Diagnostic value of myotactic reflexes in axonal and demyelinating polyneuropathy.

abstract：OBJECTIVE:In the work-up of patients presenting with a clinically isolated syndrome (CIS), 3T MRI might offer a higher lesion detection than 1.5T, but it remains unclear whether this affects the fulfilment of the diagnostic criteria for multiple sclerosis (MS). METHODS:We recruited 66 patients with CIS within 6 months...

journal_title：Neurology

authors： Hagens MHJ,Burggraaff J,Kilsdonk ID,de Vos ML,Cawley N,Sbardella E,Andelova M,Amann M,Lieb JM,Pantano P,Lissenberg-Witte BI,Killestein J,Oreja-Guevara C,Ciccarelli O,Gasperini C,Lukas C,Wattjes MP,Barkhof F,MAGNIMS St

更新日期：2018-07-17 00:00:00

abstract：:In many parkinsonian syndromes, neuromelanin (NM)-containing dopaminergic neurons of the substantia nigra (SN) are selectively targeted by the noxius pathogens. Studies of the constitutional and functional features of human NM allow the formulation of a logical hypothesis on its role in parkinsonian syndromes. In the ...

journal_title：Neurology

authors： Zecca L,Zucca FA,Albertini A,Rizzio E,Fariello RG

更新日期：2006-10-10 00:00:00

abstract：:Two adult brothers became ill within 48 hours of each other, and both had severe myoglobinuria. One brother died of oliguric renal failure. The other did not have renal failure and survived. Acute influenza A infection was documented serologically and from throat washings in the surviving brother, and by isolation of ...

journal_title：Neurology

authors： Zamkoff K,Rosen N

更新日期：1979-03-01 00:00:00

abstract：OBJECTIVE:To understand the experience and identify drivers and mitigating factors of burnout and well-being among US neurologists. METHODS:Inductive data analysis was applied to free text comments (n = 676) from the 2016 American Academy of Neurology survey of burnout, career satisfaction, and well-being. RESULTS:Re...

journal_title：Neurology

authors： Miyasaki JM,Rheaume C,Gulya L,Ellenstein A,Schwarz HB,Vidic TR,Shanafelt TD,Cascino TL,Keran CM,Busis NA

更新日期：2017-10-17 00:00:00

abstract：:A seismic shift in our understanding of the ability to diagnose Alzheimer disease (AD) is occurring. For the last several decades, AD has been a clinical-pathologic diagnosis, and this conceptualization of the disease has served the field well. Typically, the clinician would identify a syndrome such as mild cognitive ...

journal_title：Neurology

authors： Petersen RC

更新日期：2018-08-28 00:00:00

abstract：:Four patients developed postural tremor after ingestion of sodium valproate. The tremor was recorded by a variable-capacitance transducer and was of the "benign essential" type. The dosages of sodium valproate varied between 1000 mg and 2000 mg daily and serum levels were between 34.9 microgram per milliliter and 154....

journal_title：Neurology

authors： Hyman NM,Dennis PD,Sinclair KG

更新日期：1979-08-01 00:00:00

abstract：:Article abstract Depressive disorders (DDs) are the most common type of psychiatric co-morbidity in patients with epilepsy. They are more likely to occur in patients with partial seizure disorders of temporal and frontal lobe origin and are more frequent among patients with poorly controlled seizures. Despite their re...

journal_title：Neurology

authors： Kanner AM,Balabanov A

更新日期：2002-04-23 00:00:00

abstract：OBJECTIVE:To elucidate the phenotype, genotype, and MRI findings of Korean patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and mutation carriers. METHODS:The authors studied 40 members of nine unrelated Korean CADASIL families. After genetic analysis o...

journal_title：Neurology

authors： Kim Y,Choi EJ,Choi CG,Kim G,Choi JH,Yoo HW,Kim JS

更新日期：2006-05-23 00:00:00

abstract：OBJECTIVE:To assess the role of CHCHD2 variants in patients with Parkinson disease (PD) and Lewy body disease (LBD) in Caucasian populations. METHODS:All exons of the CHCHD2 gene were sequenced in a US Caucasian patient-control series (878 PD, 610 LBD, and 717 controls). Subsequently, exons 1 and 2 were sequenced in a...

journal_title：Neurology

authors： Ogaki K,Koga S,Heckman MG,Fiesel FC,Ando M,Labbé C,Lorenzo-Betancor O,Moussaud-Lamodière EL,Soto-Ortolaza AI,Walton RL,Strongosky AJ,Uitti RJ,McCarthy A,Lynch T,Siuda J,Opala G,Rudzinska M,Krygowska-Wajs A,Barcikowska

更新日期：2015-12-08 00:00:00

abstract：OBJECTIVE:To validate the ability of a specifically developed cognitive risk score to identify patients at risk of poststroke neurocognitive disorders (NCDs) who are eligible for a comprehensive cognitive assessment. METHODS:After assessing 404 patients (infarct 91.3%) in the Groupe de Réflexion pour l'Evaluation Cogn...

journal_title：Neurology

authors： Godefroy O,Yaïche H,Taillia H,Bompaire F,Nédélec-Ciceri C,Bonnin C,Varvat J,Vincent-Grangette F,Diouf M,Mas JL,Canaple S,Lamy C,Arnoux A,Leclercq C,Tasseel-Ponche S,Roussel M,Barbay M,GRECogVASC Study Group.

更新日期：2018-11-20 00:00:00

abstract：:A 57-year-old chronically immunosuppressed woman with systemic lupus erythematosus developed fulminant meningoencephalitis due to Acanthamoeba castellanii. Amebic trophozoites were also found in the lungs, suggesting a primary pulmonary focus of infection. This case illustrates that Acanthamoeba can cause a fulminant,...

journal_title：Neurology

authors： Grunnet ML,Cannon GH,Kushner JP

更新日期：1981-02-01 00:00:00

abstract：:Educators of the next generation of neurologists will face several challenges, including changes in academic medical centers and hospitals, changes in the scope and practice of neurology itself, and changes in trainees, related to both access to information technology and professional goals. This article, which origin...

journal_title：Neurology

authors： Elkind MS

更新日期：2009-02-17 00:00:00

abstract：:We studied the scalp distribution of auditory event-related potentials (P300), using simultaneously a cephalic (linked ears) and a noncephalic (balanced sternovertebra) reference. The recordings with noncephalic reference showed that infrequent, attended auditory stimuli evoke a negative bitemporal component (N300) as...

journal_title：Neurology

authors： Neshige R,Lüders H

更新日期：1988-11-01 00:00:00

abstract：:Four patients with presumed Tolosa-Hunt syndrome ultimately proved to have a parasellar tumor. All four had manifestations of a cavernous sinus syndrome, normal radiologic and medical investigations, and response to steroid therapy. The Tolosa-Hunt syndrome is a diagnosis of exclusion; many other lesions can simulate ...

journal_title：Neurology

authors： Spector RH,Fiandaca MS

更新日期：1986-02-01 00:00:00

abstract：:A patient with PD who exhibited disabling tremor and prominent dyskinesia underwent deep brain stimulation (DBS) of the left thalamic ventral intermediate nucleus. The electrode migrated and was replaced but with suboptimal clinical response. Two years later, postmortem analysis found the second electrode tip had ente...

journal_title：Neurology

authors： Henderson JM,O'Sullivan DJ,Pell M,Fung VS,Hely MA,Morris JG,Halliday GM

更新日期：2001-06-12 00:00:00

abstract：:Subsequent to publication of the NINDS t-PA Stroke Study results, we sought to determine the proportion of patients eligible for and receiving intravenous tissue plasminogen activator (t-PA) at an active acute stroke treatment center. Over a 12-month period there were 185 stroke code activations. Of these, 134 involve...

journal_title：Neurology

authors： Zweifler RM,Brody ML,Graves GC,U TT,Drinkard R,Cunningham S,Rothrock JF

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:The presence of cranial autonomic symptoms often leads to a misdiagnosis of "sinus headache" in adult migraineurs, leading to unnecessary treatments and delaying appropriate migraine therapy. In this study, we examined the frequency of cranial autonomic symptoms in pediatric/adolescent patients with migraine....

journal_title：Neurology

authors： Gelfand AA,Reider AC,Goadsby PJ

更新日期：2013-07-30 00:00:00

abstract：:We present a clinical and morphological study concerning a kindred with slowly progressive X-linked muscular dystrophy (Becker type). Five males were affected; one died of heart failure at age 16. Severe and early cardiac disorder is unusual in this type of muscular dystrophy, and death at such an early age had not be...

journal_title：Neurology

authors： Kuhn E,Fiehn W,Schröder JM,Assmus H,Wagner A

更新日期：1979-08-01 00:00:00

abstract：OBJECTIVE:To assess the frequency of mutations in C19orf12 in the greater neurodegeneration with brain iron accumulation (NBIA) population and further characterize the associated phenotype. METHODS:Samples from 161 individuals with idiopathic NBIA were screened, and C19orf12 mutations were identified in 23 subjects. D...

journal_title：Neurology

authors： Hogarth P,Gregory A,Kruer MC,Sanford L,Wagoner W,Natowicz MR,Egel RT,Subramony SH,Goldman JG,Berry-Kravis E,Foulds NC,Hammans SR,Desguerre I,Rodriguez D,Wilson C,Diedrich A,Green S,Tran H,Reese L,Woltjer RL,Hayfli

更新日期：2013-01-15 00:00:00

abstract：OBJECTIVE:To investigate clinical, neuropsychological, and MRI abnormalities (gray matter atrophy [GMA] and white matter atrophy [WMA]) in surgical mesial temporal lobe epilepsy (MTLE) patients with and without familial antecedent for epilepsy. METHODS:A cohort study including 69 operated patients with unilateral MTLE...

journal_title：Neurology

authors： Yasuda CL,Morita ME,Alessio A,Pereira AR,Balthazar ML,Saúde AV,Costa AL,Costa AL,Cardoso TA,Betting LE,Guerreiro CA,Damasceno BP,Lopes-Cendes I,Tedeschi H,de Oliveira E,Cendes F

更新日期：2010-03-30 00:00:00

abstract：:Cisplatin, used to treat ovarian, bladder, and testicular cancers, causes a sensory dose-limiting neuropathy. Preliminary observations in humans and animals suggest that nerve damage may be prevented by ACTH analogs, particularly those belonging to the melanocortin class, and by nerve growth factor (NGF). We establish...

journal_title：Neurology

authors： Windebank AJ,Smith AG,Russell JW

更新日期：1994-03-01 00:00:00

abstract：:Unusual late-onset complications of brain irradiation, characterized by reversible neurologic focal signs, seizures, and MRI alterations, have recently been reported and classified as stroke-like migraine attacks after radiation therapy (SMART)(1) and peri-ictal pseudoprogression (PIPG).(2.) ...

journal_title：Neurology

authors： Di Stefano AL,Berzero G,Vitali P,Galimberti CA,Ducray F,Ceroni M,Bastianello S,Colombo AA,Simoncelli A,Brunelli MC,Giometto B,Diamanti L,Gaviani P,Salmaggi A,Silvani A,Marchioni E

更新日期：2013-09-10 00:00:00

abstract：:We report a Japanese Becker muscular dystrophy (BMD) patient with occasional myalgia and cramps during normal activity that developed at the age of 28 months. His family history was negative for neuromuscular diseases. Muscle biopsy analyses, including dystrophin immunostaining, disclosed no clinically relevant findin...

journal_title：Neurology

authors： Ishigaki C,Patria SY,Nishio H,Yabe M,Matsuo M

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To investigate whether admission hyperglycemia predicts poststroke infections and, if so, whether poststroke infections modify the effect of admission hyperglycemia on functional outcome in ischemic stroke. METHODS:We used data from acute ischemic stroke patients in the Preventive Antibiotics in Stroke Study...

journal_title：Neurology

authors： Zonneveld TP,Nederkoorn PJ,Westendorp WF,Brouwer MC,van de Beek D,Kruyt ND,PASS Investigators.

更新日期：2017-04-11 00:00:00

abstract：:We investigated the status of the apolipoprotein E allele in 538 participants in the incidence phase of the ongoing Shanghai Survey of Dementia, including 103 demented subjects, 72 with mild cognitive impairment and 363 cognitively normal. The apo E epsilon 4 allele was present in 10.2% of control subjects and the all...

journal_title：Neurology

authors： Katzman R,Zhang MY,Chen PJ,Gu N,Jiang S,Saitoh T,Chen X,Klauber M,Thomas RG,Liu WT,Yu ES

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between age-associated MRI leukoaraiosis or white matter hyperintensities (WMH) and cortical acetylcholinesterase (AChE) activity. BACKGROUND:One possible mechanism of cognitive decline in elderly individuals with leukoaraiosis is disruption of cholinergic fibers by strategica...

journal_title：Neurology

authors： Bohnen NI,Müller ML,Kuwabara H,Constantine GM,Studenski SA

更新日期：2009-04-21 00:00:00

abstract：BACKGROUND:The pathogenesis of stroke-like episodes in patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) remains unknown. METHODS:Fourteen stroke-like episodes in six patients with MELAS were studied using clinical, neuroradiologic, and electrophysiologic approaches...

journal_title：Neurology

authors： Iizuka T,Sakai F,Suzuki N,Hata T,Tsukahara S,Fukuda M,Takiyama Y

更新日期：2002-09-24 00:00:00

abstract：:The authors used 1H-MRS to investigate hypothalamic metabolism in 26 patients with cluster headache (CH) and 12 healthy subjects. Hypothalamic N-acetylaspartate/creatine was reduced in patients with CH vs controls (p < 0.01). Dividing the patients into episodic CH outside- and in-cluster periods and chronic CH, the hy...

journal_title：Neurology

authors： Lodi R,Pierangeli G,Tonon C,Cevoli S,Testa C,Bivona G,Magnifico F,Cortelli P,Montagna P,Barbiroli B

更新日期：2006-04-25 00:00:00

abstract：OBJECTIVE:The diagnosis of psychogenic nonepileptic seizures (PNES) can be challenging. In the absence of a gold standard to verify the reliability of the diagnosis by EEG-video, we sought to assess the interrater reliability of the diagnosis using EEG-video recordings. METHODS:Patient samples consisted of 22 unselect...

journal_title：Neurology

authors： Benbadis SR,LaFrance WC Jr,Papandonatos GD,Korabathina K,Lin K,Kraemer HC,NES Treatment Workshop.

更新日期：2009-09-15 00:00:00

abstract：OBJECTIVE:To explore the causal relationships between sleep, major depressive disorder (MDD), and Alzheimer disease (AD). METHODS:We conducted bidirectional 2-sample Mendelian randomization analyses. Genetic associations were obtained from the largest genome-wide association studies currently available in UK Biobank (...

journal_title：Neurology

authors： Huang J,Zuber V,Matthews PM,Elliott P,Tzoulaki J,Dehghan A

更新日期：2020-10-06 00:00:00