Abstract:
:We compared the electrodiagnostic studies of 40 patients with chronic acquired demyelinative neuropathy and 18 patients with familial demyelinative neuropathy. Patients with acquired neuropathy had differential slowing of conduction velocity when distal latencies were compared with more proximal conduction velocities in the same nerve, when equivalent segments of different nerves were compared, and when dispersion of compound motor action potentials was examined. Conduction block was noted in some patients. Patients with familial disease had uniform conduction slowly of all nerve segments, and conduction block was not seen. Chronic acquired demyelinative neuropathy is characterized by multifocal slowing of nerve conduction, whereas familial demyelinative neuropathy is characterized by uniform conduction slowing.
journal_name
Neurologyjournal_title
Neurologyauthors
Lewis RA,Sumner AJdoi
10.1212/wnl.32.6.592subject
Has Abstractpub_date
1982-06-01 00:00:00pages
592-6issue
6eissn
0028-3878issn
1526-632Xjournal_volume
32pub_type
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