairment of the immune system and of other organs. Mesenchymal stromal cells (MSCs) are a recent therapeutic alternative to tr...

journal_title：Cell transplantation

authors： Caliari-Oliveira C,Yaochite JN,Ramalho LN,Palma PV,Carlos D,Cunha Fde Q,De Souza DA,Frade MA,Covas DT,Malmegrim KC,Oliveira MC,Voltarelli JC

更新日期：2016-01-01 00:00:00

abstract：:Previously, we found that hepatocyte growth factor receptor (c-Met)-and alpha-fetoprotein (AFP)-expressing cells were present in adult rat bone marrow, and that these cells also expressed hematopoietic stem cell markers, such as CD34, Thy-1, and c-Kit. When bone marrow cells were cultured in a hepatocyte growth medium...

journal_title：Cell transplantation

authors： Miyazaki M,Masaka T,Akiyama I,Nakashima E,Sakaguchi M,Huh NH

更新日期：2004-01-01 00:00:00

abstract：:We examined whether hypoxic exposure prior to the event of transplantation would have a positive or negative effect upon later islet graft function. Mouse islets exposed to hypoxic culture were transplanted into syngeneic recipients. Islet graft function, β-cell physiology, as well as molecular changes were examined. ...

journal_title：Cell transplantation

authors： Cantley J,Walters SN,Jung MH,Weinberg A,Cowley MJ,Whitworth TP,Kaplan W,Hawthorne WJ,O'Connell PJ,Weir G,Grey ST

更新日期：2013-01-01 00:00:00

abstract：:The formation of a new microvasculature is essential for the long-term survival and function of the islet graft. In this study we examined endothelium of isolated pancreatic islets by stimulation with growth factors, different culture conditions, and genetic modification. We also inspected the effect of immunosuppress...

journal_title：Cell transplantation

authors： Kidszun A,Schneider D,Erb D,Hertl G,Schmidt V,Eckhard M,Preissner KT,Breier G,Bretzel RG,Linn T

更新日期：2006-01-01 00:00:00

abstract：:The ability to replace damaged myocardial tissue with new striated muscle would constitute a major advance in the treatment of diseases that irreversibly injure cardiac muscle cells. The creation of focal grafts of skeletal muscle has been reported following the intramural injection of skeletal myoblasts into both nor...

journal_title：Cell transplantation

authors： Robinson SW,Cho PW,Levitsky HI,Olson JL,Hruban RH,Acker MA,Kessler PD

更新日期：1996-01-01 00:00:00

abstract：:Transplantation therapies aimed at repairing neurodegenerative and neuropathological conditions of the central nervous system (CNS) have utilized and tested a variety of cell candidates, each with its own unique set of advantages and disadvantages. The use and popularity of each cell type is guided by a number of fact...

journal_title：Cell transplantation

authors： Kramer AS,Harvey AR,Plant GW,Hodgetts SI

更新日期：2013-01-01 00:00:00

abstract：:Membrane integrity fluorescent staining is used routinely to evaluate islet viability. Results are used as one of the determining factors in islet product release criteria, and are used to assess the efficacy of different culture conditions. Recently, it has been observed that there is variation in the viability stain...

journal_title：Cell transplantation

authors： Barnett MJ,McGhee-Wilson D,Shapiro AM,Lakey JR

更新日期：2004-01-01 00:00:00

abstract：:Cell replacement therapy by intracerebral transplantation of fetal dopaminergic neurons has become a promising therapeutic option for patients suffering from Parkinson's disease during the last decades. However, limited availability of human fetal tissue as well as ethical issues, lack of alternative nonfetal donor ce...

journal_title：Cell transplantation

authors： Rath A,Klein A,Papazoglou A,Pruszak J,Garcia J,Krause M,Maciaczyk J,Dunnett SB,Nikkhah G

更新日期：2013-01-01 00:00:00

abstract：:Ten mongrel dogs were used in this study. Diabetes was chemically induced in 7 dogs, and 3 dogs served as normal controls. For each diabetic dog, 5 million human bone marrow-derived mesenchymal stem cells/kg were differentiated to form insulin-producing cells using a trichostatin-based protocol. Cells were then loaded...

journal_title：Cell transplantation

authors： Gabr MM,Zakaria MM,Refaie AF,Ismail AM,Khater SM,Ashamallah SA,Azzam MM,Ghoneim MA

更新日期：2018-06-01 00:00:00

abstract：:Mononuclear stem cells have been studied for their potential in myocardial ischemia. In our previous published article, ReACT(®) phase I/II clinical trial, our results suggest that a certain cell population, promonocytes, directly correlated with the perceived angiogenesis in refractory angina patients. This study is ...

journal_title：Cell transplantation

authors： Hossne NA,Cruz E,Buffolo E,Coimbra AC,Machado J,Goldenberg RC,Regazzi G,Azevedo S,Invitti AL,Rodrigues Branco JN,Rodrigues de Oliveira JS,Stolf NA,Miller LW,Sanberg PR

更新日期：2015-01-01 00:00:00

abstract：:Cotransplantation of neural progenitors (NPs) with Schwann cells (SCs) might be a way to overcome low rate of neuronal differentiation of NPs following transplantation in spinal cord injury (SCI) and the improvement of locomotor recovery. In this study, we initially generated NPs from human embryonic stem cells (hESC...

journal_title：Cell transplantation

authors： Niapour A,Karamali F,Nemati S,Taghipour Z,Mardani M,Nasr-Esfahani MH,Baharvand H

更新日期：2012-01-01 00:00:00

abstract：:Stem cell transplants into damaged myocardium may have the potential to improve cardiac function. We investigated the safety of transplanting unmanipulated autologous bone marrow into infarcted myocardium of patients undergoing coronary bypass surgery and assessed its efficacy to improve cardiac function. Fourteen pat...

journal_title：Cell transplantation

authors： Galiñanes M,Loubani M,Davies J,Chin D,Pasi J,Bell PR

更新日期：2004-01-01 00:00:00

abstract：:Neural progenitor cells (NPCs) overexpressing fibroblast growth factor 2 (FGF-2) have the distinct tendency to associate with the vasculature and establish multiple proliferative clusters in the perivascular environment after transplantation into the cerebral cortex. Strikingly, the vascular clusters of progenitor cel...

journal_title：Cell transplantation

authors： Tsupykov O,Kanemitsu M,Smozhanik E,Skibo G,Dayer AG,Kiss JZ

更新日期：2016-01-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) displays high resistance to radiation and chemotherapy, due to the presence of a fraction of GBM stem-like cells (GSLCs), which are thus representing the target for GBM elimination. Since mesenchymal stem cells (MSCs) display high tumor tropism, we examined possible antitumor effects of t...

journal_title：Cell transplantation

authors： Kološa K,Motaln H,Herold-Mende C,Koršič M,Lah TT

更新日期：2015-01-01 00:00:00

abstract：:Cardiac cell therapy with mesenchymal stem cells (MSCs) represents a promising treatment approach for end-stage heart failure. However, little is known about the underlying mechanisms and the fate of the transplanted cells. The objective of the presented work is to determine the feasibility of magnetic resonance imagi...

journal_title：Cell transplantation

authors： Drey F,Choi YH,Neef K,Ewert B,Tenbrock A,Treskes P,Bovenschulte H,Liakopoulos OJ,Brenkmann M,Stamm C,Wittwer T,Wahlers T

更新日期：2013-01-01 00:00:00

abstract：:Pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, have generated much excitement about their prospects for use in cell transplantation therapies. This is largely attributable to their virtually unlimited growth potential, their ability to be precisely genetically altered ...

journal_title：Cell transplantation

authors： Robinson AJ,Zhao G,Rathjen J,Rathjen PD,Hutchinson RG,Eyre HJ,Hemsley KM,Hopwood JJ

更新日期：2010-01-01 00:00:00

abstract：:Pancreas procurement for islet isolation and transplantation is limited by concerns for the detrimental effects of postmortem ischemia. Hypothermic machine perfusion (HMP) preservation technology has had a major impact in circumventing ischemic injury in clinical kidney transplantation and is applied here to the prese...

journal_title：Cell transplantation

authors： Taylor MJ,Baicu S,Greene E,Vazquez A,Brassil J

更新日期：2010-01-01 00:00:00

abstract：:Periosteal autografts have the potential to regenerate articular cartilage defects, but this potential is limited by the patient's age. Allograft transplantation from a young donor to an older recipient might bypass this limitation. The effect of the time delay, between death and harvesting of a periosteal graft, on t...

journal_title：Cell transplantation

authors： O'Driscoll SW,Meisami B,Miura Y,Fitzsimmons JS

更新日期：1999-11-01 00:00:00

abstract：:Regenerative medicine aims to repair and regenerate damaged cells, tissues, and organs in order to restore function. Regeneration can be obtained either by cell replacement or by stimulating the body's own repair mechanisms. Importantly, a favorable environment is required before any regenerative signal can stimulate ...

journal_title：Cell transplantation

authors： Silini AR,Magatti M,Cargnoni A,Parolini O

更新日期：2017-04-13 00:00:00

abstract：:Current good manufacturing practice (cGMP) islet processing facilities provide an ultraclean environment for the safe production of clinical grade islets for transplantation into immunosuppressed diabetic recipients. The objective of this study was to monitor the rate of microbial contamination in islet products after...

journal_title：Cell transplantation

authors： Kin T,Rosichuk S,Shapiro AM,Lakey JR

更新日期：2007-01-01 00:00:00