Abstract:
:The classical concepts pertaining to the natural history of mammary carcinoma and its treatment must be reviewed if survival rate is to be improved. By the time diagnosis is established, a fair amount of cases of carcinoma of the breast present distant, clinically undetectable micrometastases, which will not be affected by local therapy (surgery or radiation). Increasing evidence shows that mammary carcinoma nowadays must be looked upon as a diffuse disease affecting both breasts. Postoperative radiation does not improve the 5- and 10-year survival rates and has a negative effect upon the immunological defense of the patient. Immunology plays an important role in the evolution and cure of the patient with carcinoma of the breast. The mutilation produced by radical or ultraradical mastectomy may throw the patient into mental depression which, as a consequence, may decrease the immunological competence of the patient. Multiple drug chemotherapy, started at the time of surgery and continued for several months thereafter, may kill micrometastases. Preventive immunotherapy seems to be beneficial to the patient in attempting control of metastases.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Gentil F,Callia W,de Souza e Sá A,Cavalcanti S,Garcia E,Giannotti Filho O,Varella ADdoi
10.1002/jso.2930140211subject
Has Abstractpub_date
1980-01-01 00:00:00pages
173-93issue
2eissn
0022-4790issn
1096-9098journal_volume
14pub_type
杂志文章abstract::Fresh homogenized mammary gland adenocarcinoma (C3HBA) material was subcutaneously inoculated in the anterior right thigh of transplant host mice (C3H/HeJ). When tumors were palpable, the mice were separated into three groups. The test group received biweekly intratumoral injections of Mycobacterium ulcerans filtrate ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930110210
更新日期:1979-01-01 00:00:00
abstract::The clinicopathologic features of a case of adenocarcinoma arising in Meckel's diverticulum are described and compared with the 21 cases reported in the literature. The prognosis is generally poor. However, the patient in the present case was alive and well 1.5 years after diagnosis, despite the fact that the lesion h...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930230111
更新日期:1983-05-01 00:00:00
abstract:INTRODUCTION:Low-heat treated autograft may have an advantage over allograft in that they provide a size-matched and biologically compatible graft. MATERIALS AND METHODS:We compared the graft survival and complications between the low-heat treated autografts (n = 13) and allografts (17) for intercalary reconstruction ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23727
更新日期:2014-12-01 00:00:00
abstract::Neoadjuvant systemic breast cancer therapy is the administration of systemic therapy to eligible breast cancer patients prior to surgery. This treatment modality was developed out of necessity to downstage inoperable tumors, but it has evolved into a tool for breast conservation surgery. The neoadjuvant approach is al...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21696
更新日期:2011-03-15 00:00:00
abstract::Robotic surgical techniques are now being applied in the setting of retroperitoneal lymphadenectomy (RPLND) for testicular cancer. While laparoscopic RPLND has not been widely accepted, reports of robot assisted RPLND (RARPLND) are emerging. This manuscript will review the application of RPLND for testicular cancer, e...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24018
更新日期:2015-12-01 00:00:00
abstract::Breast cancers from 53 patients were explanted in culture, and 39 with two-year or more follow-up and documentable tissue forms of cancer in culture (histoculture) are the subject of this report. Clinicopathologic findings have been correlated with dynamic aspects of the cancers in short-term histocultures, including ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130103
更新日期:1980-01-01 00:00:00
abstract::A case of leiomyosarcoma of a Meckel's diverticulum, presenting as an acute appendicitis, is reported. The literature is reviewed with particular emphasis on current trends in the diagnosis and management of leiomyosarcomas of the small intestine. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320207
更新日期:1986-06-01 00:00:00
abstract:BACKGROUND:Leiomyosarcoma of the inferior vena cava (IVC) is a rare tumor which presents a unique surgical challenge. We present a series of six cases of leiomyosarcoma resection performed with IVC reconstruction. METHODS:Retrospective chart review was performed for patients undergoing initial operative resection of p...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23798
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Radiofrequency ablation (RF) is emerging as new therapeutic method for the management of hepatic tumors. So far the RF-assisted hepatectomy has been described using an electrode initially designed for ablation of unresectable tumors. Herein, we describe a new technique for liver resection using a bipolar rad...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20770
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVES:We reviewed the clinical characteristics and outcomes of patients treated for alveolar soft part sarcoma (ASPS) and analyzed the effect of surgery for patients presenting with and without metastatic disease (DM). METHODS:The SEER Registry was queried for patients with ASPS from 1973-2012. The Kaplan-Meier e...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24183
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:To explore the time and pattern of recurrence of proximal gastric cancer and estimate the risk factors and prognostic factors for it. Considering these risk factors, postoperative adjuvant therapies and follow-up program can be individualized. METHODS:The data of 135 recurrence proximal gastric cancer patients...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23252
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Oxaliplatin is a chemotherapeutic drug for colorectal adenocarcinoma able to extend the indications for resection of colorectal liver metastases. However, the drug may severely injure hepatic sinusoids, inducing a sinusoidal obstruction syndrome in non-tumoral parenchyma with a risk of decreas...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21276
更新日期:2009-06-01 00:00:00
abstract::Surgical resection for selected patients with hepatic metastases from colorectal cancer can cure approximately one-fourth of these patients. The addition of regional chemotherapy as an attempt to improve this statistic has been extensively investigated in clinical trials. As part of a multidisciplinary educational pro...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.10171
更新日期:2003-01-01 00:00:00
abstract::In our previous study on liposome-mediated transfection of the human interferon-beta (HuIFN-beta) gene into subcutaneously implanted human gliomas in nude mice, we found that HuIFN-beta was produced and secreted by the tumor cells and that the growth of solid tumors was completely inhibited. The present study investig...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930590207
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVE:Gastrointestinal stromal tumors (GISTs) occur rarely in the duodenum. The characteristics of duodenal GIST have not been well clarified. The aim of this study is to clarify the characteristics and surgical prognosis of patients with primary duodenal GIST. METHODS:Data of patients with surgically treated prim...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21378
更新日期:2009-12-01 00:00:00
abstract::Most surgical oncologists receive exposure to clinical studies in their fellowships; however they receive little if any practical knowledge as to how to become a clinical researcher. This article will provide a broad introduction to setting up a community based surgical oncology research program with emphasis on the p...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21780
更新日期:2011-09-01 00:00:00
abstract::The serum copper/zinc ratio was measured in 44 patients bearing primary large bowel malignancies. Measurements were repeated following removal of the primary tumour and again at the time of development of clinical evidence of cancer recurrence in order to evaluate the clinical value of the ratio to accurately reflect ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210407
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To evaluate the impact of plasminogen activator (PA) system genes, including urokinase plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms in patients with the cervical neoplasia. METHODS:In total, 336 blood samples were collected...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23072
更新日期:2012-08-01 00:00:00
abstract::A study of the effectiveness of preoperative radiation as an adjuvant for surgery for patients with invasive bladder carcinoma revealed a subpopulation of patients having advanced disease who could not benefit from radiation treatment. The effect of such a group of patients on the efficiency of 2 common nonparametric ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930100111
更新日期:1978-01-01 00:00:00
abstract::Type-2 adenovirus was shown to inhibit the growth of transplantable hamster melanoma in 70% of Syrian hamsters without any injurious effect to the host. Greatest inhibition of tumor formation was seen when animals were injected with 10(6) TCD50 of adenovirus and 2.5 x 10(5) tumor cells, or 10(6) TCD50 of virus and 5.0...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070514
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVES:To investigate the immunoreactivity of TTF-1 and PAX8 in neuroendocrine carcinoma of thymic (TNEC) and pulmonary origins (PNEC), and whether their immunophenotyping could be used to distinguish between NEC of the two sites, as well as prognosis of patients with TNEC. METHODS:Twenty-two cases of TNEC and 20 ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24393
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Identification of functional lymphatic vessels and localization of lymphatic vessels are important for lymphaticovenular anastomosis (LVA). Indocyanine green (ICG) lymphography is useful for localization of superficial lymphatic vessels where dermal backflow is not observed, but not for lymphatic vessels in ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24812
更新日期:2018-02-01 00:00:00
abstract::Serum copper levels (SCL) have been done in 106 patients of squamous cell carcinoma of the cervix and in 15 cases of local recurrences. The mean SCL has been significantly elevated in them in comparison to controls (P less than 0.001). The SCL falls to near normal range following successful therapy. There is a trend t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930220313
更新日期:1983-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Although race and socioeconomic status have been shown to affect outcomes in pancreatic ductal adenocarcinoma (PDAC), the impact of rural residence on the delivery of adjuvant therapy (AT) has not been studied. METHODS:Patients with resected PDAC were identified using the National Cancer Data...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25060
更新日期:2018-06-01 00:00:00
abstract::The last two decades have seen great improvements in the management of patients with germ-cell tumors of the ovary. The initial treatment approach includes conservative surgery and cisplatin-based chemotherapy in most cases. At completion of chemotherapy, the role of second-look surgery remains questionable. We retros...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9098(199605)62:1<40::AID-JSO9>3
更新日期:1996-05-01 00:00:00
abstract:PURPOSE:To investigate the significance of palliative gastrectomy for different types of metastatic gastric cancer patients displaying peritoneal dissemination, hepatic metastasis, distant lymph node metastasis occurring locally during late-stage disease, and multi-organ metastases. METHODS:We performed a retrospectiv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23158
更新日期:2012-12-01 00:00:00
abstract::The latissimus dorsi (LD) muscle has been previously described to repair diaphragmatic defects, but as a "reverse" flap, relying on secondary blood supply from the perforating lumbar vessels rather than primary inflow from the dominant thoracodorsal artery. We report resection of a retroperitoneal synovial sarcoma, wi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20317
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:HydroMARK® is a newly available biopsy marker for image-guided needle biopsies of non-palpable breast lesions. Objective was to determine if the marker could be utilized independently for lesion localization using intra-operative ultrasound alone. METHODS:A single institution retrospective re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22146
更新日期:2012-05-01 00:00:00
abstract::The Noble rat prostatic adenocarcinoma, Nb-Pr-A.I.-II, an androgen-insensitive tumor, is the subject of this experiment. Dose responses were carried out with treatment of these tumors with three doses of adriamycin and two doses of methotrexate. Adriamycin treatment resulted in decreased tumor volume and decreased num...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930240315
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:B7-H4 is a novel molecular B7 ligand that plays an important role as a negative regulator of the T cell-mediated immune response. However, the clinical significance of B7-H4 expression in gastric cancer remains uncertain. Here, we assessed B7-H4 expression in blood of patients with gastric can...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21722
更新日期:2010-12-01 00:00:00