Abstract:
:[This corrects the article DOI: 10.1155/2016/3214105.].
journal_name
Mediators Inflammjournal_title
Mediators of inflammationauthors
Liang Y,Chen Q,Du W,Chen C,Li F,Yang J,Peng J,Kang D,Lin B,Chai X,Zhou K,Zeng Jdoi
10.1155/2017/2917134subject
Has Abstractpub_date
2017-01-01 00:00:00pages
2917134eissn
0962-9351issn
1466-1861journal_volume
2017pub_type
已发布勘误abstract::As a noninvasive method, exhaled breath condensate (EBC) has gained importance to improve monitoring of lung diseases and to detect biomarkers. The aim of the study was to investigate, whether erythropoietin (EPO) is detectable in EBC. EBC was collected from 22 consecutive patients as well as from healthy individuals....
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/MI/2006/18061
更新日期:2006-01-01 00:00:00
abstract::A prominent feature of inflammatory diseases is endothelial dysfunction. Factors associated with endothelial dysfunction include proinflammatory cytokines, adhesion molecules, and matrix degrading enzymes. At the transcriptional level, they are regulated by the histone deacetylase sirtuin (SIRT) 1 via its actions on t...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2012/597514
更新日期:2012-01-01 00:00:00
abstract::Peripheral artery disease (PAD) is a common disease affecting 20-25% of population over 60 years old. Early diagnosis is difficult because symptoms only become evident in advanced stages of the disease. Inflammation, impaired metabolism, and mitochondrial dysfunction predispose to PAD, which is normally associated wit...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2018/2760272
更新日期:2018-09-20 00:00:00
abstract:Objective:For patients with severe acute pancreatitis (SAP), a high body mass index (BMI) increases the possibility of infection derived from the intestine. In this study, we evaluate whether TAK242 can alleviate severe acute pancreatitis-associated injury of intestinal barrier in high-fat diet-fed rats. Methods:A SAP...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2019/2512687
更新日期:2019-12-17 00:00:00
abstract::The present study investigated the frequencies of rs1800450 (MBL ⁎B, G>A), rs1800451 (MBL ⁎C, G>A), and rs5030737 (MBL ⁎D, C>T) polymorphisms in exon 1 of the MBL2 gene among patients with chronic viral hepatitis. Blood samples from patients infected with hepatitis B virus (HBV; n = 65), hepatitis C virus (HCV; n = 92...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2017/3718451
更新日期:2017-01-01 00:00:00
abstract:AIMS:This retrospective analysis was aimed at evaluating the effectiveness of treatment of persistent diabetic macular edema with intravitreal injections of 0.7 mg dexamethasone implant Ozurdex. The study comprised three male patients (6 eyes). RESULTS:The average thickness of the retina at baseline was 632 μm, the m...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2014/364143
更新日期:2014-01-01 00:00:00
abstract::Tumor necrosis factor alpha (TNF-α) is a potent proinflammatory cytokine that plays a significant role in the pathogenesis of asthma by inducing hyperresponsiveness and airway remodeling. TNF-α diminishes the L-type voltage dependent Ca(2+) channel (L-VDCC) current in cardiac myocytes, an observation that seems parado...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2016/5972302
更新日期:2016-01-01 00:00:00
abstract::The apoptosis-associated speck-like protein containing a caspase recruit domain (ASC) is involved in apoptosis and innate immunity and is a major adaptor molecule responsible for procaspase-1 activation. ASC mRNA is encoded by three exons: exons 1 and 3 encode a pyrin domain (PYD) and caspase recruit domain (CARD), re...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2009/287387
更新日期:2009-01-01 00:00:00
abstract::Human fibroblast-like synoviocytes play a vital role in joint synovial inflammation in rheumatoid arthritis (RA). Proinflammatory cytokines induce fibroblast-like synoviocyte activation and dysfunction. The inflammatory mediator Krüppel-like factor 4 is upregulated during inflammation and plays an important role in en...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2016/1062586
更新日期:2016-01-01 00:00:00
abstract::Matrix metalloproteinase-14 (MMP-14) promotes vulnerable plaque morphology in mice, whereas tissue inhibitor of metalloproteinases-3 (TIMP-3) overexpression is protective. MMP-14(hi) TIMP-3(lo) rabbit foam cells are more invasive and more prone to apoptosis than MMP-14(lo) TIMP-3(hi) cells. We investigated the implica...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2014/276457
更新日期:2014-01-01 00:00:00
abstract::Inflammation represents the immune system response to external or internal aggressors such as injury or infection in certain tissues. The body's response to cancer has many parallels with inflammation and repair; the inflammatory cells and cytokines present in tumours are more likely to contribute to tumour growth, pr...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2013/979748
更新日期:2013-01-01 00:00:00
abstract::Severe acute pancreatitis (SAP) characterized by atrocious progression and numerous complications often leads to a high mortality rate due to hypermetabolism, systemic inflammatory response syndrome (SIRS), and multiple organs dysfunction syndrome (MODS). Studies have revealed that both early enteral nutrition (EEN) a...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2007/29638
更新日期:2007-01-01 00:00:00
abstract::The causes of retinal hypoxia are many and varied. Under hypoxic conditions, a variety of soluble factors are secreted into the vitreous cavity including growth factors, cytokines, and chemokines. Cytokines, which usually serve as signals between neighboring cells, are involved in essentially every important biologica...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2013/935301
更新日期:2013-01-01 00:00:00
abstract::Acute kidney injury (AKI), a clinical syndrome, is a sudden onset of kidney failure that severely affects the kidney tubules. One potential treatment is dexmedetomidine (DEX), a highly selective α2-adrenoreceptor agonist that is used as an anesthetic adjuvant. It also has anti-inflammatory, neuroprotective, and sympat...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2020/2120971
更新日期:2020-04-03 00:00:00
abstract:OBJECTIVE:Individuals with inflammation have a myriad of pregnancy aberrations including increasing their preterm birth risk. Toll-like receptors (TLRs) and receptor for advanced glycation end products (RAGE) and their ligands were all found to play a key role in inflammation. In the present study, we reviewed TLR and ...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2010/490406
更新日期:2010-01-01 00:00:00
abstract::Periodontitis is an inflammatory disease characterized by destruction of the tooth-supporting tissues. Obese individuals have an increased risk of periodontitis, and elevated circulating levels of nicotinamide phosphoribosyltransferase (NAMPT) may be a pathomechanistic link between both diseases. Recently, increased l...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2013/202530
更新日期:2013-01-01 00:00:00
abstract::Long-term exposure to crystalline silica leads to silicosis, which is characterized by persistent lung inflammation and lung fibrosis. Multiple immune cells have been demonstrated to participate in crystalline silica-induced immune responses. Our previous study indicated that B10 could control lung inflammation throug...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2017/8415094
更新日期:2017-01-01 00:00:00
abstract::Human gingival fibroblast barrier dysfunction caused by inflammation contributes to gingivitis and can lead to inflammatory periodontal disease. The disease features include upregulated epithelial permeability, increased inflammatory mediators, and downregulated junctional complex molecules. Carbon monoxide- (CO-) rel...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2020/6302391
更新日期:2020-04-28 00:00:00
abstract::Galectin-1 (Gal-1), an evolutionarily conserved β-galactoside-binding lectin, controls immune cell homeostasis and tempers acute and chronic inflammation by blunting proinflammatory cytokine synthesis, engaging T-cell apoptotic programs, promoting expansion of T regulatory (Treg) cells, and deactivating antigen-presen...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2018/8696543
更新日期:2018-11-05 00:00:00
abstract::The objective of this study was to evaluate the effects of peptides derived from synbiotics on improving inflammatory bowel disease (IBD). Five-week-old male C57BL/6 mice were administered with dextran sulfate sodium (DSS) via drinking water for seven days to induce IBD (IBD group). The mice in the IBD group were oral...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2020/3572809
更新日期:2020-07-04 00:00:00
abstract::Adipose tissue produces a wide range of proteins that may influence the immune system. In this study, we assessed the serum levels of leptin, adiponectin, and ghrelin, in association with the measurements of body composition, in 15 female patients with various autoimmune diseases (systemic lupus erythematosus, primary...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2010/938408
更新日期:2010-01-01 00:00:00
abstract::Fat loss is associated with shorter survival and reduced quality of life in cancer patients. Effective intervention for fat loss in cachexia requires identification of the condition using prognostic biomarkers for early detection and prevention of further depletion. No biomarkers of fat mass alterations have been defi...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2015/820934
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Airway smooth muscle (ASM) is considered to be a target for mediators released during airway inflammation. AIMS:To investigate the expression of c-fos, a constituent of the transcription factor activator protein-1, in human ASM cells. In addition, to measure the release of interleukin (IL)-6 into the condit...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1080/09629350124155
更新日期:2001-06-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2018/3809092.]. ...
journal_title:Mediators of inflammation
pub_type: 杂志文章,已发布勘误
doi:10.1155/2019/4524179
更新日期:2019-06-18 00:00:00
abstract::Delayed rectifier K(+)-channels (Kv1.3) are predominantly expressed in T lymphocytes. Based on patch-clamp studies, the channels play crucial roles in facilitating the calcium influx necessary to trigger lymphocyte activation and proliferation. Using selective channel inhibitors in experimental animal models, in vivo ...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2015/436572
更新日期:2015-01-01 00:00:00
abstract::Current studies have identified the multifaceted protective functions of dexmedetomidine on multiple organs. For the first time, we clarify effects of dexmedetomidine on monocyte-endothelial adherence and whether its underlying mechanism is relative to connexin43 (Cx43), a key factor regulating monocyte-endothelial ad...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2020/7039854
更新日期:2020-02-10 00:00:00
abstract::Little work is done to develop Aloe vera (AV) using probiotics. To explore the potential benefits, the antioxidant effects and the antibacterial effects on foodborne pathogens of Aloe fermentation supernatant were evaluated in vitro. Our results indicated that the Aloe fermentation supernatant fermented by Lactobacill...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2016/2945650
更新日期:2016-01-01 00:00:00
abstract::The close relationship between increased TLR-2 expression in blood monocytes and insulin resistance in RA patients is shown in this study. Traditional risk factors for metabolic disorders, including the waist circumstance, body mass index (BMI), triglyceride (TG), and ratio of TG to high density lipoprotein (HDL) chol...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2012/690525
更新日期:2012-01-01 00:00:00
abstract::Vascular complications of diabetes mellitus represent a major public health problem. Although many steps forward have been made to define the causes and to find the best possible therapies, the problem remains crucial. In recent years, more and more evidences have defined a link between microbiota and the initiation, ...
journal_title:Mediators of inflammation
pub_type: 杂志文章,评审
doi:10.1155/2019/4128682
更新日期:2019-05-08 00:00:00
abstract::Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host's proteins. Antigens and their immune complexes (IC) may shape macrophage phenotype in various directions. Data on the impact of protein structure during inflammati...
journal_title:Mediators of inflammation
pub_type: 杂志文章
doi:10.1155/2018/7501985
更新日期:2018-11-18 00:00:00