Abstract：
:The effect of the H-2dm1 mutation on Qa-m2 expression was examined. The mutant strain B10.D2-H-2dm1 showed a fourfold increase in Qa-m2 expression when compared with the parental strain B10.D2. Qa-m2 molecules immunoprecipitated from B10.D2-H-2dm1, C57BL/10, and B10.D2 spleen cells were identical by two-dimensional (2-D) gel electrophoresis [isoelectric focusing (IEF) followed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE]). It is likely therefore that the increased Qa-m2 expression is not due to gross structural alterations of the Qa-m2 molecule; in the present study, alternative explanations are discussed.
journal_name
Immunogeneticsjournal_title
Immunogeneticsauthors
Hogarth PM,Walker ID,Rigby AJ,McKenzie IFdoi
10.1007/BF00345969subject
Has Abstractpub_date
1983-01-01 00:00:00pages
617-24issue
6eissn
0093-7711issn
1432-1211journal_volume
18pub_type
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