The possible role of the novel cytokines il-35 and il-37 in inflammatory bowel disease.

abstract：:Peripheral artery disease (PAD) is a common disease affecting 20-25% of population over 60 years old. Early diagnosis is difficult because symptoms only become evident in advanced stages of the disease. Inflammation, impaired metabolism, and mitochondrial dysfunction predispose to PAD, which is normally associated wit...

journal_title：Mediators of inflammation

authors： Hernández-Aguilera A,Fernández-Arroyo S,Cabre N,Luciano-Mateo F,Baiges-Gaya G,Fibla M,Martín-Paredero V,Menendez JA,Camps J,Joven J

更新日期：2018-09-20 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/3214105.]. ...

journal_title：Mediators of inflammation

authors： Liang Y,Chen Q,Du W,Chen C,Li F,Yang J,Peng J,Kang D,Lin B,Chai X,Zhou K,Zeng J

更新日期：2017-01-01 00:00:00

abstract：Purpose:To explore the potential of monocyte-to-lymphocyte ratio (MLR) at hospital admission for predicting acute traumatic intraparenchymal hematoma (tICH) expansion in patients with cerebral contusion. Patients and Methods. This multicenter, observational study included patients with available at-hospital admission (...

journal_title：Mediators of inflammation

authors： Sheng J,Li T,Zhuang D,Cai S,Yang J,Ding F,Chen X,Tian F,Huang M,Li L,Li K,Chen W

更新日期：2020-12-28 00:00:00

abstract：:Rheumatoid arthritis (RA) is one of the most common autoimmune diseases caused by abnormal immune activation and immune tolerance. Immunomodulatory cells (ICs) play a critical role in the maintenance and homeostasis of normal immune function and in the pathogenesis of RA. The human gastrointestinal tract is inhabited ...

journal_title：Mediators of inflammation

authors： Xu H,Zhao H,Fan D,Liu M,Cao J,Xia Y,Ju D,Xiao C,Guan Q

更新日期：2020-09-09 00:00:00

abstract：:Increasing evidence has demonstrated that reactive oxygen species (ROS) induces oxidative stress and plays a crucial role in the pathogenesis of acute pancreatitis (AP). Hydrogen-rich saline (HRS), a well-known ROS scavenger, has been shown to possess therapeutic benefit on AP in many animal experiments. Recent findin...

journal_title：Mediators of inflammation

authors： Ren JD,Ma J,Hou J,Xiao WJ,Jin WH,Wu J,Fan KH

更新日期：2014-01-01 00:00:00

abstract：:Periodontitis is a kind of chronic inflammatory disease that affects the tooth-supporting tissues. ET-1 is related to periodontitis and involved in the regulation of cytokines, but the mechanisms remain unclear. The aim of this study is to investigate how ET-1 affects proinflammatory cytokine expression and differenti...

journal_title：Mediators of inflammation

authors： Liang L,Zhou W,Yang N,Yu J,Liu H

更新日期：2016-01-01 00:00:00

abstract：:The metabolic syndrome is a cluster of cardiometabolic alterations that include the presence of arterial hypertension, insulin resistance, dyslipidemia, and abdominal obesity. Obesity is associated with a chronic inflammatory response, characterized by abnormal adipokine production, and the activation of proinflammato...

journal_title：Mediators of inflammation

authors： Fuentes E,Fuentes F,Vilahur G,Badimon L,Palomo I

更新日期：2013-01-01 00:00:00

abstract：:Fibrosis of oesophagus, lungs, heart, and kidney in the course of systemic sclerosis (SSc) may lead to dysfunction of the above organs or even patients death. Recent studies point out the role of angiogenesis and fibrosis disturbances in the pathogenesis of SSc. Heart fibrosis is one of the most important prognostic f...

journal_title：Mediators of inflammation

authors： Dziankowska-Bartkowiak B,Waszczykowska E,Zalewska A,Sysa-Jedrzejowska A

更新日期：2005-08-14 00:00:00

abstract：:The pivotal role of epithelial cells is to secrete and absorb ions and water in order to allow the formation of a luminal fluid compartment that is fundamental for the epithelial function as a barrier against environmental factors. Importantly, epithelial cells also take part in the innate immune system. As a first li...

journal_title：Mediators of inflammation

authors： Schnúr A,Hegyi P,Rousseau S,Lukacs GL,Veit G

更新日期：2016-01-01 00:00:00

abstract：:Alcohol-related disorders are one of the challenging current health problems with medical, social, and economic consequences. Endotoxemia, oxidative stress, and release of a variety of inflammatory molecules are established mediators in alcoholic liver injury (ALD). Probiotics like L. plantarum though were reported to...

journal_title：Mediators of inflammation

authors： Arora S,Kaur IP,Chopra K,Rishi P

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Coronary atherosclerotic heart disease (CHD) is one of the major concerns in type 2 diabetes (T2D). The systemic chronic inflammation has been postulated to bridge the increased risk of cardiovascular disease and T2D. We formulated that increased peripheral proinflammatory T helper subsets contributed to the...

journal_title：Mediators of inflammation

authors： Zhao RX,Li WJ,Lu YR,Qin J,Wu CL,Tian M,He TY,Yi SN,Tang DQ,Sun L,Chen L

更新日期：2014-01-01 00:00:00

abstract：Background:Gut microbiota is implied in obesity, because of its ability to harvest energy from diet, and in the regulation of behavior. Given the link between gut microbiota, body composition, obesity, and anxiety, the aim of this study was to evaluate the effects of a new psychobiotic formulation. Methods:Eligible pa...

journal_title：Mediators of inflammation

authors： Colica C,Avolio E,Bollero P,Costa de Miranda R,Ferraro S,Sinibaldi Salimei P,De Lorenzo A,Di Renzo L

更新日期：2017-01-01 00:00:00

abstract：:The destruction of joints caused by rheumatoid arthritis and osteoarthritis is characterized by an imbalance of enzyme catalysed cartilage breakdown and regeneration. A complex cytokine network perpetuates joint conditions by direct regulation of metalloproteases, by indirect recruitment of cells that secrete degradat...

journal_title：Mediators of inflammation

authors： Sipe JD,Martel-Pelletier J,Otterness IG,Pelletier JP

更新日期：1994-01-01 00:00:00

abstract：:Adipose tissue produces a wide range of proteins that may influence the immune system. In this study, we assessed the serum levels of leptin, adiponectin, and ghrelin, in association with the measurements of body composition, in 15 female patients with various autoimmune diseases (systemic lupus erythematosus, primary...

journal_title：Mediators of inflammation

authors： Toussirot E,Gaugler B,Bouhaddi M,Nguyen NU,Saas P,Dumoulin G

更新日期：2010-01-01 00:00:00

abstract：:Obesity-induced skeletal muscle inflammation is characterized by increased macrophage infiltration and inflammatory cytokine production. In this study, we investigated whether 4-1BB, a member of the TNF receptor superfamily (TNFRSF9) that provides inflammatory signals, participates in obesity-induced skeletal muscle i...

journal_title：Mediators of inflammation

authors： Le NH,Kim CS,Tu TH,Choi HS,Kim BS,Kawada T,Goto T,Park T,Park JH,Yu R

更新日期：2013-01-01 00:00:00

abstract：:Peptide 204-212 of lipocortin (LC) 5 inhibited porcine pancreatic phospholipase A(2) (PLA(2)) induced rat stomach strip contractions and ADP induced rabbit platelet aggregation in a concentration dependent manner (IC(30) of 10 muM and 400 muM, respectively). The first two amino acids are not necessary since the eptape...

journal_title：Mediators of inflammation

authors： Mugridge KG,Becherucci C,Parente L,Perretti M

更新日期：1993-01-01 00:00:00

abstract：:This study investigated the protective effects of intravitreal Resolvin D1 (RvD1) against LPS-induced rat endotoxic uveitis (EIU). RvD1 was administered into the right eye at a single injection of 5 μL volume containing 10-100-1000 ng/kg RvD1 1 h post-LPS injection (200 μg, Salmonella minnesota) into thefootpad of Spr...

journal_title：Mediators of inflammation

authors： Rossi S,Di Filippo C,Gesualdo C,Potenza N,Russo A,Trotta MC,Zippo MV,Maisto R,Ferraraccio F,Simonelli F,D'Amico M

更新日期：2015-01-01 00:00:00

abstract：:Paricalcitol, a selective vitamin D receptor (VDR) activator used for treatment of secondary hyperparathyroidism in chronic kidney disease (CKD), has been associated with survival advantages, suggesting that this drug, beyond its ability to suppress parathyroid hormone, may have additional beneficial actions. In this ...

journal_title：Mediators of inflammation

authors： Donate-Correa J,Domínguez-Pimentel V,Méndez-Pérez ML,Muros-de-Fuentes M,Mora-Fernández C,Martín-Núñez E,Cazaña-Pérez V,Navarro-González JF

更新日期：2014-01-01 00:00:00

abstract：:Acute kidney injury (AKI), a clinical syndrome, is a sudden onset of kidney failure that severely affects the kidney tubules. One potential treatment is dexmedetomidine (DEX), a highly selective α2-adrenoreceptor agonist that is used as an anesthetic adjuvant. It also has anti-inflammatory, neuroprotective, and sympat...

journal_title：Mediators of inflammation

authors： Bao N,Dai D

更新日期：2020-04-03 00:00:00

abstract：:Leptin participates in the inflammatory responses in multiple cell types and animal models. Chronic cerebral hypoperfusion (CCH) induces inflammation in the central nervous system (CNS), which acts as one of the main reasons for CCH-induced white matter lesions (WMLs). But whether leptin participates in the pathogenes...

journal_title：Mediators of inflammation

authors： Du Y,Song Y,Zhang X,Luo Y,Zou W,Zhang J,Fu J

更新日期：2020-12-18 00:00:00

abstract：:We investigated the influence of 2-chlorodeoxyadenosine (2-CdA) in combination with tumour necrosis factor-alpha (TNFalpha) or its mutein VI, which differs from the native molecule by N-terminal amino acid composition, on the survival time of mice inoculated with leukaemia L1210 or P388. Groups of mice with leukaemia ...

journal_title：Mediators of inflammation

authors： Góra-Tybor J,Warzocha K,Robak T

更新日期：1995-01-01 00:00:00

abstract：:Inflammatory bowel diseases (IBD) are multifactorial disorders resulting from environmental and genetic factors. Polymorphisms in MDR1 and GSTs genes might explain individual differences in susceptibility to IBD. We carried out a case-control study to examine the association of MDR1 (C1236T and C3435T), GSTT1, and GST...

journal_title：Mediators of inflammation

authors： Senhaji N,Kassogue Y,Fahimi M,Serbati N,Badre W,Nadifi S

更新日期：2015-01-01 00:00:00

abstract：:Diabetic retinopathy is considered a neurovascular disorder, hyperglycemia being considered the main risk factor for this pathology. Diabetic retinopathy also presents features of a low-grade chronic inflammatory disease, including increased levels of cytokines in the retina, such as interleukin-1 beta (IL-1β). Howeve...

journal_title：Mediators of inflammation

authors： Baptista FI,Aveleira CA,Castilho ÁF,Ambrósio AF

更新日期：2017-01-01 00:00:00

abstract：:Cytokines play an important role in the regulation of the immune system (adaptive and innate). Given their importance in proinflammatory processes, cytokines have been used for understanding the pathogenesis and as biomarkers in many diseases. IL-31 and IL-33 are still considered novel cytokines. IL-31 controls signal...

journal_title：Mediators of inflammation

authors： Di Salvo E,Ventura-Spagnolo E,Casciaro M,Navarra M,Gangemi S

更新日期：2018-03-11 00:00:00

abstract：BACKGROUND:Studies on peripheral benzodiazepine receptor function have yielded a diverse list of activities of which the anti-inflammatory effects need to be further examined. AIMS:To evaluate the role of steroids, nitric oxide and adenosine-deaminase in the anti-inflammatory effect of PK11195. METHODS:Pleurisy was i...

journal_title：Mediators of inflammation

authors： da Silva MB,Farges RC,Fröde TS

更新日期：2004-04-01 00:00:00

abstract：:Inflammation is considered to be one of the most critical factors involved in the development of complex metabolic diseases such as type 2 diabetes, cancer, and cardiovascular disease. A few decades ago, the discovery of mitochondria-associated endoplasmic reticulum (ER) membrane (MAM) was followed by the identificati...

journal_title：Mediators of inflammation

authors： Thoudam T,Jeon JH,Ha CM,Lee IK

更新日期：2016-01-01 00:00:00

abstract：:The pathogenesis of brain inflammation and damage by human immunodeficiency virus (HIV) infection is unclear. Because blood-brain barrier damage and impaired cerebral perfusion are common features of HIV-1 infection, we evaluated the role of tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) in ...

journal_title：Mediators of inflammation

authors： Sharief MK,Ciardi M,Thompson EJ,Sorice F,Rossi F,Vullo V,Cirelli A

更新日期：1992-01-01 00:00:00

abstract：:Chronic kidney disease (CKD) patients, characterized by traditional and nontraditional risk factors, are prone to develop atheromatosis and thus cardiovascular events and mortality. The angiogenesis of the adventitial vasa vasorum (aVV) surrounding the carotid has been described as the atheromatosis initiator. Therefo...

journal_title：Mediators of inflammation

authors： Arcidiacono MV,Martinez-Alonso M,Belart M,Vilar A,Martín M,Craver L,Betriu À,Mauricio D,Valdivielso JM,Fernández E,Borràs M

更新日期：2017-01-01 00:00:00

abstract：:In this study, we investigated in groups of female BALB/c mice injected with Crotalus durissus terrificus venom (Cdt) the renal function based on creatinine clearance, percentage of fractional excretion cytokines and histological examination of renal tissue. Cdt caused renal alterations that induced proteinuria during...

journal_title：Mediators of inflammation

authors： Hernández Cruz A,Barbosa Navarro L,Mendonça RZ,Petricevich VL

更新日期：2011-01-01 00:00:00

abstract：:Development of solid cancer depends on escape from host immunosurveillance. Various types of immune cells contribute to tumor-induced immune suppression, including tumor associated macrophages, regulatory T cells, type 2 NKT cells, and myeloid-derived suppressor cells (MDSCs). Growing body of evidences shows that MDSC...

journal_title：Mediators of inflammation

authors： Katoh H,Watanabe M

更新日期：2015-01-01 00:00:00