Abstract：
:The current validated endotoxin detection methods, in spite of being highly sensitive, present several drawbacks in terms of reproducibility, handling and cost. Therefore novel approaches are being carried out in the scientific community to overcome these difficulties. Remarkable efforts are focused on the development of endotoxin-specific biosensors. The key feature of these solutions relies on the proper definition of the capture protocol, especially of the bio-receptor or ligand. The aim of the presented work is the screening and selection of a synthetic peptide specifically designed for LPS detection, as well as the optimization of a procedure for its immobilization onto gold substrates for further application to biosensors.
journal_name
J Biotechnoljournal_title
Journal of biotechnologyauthors
Mujika M,Zuzuarregui A,Sánchez-Gómez S,Martínez de Tejada G,Arana S,Pérez-Lorenzo Edoi
10.1016/j.jbiotec.2014.06.018subject
Has Abstractpub_date
2014-09-30 00:00:00pages
162-8eissn
0168-1656issn
1873-4863pii
S0168-1656(14)00309-5journal_volume
186pub_type
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