Abstract:
:Six naturally occurring C27 ecdysteroids were isolated and identified from the tobacco hornworm during pupal-adult development five days after peak titer of molting hormone activity. In order of decreasing quantities the hormones were: 20,26-dihydroxyecdysone, 3-epi-20-hydroxyecdysone, 20hydroxyecdysone, 3-epi-20,26-dihydroxyecdysone, 3-epi-ecdysone, and ecdysone. 20-Hydroxyecdysone, in an earlier study, was the major molting hormone present at peak titer during pupal-adult development. The major ecdysteroid present during embryonic development in this insect, 26-hydroxyecdysone, was not detected. The copresence of all six of these ecdysteroids from a single developmental stage of an insect provides information on the metabolic interrelationships that exist among these steroids and on their possible function(s) in insects. The 3alpha-ecdysteroids were far less active than the 3 beta-epimers in the house fly assay. The significance of epimerization is discussed.
journal_name
Steroidsjournal_title
Steroidsauthors
Kaplanis JN,Thompson MJ,Dutky SR,Robbins WEdoi
10.1016/0039-128x(79)90084-9subject
Has Abstractpub_date
1979-09-01 00:00:00pages
333-45issue
3eissn
0039-128Xissn
1878-5867pii
0039-128X(79)90084-9journal_volume
34pub_type
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